PubRank

Craig R Roy

Author PubWeight™ 113.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog 2006 5.17
2 The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol 2006 4.70
3 A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science 2002 4.49
4 Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites. Nat Cell Biol 2002 3.98
5 Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature 2007 3.81
6 Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science 2008 3.58
7 The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor. Nat Cell Biol 2006 3.08
8 A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells. Proc Natl Acad Sci U S A 2004 2.96
9 Modulation of host cell function by Legionella pneumophila type IV effectors. Annu Rev Cell Dev Biol 2010 2.92
10 Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J Exp Med 2004 2.67
11 Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature 2011 2.44
12 Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila. Infect Immun 2009 2.42
13 Effector proteins translocated by Legionella pneumophila: strength in numbers. Trends Microbiol 2007 2.42
14 Host cell processes that influence the intracellular survival of Legionella pneumophila. Cell Microbiol 2008 2.16
15 Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila. Proc Natl Acad Sci U S A 2013 2.05
16 The Legionella IcmS-IcmW protein complex is important for Dot/Icm-mediated protein translocation. Mol Microbiol 2005 1.89
17 Legionella reveal dendritic cell functions that facilitate selection of antigens for MHC class II presentation. Immunity 2003 1.85
18 Coxiella burnetii express type IV secretion system proteins that function similarly to components of the Legionella pneumophila Dot/Icm system. Mol Microbiol 2003 1.83
19 The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation. Science 2012 1.82
20 A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system. Mol Microbiol 2005 1.71
21 Show me the substrates: modulation of host cell function by type IV secretion systems. Cell Microbiol 2003 1.71
22 Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila. PLoS Pathog 2008 1.70
23 The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation. PLoS Pathog 2007 1.67
24 MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease. Infect Immun 2006 1.65
25 The Coxiella burnetii Dot/Icm system delivers a unique repertoire of type IV effectors into host cells and is required for intracellular replication. PLoS Pathog 2011 1.58
26 Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR. Nat Immunol 2013 1.46
27 NALP3: a key player in caspase-1 activation. J Endotoxin Res 2006 1.42
28 Inhibition of pathogen-induced apoptosis by a Coxiella burnetii type IV effector protein. Proc Natl Acad Sci U S A 2010 1.38
29 Coxiella burnetii inhibits activation of host cell apoptosis through a mechanism that involves preventing cytochrome c release from mitochondria. Infect Immun 2007 1.38
30 Attachment and fusion of endoplasmic reticulum with vacuoles containing Legionella pneumophila. Cell Microbiol 2006 1.37
31 Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. PLoS Pathog 2009 1.37
32 The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site. J Biol Chem 2004 1.33
33 Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems. Traffic 2006 1.21
34 Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole. PLoS One 2013 1.19
35 Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. J Biol Chem 2010 1.18
36 A Legionella pneumophila effector protein encoded in a region of genomic plasticity binds to Dot/Icm-modified vacuoles. PLoS Pathog 2009 1.17
37 Subversion of membrane transport pathways by vacuolar pathogens. J Cell Biol 2011 1.16
38 Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila. Infect Immun 2010 1.13
39 Host pathways important for Coxiella burnetii infection revealed by genome-wide RNA interference screening. MBio 2013 1.10
40 Modulation of ubiquitin dynamics and suppression of DALIS formation by the Legionella pneumophila Dot/Icm system. Cell Microbiol 2008 1.09
41 Legionella pneumophila promotes functional interactions between plasma membrane syntaxins and Sec22b. Traffic 2010 1.08
42 The Anaplasma phagocytophilum-occupied vacuole selectively recruits Rab-GTPases that are predominantly associated with recycling endosomes. Cell Microbiol 2010 1.07
43 Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell Microbiol 2011 1.07
44 A Rab-centric perspective of bacterial pathogen-occupied vacuoles. Cell Host Microbe 2013 1.05
45 Manipulation of host membrane machinery by bacterial pathogens. Curr Opin Cell Biol 2010 1.05
46 The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion. Cell Host Microbe 2012 1.03
47 Asc modulates the function of NLRC4 in response to infection of macrophages by Legionella pneumophila. MBio 2011 1.02
48 Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila. Cell Microbiol 2008 1.02
49 Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J Biol Chem 2004 1.02
50 Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain. EMBO J 2013 0.94
51 Legionella pneumophila subversion of host vesicular transport by SidC effector proteins. Traffic 2014 0.93
52 Autophagy and bacterial infection: an evolving arms race. Trends Microbiol 2013 0.92
53 NDP52: the missing link between ubiquitinated bacteria and autophagy. Nat Immunol 2009 0.92
54 The Coxiella burnetii Dot/Icm system creates a comfortable home through lysosomal renovation. MBio 2011 0.88
55 The role of Rab GTPases in the transport of vacuoles containing Legionella pneumophila and Coxiella burnetii. Biochem Soc Trans 2012 0.87
56 Cytosolic detection of flagellin: a deadly twist. Nat Immunol 2006 0.87
57 AMPylation is critical for Rab1 localization to vacuoles containing Legionella pneumophila. MBio 2014 0.87
58 Analysis of Rab1 recruitment to vacuoles containing Legionella pneumophila. Methods Enzymol 2005 0.86
59 The capping domain in RalF regulates effector functions. PLoS Pathog 2012 0.86
60 The Legionella pneumophila GTPase activating protein LepB accelerates Rab1 deactivation by a non-canonical hydrolytic mechanism. J Biol Chem 2013 0.86
61 A novel membrane sensor controls the localization and ArfGEF activity of bacterial RalF. PLoS Pathog 2013 0.86
62 Cellular hijacking: a common strategy for microbial infection. Trends Biochem Sci 2002 0.85
63 Activated macrophages infected with Legionella inhibit T cells by means of MyD88-dependent production of prostaglandins. J Immunol 2005 0.84
64 Immunity to vacuolar pathogens: what can we learn from Legionella? Cell Microbiol 2004 0.84
65 Inflammasome activation restricts Legionella pneumophila replication in primary microglial cells through flagellin detection. Glia 2013 0.82
66 Structure and function of interacting IcmR-IcmQ domains from a type IVb secretion system in Legionella pneumophila. Structure 2009 0.81
67 Processing and major histocompatibility complex class II presentation of Legionella pneumophila antigens by infected macrophages. Infect Immun 2005 0.80
68 Effect of vitrector cutting rate on vitreous biopsy yield. Retina 2005 0.77
69 Analyzing caspase-1 activation during Legionella pneumophila infection in macrophages. Methods Mol Biol 2013 0.76
70 Identification and functional characterization of K(+) transporters encoded by Legionella pneumophila kup genes. Cell Microbiol 2013 0.76
71 Trimming the fat: a Brucella abortus survival strategy. Nat Immunol 2005 0.76
72 Coxiella burnetii secretion systems. Adv Exp Med Biol 2012 0.76
73 Meeting report - Arf and Rab family G proteins. J Cell Sci 2013 0.76
74 Immunology: professional secrets. Nature 2003 0.75
75 Analyzing association of the endoplasmic reticulum with the legionella pneumophila-containing vacuoles by fluorescence microscopy. Methods Mol Biol 2008 0.75