Epigenetic mechanisms in bone.

A look behind the scenes: the risk and pathogenesis of primary osteoporosis. Nat Rev Rheumatol (2015) 0.90

Epigenetic pathways regulating bone homeostasis: potential targeting for intervention of skeletal disorders. Curr Osteoporos Rep (2014) 0.82

New horizons in treatment of osteoporosis. Daru (2017) 0.79

Involvement of MicroRNA-210 Demethylation in Steroid-associated Osteonecrosis of the Femoral Head. Sci Rep (2016) 0.78

Epigenetic Mechanisms in Bone Biology and Osteoporosis: Can They Drive Therapeutic Choices? Int J Mol Sci (2016) 0.78

Epigenetics of osteoarticular diseases: recent developments. Rheumatol Int (2015) 0.78

How to interpret epigenetic association studies: a guide for clinicians. Bonekey Rep (2016) 0.75

Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation. Int J Biol Sci (2016) 0.75

Lysine-specific demethylase 1 inhibitor rescues the osteogenic ability of mesenchymal stem cells under osteoporotic conditions by modulating H3K4 methylation. Bone Res (2016) 0.75

MiR-148a the epigenetic regulator of bone homeostasis is increased in plasma of osteoporotic postmenopausal women. Wien Klin Wochenschr (2016) 0.75

Histone deacetylases and their roles in mineralized tissue regeneration. Bone Rep (2017) 0.75

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48

Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res (2012) 1.58

Increased lipoprotein lipase activity in non-small cell lung cancer tissue predicts shorter patient survival. Arch Med Res (2009) 1.47

Molecular mechanisms of insulin resistance and associated diseases. Clin Chim Acta (2006) 1.37

Expression of bone resorption genes in osteoarthritis and in osteoporosis. J Bone Miner Metab (2007) 1.12

Association of the osteoprotegerin gene polymorphisms with bone mineral density in postmenopausal women. Maturitas (2005) 1.03

Osteoimmunology and the influence of pro-inflammatory cytokines on osteoclasts. Biochem Med (Zagreb) (2013) 0.97

Exonic, but not intronic polymorphisms of ESR1 gene might influence the hypolipemic effect of raloxifene. J Steroid Biochem Mol Biol (2007) 0.94

The relationship between osteoclastogenic and anti-osteoclastogenic pro-inflammatory cytokines differs in human osteoporotic and osteoarthritic bone tissues. J Biomed Sci (2012) 0.93

A microarray based identification of osteoporosis-related genes in primary culture of human osteoblasts. Bone (2009) 0.93

New insights into adipose tissue dysfunction in insulin resistance. Clin Chem Lab Med (2011) 0.92

Gene-gene interactions in RANK/RANKL/OPG system influence bone mineral density in postmenopausal women. J Steroid Biochem Mol Biol (2009) 0.87

Arsenic trioxide (ATO) influences the gene expression of metallothioneins in human glioblastoma cells. Biol Trace Elem Res (2012) 0.85

Antioxidant enzymes GSR, SOD1, SOD2, and CAT gene variants and bone mineral density values in postmenopausal women: a genetic association analysis. Menopause (2012) 0.85

No major effect of estrogen receptor beta gene RsaI polymorphism on bone mineral density and response to alendronate therapy in postmenopausal osteoporosis. J Steroid Biochem Mol Biol (2002) 0.84

Triglyceride metabolism in bone tissue is associated with osteoblast and osteoclast differentiation: a gene expression study. J Bone Miner Metab (2013) 0.84

Treatment with low-dose atorvastatin, losartan, and their combination increases expression of vasoactive-related genes in rat aortas. J Cardiovasc Pharmacol Ther (2012) 0.84

Lipoprotein lipase activity and gene expression in lung cancer and in adjacent noncancer lung tissue. Exp Lung Res (2007) 0.84

Vitamin D receptor gene polymorphism and bone metabolism during low-dose oral contraceptive use in young women. Contraception (2003) 0.83

The combinations of polymorphisms in vitamin D receptor, osteoprotegerin and tumour necrosis factor superfamily member 11 genes are associated with bone mineral density. J Mol Endocrinol (2009) 0.83

TNFRSF11B gene polymorphisms 1181G > C and 245T > G as well as haplotype CT influence bone mineral density in postmenopausal women. Maturitas (2011) 0.83

Effects of UGT1A1*28 polymorphism on raloxifene pharmacokinetics and pharmacodynamics. Br J Clin Pharmacol (2009) 0.83

Increased apolipoprotein E gene expression and protein concentration in lung cancer tissue do not contribute to the clinical assessment of non-small cell lung cancer patients. Arch Med Res (2008) 0.83

Activity or mass concentration of bone-specific alkaline phosphatase as a marker of bone formation. Clin Chem Lab Med (2007) 0.83

Development of a new DHPLC assay for genotyping UGT1A (TA)n polymorphism associated with Gilbert's syndrome. Biochem Med (Zagreb) (2011) 0.82

Analysis of association of LRP5, LRP6, SOST, DKK1, and CTNNB1 genes with bone mineral density in a Slovenian population. Calcif Tissue Int (2009) 0.81

Analysis of CYP2C9*2, CYP2C19*2, and CYP2D6*4 polymorphisms in patients with type 2 diabetes mellitus. Bosn J Basic Med Sci (2010) 0.81

Association between 11beta-hydroxysteroid dehydrogenase type 1 gene polymorphisms and metabolic syndrome in Bosnian population. Biochem Med (Zagreb) (2012) 0.81

Atorvastatin in stable angina patients lowers CCL2 and ICAM1 expression: pleiotropic evidence from plasma mRNA analyses. Clin Biochem (2013) 0.81

Decreased lipin 1 beta expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome. Eur J Endocrinol (2008) 0.81

Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes. Med Glas (Zenica) (2011) 0.81

Increased levels of osteoprotegerin in hemodialysis patients. Clin Chem Lab Med (2002) 0.80

Osteoblastogenesis and adipogenesis are higher in osteoarthritic than in osteoporotic bone tissue. Arch Med Res (2011) 0.80

Optimization of high-resolution melting analysis for simultaneous genotyping of two 11β-hydroxysteroid dehydrogenase type 1 gene polymorphisms. Genet Test Mol Biomarkers (2010) 0.79

Development and validation of a liquid chromatography-tandem mass spectrometry assay for determination of raloxifene and its metabolites in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2007) 0.79

The antioxidant enzyme GPX1 gene polymorphisms are associated with low BMD and increased bone turnover markers. Dis Markers (2010) 0.79

Inverse correlation of carotid intima-media thickness with raloxifene serum levels in osteoporosis. Wien Klin Wochenschr (2014) 0.78

PPARG gene promoter polymorphism is associated with non-traumatic hip fracture risk in the elderly Slovenian population: a pilot study. Clin Biochem (2011) 0.78

Increased bone resorption in HD patients: is it caused by elevated RANKL synthesis? Nephrol Dial Transplant (2005) 0.78

Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene. J Transl Med (2012) 0.78

Lipoprotein lipase in non-small cell lung cancer tissue is highly expressed in a subpopulation of tumor-associated macrophages. Pathol Res Pract (2013) 0.78

Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome. Eur J Endocrinol (2008) 0.78

Osteoarthritic versus osteoporotic bone and intra-skeletal variations in normal bone: evaluation with µCT and bone histomorphometry. J Orthop Res (2013) 0.78

Optimisation of methods for quantifying plasma mRNA levels from genes responsible for coronary artery plaque development and destabilization. Med Glas (Zenica) (2011) 0.77

Association of TNFSF11 gene promoter polymorphisms with bone mineral density in postmenopausal women. Maturitas (2006) 0.77

-1227C>T polymorphism in the pleiotrophin gene promoter influences bone mineral density in postmenopausal women. Mol Genet Metab (2011) 0.77

Raloxifene pharmacodynamics is influenced by genetic variants in the RANKL/RANK/OPG system and in the Wnt signaling pathway. Drug Metabol Drug Interact (2014) 0.77

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe. Clin Chem Lab Med (2015) 0.77

Opposite effects of GSTM1--and GSTT1: gene deletion variants on bone mineral density. Dis Markers (2011) 0.77

Tumour necrosis factor superfamily member 11 gene promoter polymorphisms modulate promoter activity and influence bone mineral density in postmenopausal women with osteoporosis. J Mol Endocrinol (2008) 0.77

CTSS activation coexists with CD40 activation in human atheroma: evidence from plasma mRNA analysis. Clin Biochem (2011) 0.76

Atorvastatin treatment increases plasma bilirubin but not HMOX1 expression in stable angina patients. Scand J Clin Lab Invest (2015) 0.76

Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment. Transl Res (2012) 0.76

Testing GSTP1 genotypes and haplotypes interactions in Slovenian post-/pre-menopausal women: novel involvement of glutathione S-transferases in bone remodeling process. Maturitas (2012) 0.76

Cathepsin K predicts femoral neck bone mineral density change in nonosteoporotic peri- and early postmenopausal women. Menopause (2008) 0.76

Hypoxia mimetic deferoxamine influences the expression of histone acetylation- and DNA methylation-associated genes in osteoblasts. Connect Tissue Res (2015) 0.76

Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity. J Steroid Biochem Mol Biol (2010) 0.76

XbaI polymorphism of the estrogen receptor alpha gene influences the effect of raloxifene on the endothelial function. Maturitas (2010) 0.76

Association of NAT2 polymorphisms with type 2 diabetes in a population from Bosnia and Herzegovina. Arch Med Res (2011) 0.75

Interleukin-1α gene variants influence bone mineral density and the risk of osteoporotic hip fractures in elderly Slovenian people. Clin Chem Lab Med (2012) 0.75

Highlights from the latest pharmacogenomic genome-wide association studies. Pharmacogenomics (2013) 0.75

Monitoring of imatinib targeted delivery in human leukocytes. Eur J Pharm Sci (2013) 0.75

Genotyping UGT1A1(TA)(n) polymorphism rare variants by high resolution melting curve analysis. Clin Chim Acta (2010) 0.75

The impact of gene polymorphisms in angiotensin receptor 1 and aldosterone synthase in peritoneal dialysis patients. Clin Nephrol (2017) 0.75

Increased DAPK1 but decreased CCL2 plasma levels of nucleic acids in patients with stable angina. Biochem Med (Zagreb) (2011) 0.75

BMD values and GSTM3 gene polymorphisms in combination with GSTT1/GSTM1 genes: a genetic association study in Slovenian elderly. Gerontology (2012) 0.75

Increased plasma levels of CATS mRNA but not CATB mRNA in patients with coronary atherosclerosis. Clin Biochem (2010) 0.75

Effect of cetirizine, a histamine (H(1)) receptor antagonist, on bone modeling during orthodontic tooth movement in rats. Am J Orthod Dentofacial Orthop (2011) 0.75

Bone microRNAs and aging. Curr Pharm Biotechnol (2017) 0.75

The "Rise-Peak-Fall" Pattern of Time Dependency of the Cardiovascular Pleiotropic Effects of Treatment With Low-dose Atorvastatin, Losartan, and a Combination Thereof in Rats. J Cardiovasc Pharmacol (2016) 0.75

Report from the European Society of Pharmacogenomics and Theranostics (ESPT) Inaugural Symposium 2011 in Bled. Drug Metabol Drug Interact (2012) 0.75

Osteoporosis pharmacogenomics: recent insights and future perspectives. Pharmacogenomics (2013) 0.75

Frequencies of Q188R and N314D mutations and IVS5-24g>A intron variation in the galactose-1-phosphate uridyl transferase (GALT) gene in the Slovenian population. Clin Chem Lab Med (2002) 0.75

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe. Drug Metabol Personal Ther (2015) 0.75

Interrelated cathepsin S-lowering and LDL subclass profile improvements induced by atorvastatin in the plasma of stable angina patients. J Atheroscler Thromb (2014) 0.75

Analysis of CYP3A4*1B and CYP3A5*3 polymorphisms in population of Bosnia and Herzegovina. Med Glas (Zenica) (2011) 0.75