PubRank

Raymond A Swanson

Author PubWeight™ 87.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Astrocytes and brain injury. J Cereb Blood Flow Metab 2003 3.13
2 NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation. Nat Neurosci 2009 2.71
3 Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase. J Clin Invest 2007 2.43
4 NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J Neurosci 2010 2.41
5 Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat Neurosci 2005 2.31
6 Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition. J Biol Chem 2004 2.21
7 Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. Proc Natl Acad Sci U S A 2006 2.07
8 P2X7 receptor-mediated release of excitatory amino acids from astrocytes. J Neurosci 2003 1.94
9 Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. Ann Neurol 2008 1.86
10 Microglial activation in stroke: therapeutic targets. Neurotherapeutics 2010 1.84
11 Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. Proc Natl Acad Sci U S A 2006 1.68
12 Poly(ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death. J Immunol 2005 1.68
13 ATP-induced ATP release from astrocytes. J Neurochem 2004 1.64
14 Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia. J Neurosci 2003 1.49
15 NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem Biophys Res Commun 2003 1.46
16 Hypoglycemia, brain energetics, and hypoglycemic neuronal death. Glia 2007 1.41
17 Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with the glycogen phosphorylase inhibitor CP-316,819 ([R-R*,S*]-5-chloro-N-[2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide). J Pharmacol Exp Ther 2007 1.38
18 NAD+ as a metabolic link between DNA damage and cell death. J Neurosci Res 2004 1.36
19 The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures. J Neurochem 2003 1.32
20 Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor. J Neuroinflammation 2012 1.22
21 Differences among cell types in NAD(+) compartmentalization: a comparison of neurons, astrocytes, and cardiac myocytes. J Neurosci Res 2007 1.22
22 Zinc triggers microglial activation. J Neurosci 2008 1.20
23 Pyruvate administered after severe hypoglycemia reduces neuronal death and cognitive impairment. Diabetes 2005 1.20
24 Alternative, nonapoptotic programmed cell death: mediation by arrestin 2, ERK2, and Nur77. J Biol Chem 2004 1.19
25 Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. J Cereb Blood Flow Metab 2002 1.17
26 Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion. Stroke 2007 1.16
27 Overexpression of rat heat shock protein 70 is associated with reduction of early mitochondrial cytochrome C release and subsequent DNA fragmentation after permanent focal ischemia. J Cereb Blood Flow Metab 2003 1.14
28 N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse. Ann Neurol 2010 1.14
29 Zinc release contributes to hypoglycemia-induced neuronal death. Neurobiol Dis 2004 1.12
30 Novel modulators of poly(ADP-ribose) polymerase. Trends Pharmacol Sci 2006 1.12
31 Inhibition of mitochondrial function in astrocytes: implications for neuroprotection. J Neurochem 2007 1.12
32 Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury. J Cereb Blood Flow Metab 2009 1.12
33 Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production. Ann Neurol 2011 1.11
34 Ischemia-induced programmed cell death in astrocytes. Glia 2005 1.11
35 Poly(ADP-ribose) polymerase-1 hyperactivation and impairment of mitochondrial respiratory chain complex I function in reperfused mouse hearts. Am J Physiol Heart Circ Physiol 2006 1.10
36 Sequential release of nitric oxide, zinc, and superoxide in hypoglycemic neuronal death. J Cereb Blood Flow Metab 2008 1.09
37 Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte death. J Cereb Blood Flow Metab 2005 1.09
38 Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1. J Neurosci 2003 1.06
39 Pyruvate protects against experimental stroke via an anti-inflammatory mechanism. Neurobiol Dis 2009 1.05
40 Activation of neuronal NMDA receptors induces superoxide-mediated oxidative stress in neighboring neurons and astrocytes. J Neurosci 2012 1.04
41 Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab 2006 1.01
42 Overexpression of rat heat shock protein 70 reduces neuronal injury after transient focal ischemia, transient global ischemia, or kainic acid-induced seizures. Neurosurgery 2003 1.01
43 Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN gamma kinase activation leading to cytoskeleton function and cell migration in astrocytes. J Neurochem 2007 0.99
44 Human serum albumin and its N-terminal tetrapeptide (DAHK) block oxidant-induced neuronal death. Stroke 2004 0.95
45 Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression. J Neurosci 2011 0.95
46 Cerebral ischemia and infarction from atheroemboli <100 microm in Size. Stroke 2003 0.95
47 Intracellular pH reduction prevents excitotoxic and ischemic neuronal death by inhibiting NADPH oxidase. Proc Natl Acad Sci U S A 2013 0.92
48 Poly(ADP-ribose) polymerase-1 activation in a primate model of multiple sclerosis. J Neurosci Res 2005 0.91
49 Players in the PARP-1 cell-death pathway: JNK1 joins the cast. Trends Biochem Sci 2006 0.91
50 EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia. J Neurosci 2010 0.91
51 Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation. Biochim Biophys Acta 2013 0.90
52 Zinc inhibits astrocyte glutamate uptake by activation of poly(ADP-ribose) polymerase-1. Mol Med 2007 0.89
53 Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β. J Neuroinflammation 2011 0.89
54 Hypoglycemia induces transient neurogenesis and subsequent progenitor cell loss in the rat hippocampus. Diabetes 2005 0.89
55 Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotide. J Neurotrauma 2012 0.88
56 Expression and activity of poly(ADP-ribose) glycohydrolase in cultured astrocytes, neurons, and C6 glioma cells. Brain Res Mol Brain Res 2003 0.88
57 Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats. J Neuroinflammation 2012 0.87
58 Astrocyte cultures exhibit P2X7 receptor channel opening in the absence of exogenous ligands. Glia 2009 0.86
59 Barbiturates induce mitochondrial depolarization and potentiate excitotoxic neuronal death. J Neurosci 2002 0.85
60 Sirtuins in neurodegenerative diseases: an update on potential mechanisms. Front Aging Neurosci 2013 0.85
61 A systematic survey of lipids across mouse tissues. Am J Physiol Endocrinol Metab 2014 0.84
62 NADH can enter into astrocytes and block poly(ADP-ribose) polymerase-1-mediated astrocyte death. Neuroreport 2005 0.83
63 Beneficial effects of minocycline and botulinum toxin-induced constraint physical therapy following experimental traumatic brain injury. Neurorehabil Neural Repair 2013 0.83
64 Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity. Glia 2010 0.82
65 Mitochondrial dysfunction induced by nuclear poly(ADP-ribose) polymerase-1: a treatable cause of cell death in stroke. Transl Stroke Res 2013 0.82
66 Selective down-regulation of nuclear poly(ADP-ribose) glycohydrolase. PLoS One 2009 0.82
67 Extracellular conversion of guanine-based purines to guanosine specifically enhances astrocyte glutamate uptake. Brain Res 2003 0.80
68 NADPH oxidase-2: linking glucose, acidosis, and excitotoxicity in stroke. Antioxid Redox Signal 2015 0.80
69 Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices. J Bioenerg Biomembr 2004 0.78
70 Intracerebral hematoma: beyond the mass lesion. Stroke 2006 0.78
71 Hypoxia induces caspase-9 and caspase-3 activation without neuronal death in gerbil brains. Eur J Neurosci 2004 0.78
72 Vitamin B12 deficiency. Arch Neurol 2004 0.76
73 One cell's poison is another cell's cure. Nat Neurosci 2012 0.75
74 INTRODUCTION: Immune mechanisms of neurodegeneration. Clin Neurosci Res 2006 0.75