Determination of the 50% human infectious dose for Norwalk virus.

PubWeight™: 2.50‹?› | Rank: Top 2%

🔗 View Article (PMC 3952671)

Published in J Infect Dis on November 18, 2013

Authors

Robert L Atmar1, Antone R Opekun, Mark A Gilger, Mary K Estes, Sue E Crawford, Frederick H Neill, Sasirekha Ramani, Heather Hill, Jennifer Ferreira, David Y Graham

Author Affiliations

1: Department of Medicine.

Associated clinical trials:

New Challenge Pool of Norwalk Virus Inoculum | NCT00138476

Articles citing this

Advances in laboratory methods for detection and typing of norovirus. J Clin Microbiol (2014) 2.31

Comprehensive review of human sapoviruses. Clin Microbiol Rev (2015) 1.48

Norovirus. Clin Microbiol Rev (2015) 1.41

Norovirus in healthcare settings. Curr Opin Infect Dis (2014) 0.98

Mucosal and Cellular Immune Responses to Norwalk Virus. J Infect Dis (2015) 0.96

Innate Susceptibility to Norovirus Infections Influenced by FUT2 Genotype in a United States Pediatric Population. Clin Infect Dis (2015) 0.95

Identification of human single-chain antibodies with broad reactivity for noroviruses. Protein Eng Des Sel (2014) 0.95

Deep sequencing of norovirus genomes defines evolutionary patterns in an urban tropical setting. J Virol (2014) 0.94

Epidemiologic Association Between FUT2 Secretor Status and Severe Rotavirus Gastroenteritis in Children in the United States. JAMA Pediatr (2015) 0.91

Characterization of cross-reactive norovirus-specific monoclonal antibodies. Clin Vaccine Immunol (2014) 0.91

Two human challenge studies confirm high infectivity of Norwalk virus. J Infect Dis (2014) 0.89

Multicenter Evaluation of the Xpert Norovirus Assay for Detection of Norovirus Genogroups I and II in Fecal Specimens. J Clin Microbiol (2015) 0.87

Norovirus immunology: Of mice and mechanisms. Eur J Immunol (2015) 0.85

Experimental human infection with Norwalk virus elicits a surrogate neutralizing antibody response with cross-genogroup activity. Clin Vaccine Immunol (2014) 0.84

Chimeric GII.4 norovirus virus-like-particle-based vaccines induce broadly blocking immune responses. J Virol (2014) 0.83

Sensitive detection of norovirus using phage nanoparticle reporters in lateral-flow assay. PLoS One (2015) 0.81

Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera. PLoS One (2015) 0.79

Vaccine against norovirus. Hum Vaccin Immunother (2014) 0.79

Comparison of concentration methods for quantitative detection of sewage-associated viral markers in environmental waters. Appl Environ Microbiol (2015) 0.78

Vomiting as a Symptom and Transmission Risk in Norovirus Illness: Evidence from Human Challenge Studies. PLoS One (2016) 0.78

Tropical and travel-associated norovirus: current concepts. Curr Opin Infect Dis (2015) 0.78

Aerosolization of a Human Norovirus Surrogate, Bacteriophage MS2, during Simulated Vomiting. PLoS One (2015) 0.78

Development of a Gaussia luciferase-based human norovirus protease reporter system: cell type-specific profile of Norwalk virus protease precursors and evaluation of inhibitors. J Virol (2014) 0.78

Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies. J Clin Microbiol (2015) 0.78

A Gnotobiotic Pig Model for Determining Human Norovirus Inactivation by High-Pressure Processing. Appl Environ Microbiol (2015) 0.78

Pathogenic Enteric Viruses and Microbial Indicators during Secondary Treatment of Municipal Wastewater. Appl Environ Microbiol (2015) 0.77

Recognition of Histo-Blood Group Antigen-Like Carbohydrates in Lettuce by Human GII.4 Norovirus. Appl Environ Microbiol (2016) 0.77

Evaluation of a New Environmental Sampling Protocol for Detection of Human Norovirus on Inanimate Surfaces. Appl Environ Microbiol (2015) 0.77

Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding. PLoS Pathog (2016) 0.77

Control of norovirus outbreak on a pediatric oncology unit. Am J Infect Control (2015) 0.76

Replication of Human Norovirus RNA in Mammalian Cells Reveals Lack of Interferon Response. J Virol (2016) 0.76

Tulane Virus as a Potential Surrogate To Mimic Norovirus Behavior in Oysters. Appl Environ Microbiol (2015) 0.76

Norovirus Regulation by Host and Microbe. Trends Mol Med (2016) 0.75

Wipes coated with a singlet-oxygen-producing photosensitizer are effective against human influenza virus but not against norovirus. Appl Environ Microbiol (2014) 0.75

Digital PCR for Quantifying Norovirus in Oysters Implicated in Outbreaks, France. Emerg Infect Dis (2016) 0.75

Deep sequencing of phage-displayed peptide libraries reveals sequence motif that detects norovirus. Protein Eng Des Sel (2016) 0.75

A Review of State Licensing Regulations to Determine Alignment with Best Practices to Prevent Human Norovirus Infections in Child-Care Centers. Public Health Rep (2016) 0.75

Serological Responses to a Norovirus Nonstructural Fusion Protein after Vaccination and Infection. Clin Vaccine Immunol (2015) 0.75

Reply to Kirby et al. J Infect Dis (2014) 0.75

Norovirus Gastroenteritis in a Birth Cohort in Southern India. PLoS One (2016) 0.75

Preclinical dose-ranging studies of a novel dry powder norovirus vaccine formulation. Vaccine (2016) 0.75

Sensitive Genotyping of Foodborne-Associated Human Noroviruses and Hepatitis A Virus Using an Array-Based Platform. Sensors (Basel) (2017) 0.75

Critical Review on the Public Health Impact of Norovirus Contamination in Shellfish and the Environment: A UK Perspective. Food Environ Virol (2017) 0.75

Articles cited by this

Human susceptibility and resistance to Norwalk virus infection. Nat Med (2003) 7.07

Norwalk virus infection and disease is associated with ABO histo-blood group type. J Infect Dis (2002) 5.09

Typhoid fever: pathogenesis and immunologic control. N Engl J Med (1970) 4.95

Clinical immunity in acute gastroenteritis caused by Norwalk agent. N Engl J Med (1977) 4.80

Norwalk virus infection of volunteers: new insights based on improved assays. J Infect Dis (1994) 4.37

Norwalk virus: how infectious is it? J Med Virol (2008) 3.93

Norovirus vaccine against experimental human Norwalk Virus illness. N Engl J Med (2011) 3.78

Norwalk virus shedding after experimental human infection. Emerg Infect Dis (2008) 3.70

Biological properties of Norwalk agent of acute infectious nonbacterial gastroenteritis. Proc Soc Exp Biol Med (1972) 2.94

Norovirus disease in the United States. Emerg Infect Dis (2013) 2.92

Cellular and humoral immunity following Snow Mountain virus challenge. J Virol (2005) 2.59

Norwalk virus infection associates with secretor status genotyped from sera. J Med Virol (2005) 2.34

Serological correlate of protection against norovirus-induced gastroenteritis. J Infect Dis (2010) 2.21

The Broad Street pump revisited: response of volunteers to ingested cholera vibrios. Bull N Y Acad Med (1971) 2.07

Tissue distribution of histo-blood group antigens. APMIS (2000) 1.94

Detection of murine norovirus 1 by using plaque assay, transfection assay, and real-time reverse transcription-PCR before and after heat exposure. Appl Environ Microbiol (2007) 1.70

Evidence for airborne transmission of Norwalk-like virus (NLV) in a hotel restaurant. Epidemiol Infect (2000) 1.64

Predicting susceptibility to norovirus GII.4 by use of a challenge model involving humans. J Infect Dis (2012) 1.38

Burden of norovirus gastroenteritis in the ambulatory setting--United States, 2001-2009. J Infect Dis (2013) 1.34

Development of an immunomagnetic capture reverse transcription-PCR assay for the detection of Norwalk virus. J Virol Methods (2000) 1.24

Serological responses to experimental Norwalk virus infection measured using a quantitative duplex time-resolved fluorescence immunoassay. Clin Vaccine Immunol (2011) 1.20

Comprehensive analysis of a norovirus-associated gastroenteritis outbreak, from the environment to the consumer. J Clin Microbiol (2010) 1.20

A semiquantitative approach to estimate Norwalk-like virus contamination of oysters implicated in an outbreak. Int J Food Microbiol (2003) 1.14

Serum hemagglutination inhibition activity correlates with protection from gastroenteritis in persons infected with Norwalk virus. Clin Vaccine Immunol (2011) 1.10

Outbreak of small round structured virus gastroenteritis arose after kitchen assistant vomited. Commun Dis Rep CDR Rev (1997) 1.06

Antibody responses to norovirus genogroup GI.1 and GII.4 proteases in volunteers administered Norwalk virus. Clin Vaccine Immunol (2012) 0.97

Quantitative risk assessment: an emerging tool for emerging foodborne pathogens. Emerg Infect Dis (1997) 0.96

Comparison of norovirus RNA levels in outbreak-related oysters with background environmental levels. J Food Prot (2012) 0.91

Detection of norovirus in mouthwash samples from patients with acute gastroenteritis. J Clin Virol (2010) 0.82

Detection of norovirus infection in the hospital setting using vomit samples. J Clin Virol (2011) 0.82

Articles by these authors

Management of Helicobacter pylori infection--the Maastricht IV/ Florence Consensus Report. Gut (2012) 12.62

Traces of human migrations in Helicobacter pylori populations. Science (2003) 11.92

Norovirus gastroenteritis. N Engl J Med (2009) 7.66

Norwalk virus infection and disease is associated with ABO histo-blood group type. J Infect Dis (2002) 5.09

Laboratory efforts to cultivate noroviruses. J Gen Virol (2004) 4.41

Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG). Arch Virol (2011) 3.87

Norovirus vaccine against experimental human Norwalk Virus illness. N Engl J Med (2011) 3.78

Norwalk virus shedding after experimental human infection. Emerg Infect Dis (2008) 3.70

Obesity is an independent risk factor for GERD symptoms and erosive esophagitis. Am J Gastroenterol (2005) 3.34

Importance of Helicobacter pylori oipA in clinical presentation, gastric inflammation, and mucosal interleukin 8 production. Gastroenterology (2002) 3.27

Norwalk virus-like particle hemagglutination by binding to h histo-blood group antigens. J Virol (2003) 3.15

The peopling of the Pacific from a bacterial perspective. Science (2009) 3.14

Proton pump inhibitor use and recurrent Clostridium difficile-associated disease: a case-control analysis matched by propensity score. J Clin Gastroenterol (2012) 2.99

Gastroesophageal reflux among different racial groups in the United States. Gastroenterology (2004) 2.87

Norovirus disease: changing epidemiology and host susceptibility factors. Trends Microbiol (2004) 2.83

Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments. Arch Virol (2008) 2.77

Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood. Lancet (2002) 2.71

Adjuvanted intranasal Norwalk virus-like particle vaccine elicits antibodies and antibody-secreting cells that express homing receptors for mucosal and peripheral lymphoid tissues. J Infect Dis (2010) 2.64

Helicobacter pylori in North and South America before Columbus. FEBS Lett (2002) 2.57

Visible small-intestinal mucosal injury in chronic NSAID users. Clin Gastroenterol Hepatol (2005) 2.54

Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus. Proc Natl Acad Sci U S A (2008) 2.54

Rotavirus antigenaemia and viraemia: a common event? Lancet (2003) 2.51

The epidemiologic and clinical importance of norovirus infection. Gastroenterol Clin North Am (2006) 2.49

A report card to grade Helicobacter pylori therapy. Helicobacter (2007) 2.41

The 3' end of Norwalk virus mRNA contains determinants that regulate the expression and stability of the viral capsid protein VP1: a novel function for the VP2 protein. J Virol (2003) 2.38

Structural requirements for the assembly of Norwalk virus-like particles. J Virol (2002) 2.38

Norwalk virus infection associates with secretor status genotyped from sera. J Med Virol (2005) 2.34

Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1beta production in Helicobacter pylori infection. Gastroenterology (2002) 2.32

Serological correlate of protection against norovirus-induced gastroenteritis. J Infect Dis (2010) 2.21

Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection. Clin Gastroenterol Hepatol (2009) 2.15

X-ray structure of a native calicivirus: structural insights into antigenic diversity and host specificity. Proc Natl Acad Sci U S A (2006) 2.09

Rotaviruses: from pathogenesis to vaccination. Gastroenterology (2009) 2.05

Protective effect of natural rotavirus infection in an Indian birth cohort. N Engl J Med (2011) 2.04

Comparing the Blatchford and pre-endoscopic Rockall score in predicting the need for endoscopic therapy in patients with upper GI hemorrhage. Gastrointest Endosc (2010) 2.04

Duodenal ulcer promoting gene of Helicobacter pylori. Gastroenterology (2005) 2.03

Meta-analysis: four-drug, three-antibiotic, non-bismuth-containing "concomitant therapy" versus triple therapy for Helicobacter pylori eradication. Helicobacter (2009) 2.02

Effects of adjuvants on the safety and immunogenicity of an avian influenza H5N1 vaccine in adults. J Infect Dis (2008) 2.02

Optimal therapy for Helicobacter pylori infections. Nat Rev Gastroenterol Hepatol (2011) 1.98

Magnet ingestions in children presenting to US emergency departments, 2002-2011. J Pediatr Gastroenterol Nutr (2013) 1.98

Gastritis staging in clinical practice: the OLGA staging system. Gut (2006) 1.90

Complications of pediatric EGD: a 4-year experience in PEDS-CORI. Gastrointest Endosc (2007) 1.89

Humoral, mucosal, and cellular immune responses to oral Norwalk virus-like particles in volunteers. Clin Immunol (2003) 1.89

Immune responses of healthy subjects to a single dose of intramuscular inactivated influenza A/Vietnam/1203/2004 (H5N1) vaccine after priming with an antigenic variant. J Infect Dis (2008) 1.87

Neonatal infection with G10P[11] rotavirus did not confer protection against subsequent rotavirus infection in a community cohort in Vellore, South India. J Infect Dis (2007) 1.83

Immunogenicity and safety of varying dosages of a monovalent 2009 H1N1 influenza vaccine given with and without AS03 adjuvant system in healthy adults and older persons. J Infect Dis (2012) 1.80

Inter- and intragenus structural variations in caliciviruses and their functional implications. J Virol (2004) 1.79

Human caliciviruses in symptomatic and asymptomatic infections in children in Vellore, South India. J Med Virol (2007) 1.76

Risk factors for immediate and delayed bleeding associated with endoscopic submucosal dissection of gastric neoplastic lesions. Scand J Gastroenterol (2009) 1.75

NSAIDs, Helicobacter pylori, and Pandora's Box. N Engl J Med (2002) 1.75

Modified sequential Helicobacter pylori therapy: proton pump inhibitor and amoxicillin for 14 days with clarithromycin and metronidazole added as a quadruple (hybrid) therapy for the final 7 days. Helicobacter (2011) 1.73

Discrimination between cases of duodenal ulcer and gastritis on the basis of putative virulence factors of Helicobacter pylori. J Clin Microbiol (2002) 1.72

Evolutionary trace residues in noroviruses: importance in receptor binding, antigenicity, virion assembly, and strain diversity. J Virol (2005) 1.71

Patterns of gastric atrophy in intestinal type gastric carcinoma. Cancer (2002) 1.69

Biliary stenting in the management of large or multiple common bile duct stones. Gastrointest Endosc (2010) 1.68

Clinical and immunologic responses to multiple doses of IMVAMUNE (Modified Vaccinia Ankara) followed by Dryvax challenge. Vaccine (2007) 1.67

Norwalk virus RNA is infectious in mammalian cells. J Virol (2007) 1.66

Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature (2012) 1.65

Norwalk virus-specific binding to oyster digestive tissues. Emerg Infect Dis (2006) 1.63

Management of gastric polyps: a pathology-based guide for gastroenterologists. Nat Rev Gastroenterol Hepatol (2009) 1.62

The prevalence of suspected Barrett's esophagus in children and adolescents: a multicenter endoscopic study. Gastrointest Endosc (2006) 1.60

Role of interferon-stimulated responsive element-like element in interleukin-8 promoter in Helicobacter pylori infection. Gastroenterology (2004) 1.59

Helicobacter pylori infection in mice: Role of outer membrane proteins in colonization and inflammation. Gastroenterology (2002) 1.58

Iron deficiency and Helicobacter pylori infection in the United States. Am J Epidemiol (2005) 1.57

Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients. J Lipid Res (2002) 1.56

Replication and packaging of Norwalk virus RNA in cultured mammalian cells. Proc Natl Acad Sci U S A (2005) 1.56

Endoscopic demonstration of transient small bowel intussusception in a patient with adult celiac disease. Gastrointest Endosc (2003) 1.55

Identification of Genogroup I and Genogroup II broadly reactive epitopes on the norovirus capsid. J Virol (2005) 1.53

Structural analysis of histo-blood group antigen binding specificity in a norovirus GII.4 epidemic variant: implications for epochal evolution. J Virol (2011) 1.53

Comparative study of the epidemiology of rotavirus in children from a community-based birth cohort and a hospital in South India. J Clin Microbiol (2006) 1.51

Helicobacter pylori-negative gastritis: prevalence and risk factors. Am J Gastroenterol (2012) 1.51

Rising incidence of inflammatory bowel disease among children: a 12-year study. J Pediatr Gastroenterol Nutr (2010) 1.51

Quantitation of group A rotavirus by real-time reverse-transcription-polymerase chain reaction: correlation with clinical severity in children in South India. J Med Virol (2004) 1.50

Epidemiology of human noroviruses and updates on vaccine development. Curr Opin Gastroenterol (2014) 1.49

Rotavirus architecture at subnanometer resolution. J Virol (2008) 1.48

Safety and immunological outcomes following human inoculation with nontypeable Haemophilus influenzae. J Infect Dis (2013) 1.48