PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.

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🔗 View Article (PMID 24316071)

Published in Cell Rep on December 05, 2013

Authors

Joshua M Horne-Debets1, Rebecca Faleiro1, Deshapriya S Karunarathne1, Xue Q Liu2, Katie E Lineburg1, Chek Meng Poh3, Gijsbert M Grotenbreg4, Geoffrey R Hill1, Kelli P A MacDonald1, Michael F Good2, Laurent Renia3, Rafi Ahmed5, Arlene H Sharpe6, Michelle N Wykes7

Author Affiliations

1: QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD 4029, Australia.
2: QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD 4029, Australia; Institute for Glycomics, Griffith University, Gold Coast Campus, QLD 4222, Australia.
3: Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), Singapore 136648, Singapore; Department of Microbiology, Life Sciences Institute, National University of Singapore, Singapore 117597, Singapore.
4: Department of Microbiology, Life Sciences Institute, National University of Singapore, Singapore 117597, Singapore; Department of Biological Sciences, Faculty of Science, Life Sciences Institute, National University of Singapore, Singapore, Singapore 117597, Singapore; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore 117597, Singapore.
5: Emory Vaccine Center, 954 Gatewood Road, Atlanta, GA 30329, USA.
6: Harvard Medical School, Department of Microbiology and Immunobiology, Boston, MA 02115, USA.
7: QIMR Berghofer Medical Research Institute, 300 Herston Road, Brisbane, QLD 4029, Australia. Electronic address: michelle.wykes@qimrberghofer.edu.au.

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