| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Murine models of pulmonary fibrosis.
|
Am J Physiol Lung Cell Mol Physiol
|
2007
|
5.92
|
|
2
|
Epigenetic regulation of the alternatively activated macrophage phenotype.
|
Blood
|
2009
|
3.76
|
|
3
|
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events.
|
J Exp Med
|
2008
|
3.62
|
|
4
|
Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10).
|
Am J Respir Crit Care Med
|
2005
|
2.86
|
|
5
|
The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth.
|
Blood
|
2010
|
1.97
|
|
6
|
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction.
|
Nat Biotechnol
|
2011
|
1.91
|
|
7
|
A micro RNA processing defect in rapidly progressing idiopathic pulmonary fibrosis.
|
PLoS One
|
2011
|
1.87
|
|
8
|
TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.
|
Int J Biochem Cell Biol
|
2010
|
1.79
|
|
9
|
PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis.
|
Am J Physiol Lung Cell Mol Physiol
|
2007
|
1.74
|
|
10
|
Infectious disease, the innate immune response, and fibrosis.
|
J Clin Invest
|
2007
|
1.68
|
|
11
|
Epigenetic regulation of dendritic cell-derived interleukin-12 facilitates immunosuppression after a severe innate immune response.
|
Blood
|
2007
|
1.64
|
|
12
|
The chronic consequences of severe sepsis.
|
J Leukoc Biol
|
2003
|
1.62
|
|
13
|
Serum amyloid P therapeutically attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages.
|
PLoS One
|
2010
|
1.59
|
|
14
|
Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia.
|
Am J Respir Crit Care Med
|
2004
|
1.59
|
|
15
|
Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
|
Am J Respir Crit Care Med
|
2014
|
1.54
|
|
16
|
Reversal of long-term sepsis-induced immunosuppression by dendritic cells.
|
Blood
|
2004
|
1.44
|
|
17
|
CCR7 impairs hematopoiesis after hematopoietic stem cell transplantation increasing susceptibility to invasive aspergillosis.
|
Blood
|
2010
|
1.44
|
|
18
|
TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4.
|
J Clin Invest
|
2008
|
1.43
|
|
19
|
Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.
|
FASEB J
|
2009
|
1.41
|
|
20
|
Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2.
|
Int J Biochem Cell Biol
|
2008
|
1.36
|
|
21
|
Immunomodulatory role of CXCR2 during experimental septic peritonitis.
|
J Immunol
|
2003
|
1.36
|
|
22
|
Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.
|
Am J Pathol
|
2002
|
1.34
|
|
23
|
A systemic granulomatous response to Schistosoma mansoni eggs alters responsiveness of bone-marrow-derived macrophages to Toll-like receptor agonists.
|
J Leukoc Biol
|
2007
|
1.33
|
|
24
|
Animal models of fibrotic lung disease.
|
Am J Respir Cell Mol Biol
|
2013
|
1.31
|
|
25
|
Variable prostaglandin E2 resistance in fibroblasts from patients with usual interstitial pneumonia.
|
Am J Respir Crit Care Med
|
2007
|
1.29
|
|
26
|
Therapeutic attenuation of pulmonary fibrosis via targeting of IL-4- and IL-13-responsive cells.
|
J Immunol
|
2003
|
1.27
|
|
27
|
The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice.
|
J Clin Invest
|
2010
|
1.27
|
|
28
|
Septic mice are susceptible to pulmonary aspergillosis.
|
Am J Pathol
|
2003
|
1.25
|
|
29
|
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
|
Am J Pathol
|
2008
|
1.24
|
|
30
|
Chemokines provide the sustained inflammatory bridge between innate and acquired immunity.
|
Cytokine Growth Factor Rev
|
2005
|
1.23
|
|
31
|
Hypermethylation of PTGER2 confers prostaglandin E2 resistance in fibrotic fibroblasts from humans and mice.
|
Am J Pathol
|
2010
|
1.23
|
|
32
|
MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4.
|
J Leukoc Biol
|
2005
|
1.22
|
|
33
|
Serum amyloid P attenuates M2 macrophage activation and protects against fungal spore-induced allergic airway disease.
|
J Allergy Clin Immunol
|
2010
|
1.22
|
|
34
|
TLR9 differentiates rapidly from slowly progressing forms of idiopathic pulmonary fibrosis.
|
Sci Transl Med
|
2010
|
1.21
|
|
35
|
Lack of chemokine receptor CCR5 promotes murine fulminant liver failure by preventing the apoptosis of activated CD1d-restricted NKT cells.
|
J Immunol
|
2005
|
1.21
|
|
36
|
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease.
|
PLoS One
|
2013
|
1.20
|
|
37
|
Macrophages in allergic asthma: fine-tuning their pro- and anti-inflammatory actions for disease resolution.
|
J Interferon Cytokine Res
|
2011
|
1.20
|
|
38
|
Human pulmonary fibroblasts exhibit altered interleukin-4 and interleukin-13 receptor subunit expression in idiopathic interstitial pneumonia.
|
Am J Pathol
|
2004
|
1.20
|
|
39
|
Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice.
|
FASEB J
|
2002
|
1.19
|
|
40
|
Role of CCR4 ligands, CCL17 and CCL22, during Schistosoma mansoni egg-induced pulmonary granuloma formation in mice.
|
Am J Pathol
|
2004
|
1.18
|
|
41
|
The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis.
|
Am J Respir Crit Care Med
|
2013
|
1.17
|
|
42
|
Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection.
|
Am J Pathol
|
2011
|
1.16
|
|
43
|
CCL3/MIP-1alpha is pro-inflammatory in murine T cell-mediated hepatitis by recruiting CCR1-expressing CD4(+) T cells to the liver.
|
Eur J Immunol
|
2004
|
1.16
|
|
44
|
CCR1 and CC chemokine ligand 5 interactions exacerbate innate immune responses during sepsis.
|
J Immunol
|
2004
|
1.16
|
|
45
|
CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis.
|
Am J Pathol
|
2007
|
1.15
|
|
46
|
Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts.
|
Am J Pathol
|
2003
|
1.15
|
|
47
|
Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila.
|
Infect Immun
|
2008
|
1.14
|
|
48
|
TLR9 activation is a key event for the maintenance of a mycobacterial antigen-elicited pulmonary granulomatous response.
|
Eur J Immunol
|
2007
|
1.13
|
|
49
|
Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages.
|
BMC Immunol
|
2010
|
1.13
|
|
50
|
Obligatory role for interleukin-13 in obstructive lesion development in airway allografts.
|
Am J Pathol
|
2006
|
1.11
|
|
51
|
The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A.
|
J Clin Invest
|
2011
|
1.10
|
|
52
|
Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.
|
Am J Pathol
|
2007
|
1.10
|
|
53
|
CXCR2 is necessary for the development and persistence of chronic fungal asthma in mice.
|
J Immunol
|
2002
|
1.09
|
|
54
|
Chemokines in the pathogenesis of liver disease: so many players with poorly defined roles.
|
Clin Sci (Lond)
|
2003
|
1.08
|
|
55
|
Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice.
|
Infect Immun
|
2008
|
1.07
|
|
56
|
Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis.
|
Am J Respir Crit Care Med
|
2009
|
1.06
|
|
57
|
Notch signaling mediates TGF-β1-induced epithelial-mesenchymal transition through the induction of Snai1.
|
Int J Biochem Cell Biol
|
2012
|
1.06
|
|
58
|
Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes.
|
PLoS One
|
2013
|
1.05
|
|
59
|
Deleterious role of TLR3 during hyperoxia-induced acute lung injury.
|
Am J Respir Crit Care Med
|
2008
|
1.05
|
|
60
|
Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.
|
Am J Pathol
|
2013
|
1.05
|
|
61
|
A critical role for CCR2/MCP-1 interactions in the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation.
|
Blood
|
2003
|
1.03
|
|
62
|
Inhibition of SCF attenuates peribronchial remodeling in chronic cockroach allergen-induced asthma.
|
Lab Invest
|
2006
|
1.03
|
|
63
|
C-C chemokine ligand 2/monocyte chemoattractant protein-1 directly inhibits NKT cell IL-4 production and is hepatoprotective in T cell-mediated hepatitis in the mouse.
|
J Immunol
|
2003
|
1.03
|
|
64
|
The chemokine CCL6 promotes innate immunity via immune cell activation and recruitment.
|
J Immunol
|
2007
|
1.03
|
|
65
|
Toll-like receptors, Notch ligands, and cytokines drive the chronicity of lung inflammation.
|
Proc Am Thorac Soc
|
2007
|
1.03
|
|
66
|
Stem cell factor induces eosinophil activation and degranulation: mediator release and gene array analysis.
|
Blood
|
2002
|
1.03
|
|
67
|
Role of macrophage chemoattractant protein-1 in acute inflammation after lung contusion.
|
Am J Respir Cell Mol Biol
|
2012
|
1.01
|
|
68
|
Therapeutic targeting of IL-4- and IL-13-responsive cells in pulmonary fibrosis.
|
Immunol Res
|
2004
|
1.01
|
|
69
|
Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus.
|
Am J Physiol Gastrointest Liver Physiol
|
2008
|
1.01
|
|
70
|
Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury.
|
Am J Physiol Lung Cell Mol Physiol
|
2010
|
1.00
|
|
71
|
Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile.
|
Am J Pathol
|
2006
|
0.99
|
|
72
|
Serological investigation of the collagen degradation profile of patients with chronic obstructive pulmonary disease or idiopathic pulmonary fibrosis.
|
Biomark Insights
|
2012
|
0.99
|
|
73
|
STAT4 signal pathways regulate inflammation and airway physiology changes in allergic airway inflammation locally via alteration of chemokines.
|
J Immunol
|
2003
|
0.97
|
|
74
|
The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infection.
|
PLoS Pathog
|
2011
|
0.97
|
|
75
|
Respiratory viral infections drive chemokine expression and exacerbate the asthmatic response.
|
J Allergy Clin Immunol
|
2006
|
0.96
|
|
76
|
Repeated exposure to Aspergillus fumigatus conidia results in CD4+ T cell-dependent and -independent pulmonary arterial remodeling in a mixed Th1/Th2/Th17 microenvironment that requires interleukin-4 (IL-4) and IL-10.
|
Infect Immun
|
2011
|
0.96
|
|
77
|
CCR4 is a key modulator of innate immune responses.
|
J Immunol
|
2006
|
0.95
|
|
78
|
ATLa, an aspirin-triggered lipoxin A4 synthetic analog, prevents the inflammatory and fibrotic effects of bleomycin-induced pulmonary fibrosis.
|
J Immunol
|
2009
|
0.95
|
|
79
|
Dendritic cells at the interface of innate and acquired immunity: the role for epigenetic changes.
|
J Leukoc Biol
|
2007
|
0.95
|
|
80
|
Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation.
|
BMC Pulm Med
|
2012
|
0.94
|
|
81
|
Targeting interleukin-13 with tralokinumab attenuates lung fibrosis and epithelial damage in a humanized SCID idiopathic pulmonary fibrosis model.
|
Am J Respir Cell Mol Biol
|
2014
|
0.94
|
|
82
|
STAT3-mediated signaling dysregulates lung fibroblast-myofibroblast activation and differentiation in UIP/IPF.
|
Am J Pathol
|
2012
|
0.94
|
|
83
|
The role of CC chemokine receptor 5 (CCR5) and RANTES/CCL5 during chronic fungal asthma in mice.
|
FASEB J
|
2001
|
0.94
|
|
84
|
T regulatory cells and attenuated bleomycin-induced fibrosis in lungs of CCR7-/- mice.
|
Fibrogenesis Tissue Repair
|
2010
|
0.93
|
|
85
|
CD154-CD40 interactions drive hepatocyte apoptosis in murine fulminant hepatitis.
|
Hepatology
|
2005
|
0.93
|
|
86
|
CCR7 deficiency on dendritic cells enhances fungal clearance in a murine model of pulmonary invasive aspergillosis.
|
J Immunol
|
2009
|
0.92
|
|
87
|
The role of CCL3/macrophage inflammatory protein-1alpha in experimental colitis.
|
Eur J Pharmacol
|
2004
|
0.92
|
|
88
|
CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling.
|
Eur J Immunol
|
2008
|
0.92
|
|
89
|
Marked improvement of severe lung immunopathology by influenza-associated pneumococcal superinfection requires the control of both bacterial replication and host immune responses.
|
Am J Pathol
|
2013
|
0.92
|
|
90
|
Stem cell factor attenuates liver damage in a murine model of acetaminophen-induced hepatic injury.
|
Lab Invest
|
2003
|
0.91
|
|
91
|
Alterations in cytokine/chemokine expression during organ-to-organ communication established via acetaminophen-induced toxicity.
|
Exp Mol Pathol
|
2003
|
0.91
|
|
92
|
Triggering receptor expressed on myeloid cells-1 (TREM-1) modulates immune responses to Aspergillus fumigatus during fungal asthma in mice.
|
Immunol Invest
|
2011
|
0.90
|
|
93
|
Contrasting roles for CXCR2 during experimental colitis.
|
Exp Mol Pathol
|
2004
|
0.90
|
|
94
|
Airway delivery of soluble mycobacterial antigens restores protective mucosal immunity by single intramuscular plasmid DNA tuberculosis vaccination: role of proinflammatory signals in the lung.
|
J Immunol
|
2008
|
0.89
|
|
95
|
Absence of CC chemokine receptor 8 enhances innate immunity during septic peritonitis.
|
FASEB J
|
2005
|
0.89
|
|
96
|
Reactive nitrogen species augment fibroblast-mediated collagen gel contraction, mediator production, and chemotaxis.
|
Am J Respir Cell Mol Biol
|
2006
|
0.88
|
|
97
|
Inefficient lymph node sensitization during respiratory viral infection promotes IL-17-mediated lung pathology.
|
J Immunol
|
2010
|
0.88
|
|
98
|
Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.
|
Blood
|
2013
|
0.87
|
|
99
|
Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis.
|
Immunology
|
2010
|
0.87
|
|
100
|
Chemokine receptors in asthma: searching for the correct immune targets.
|
J Immunol
|
2003
|
0.87
|
|
101
|
MHV68 latency modulates the host immune response to influenza A virus.
|
Inflammation
|
2013
|
0.87
|
|
102
|
Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
|
J Immunol
|
2014
|
0.87
|
|
103
|
Targeting ST2L potentiates CpG-mediated therapeutic effects in a chronic fungal asthma model.
|
Am J Pathol
|
2011
|
0.87
|
|
104
|
Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation.
|
Am J Respir Crit Care Med
|
2009
|
0.86
|
|
105
|
TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung.
|
Eur J Immunol
|
2008
|
0.86
|
|
106
|
Toll like receptor 3 plays a critical role in the progression and severity of acetaminophen-induced hepatotoxicity.
|
PLoS One
|
2013
|
0.86
|
|
107
|
Remission of chronic fungal asthma in the absence of CCR8.
|
J Allergy Clin Immunol
|
2007
|
0.86
|
|
108
|
Interleukin-13 fusion cytotoxin arrests Schistosoma mansoni egg-induced pulmonary granuloma formation in mice.
|
Am J Pathol
|
2002
|
0.86
|
|
109
|
Intranasal CpG therapy attenuated experimental fungal asthma in a TLR9-dependent and -independent manner.
|
Int Arch Allergy Immunol
|
2009
|
0.85
|
|
110
|
Chemokines and cytokines: axis and allies in asthma and allergy.
|
Cytokine Growth Factor Rev
|
2003
|
0.84
|
|
111
|
IL-13 immunotoxin accelerates resolution of lung pathological changes triggered by silica particles in mice.
|
J Immunol
|
2013
|
0.84
|
|
112
|
Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice.
|
Br J Pharmacol
|
2005
|
0.83
|
|
113
|
Delta-like 4 differentially regulates murine CD4 T cell expansion via BMI1.
|
PLoS One
|
2010
|
0.83
|
|
114
|
Chemokines and their receptors in chronic pulmonary disease.
|
Curr Drug Targets Inflamm Allergy
|
2005
|
0.83
|
|
115
|
The chemokine receptor CCR6 is an important component of the innate immune response.
|
Eur J Immunol
|
2007
|
0.83
|
|
116
|
Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.
|
J Immunol
|
2010
|
0.82
|
|
117
|
Eotaxin/CCL11 is involved in acute, but not chronic, allergic airway responses to Aspergillus fumigatus.
|
Am J Physiol Lung Cell Mol Physiol
|
2002
|
0.81
|
|
118
|
Plasmin overcomes resistance to prostaglandin E2 in fibrotic lung fibroblasts by reorganizing protein kinase A signaling.
|
J Biol Chem
|
2011
|
0.81
|
|
119
|
Intrapulmonary targeting of RANTES/CCL5-responsive cells prevents chronic fungal asthma.
|
Eur J Immunol
|
2003
|
0.81
|
|
120
|
Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis.
|
Infect Immun
|
2005
|
0.81
|
|
121
|
IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness.
|
Am J Physiol Gastrointest Liver Physiol
|
2007
|
0.81
|
|
122
|
Chemokines in allergic aspergillosis--from animal models to human lung diseases.
|
Inflamm Allergy Drug Targets
|
2006
|
0.80
|
|
123
|
Inhibition of lung metastasis by chemokine CCL17-mediated in vivo silencing of genes in CCR4+ Tregs.
|
J Immunother
|
2013
|
0.80
|
|
124
|
Role of Th1/Th17 balance regulated by T-bet in a mouse model of Mycobacterium avium complex disease.
|
J Immunol
|
2014
|
0.80
|
|
125
|
Therapeutic efficacy of Cintredekin Besudotox (IL13-PE38QQR) in murine lung fibrosis is unaffected by immunity to Pseudomonas aeruginosa exotoxin A.
|
PLoS One
|
2010
|
0.79
|
|
126
|
Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung.
|
PLoS One
|
2013
|
0.78
|
|
127
|
Acute Myocardial Infarction and Pulmonary Diseases Result in Two Different Degradation Profiles of Elastin as Quantified by Two Novel ELISAs.
|
PLoS One
|
2013
|
0.78
|
|
128
|
Danger-associated molecular patterns and danger signals in idiopathic pulmonary fibrosis.
|
Am J Respir Cell Mol Biol
|
2014
|
0.78
|
|
129
|
Update in diffuse parenchymal lung disease 2006.
|
Am J Respir Crit Care Med
|
2007
|
0.78
|
|
130
|
Therapeutic DNA vaccine reduces schistosoma mansoni-induced tissue damage through cytokine balance and decreased migration of myofibroblasts.
|
Am J Pathol
|
2011
|
0.77
|
|
131
|
CCR5 antagonists: the answer to inflammatory disease?
|
Expert Opin Ther Pat
|
2006
|
0.77
|
|
132
|
Generation of bleomycin-induced lung fibrosis is independent of IL-16.
|
Cytokine
|
2009
|
0.76
|
|
133
|
Intrapulmonary, adenovirus-mediated overexpression of KARAP/DAP12 enhances fungal clearance during invasive aspergillosis.
|
Infect Immun
|
2005
|
0.76
|
|
134
|
Update in diffuse parenchymal lung disease 2007.
|
Am J Respir Crit Care Med
|
2008
|
0.76
|
|
135
|
Mice genetically lacking endothelial selectins are resistant to the lethality in septic peritonitis.
|
Exp Mol Pathol
|
2002
|
0.76
|
|
136
|
Surrogate antibodies that specifically bind and neutralize CCL17 but not CCL22.
|
Monoclon Antib Immunodiagn Immunother
|
2013
|
0.76
|
|
137
|
Double-Stranded RNA Interacts With Toll-Like Receptor 3 in Driving the Acute Inflammatory Response Following Lung Contusion.
|
Crit Care Med
|
2016
|
0.75
|
|
138
|
Role of growth arrest-specific gene 6 in the development of fungal allergic airway disease in mice.
|
Am J Respir Cell Mol Biol
|
2014
|
0.75
|
|
139
|
Herpesvirus-associated pulmonary hypertension?
|
Am J Respir Crit Care Med
|
2005
|
0.75
|
|
140
|
Gas6'ing the innate immune response during experimental asthma.
|
Ann Am Thorac Soc
|
2014
|
0.75
|