PubRank

Leonard R Johnson

Author PubWeight™ 41.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med 2004 1.86
2 STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells. Biochem J 2005 1.70
3 The lysophosphatidic acid type 2 receptor is required for protection against radiation-induced intestinal injury. Gastroenterology 2007 1.42
4 Lysophosphatidic acid protects and rescues intestinal epithelial cells from radiation- and chemotherapy-induced apoptosis. Gastroenterology 2002 1.23
5 Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1. Apoptosis 2011 1.09
6 MEK/ERK regulates adherens junctions and migration through Rac1. Cell Motil Cytoskeleton 2007 1.08
7 Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells. Cell Signal 2008 1.07
8 LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway. Am J Physiol Gastrointest Liver Physiol 2003 1.06
9 The requirement for polyamines for intestinal epithelial cell migration is mediated through Rac1. J Biol Chem 2003 1.05
10 TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species. Am J Physiol Gastrointest Liver Physiol 2008 1.05
11 Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-alpha in IEC-6 cells. Am J Physiol Gastrointest Liver Physiol 2003 1.04
12 Prevention of TNF-alpha-induced apoptosis in polyamine-depleted IEC-6 cells is mediated through the activation of ERK1/2. Am J Physiol Gastrointest Liver Physiol 2003 1.04
13 Rac1 mediates intestinal epithelial cell apoptosis via JNK. Am J Physiol Gastrointest Liver Physiol 2006 1.02
14 Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells. J Biol Chem 2005 1.00
15 Age-related susceptibility to apoptosis in human retinal pigment epithelial cells is triggered by disruption of p53-Mdm2 association. Invest Ophthalmol Vis Sci 2012 0.99
16 Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase. Biochem Biophys Res Commun 2004 0.95
17 Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor. J Biol Chem 2004 0.93
18 Integrin beta3-mediated Src activation regulates apoptosis in IEC-6 cells via Akt and STAT3. Biochem J 2006 0.92
19 Role of myosin regulatory light chain and Rac1 in the migration of polyamine-depleted intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2006 0.91
20 Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c. Am J Physiol Cell Physiol 2002 0.90
21 Polyamine depletion inhibits irradiation-induced apoptosis in intestinal epithelia. Am J Physiol Gastrointest Liver Physiol 2005 0.89
22 Amino acids regulate expression of antizyme-1 to modulate ornithine decarboxylase activity. J Biol Chem 2011 0.89
23 EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells. Cell Signal 2007 0.87
24 Regulation of JNK activity in the apoptotic response of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2011 0.87
25 The mechanism by which MEK/ERK regulates JNK and p38 activity in polyamine depleted IEC-6 cells during apoptosis. Apoptosis 2014 0.85
26 Polyamine-dependent activation of Rac1 is stimulated by focal adhesion-mediated Tiam1 activation. Cell Adh Migr 2010 0.85
27 Basic helix-loop-helix protein E47-mediated p21Waf1/Cip1 gene expression regulates apoptosis of intestinal epithelial cells. Biochem J 2007 0.84
28 Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid. Radiat Res 2015 0.82
29 RhoA inactivation inhibits cell migration but does not mediate the effects of polyamine depletion. Gastroenterology 2002 0.82
30 Spermine, a molecular switch regulating EGFR, integrin β3, Src, and FAK scaffolding. Cell Signal 2011 0.82
31 Polyamine-dependent migration of retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2002 0.82
32 MEK1 restores migration of polyamine-depleted cells by retention and activation of Rac1 in the cytoplasm. Am J Physiol Cell Physiol 2004 0.81
33 Spermidine, a sensor for antizyme 1 expression regulates intracellular polyamine homeostasis. Amino Acids 2014 0.81
34 Cyclin-dependent kinases regulate apoptosis of intestinal epithelial cells. Apoptosis 2014 0.80
35 RhoA stimulates IEC-6 cell proliferation by increasing polyamine-dependent Cdk2 activity. Am J Physiol Gastrointest Liver Physiol 2003 0.80
36 Antizyme (AZ) regulates intestinal cell growth independent of polyamines. Amino Acids 2014 0.79
37 Inhibition of Mdm2 sensitizes human retinal pigment epithelial cells to apoptosis. Invest Ophthalmol Vis Sci 2011 0.79
38 The role of PI 3-kinase in EGF-stimulated jejunal glucose transport. Can J Physiol Pharmacol 2002 0.79
39 The phosphorylation state of MRLC is polyamine dependent in intestinal epithelial cells. Am J Physiol Cell Physiol 2010 0.78
40 Regulation of intestinal mucosal growth by amino acids. Amino Acids 2013 0.78
41 Polyamines in cultured rabbit corneal cells. Invest Ophthalmol Vis Sci 2003 0.77
42 Immunocytochemical localization of polyamines during attachment and spreading of retinal pigment epithelial and intestinal epithelial cells. Cell Motil Cytoskeleton 2004 0.77
43 Effect of polyamine depletion on cone photoreceptors of the developing rabbit retina. Invest Ophthalmol Vis Sci 2002 0.75
44 Activation of Dbl restores migration in polyamine-depleted intestinal epithelial cells via Rho-GTPases. Am J Physiol Gastrointest Liver Physiol 2011 0.75