Primary culture of parenchymal liver cells on collagen membranes. Morphological and biochemical observations.

PubWeight™: 3.87‹?› | Rank: Top 1%

🔗 View Article (PMID 243)

Published in Exp Cell Res on August 01, 1975

Authors

G Michalopoulos, H C Pitot

Articles citing this

(truncated to the top 100)

Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci (2003) 3.52

Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion. Proc Natl Acad Sci U S A (1985) 3.23

Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. Cold Spring Harb Symp Quant Biol (2005) 3.19

Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata. J Cell Biol (1984) 3.16

Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium. J Cell Biol (1996) 3.13

Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes. Proc Natl Acad Sci U S A (1977) 3.01

Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes. Mol Cell Biol (1983) 3.01

Tissue architecture: the ultimate regulator of breast epithelial function. Curr Opin Cell Biol (2003) 2.92

Extracellular matrix promotes mammary epithelial growth and differentiation in vitro. Proc Natl Acad Sci U S A (1982) 2.72

Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix. Proc Natl Acad Sci U S A (1984) 2.64

Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation. Semin Cancer Biol (2005) 2.53

Unraveling the microenvironmental influences on the normal mammary gland and breast cancer. Semin Cancer Biol (2008) 2.41

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc Natl Acad Sci U S A (1988) 2.30

Sustained growth and three-dimensional organization of primary mammary tumor epithelial cells embedded in collagen gels. Proc Natl Acad Sci U S A (1979) 2.15

The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology. Mol Cell Biol (1991) 2.11

Retrovirus-mediated transduction of adult hepatocytes. Proc Natl Acad Sci U S A (1988) 2.07

Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation. Proc Natl Acad Sci U S A (1979) 2.05

Autoregulation of tubulin synthesis in hepatocytes and fibroblasts. J Cell Biol (1985) 1.95

Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities. J Cell Biol (1985) 1.90

Connective tissue biomatrix: its isolation and utilization for long-term cultures of normal rat hepatocytes. J Cell Biol (1980) 1.84

Pulmonary surfactant and its components inhibit secretion of phosphatidylcholine from cultured rat alveolar type II cells. Proc Natl Acad Sci U S A (1987) 1.79

Posttranscriptional modulation of gene expression in cultured rat hepatocytes. Mol Cell Biol (1984) 1.75

Insulin induces calcium signals in the nucleus of rat hepatocytes. Hepatology (2008) 1.74

Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J (2008) 1.74

Collective movement of epithelial cells on a collagen gel substrate. Biophys J (2004) 1.70

Teratoma formation leads to failure of treatment for type I diabetes using embryonic stem cell-derived insulin-producing cells. Am J Pathol (2005) 1.69

Sustained growth in primary culture of normal mammary epithelial cells embedded in collagen gels. Proc Natl Acad Sci U S A (1980) 1.65

Human colon carcinoma cells use multiple receptors to adhere to laminin: involvement of alpha 6 beta 4 and alpha 2 beta 1 integrins. Cell Regul (1990) 1.55

Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase. Hepatology (2009) 1.54

Hepatocytes in collagen sandwich: evidence for transcriptional and translational regulation. J Cell Biol (1992) 1.53

Modulation of functional activities in cultured rat hepatocytes. Mol Cell Biochem (1983) 1.51

Organotypic liver culture models: meeting current challenges in toxicity testing. Crit Rev Toxicol (2012) 1.46

Fetal phenotypic expression by adult rat hepatocytes on collagen gel/nylon meshes. Proc Natl Acad Sci U S A (1979) 1.44

Dependence of hepatocyte-specific gene expression on cell-cell interactions in primary culture. EMBO J (1985) 1.44

Extraction and partial purification of a hepatic stimulatory substance in rats, mice, and dogs. Cancer Res (1987) 1.43

Liver cell models in in vitro toxicology. Environ Health Perspect (1998) 1.42

Growth state-dependent phenotypes of adult hepatocytes in primary monolayer culture. Proc Natl Acad Sci U S A (1978) 1.36

Cell surface distribution and intracellular fate of asialoglycoproteins: a morphological and biochemical study of isolated rat hepatocytes and monolayer cultures. J Cell Biol (1982) 1.35

Vectorial release of poliovirus from polarized human intestinal epithelial cells. J Virol (1993) 1.34

Effects of cyclic AMP, glucocorticoids and insulin on the activities of phosphatidate phosphohydrolase, tyrosine aminotransferase and glycerol kinase in isolated rat hepatocytes in relation to the control of triacylglycerol synthesis and gluconeogenesis. Biochem J (1985) 1.31

Screening for candidate hepatic growth factors by selective portal infusion after canine Eck's fistula. Hepatology (1991) 1.30

Structural cues from the tissue microenvironment are essential determinants of the human mammary epithelial cell phenotype. J Mammary Gland Biol Neoplasia (1998) 1.30

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer. Adv Drug Deliv Rev (2014) 1.25

Modulation of platelet-derived growth factor receptor expression in microvascular endothelial cells during in vitro angiogenesis. J Clin Invest (1994) 1.24

Macrophages express a plasma membrane receptor for basement membrane laminin. Am J Pathol (1986) 1.19

Kinase-independent transcriptional co-activation of peroxisome proliferator-activated receptor alpha by AMP-activated protein kinase. Biochem J (2004) 1.18

Accumulation of triacylglycerol in cultured rat hepatocytes is increased by ethanol and by insulin and dexamethasone. Biochem J (1983) 1.16

Expression of keratin and vimentin intermediate filaments in rabbit bladder epithelial cells at different stages of benzo[a]pyrene-induced neoplastic progression. J Cell Biol (1981) 1.16

Mouse mammary epithelial cells on floating collagen gels: transepithelial ion transport and effects of prolactin. Proc Natl Acad Sci U S A (1979) 1.14

Acquisition of antigens characteristic of adult pericentral hepatocytes by differentiating fetal hepatoblasts in vitro. J Cell Biol (1987) 1.10

Quantitative assay for albumin-producing liver cells after simian virus 40 transformation of rat hepatocytes maintained in chemically defined medium. Proc Natl Acad Sci U S A (1984) 1.08

Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata. J Cell Biol (1983) 1.07

Hepatocyte polarity. Compr Physiol (2013) 1.06

Lipogenesis and the synthesis and secretion of very low density lipoprotein by avian liver cells in nonproliferating monolayer culture. Hormonal effects. J Cell Biol (1977) 1.05

Growth and morphology of colonies of Chinese hamster ovary cells growing on agar is affected by insulin. Proc Natl Acad Sci U S A (1979) 1.04

Bidirectional entry of poliovirus into polarized epithelial cells. J Virol (1993) 1.04

Adhesive specificity of juvenile rat and chicken liver cells and membranes. Proc Natl Acad Sci U S A (1977) 1.03

Morphologic and histochemical analysis of hepatocytes transplanted into syngeneic hosts. Am J Pathol (1980) 1.03

Apical polarity in three-dimensional culture systems: where to now? J Biol (2010) 1.01

Three-dimensional cultures of mouse mammary epithelial cells. Methods Mol Biol (2013) 1.01

Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland. J Cell Biol (1981) 1.01

Epidermal growth factor and proliferation in rat hepatocytes in primary culture isolated at different times after partial hepatectomy. Cancer Res (1986) 1.00

Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver. J Cell Biol (1998) 1.00

Gene expression in the third dimension: the ECM-nucleus connection. J Mammary Gland Biol Neoplasia (2010) 0.99

The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell-ECM signaling. J Cell Biol (2011) 0.99

Glucose and triiodothyronine both induce malic enzyme in the rat hepatocyte culture: evidence that triiodothyronine multiplies a primary glucose-generated signal. J Clin Invest (1981) 0.98

Growth of normal mouse vaginal epithelial cells in and on collagen gels. Proc Natl Acad Sci U S A (1983) 0.98

Induction of peroxisomal beta-oxidation genes by retinoic acid in cultured rat hepatocytes. Biochem J (1992) 0.98

Cell types in rat liver cultures: their identification and isolation. Mol Cell Biochem (1983) 0.98

The tyrosine phosphorylation substrate p36 is developmentally regulated in embryonic avian limb and is induced in cell culture. J Cell Biol (1986) 0.98

Polarization of thyroid cells in culture: evidence for the basolateral localization of the iodide "pump" and of the thyroid-stimulating hormone receptor-adenyl cyclase complex. J Cell Biol (1983) 0.96

Macular corneal dystrophy. Studies of sulfated glycosaminoglycans in corneal explant and confluent stromal cell cultures. Am J Pathol (1977) 0.96

Induction and decay of glucagon-induced amino acid transport in primary cultures of adult rat liver cells: paradoxical effects of cycloheximide and puromycin. Proc Natl Acad Sci U S A (1976) 0.95

Signals and cells involved in regulating liver regeneration. Cells (2012) 0.94

A novel three-dimensional culture system of polarized epithelial cells to study endometrial carcinogenesis. Am J Pathol (2010) 0.92

The insulin receptor translocates to the nucleus to regulate cell proliferation in liver. Hepatology (2013) 0.92

Characterization of the Mr difference between secreted murine fourth component of complement and the major plasma form: evidence for carboxyl-terminal cleavage of the alpha chain. Proc Natl Acad Sci U S A (1982) 0.91

Regulation of functional cytodifferentiation and histogenesis in mammary epithelial cells: role of the extracellular matrix. Environ Health Perspect (1989) 0.89

Thyromimetic effect of peroxisomal proliferators in rat liver. Biochem J (1991) 0.88

Transformation of isolated rat hepatocytes with simian virus 40. J Cell Biol (1980) 0.88

An improved collagen scaffold for skeletal regeneration. J Biomed Mater Res A (2010) 0.88

Prevention of peroxisomal proliferation by carnitine palmitoyltransferase inhibitors in cultured rat hepatocytes and in vivo. Biochem J (1987) 0.87

The intracellular triacylglycerol/fatty acid cycle: a comparison of its activity in hepatocytes which secrete exclusively apolipoprotein (apo) B100 very-low-density lipoprotein (VLDL) and in those which secrete predominantly apoB48 VLDL. Biochem J (1998) 0.85

Increase of L-serine dehydratase activity under gluconeogenic conditions in adult-rat hepatocytes cultured on collagen gel/nylon mesh. Biochem J (1981) 0.84

Effect of ethanol on lipid metabolism in cultured hepatocytes. Biochem J (1985) 0.82

Induction of peroxisome proliferation in hepatocytes transplanted into the anterior chamber of the eye. A model system for the evaluation of xenobiotic-induced effects. Am J Pathol (1986) 0.80

Isolation and culture of intrahepatic bile ducts and its application in assessing putative inducers of biliary epithelial cell hyperplasia. Br J Exp Pathol (1987) 0.80

Plasma protein induction by isolated hepatocytes. Mol Cell Biochem (1983) 0.80

Influence of collagen substrata on glycosaminoglycan production by B16 melanoma cells. Proc Natl Acad Sci U S A (1983) 0.80

The origins of the molecular era of adhesion research. Nat Rev Mol Cell Biol (2012) 0.79

Interaction of chemical carcinogens and drug-metabolizing enzymes in primary cultures of hepatic cells from the rat. Am J Pathol (1976) 0.79

Challenges in using cultured primary rodent hepatocytes or cell lines to study hepatic HDL receptor SR-BI regulation by its cytoplasmic adaptor PDZK1. PLoS One (2013) 0.79

Organoids: A historical perspective of thinking in three dimensions. J Cell Biol (2016) 0.78

Decreased secretion of very-low-density lipoprotein triacylglycerol and apolipoprotein B is associated with decreased intracellular triacylglycerol lipolysis in hepatocytes derived from rats fed orotic acid or n-3 fatty acids. Biochem J (1997) 0.78

Effect of Tissue-Culture Substratum and Extracellular Matrix Overlay on Liver-Selective and Xenobiotic Inducible Gene Expression in Primary Rat Hepatocytes. In Vitro Toxicol (1994) 0.78

Efficient expansion of mouse primary tenocytes using a novel collagen gel culture method. Histochem Cell Biol (2014) 0.77

Architecture Is the Message: The role of extracellular matrix and 3-D structure in tissue-specific gene expression and breast cancer. Pezcoller Found J (2007) 0.77

Development of intrahepatic bile ducts in rat foetal liver explants in vitro. J Exp Pathol (Oxford) (1990) 0.75

Of plasticity and specificity: dialectics of the micro- and macro-environment and the organ phenotype. Wiley Interdiscip Rev Membr Transp Signal (2014) 0.75

Enhanced melanogenesis of murine melanoma cells cultured on or in collagen gel. Arch Dermatol Res (1990) 0.75

Articles by these authors

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science (1990) 9.90

Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients. Circulation (1993) 3.29

Effects of the antiestrogens tamoxifen, toremifene, and ICI 182,780 on endometrial cancer growth. J Natl Cancer Inst (1998) 2.88

Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes. Cancer Res (1989) 2.59

Use of a low-speed, iso-density percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations. In Vitro Cell Dev Biol (1986) 2.26

Control of hepatocyte replication by two serum factors. Cancer Res (1984) 2.20

MCM7 amplification and overexpression are associated with prostate cancer progression. Oncogene (2006) 2.07

The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals. J Virol (1999) 2.01

Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE. Biochem Biophys Res Commun (1991) 1.95

The stages of initiation and promotion in hepatocarcinogenesis. Biochim Biophys Acta (1980) 1.94

Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer. Clin Cancer Res (2000) 1.81

Liver regeneration studies with rat hepatocytes in primary culture. Cancer Res (1982) 1.81

Gamma-glutamyl transpeptidase--its role in hepatocarcinogenesis. Carcinogenesis (1985) 1.68

Biochemical characterisation of stages of hepatocarcinogenesis after a single dose of diethylnitrosamine. Nature (1978) 1.67

Quantitative evaluation of the promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin of hepatocarcinogenesis from diethylnitrosamine. Cancer Res (1980) 1.61

Phase I study of the matrix metalloproteinase inhibitor, BAY 12-9566. Ann Oncol (2001) 1.52

Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro. Hepatology (1994) 1.49

Feedback control of rat liver tryptophan pyrrolase. I. End product inhibition of trytophan pyrrolase activity. J Biol Chem (1967) 1.49

Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice. Proc Natl Acad Sci U S A (1993) 1.48

Sequence of the precursor to rat ornithine aminotransferase deduced from a cDNA clone. J Biol Chem (1985) 1.46

Fetal phenotypic expression by adult rat hepatocytes on collagen gel/nylon meshes. Proc Natl Acad Sci U S A (1979) 1.44

Transcriptional regulation of c-myc during chemically induced differentiation of HL-60 cultures. Cancer Res (1985) 1.44

Polyribosomal attachment to rat liver and hepatoma endoplasmic reticulum in vitro. A method for its study. Biochem J (1971) 1.43

Tissue distribution of hepatopoietin-A: a heparin-binding polypeptide growth factor for hepatocytes. Proc Natl Acad Sci U S A (1990) 1.41

Acetylation of nascent polypeptide chains on rat liver polyribosomes in vivo and in vitro. Biochemistry (1975) 1.41

Application of quantitative stereology to the evaluation of enzyme-altered foci in rat liver. Cancer Res (1982) 1.35

Variation of hepatic malic enzyme capacity with hepatoma susceptibility in mice of different genotypes. Cancer Res (1972) 1.34

Improved assay of 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Lipid Res (1971) 1.30

The effect of human C apolipoproteins on the in vitro hepatic metabolism of triglyceride emulsions in the rat. J Biol Chem (1982) 1.29

Influence of background genome on enzymatic characteristics of yellow (A v -, A vy -) mice. Genetics (1973) 1.29

Collagen as a substrate for cell growth and differentiation. Methods Enzymol (1982) 1.28

Alpha 1-adrenergic effects and liver regeneration. Hepatology (1988) 1.25

Transplantation system for determining the clonogenic survival of parenchymal hepatocytes exposed to ionizing radiation. Cancer Res (1981) 1.22

Isolation and nucleotide sequence of the cDNA for rat liver serine dehydratase mRNA and structures of the 5' and 3' flanking regions of the serine dehydratase gene. Proc Natl Acad Sci U S A (1988) 1.22

Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type I ductular reaction in mice: interactions between the periductal inflammatory and stromal cells and the biliary epithelium. Hepatology (1998) 1.20

Characterization of ductular hepatocytes in end-stage cirrhosis. Arch Pathol Lab Med (1990) 1.20

Phase I trial of temozolomide (NSC 362856) in patients with advanced cancer. Clin Cancer Res (1997) 1.19

Neutral glycolipids of migrating and nonmigrating rabbit corneal epithelium in organ and cell culture. Invest Ophthalmol Vis Sci (1990) 1.19

Studies on the induction and repression of enzymes in rat liver. V. Regulation of the rate of synthesis and degradation of serine dehydratase by dietary amino acids and glucose. J Biol Chem (1968) 1.18

Structure and function of rat liver polysome populations. I. Complexity, frequency distribution, and degree of uniqueness of free and membrane-bound polysomal polyadenylate-containing RNA populations. J Cell Biol (1981) 1.17

Isolation and fractionation of ribonucleic acid from the smooth endoplasmic reticulum of rat liver. Biochim Biophys Acta (1966) 1.17

The association in vitro of polyribosomes with ribonuclease-treated derivatives of hepatic rough endoplasmic reticulum. Characteristics of the membrane binding sites and factors influencing association. Biochem J (1971) 1.16

Ultrastructure of adult rat hepatocytes cultured on floating collagen membranes. Cancer Res (1978) 1.14

Rat liver and hepatoma polysome-membrane interaction in vitro. Biochem Biophys Res Commun (1966) 1.13

Localization of polysome-bound albumin and serine dehydratase in rat liver cell fractions. J Cell Biol (1973) 1.12

Isolation, culture, and transplantation of human hepatocytes. J Natl Cancer Inst (1982) 1.12

Reestablishment of cell polarity of rat hepatocytes in primary culture. Hepatology (1993) 1.10

Systematic oscillations in metabolic activity in rat liver and in hepatomas. I. Morris hepatoma No. 7793. Cancer Res (1966) 1.10

Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes. Nature (1982) 1.10

Ductular reaction after submassive necrosis in humans. Special emphasis on analysis of ductular hepatocytes. Am J Pathol (1996) 1.10

3',5'-Cyclic AMP and the release of polysome-bound proteins in vitro. Biochem Biophys Res Commun (1967) 1.08

Response of hepatic enzyme activities to castration and sarcoma 37 growth in different mouse genotypes. J Natl Cancer Inst (1972) 1.08

Binding of alpha 2-macroglobulin to hepatocytes: mechanism of in vivo clearance. Biochem Biophys Res Commun (1985) 1.07

Phenobarbital-inducible aldehyde dehydrogenase in the rat. cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats. J Biol Chem (1989) 1.07

Molecular cloning, sequence analysis, and expression in Escherichia coli of the cDNA for guanidinoacetate methyltransferase from rat liver. Proc Natl Acad Sci U S A (1988) 1.06

Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine. J Biol Chem (1973) 1.06

Myopodin, a synaptopodin homologue, is frequently deleted in invasive prostate cancers. Am J Pathol (2001) 1.06

Drug metabolism and effects of carcinogens in cultured hepatic cells. Pharmacol Rev (1979) 1.05

Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver. J Cell Sci (1994) 1.04

Multiple cell cycles occur in rat hepatocytes cultured in the presence of nicotinamide and epidermal growth factor. Hepatology (1991) 1.04

NH2-terminal amino acid sequence of rabbit hepatopoietin A, a heparin-binding polypeptide growth factor for hepatocytes. Biochem Biophys Res Commun (1989) 1.04

Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling. BMC Bioinformatics (2005) 1.04

Enzyme levels in rats adapted to 36-hour fasting. Adv Enzyme Regul (1966) 1.04

Hormonal regulation and the effects of glucose on tyrosine aminotransferase activity in adult rat hepatocytes cultured on floating collagen membranes. Cancer Res (1978) 1.03

Morphologic and histochemical analysis of hepatocytes transplanted into syngeneic hosts. Am J Pathol (1980) 1.03

Treatment of neuroendocrine cancer metastatic to the liver: the role of ablative techniques. Cardiovasc Intervent Radiol (2005) 1.03

Systematic oscillations in tyrosine transaminase and other metabolic functions in liver of normal and adrenalectomized rats on controlled feeding schedules. J Nutr (1968) 1.02

Preoperative hepatic artery chemoembolization followed by orthotopic liver transplantation for hepatocellular carcinoma. Liver Transpl Surg (1999) 1.02

The automated assay of complete enzyme reaction rates. II. Digital readout and data processing of linear rates. Anal Biochem (1968) 1.02

Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas. J Neurosci (1994) 1.02

Cytochrome P-450 induction by phenobarbital and 3-methylcholanthrene in primary cultures of hepatocytes. Science (1976) 1.02

Quantitative analysis of the time-dependent development of glucose-6-phosphatase-deficient foci in the livers of mice treated neonatally with diethylnitrosamine. Cancer Res (1981) 1.02

Human gamma-glutamyl transpeptidase cDNA: comparison of hepatoma and kidney mRNA in the human and rat. Gene (1989) 1.01

Hormonal regulation of glucokinase in primary cultures of adult rat hepatocytes. J Biol Chem (1979) 1.01

Template stability of some enzymes in rat liver and hepatoma. Proc Natl Acad Sci U S A (1965) 1.00

Phase I and pharmacokinetic study of irinotecan and docetaxel in patients with advanced solid tumors: preliminary evidence of clinical activity. J Clin Oncol (2000) 1.00

Glucose repression and induction of enzyme synthesis in rat liver. Adv Enzyme Regul (1964) 1.00

Polyamine degradation in foetal and adult bovine serum. Biochem J (1982) 0.99

Control mechanisms in the normal and neoplastic cell. Prog Exp Tumor Res (1965) 0.99

Polysome interaction in vitro with microsomal membranes from rat liver. Biochem Biophys Res Commun (1971) 0.99

Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7. Gene Ther (1997) 0.99

Studies on the induction and repression of enzymes in rat liver. VI. Some properties and the metabolic regulation of two isozymic forms of serine dehydratase. J Biol Chem (1971) 0.99

Identification and partial characterization of receptor binding sites for HGF on rat hepatocytes. Biochem Biophys Res Commun (1990) 0.98

Dietary induction of some enzymes of amino acid metabolism during 2-acetylaminofluorene feeding. Cancer Res (1969) 0.98

The role of the stages of initiation and promotion in phenotypic diversity during hepatocarcinogenesis in the rat. Carcinogenesis (1992) 0.97

Induction of lipogenic enzymes in primary cultures of rat hepatocytes. Relationship between lipogenesis and carbohydrate metabolism. Eur J Biochem (1982) 0.97

Transcriptional control of ornithine aminotransferase synthesis in rat kidney by estrogen and thyroid hormone. J Biol Chem (1984) 0.97

Diurnal variation of the serine dehydratase mRNA level in rat liver. Arch Biochem Biophys (1994) 0.97

Repair of radiation damage in noncycling parenchymal hepatocytes. Br J Radiol (1982) 0.96

Characterization and sequence of a cDNA clone of gamma-glutamyltranspeptidase. Nucleic Acids Res (1986) 0.96

Modulation of c-myc expression in the HL-60 cell line. Biochem Biophys Res Commun (1984) 0.96

Direct association of messenger RNA labeled in the presence of fluoroorotate with membranes of the endoplasmic reticulum in rat liver. J Cell Biol (1976) 0.95

Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine. Cancer Res (1974) 0.95

Effects of extracellular matrix components on the growth and differentiation of cultured rat hepatocytes. In Vitro Cell Dev Biol (1987) 0.95

Exocrine pancreatic tissue in human liver: a metaplastic process? Am J Surg Pathol (1990) 0.95

Methodology and utility of primary cultures of hepatocytes from experimental animals. Methods Cell Biol (1980) 0.95

Preparation of ribonuclease-free DNase I and -amylase. Anal Biochem (1973) 0.95