Published in Angew Chem Int Ed Engl on December 16, 2013
Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites. EMBO J (2015) 0.94
BLM helicase facilitates telomere replication during leading strand synthesis of telomeres. J Cell Biol (2015) 0.88
Thermodynamic fingerprints of ligand binding to human telomeric G-quadruplexes. Nucleic Acids Res (2015) 0.78
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G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structures in vitro and are unwound by the Pfh1 DNA helicase. Nucleic Acids Res (2016) 0.77
Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes. Nucleic Acids Res (2015) 0.76
Chelerythrine down regulates expression of VEGFA, BCL2 and KRAS by arresting G-Quadruplex structures at their promoter regions. Sci Rep (2017) 0.76
Loop flexibility in human telomeric quadruplex small-molecule complexes. Nucleic Acids Res (2015) 0.75
A Nitroxide-Tagged Platinum(II) Complex Enables the Identification of a DNA G-Quadruplex Binding Mode. Chemistry (2016) 0.75
Distance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexes. Phys Chem Chem Phys (2016) 0.75
A Nucleus-Imaging Probe That Selectively Stabilizes a Minor Conformation of c-MYC G-quadruplex and Down-regulates c-MYC Transcription in Human Cancer Cells. Sci Rep (2015) 0.75
Evidences for Piperine inhibiting cancer by targeting human G-quadruplex DNA sequences. Sci Rep (2016) 0.75
A Dual-Specific Targeting Approach Based on the Simultaneous Recognition of Duplex and Quadruplex Motifs. Sci Rep (2017) 0.75
Human Telomeric G-Quadruplex Structures and G-Quadruplex-Interactive Compounds. Methods Mol Biol (2017) 0.75
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs. Chem Biol (2004) 5.44
Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature (2006) 3.90
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics. Nucleic Acids Res (2007) 3.49
Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold. J Am Chem Soc (2006) 3.26
Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen. Mol Cell (2006) 2.63
Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat Struct Mol Biol (2005) 2.50
A hitchhiker's guide to G-quadruplex ligands. Org Biomol Chem (2007) 2.27
Natural and pharmacological regulation of telomerase. Nucleic Acids Res (2002) 1.92
G-quadruplex-induced instability during leading-strand replication. EMBO J (2011) 1.77
Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers. J Am Chem Soc (2009) 1.74
(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex. J Am Chem Soc (2005) 1.51
Structure of human telomeric DNA in crowded solution. J Am Chem Soc (2011) 1.44
Fluorescence-based melting assays for studying quadruplex ligands. Methods (2007) 1.38
G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms. Carcinogenesis (2010) 1.34
Highly efficient G-quadruplex recognition by bisquinolinium compounds. J Am Chem Soc (2007) 1.34
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action. Proc Natl Acad Sci U S A (2007) 1.29
Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae. Nucleic Acids Res (2010) 1.26
Bulges in G-quadruplexes: broadening the definition of G-quadruplex-forming sequences. J Am Chem Soc (2013) 1.26
Coexistence of two distinct G-quadruplex conformations in the hTERT promoter. J Am Chem Soc (2010) 1.18
Stabilization and structure of telomeric and c-myc region intramolecular G-quadruplexes: the role of central cations and small planar ligands. J Am Chem Soc (2007) 1.16
Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution. J Am Chem Soc (2009) 1.16
Rudimentary G-quadruplex-based telomere capping in Saccharomyces cerevisiae. Nat Struct Mol Biol (2011) 1.14
A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells. Nucleic Acids Res (2010) 1.13
NMR spectroscopy of G-quadruplexes. Methods (2012) 1.12
Exclusive platination of loop adenines in the human telomeric G-quadruplex. Org Biomol Chem (2009) 1.07
Solution structures of all parallel-stranded monomeric and dimeric G-quadruplex scaffolds of the human c-kit2 promoter. Nucleic Acids Res (2010) 1.04
Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad. Nucleic Acids Res (2009) 1.02
Structure of long human telomeric RNA (TERRA): G-quadruplexes formed by four and eight UUAGGG repeats are stable building blocks. Biochemistry (2011) 0.99
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem (2013) 0.99
Formation of pearl-necklace monomorphic G-quadruplexes in the human CEB25 minisatellite. J Am Chem Soc (2012) 0.98
Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity. Nucleic Acids Res (2011) 0.98
DNA mismatch-specific base flipping by a bisacridine macrocycle. Chembiochem (2003) 0.98
The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes. Org Biomol Chem (2007) 0.97
G-quartets assembly within a G-rich DNA flap. A possible event at the center of the HIV-1 genome. Nucleic Acids Res (2002) 0.97
Visualizing the quadruplex: from fluorescent ligands to light-up probes. Top Curr Chem (2013) 0.97
A platinum-quinacridine hybrid as a G-quadruplex ligand. J Biol Inorg Chem (2007) 0.95
Structure of the human telomere in Na+ solution: an antiparallel (2+2) G-quadruplex scaffold reveals additional diversity. Nucleic Acids Res (2013) 0.94
G-quadruplex recognition by quinacridines: a SAR, NMR, and biological study. ChemMedChem (2007) 0.94
Engineering bisquinolinium/thiazole orange conjugates for fluorescent sensing of G-quadruplex DNA. Angew Chem Int Ed Engl (2009) 0.93
Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands. Bioorg Med Chem Lett (2006) 0.93
Guanine base stacking in G-quadruplex nucleic acids. Nucleic Acids Res (2012) 0.92
Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures. Anal Bioanal Chem (2011) 0.91
Giardia telomeric sequence d(TAGGG)4 forms two intramolecular G-quadruplexes in K+ solution: effect of loop length and sequence on the folding topology. J Am Chem Soc (2009) 0.91
Plasmodium telomeric sequences: structure, stability and quadruplex targeting by small compounds. Chembiochem (2008) 0.90
DNA switches on the two-photon efficiency of an ultrabright triphenylamine fluorescent probe specific of AT regions. J Am Chem Soc (2013) 0.90
Efficient suppression of gene expression by targeting 5'-UTR-based RNA quadruplexes with bisquinolinium compounds. Chembiochem (2011) 0.90
A metal-mediated conformational switch controls G-quadruplex binding affinity. Angew Chem Int Ed Engl (2008) 0.90
A novel G-quadruplex motif modulates promoter activity of human thymidine kinase 1. FEBS J (2010) 0.90
Formation of G-quadruplexes in poly-G sequences: structure of a propeller-type parallel-stranded G-quadruplex formed by a G₁₅ stretch. Biochemistry (2014) 0.89
Structural basis of DNA quadruplex-duplex junction formation. Angew Chem Int Ed Engl (2013) 0.89
HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges. Nucleic Acids Res (2011) 0.89
Solution structure of an intramolecular (3 + 1) human telomeric G-quadruplex bound to a telomestatin derivative. J Am Chem Soc (2013) 0.89
Selective recognition of pyrimidine-pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalators. Nucleic Acids Res (2008) 0.88
Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures. Biochimie (2011) 0.88
Monomer-dimer equilibrium for the 5'-5' stacking of propeller-type parallel-stranded G-quadruplexes: NMR structural study. Chemistry (2012) 0.87
Human telomeres that contain (CTAGGG)n repeats show replication dependent instability in somatic cells and the male germline. Nucleic Acids Res (2009) 0.87
An acyclic oligoheteroaryle that discriminates strongly between diverse G-quadruplex topologies. Angew Chem Int Ed Engl (2011) 0.86
Inhibition of dicing of guanosine-rich shRNAs by quadruplex-binding compounds. Chembiochem (2008) 0.86
Formation of a stacked dimeric G-quadruplex containing bulges by the 5'-terminal region of human telomerase RNA (hTERC). Biochemistry (2014) 0.85
Sequence-specific Methyltransferase-Induced Labelling (SMILing) of plasmid DNA for studying cell transfection. Bioorg Med Chem (2007) 0.85
Macrocyclic DNA-mismatch-binding ligands: structural determinants of selectivity. Chemistry (2010) 0.84
Vinyl-pyridinium triphenylamines: novel far-red emitters with high photostability and two-photon absorption properties for staining DNA. Chembiochem (2007) 0.84
Structure and conformational dynamics of a stacked dimeric G-quadruplex formed by the human CEB1 minisatellite. J Am Chem Soc (2014) 0.84
Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies. Chemistry (2010) 0.84
Stimulation of ribosomal frameshifting by RNA G-quadruplex structures. Nucleic Acids Res (2013) 0.83
"One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition. J Nucleic Acids (2010) 0.83
Nucleic acids targeted to drugs: SELEX against a quadruplex ligand. Biochimie (2011) 0.83
A novel chair-type G-quadruplex formed by a Bombyx mori telomeric sequence. Nucleic Acids Res (2008) 0.83
Synthetic strategies to derivatizable triphenylamines displaying high two-photon absorption. J Org Chem (2008) 0.83
Ligand-induced conformational changes with cation ejection upon binding to human telomeric DNA G-quadruplexes. J Am Chem Soc (2015) 0.83
Formation of (3+1) G-quadruplexes with a long loop by human telomeric DNA spanning five or more repeats. J Am Chem Soc (2011) 0.83
Stabilization of the G-quadruplex at the VEGF IRES represses cap-independent translation. RNA Biol (2015) 0.82
Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines. BMC Res Notes (2012) 0.82
Neomycin-capped aromatic platforms: quadruplex DNA recognition and telomerase inhibition. Org Biomol Chem (2006) 0.82
Effects of site-specific guanine C8-modifications on an intramolecular DNA G-quadruplex. Biophys J (2011) 0.82
A fluorescent bisanthracene macrocycle discriminates between matched and mismatch-containing DNA. Chemistry (2009) 0.81
DNA structures from phosphate chemical shifts. Nucleic Acids Res (2009) 0.81
FRET templated by G-quadruplex DNA: a specific ternary interaction using an original pair of donor/acceptor partners. J Am Chem Soc (2006) 0.81
Telomere targeting with a new G4 ligand enhances radiation-induced killing of human glioblastoma cells. Mol Cancer Ther (2011) 0.81
Finding needles in a basestack: recognition of mismatched base pairs in DNA by small molecules. Chem Soc Rev (2014) 0.81
Photo-cross-linking probes for trapping G-quadruplex DNA. Angew Chem Int Ed Engl (2013) 0.81
Recognition of G-quadruplex DNA by triangular star-shaped compounds: with or without side chains? Chemistry (2011) 0.81
Structure of human telomeric RNA (TERRA): stacking of two G-quadruplex blocks in K(+) solution. Biochemistry (2013) 0.80
Identification of trinucleotide repeat ligands with a FRET melting assay. Chembiochem (2008) 0.80