|
1
|
Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs.
|
Cell Cycle
|
2011
|
1.80
|
|
2
|
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
|
Nucleic Acids Res
|
2009
|
1.29
|
|
3
|
Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo.
|
PLoS One
|
2010
|
1.10
|
|
4
|
New self-assembly nanoparticles and stealth liposomes for the delivery of zoledronic acid: a comparative study.
|
Biotechnol Adv
|
2011
|
1.09
|
|
5
|
Evaluation of the in vitro and in vivo antiangiogenic effects of denosumab and zoledronic acid.
|
Cancer Biol Ther
|
2012
|
0.93
|
|
6
|
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
|
Nucleic Acids Res
|
2013
|
0.90
|
|
7
|
A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells.
|
J Exp Clin Cancer Res
|
2013
|
0.89
|
|
8
|
DNA damage persistence as determinant of tumor sensitivity to the combination of Topo I inhibitors and telomere-targeting agents.
|
Clin Cancer Res
|
2011
|
0.88
|
|
9
|
N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage.
|
J Med Chem
|
2011
|
0.84
|
|
10
|
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
|
J Exp Clin Cancer Res
|
2013
|
0.83
|
|
11
|
A new avenue toward androgen receptor pan-antagonists: C2 sterically hindered substitution of hydroxy-propanamides.
|
J Med Chem
|
2014
|
0.80
|
|
12
|
Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan.
|
Int J Oncol
|
2013
|
0.80
|
|
13
|
Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells.
|
ChemMedChem
|
2012
|
0.77
|
|
14
|
Human placenta-derived neurospheres are susceptible to transformation after extensive in vitro expansion.
|
Stem Cell Res Ther
|
2014
|
0.75
|
|
15
|
Effect of small molecules modulating androgen receptor (SARMs) in human prostate cancer models.
|
PLoS One
|
2013
|
0.75
|