Irwin J Kurland

Author PubWeight™ 25.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J 2011 2.36
2 NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism. Nat Med 2006 2.15
3 Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Cell Metab 2012 1.64
4 Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1. J Clin Invest 2012 1.52
5 SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase. Mol Cell 2013 1.52
6 Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn. Cell Metab 2007 1.34
7 Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production. J Biol Chem 2002 1.29
8 Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux. Endocrinology 2003 1.25
9 Lipin deficiency impairs diurnal metabolic fuel switching. Diabetes 2006 1.19
10 The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching. J Proteome Res 2011 1.17
11 Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1. Cell Metab 2010 1.12
12 Determination of a glucose-dependent futile recycling rate constant from an intraperitoneal glucose tolerance test. Anal Biochem 2003 1.07
13 Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse. Diabetes 2006 1.01
14 Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice. J Biol Chem 2008 0.97
15 Enhanced energy expenditure, glucose utilization, and insulin sensitivity in VAMP8 null mice. Diabetes 2010 0.93
16 Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins. J Lipid Res 2014 0.91
17 Role of endosomal trafficking dynamics on the regulation of hepatic insulin receptor activity: models for Fao cells. Ann Biomed Eng 2006 0.90
18 Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation. PLoS One 2012 0.87
19 Advantages of dynamic "closed loop" stable isotope flux phenotyping over static "open loop" clamps in detecting silent genetic and dietary phenotypes. Metabolomics 2009 0.84
20 Advantages of tandem LC-MS for the rapid assessment of tissue-specific metabolic complexity using a pentafluorophenylpropyl stationary phase. J Proteome Res 2011 0.80
21 Alteration of de novo glucose production contributes to fasting hypoglycaemia in Fyn deficient mice. PLoS One 2013 0.76
22 UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J 2016 0.75
23 Lower mitochondrial DNA and altered mitochondrial fuel metabolism in hiv-exposed uninfected infants in cameroon. AIDS 2017 0.75