The increase in thyroid cancer incidence during the last four decades is accompanied by a high frequency of BRAF mutations and a sharp increase in RAS mutations.

PubWeight™: 2.17‹?› | Rank: Top 2%

🔗 View Article (PMC 3913801)

Published in J Clin Endocrinol Metab on November 18, 2013

Authors

Chan Kwon Jung1, Mark P Little, Jay H Lubin, Alina V Brenner, Samuel A Wells, Alice J Sigurdson, Yuri E Nikiforov

Author Affiliations

1: Department of Pathology (C.K.J., Y.E.N.), University of Pittsburgh, Pittsburgh, Pennsylvania 15261; Department of Hospital Pathology (C.K.J.), The Catholic University of Korea, Seoul 137-701, Republic of Korea; and Radiation Epidemiology and Biostatistics Branches (J.H.L., A.V.B., M.P.L., A.J.S.), Division of Cancer Epidemiology and Genetics and Cancer Genetics Branch (S.A.W.), National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.

Articles citing this

Integrated genomic characterization of papillary thyroid carcinoma. Cell (2014) 6.05

TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas. J Clin Endocrinol Metab (2014) 1.71

Diagnostic radiography exposure increases the risk for thyroid microcarcinoma: a population-based case-control study. Eur J Cancer Prev (2015) 1.54

A metabolic phenotype based on mitochondrial ribosomal protein expression as a predictor of lymph node metastasis in papillary thyroid carcinoma. Medicine (Baltimore) (2015) 1.49

Current status and future perspectives in differentiated thyroid cancer. Endocrinol Metab (Seoul) (2014) 1.29

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: THE INCREASING INCIDENCE OF THYROID CANCER. Endocr Pract (2015) 1.22

The changing incidence of thyroid cancer. Nat Rev Endocrinol (2016) 0.96

Molecular approaches to thyroid cancer diagnosis. Endocr Relat Cancer (2014) 0.93

The Frequency and Clinical Implications of the BRAF(V600E) Mutation in Papillary Thyroid Cancer Patients in Korea Over the Past Two Decades. Endocrinol Metab (Seoul) (2014) 0.89

Outcome of Large Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features. Thyroid (2017) 0.88

Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test. Mol Cancer Res (2015) 0.87

Clinicopathological features of rare BRAF mutations in Korean thyroid cancer patients. J Korean Med Sci (2014) 0.85

Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model. Oncotarget (2016) 0.84

A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability. Oncotarget (2016) 0.84

Update: the status of clinical trials with kinase inhibitors in thyroid cancer. J Clin Endocrinol Metab (2014) 0.82

Relationship of Focally Amplified Long Noncoding on Chromosome 1 (FAL1) lncRNA with E2F Transcription Factors in Thyroid Cancer. Medicine (Baltimore) (2016) 0.81

Genetic alterations of differentiated thyroid carcinoma in iodine-rich and iodine-deficient countries. Cancer Med (2016) 0.79

Diagnostic Limitation of Fine-Needle Aspiration (FNA) on Indeterminate Thyroid Nodules Can Be Partially Overcome by Preoperative Molecular Analysis: Assessment of RET/PTC1 Rearrangement in BRAF and RAS Wild-Type Routine Air-Dried FNA Specimens. Int J Mol Sci (2017) 0.78

Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition. Oncotarget (2016) 0.77

Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer. Int J Endocrinol (2016) 0.77

The changing characteristics and molecular profiles of papillary thyroid carcinoma over time: a systematic review. Oncotarget (2016) 0.77

Modeling anaplastic thyroid carcinoma in the mouse. Horm Cancer (2014) 0.77

Mutation Profile of Well-Differentiated Thyroid Cancer in Asians. Endocrinol Metab (Seoul) (2015) 0.77

Molecular profiles of papillary thyroid tumors have been changing in the last decades: how could we explain it? J Clin Endocrinol Metab (2014) 0.76

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma. Oncotarget (2016) 0.75

[Surgical relevance of new biomarkers in papillary carcinoma of the thyroid]. Chirurg (2014) 0.75

Prognostic implication of histological features associated with EHD2 expression in papillary thyroid carcinoma. PLoS One (2017) 0.75

An unexpected finding in the resection specimen of a carcinoma of the oral cavity: A case report. Int J Surg Case Rep (2015) 0.75

Mutational Analysis in Pediatric Thyroid Cancer and Correlations with Age, Ethnicity, and Clinical Presentation. Thyroid (2016) 0.75

No considerable changes in papillary thyroid microcarcinoma characteristics over a 30-year time period. BMC Res Notes (2016) 0.75

Clinical and Morphologic Features of ETV6-NTRK3 Translocated Papillary Thyroid Carcinoma in an Adult Population Without Radiation Exposure. Am J Surg Pathol (2017) 0.75

Progress in Endocrine Neoplasia. Clin Cancer Res (2016) 0.75

Overexpression of NOTCH-regulated Ankyrin Repeat Protein is associated with papillary thyroid carcinoma progression. PLoS One (2017) 0.75

Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples. Oncotarget (2016) 0.75

Perspectives of the AMP-activated kinase (AMPK) signalling pathway in thyroid cancer. Biosci Rep (2014) 0.75

MicroRNA-146b: A Novel Biomarker and Therapeutic Target for Human Papillary Thyroid Cancer. Int J Mol Sci (2017) 0.75

LncRNA-SLC6A9-5:2: A potent sensitizer in 131I-resistant papillary thyroid carcinoma with PARP-1 induction. Oncotarget (2017) 0.75

PDE5 Inhibitors-Loaded Nanovesicles: Physico-Chemical Properties and In Vitro Antiproliferative Activity. Nanomaterials (Basel) (2016) 0.75

Thyroid nodules and cancer management guidelines: comparisons and controversies. Endocr Relat Cancer (2016) 0.75

Thyroid nodules ≥ 4 cm: can ultrasound and cytology reliably exclude cancer? Reply. World J Surg (2014) 0.75

Combined analysis of circulating epithelial cells and serum thyroglobulin for distinguishing disease status of the patients with papillary thyroid carcinoma. Oncotarget (2016) 0.75

Targeted next generation sequencing identifies somatic mutations and gene fusions in papillary thyroid carcinoma. Oncotarget (2017) 0.75

NGS based identification of mutational hotspots for targeted therapy in anaplastic thyroid carcinoma. Oncotarget (2017) 0.75

Review of Factors Related to the Thyroid Cancer Epidemic. Int J Endocrinol (2017) 0.75

Articles cited by this

Global cancer statistics, 2002. CA Cancer J Clin (2005) 119.22

Cancer statistics, 2013. CA Cancer J Clin (2013) 84.72

Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA (2006) 22.71

Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980-2005. Cancer Epidemiol Biomarkers Prev (2009) 8.08

Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res (1995) 5.72

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. JAMA (2013) 5.71

Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005. Cancer (2009) 5.55

Radiologic and nuclear medicine studies in the United States and worldwide: frequency, radiation dose, and comparison with other radiation sources--1950-2007. Radiology (2009) 5.48

Risk of thyroid cancer after exposure to 131I in childhood. J Natl Cancer Inst (2005) 5.32

BRAF mutation in papillary thyroid cancer: pathogenic role, molecular bases, and clinical implications. Endocr Rev (2007) 5.21

Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules. J Clin Endocrinol Metab (2009) 3.23

Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children. Cancer Res (1997) 3.06

Molecular genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol (2011) 2.96

Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. J Clin Invest (2005) 2.77

A pathologic re-review of follicular thyroid neoplasms: the impact of changing the threshold for the diagnosis of the follicular variant of papillary thyroid carcinoma. Surgery (2008) 2.21

Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas. Am J Surg Pathol (2006) 2.15

Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. Cancer Lett (2004) 2.00

Changing patterns in the incidence and survival of thyroid cancer with follicular phenotype--papillary, follicular, and anaplastic: a morphological and epidemiological study. Endocr Pathol (2007) 1.92

High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation. Oncogene (1997) 1.91

The most commonly occurring papillary thyroid cancer in the United States is now a microcarcinoma in a patient older than 45 years. Thyroid (2011) 1.85

A time trend analysis of papillary and follicular cancers as a function of tumour size: a study of data from six cancer registries in France (1983-2000). Eur J Cancer (2007) 1.81

Papillary thyroid cancer incidence in the volcanic area of Sicily. J Natl Cancer Inst (2009) 1.80

BRAF mutation in papillary thyroid cancer and its value in tailoring initial treatment: a systematic review and meta-analysis. Medicine (Baltimore) (2012) 1.77

Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications. Clin Cancer Res (2000) 1.72

Analysis of the rising incidence of thyroid cancer using the Surveillance, Epidemiology and End Results national cancer data registry. Surgery (2010) 1.70

RET/PTC rearrangements preferentially occurred in papillary thyroid cancer among atomic bomb survivors exposed to high radiation dose. Cancer Res (2008) 1.67

Incidence trends for papillary thyroid carcinoma and their correlation with thyroid surgery and thyroid fine-needle aspirate cytology. Thyroid (2006) 1.65

Thyroid effects of endocrine disrupting chemicals. Mol Cell Endocrinol (2011) 1.55

Association of high iodine intake with the T1799A BRAF mutation in papillary thyroid cancer. J Clin Endocrinol Metab (2009) 1.55

Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity. J Clin Endocrinol Metab (2006) 1.39

Higher rate of BRAF mutation in papillary thyroid cancer over time: a single-institution study. Cancer (2011) 1.34

Frequent k- ras -2 mutations and p16(INK4A)methylation in hepatocellular carcinomas in workers exposed to vinyl chloride. Br J Cancer (2001) 1.18

Cigarette smoking and K-ras mutations in pancreas, lung and colorectal adenocarcinomas: etiopathogenic similarities, differences and paradoxes. Mutat Res (2009) 1.09

Parental exposure to medications and hydrocarbons and ras mutations in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group. Cancer Epidemiol Biomarkers Prev (2004) 0.99

The presence of BRAF point mutation in adult papillary thyroid carcinomas from atomic bomb survivors correlates with radiation dose. Mol Carcinog (2007) 0.99

Modifications in the papillary thyroid cancer gene profile over the last 15 years. J Clin Endocrinol Metab (2012) 0.98

Is ionizing radiation responsible for the increasing incidence of thyroid cancer? Cancer (2010) 0.93

High prevalence of K-ras-2 mutations in hepatocellular carcinomas in workers exposed to vinyl chloride. Int Arch Occup Environ Health (2001) 0.92

Encapsulated malignant follicular cell-derived thyroid tumors. Endocr Pathol (2010) 0.92

Ras gene mutations in patients with acute myeloid leukaemia and exposure to chemical agents. Carcinogenesis (2003) 0.89

Both K-ras and H-ras protooncogene mutations are associated with Harderian gland tumorigenesis in B6C3F1 mice exposed to isoprene for 26 weeks. Carcinogenesis (1997) 0.83

Etiology of the mutational spectrum of ras genes in human carcinomas. J Natl Cancer Inst (2002) 0.83

Analysis of c-Ha-ras gene mutations in skin tumors induced in carcinogenesis-susceptible and carcinogenesis-resistant mice by different two-stage protocols or tumor promoter alone. Mol Carcinog (2001) 0.83

Mutations in ras genes in experimental tumours of rodents. IARC Sci Publ (1999) 0.83

Clinical behavior of follicular variant of papillary thyroid carcinoma: presentation and survival. Laryngoscope (2010) 0.79

Plastics and carcinogenesis: The example of vinyl chloride. J Carcinog (2012) 0.78

Articles by these authors

Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23

Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study. Lancet (2012) 15.74

Medullary thyroid cancer: management guidelines of the American Thyroid Association. Thyroid (2009) 10.20

High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res (2003) 8.67

Cancer risks attributable to low doses of ionizing radiation: assessing what we really know. Proc Natl Acad Sci U S A (2003) 7.44

A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35

The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust. J Natl Cancer Inst (2012) 5.27

BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary carcinomas. J Clin Endocrinol Metab (2003) 4.93

The Diesel Exhaust in Miners study: a cohort mortality study with emphasis on lung cancer. J Natl Cancer Inst (2012) 4.65

Menopausal hormone replacement therapy and risk of ovarian cancer. JAMA (2002) 4.39

MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility. J Clin Endocrinol Metab (2008) 3.40

Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century. J Clin Endocrinol Metab (2002) 3.06

I-131 dose response for incident thyroid cancers in Ukraine related to the Chornobyl accident. Environ Health Perspect (2011) 2.95

Cancer risks among radiologists and radiologic technologists: review of epidemiologic studies. Radiology (2004) 2.82

A combined analysis of North American case-control studies of residential radon and lung cancer. J Toxicol Environ Health A (2006) 2.78

Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer. J Clin Invest (2005) 2.77

Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. Am J Surg Pathol (2007) 2.75

Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A. N Engl J Med (2005) 2.73

RAS point mutations and PAX8-PPAR gamma rearrangement in thyroid tumors: evidence for distinct molecular pathways in thyroid follicular carcinoma. J Clin Endocrinol Metab (2003) 2.72

American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer. Thyroid (2012) 2.71

Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. Am J Clin Pathol (2003) 2.67

A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study. Ann Occup Hyg (2002) 2.60

Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies. Epidemiology (2005) 2.56

River blindness: a success story under threat? PLoS Med (2006) 2.55

Contribution of molecular testing to thyroid fine-needle aspiration cytology of "follicular lesion of undetermined significance/atypia of undetermined significance". Cancer Cytopathol (2010) 2.55

Mortality from solid cancers among workers in formaldehyde industries. Am J Epidemiol (2004) 2.50

Impact of occupational carcinogens on lung cancer risk in a general population. Int J Epidemiol (2012) 2.46

Trends in the incidence of testicular germ cell tumors in the United States. Cancer (2003) 2.45

Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database. BMJ (2009) 2.42

Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde. J Natl Cancer Inst (2009) 2.42

Thyroid nodules (≥4 cm): can ultrasound and cytology reliably exclude cancer? World J Surg (2014) 2.40

Targeted next-generation sequencing panel (ThyroSeq) for detection of mutations in thyroid cancer. J Clin Endocrinol Metab (2013) 2.34

Methodological issues regarding confounding and exposure misclassification in epidemiological studies of occupational exposures. Am J Ind Med (2007) 2.33

Mortality from solid tumors among workers in formaldehyde industries: an update of the NCI cohort. Am J Ind Med (2013) 2.28

MicroRNA signature distinguishes the degree of aggressiveness of papillary thyroid carcinoma. Ann Surg Oncol (2011) 2.25

Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation. Cancer Res (2005) 2.23

Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas. Am J Surg Pathol (2006) 2.15

Environment And Genetics in Lung cancer Etiology (EAGLE) study: an integrative population-based case-control study of lung cancer. BMC Public Health (2008) 2.02

Low prevalence of BRAF mutations in radiation-induced thyroid tumors in contrast to sporadic papillary carcinomas. Cancer Lett (2004) 2.00

Change in salt intake affects blood pressure of chimpanzees: implications for human populations. Circulation (2007) 1.99

Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis. Oncogene (2005) 1.99

Molecular diagnostics and predictors in thyroid cancer. Thyroid (2009) 1.98

The Diesel Exhaust in Miners Study: IV. Estimating historical exposures to diesel exhaust in underground non-metal mining facilities. Ann Occup Hyg (2010) 1.98

Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries. J Natl Cancer Inst (2003) 1.97

Does gestation vary by ethnic group? A London-based study of over 122,000 pregnancies with spontaneous onset of labour. Int J Epidemiol (2004) 1.97

An application of a weighting method to adjust for nonresponse in standardized incidence ratio analysis of cohort studies. Ann Epidemiol (2005) 1.96

The Diesel Exhaust in Miners Study: III. Interrelations between respirable elemental carbon and gaseous and particulate components of diesel exhaust derived from area sampling in underground non-metal mining facilities. Ann Occup Hyg (2010) 1.95

BRAF V600E mutation independently predicts central compartment lymph node metastasis in patients with papillary thyroid cancer. Ann Surg Oncol (2012) 1.90

Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. Am J Epidemiol (2009) 1.87

Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort. J Natl Cancer Inst (2009) 1.86

RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis. Endocrinology (2006) 1.85

Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis. Expert Rev Mol Diagn (2008) 1.80

Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study. Am J Epidemiol (2004) 1.79

Summary statement from a workshop on asymptomatic primary hyperparathyroidism: a perspective for the 21st century. J Bone Miner Res (2002) 1.79

Variation of second cancer risk by family history of retinoblastoma among long-term survivors. J Clin Oncol (2012) 1.76

Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation. Surgery (2009) 1.72

PAX8-PPARgamma rearrangement in thyroid tumors: RT-PCR and immunohistochemical analyses. Am J Surg Pathol (2002) 1.70

Risk of second primary thyroid cancer after radiotherapy for a childhood cancer in a large cohort study: an update from the childhood cancer survivor study. Radiat Res (2010) 1.68

Genetic variation and willingness to participate in epidemiologic research: data from three studies. Cancer Epidemiol Biomarkers Prev (2005) 1.66

International patterns and trends in testis cancer incidence. Int J Cancer (2005) 1.60

Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiers. Radiat Res (2006) 1.58

Analysis of BRAF point mutation and RET/PTC rearrangement refines the fine-needle aspiration diagnosis of papillary thyroid carcinoma. J Clin Endocrinol Metab (2004) 1.56

Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control study. PLoS One (2009) 1.56

Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors. PLoS Genet (2013) 1.56

Analysis of thyroid malignant pathologic findings identified during 3 rounds of screening (1997-2008) of a cohort of children and adolescents from belarus exposed to radioiodines after the Chernobyl accident. Cancer (2014) 1.55

Persistent organochlorine chemicals in plasma and risk of non-Hodgkin's lymphoma. Cancer Res (2005) 1.55

Risk of cataract after exposure to low doses of ionizing radiation: a 20-year prospective cohort study among US radiologic technologists. Am J Epidemiol (2008) 1.53

Mortality rates among augmentation mammoplasty patients: an update. Epidemiology (2006) 1.52

The role of prophylactic surgery in cancer prevention. World J Surg (2007) 1.51

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study. Breast Cancer Res (2010) 1.51

Systematic review of worldwide variations of the prevalence of wheezing symptoms in children. Environ Health (2008) 1.48

Modeling the probability of arsenic in groundwater in New England as a tool for exposure assessment. Environ Sci Technol (2006) 1.45

An update of cancer incidence in the Agricultural Health Study. J Occup Environ Med (2010) 1.44

The Ukrainian-American study of leukemia and related disorders among Chornobyl cleanup workers from Ukraine: III. Radiation risks. Radiat Res (2008) 1.42

Radiation: a dose of the bomb. Nature (2003) 1.40

Prevalence of RET/PTC rearrangements in thyroid papillary carcinomas: effects of the detection methods and genetic heterogeneity. J Clin Endocrinol Metab (2006) 1.39

Cancer incidence in the agricultural health study. Scand J Work Environ Health (2005) 1.39

Human infection patterns and heterogeneous exposure in river blindness. Proc Natl Acad Sci U S A (2005) 1.38

Candidate single nucleotide polymorphism selection using publicly available tools: a guide for epidemiologists. Am J Epidemiol (2006) 1.37

The mortality risk of smoking and obesity combined. Am J Prev Med (2006) 1.37

Early growth and adult respiratory function in men and women followed from the fetal period to adulthood. Thorax (2006) 1.36

Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas. Int J Surg Pathol (2002) 1.33

RAS mutations are the predominant molecular alteration in poorly differentiated thyroid carcinomas and bear prognostic impact. J Clin Endocrinol Metab (2009) 1.32

Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. Proc Natl Acad Sci U S A (2014) 1.32

Increasing incidence of thyroid cancer: controversies explored. Nat Rev Endocrinol (2013) 1.31

Pesticide use and breast cancer risk among farmers' wives in the agricultural health study. Am J Epidemiol (2005) 1.30

Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinon. Am J Epidemiol (2005) 1.30

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev (2009) 1.29

Arsenic, internal cancers, and issues in inference from studies of low-level exposures in human populations. Toxicol Appl Pharmacol (2007) 1.27

Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation. Clin Cancer Res (2006) 1.27

MicroRNA expression profiles in thyroid tumors. Endocr Pathol (2009) 1.27

Polymorphisms in DNA repair genes, ionizing radiation exposure and risk of breast cancer in U.S. Radiologic technologists. Int J Cancer (2008) 1.26

Maternal blood pressure in pregnancy, birth weight, and perinatal mortality in first births: prospective study. BMJ (2004) 1.26

Dose-dependent generation of RET/PTC in human thyroid cells after in vitro exposure to gamma-radiation: a model of carcinogenic chromosomal rearrangement induced by ionizing radiation. J Clin Endocrinol Metab (2005) 1.24

Cost impact of molecular testing for indeterminate thyroid nodule fine-needle aspiration biopsies. J Clin Endocrinol Metab (2012) 1.24

Second solid cancers after radiation therapy: a systematic review of the epidemiologic studies of the radiation dose-response relationship. Int J Radiat Oncol Biol Phys (2012) 1.24

The Diesel Exhaust in Miners Study: V. Evaluation of the Exposure Assessment Methods. Ann Occup Hyg (2012) 1.23

Molecular analysis of thyroid tumors. Endocr Pathol (2011) 1.23

RAS mutations in thyroid FNA specimens are highly predictive of predominantly low-risk follicular-pattern cancers. J Clin Endocrinol Metab (2013) 1.22