Simultaneous microdetermination of bosentan, ambrisentan, sildenafil, and tadalafil in plasma using liquid chromatography/tandem mass spectrometry for pediatric patients with pulmonary arterial hypertension.

PubWeight™: 0.83^‹?›

🔗 View Article (PMID 24309556)

Published in J Pharm Biomed Anal on November 15, 2013

Authors

Yoshinari Yokoyama¹, Miho Tomatsuri¹, Hideki Hayashi¹, Keita Hirai², Yasuo Ono³, Yuto Yamada¹, Kenichiro Todoroki⁴, Toshimasa Toyo'oka⁴, Hiroshi Yamada⁵, Kunihiko Itoh⁶

Author Affiliations

1: Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
2: Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan; Department of Pharmacy, Shizuoka Children's Hospital, 860, Urushiyama, Aoi-ku, Shizuoka, Japan.
3: Department of Pediatric Cardiology, Shizuoka Children's Hospital, 860, Urushiyama, Aoi-ku, Shizuoka, Japan.
4: Department of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
5: Department of Drug Evaluation & Informatics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
6: Department of Clinical Pharmacology and Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan. Electronic address: itohk@u-shizuoka-ken.ac.jp.

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