PubRank

Nicholas W Lukacs

Author PubWeight™ 162.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012 20.08
2 Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 2009 3.76
3 TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events. J Exp Med 2008 3.62
4 Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med 2006 2.77
5 Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection. J Allergy Clin Immunol 2012 2.33
6 Leptin-deficient mice exhibit impaired host defense in Gram-negative pneumonia. J Immunol 2002 2.27
7 Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression. J Virol 2005 2.21
8 Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus. J Exp Med 2006 2.14
9 The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth. Blood 2010 1.97
10 House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection. Proc Natl Acad Sci U S A 2013 1.88
11 Respiratory syncytial virus-induced chemokine production: linking viral replication to chemokine production in vitro and in vivo. J Infect Dis 2004 1.87
12 Regulation of found in inflammatory zone 1 expression in bleomycin-induced lung fibrosis: role of IL-4/IL-13 and mediation via STAT-6. J Immunol 2004 1.83
13 Deletion of TLR3 alters the pulmonary immune environment and mucus production during respiratory syncytial virus infection. J Immunol 2006 1.83
14 A selective novel low-molecular-weight inhibitor of IkappaB kinase-beta (IKK-beta) prevents pulmonary inflammation and shows broad anti-inflammatory activity. Br J Pharmacol 2005 1.73
15 Human rhinovirus 1B exposure induces phosphatidylinositol 3-kinase-dependent airway inflammation in mice. Am J Respir Crit Care Med 2008 1.67
16 A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction. J Virol 2009 1.63
17 Cocaine esterase: interactions with cocaine and immune responses in mice. J Pharmacol Exp Ther 2006 1.55
18 IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease. Am J Pathol 2011 1.55
19 Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation. J Immunol 2009 1.51
20 TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells. J Immunol 2007 1.49
21 Reversal of long-term sepsis-induced immunosuppression by dendritic cells. Blood 2004 1.44
22 TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4. J Clin Invest 2008 1.43
23 H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM-1 and TLR3 expression. FASEB J 2006 1.40
24 Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. J Immunol 2010 1.37
25 Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines. J Exp Med 2007 1.35
26 Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma. Am J Pathol 2002 1.34
27 Predictors of job satisfaction among academic faculty members: do instructional and clinical staff differ? Med Educ 2010 1.33
28 CXCR2 is required for neutrophilic airway inflammation and hyperresponsiveness in a mouse model of human rhinovirus infection. J Immunol 2009 1.28
29 Critical role of IL-1 receptor-associated kinase-M in regulating chemokine-dependent deleterious inflammation in murine influenza pneumonia. J Immunol 2009 1.27
30 TLR3 increases disease morbidity and mortality from vaccinia infection. J Immunol 2008 1.26
31 MyD88-mediated instructive signals in dendritic cells regulate pulmonary immune responses during respiratory virus infection. J Immunol 2007 1.26
32 Septic mice are susceptible to pulmonary aspergillosis. Am J Pathol 2003 1.25
33 A closer look at chemokines and their role in asthmatic responses. Eur J Pharmacol 2006 1.23
34 CXCL10/CXCR3-mediated responses promote immunity to respiratory syncytial virus infection by augmenting dendritic cell and CD8(+) T cell efficacy. Eur J Immunol 2008 1.22
35 RANTES (CCL5) production during primary respiratory syncytial virus infection exacerbates airway disease. Eur J Immunol 2002 1.21
36 CXCR2 regulates respiratory syncytial virus-induced airway hyperreactivity and mucus overproduction. J Immunol 2003 1.20
37 Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism. FASEB J 2007 1.20
38 Airway hyperresponsiveness, but not airway remodeling, is attenuated during chronic pulmonary allergic responses to Aspergillus in CCR4-/- mice. FASEB J 2002 1.19
39 IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome. J Immunol 2007 1.18
40 The balance between plasmacytoid DC versus conventional DC determines pulmonary immunity to virus infections. PLoS One 2008 1.18
41 The gamma interferon receptor is required for the protective pulmonary inflammatory response to Cryptococcus neoformans. Infect Immun 2005 1.15
42 Pulmonary IL-17E (IL-25) production and IL-17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease. J Immunol 2009 1.15
43 Temporal production of CCL28 corresponds to eosinophil accumulation and airway hyperreactivity in allergic airway inflammation. Am J Pathol 2005 1.14
44 CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC. Eur J Immunol 2010 1.13
45 Respiratory syncytial virus-induced CCL5/RANTES contributes to exacerbation of allergic airway inflammation. Eur J Immunol 2003 1.11
46 Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology. Nat Med 2012 1.11
47 Attenuation of allergen-induced responses in CCR6-/- mice is dependent upon altered pulmonary T lymphocyte activation. J Immunol 2005 1.09
48 Chemokines in the pathogenesis of liver disease: so many players with poorly defined roles. Clin Sci (Lond) 2003 1.08
49 IL-13 regulates Th17 secretion of IL-17A in an IL-10-dependent manner. J Immunol 2011 1.07
50 IP-10 mediates selective mononuclear cell accumulation and activation in response to intrapulmonary transgenic expression and during adenovirus-induced pulmonary inflammation. J Interferon Cytokine Res 2005 1.04
51 Inhibition of SCF attenuates peribronchial remodeling in chronic cockroach allergen-induced asthma. Lab Invest 2006 1.03
52 Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses. J Immunol 2011 1.03
53 Toll-like receptors, Notch ligands, and cytokines drive the chronicity of lung inflammation. Proc Am Thorac Soc 2007 1.03
54 Stem cell factor induces eosinophil activation and degranulation: mediator release and gene array analysis. Blood 2002 1.03
55 CCR8 is expressed by antigen-elicited, IL-10-producing CD4+CD25+ T cells, which regulate Th2-mediated granuloma formation in mice. J Immunol 2005 1.02
56 Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling. Am J Pathol 2009 1.02
57 A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease. PLoS One 2011 1.02
58 Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis. J Neuroimmunol 2009 1.02
59 B cell antigen presentation promotes Th2 responses and immunopathology during chronic allergic lung disease. PLoS One 2008 1.01
60 CCR4 participation in Th type 1 (mycobacterial) and Th type 2 (schistosomal) anamnestic pulmonary granulomatous responses. J Immunol 2006 1.00
61 Type I interferon regulates respiratory virus infected dendritic cell maturation and cytokine production. Viral Immunol 2007 1.00
62 Neonatal rhinovirus infection induces mucous metaplasia and airways hyperresponsiveness. J Immunol 2012 1.00
63 Delta-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis. J Immunol 2011 0.99
64 Treatment of cockroach allergen asthma model with imatinib attenuates airway responses. Am J Respir Crit Care Med 2004 0.98
65 Vaccine-elicited CD8+ T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice. J Virol 2012 0.98
66 Amelioration of the cardiovascular effects of cocaine in rhesus monkeys by a long-acting mutant form of cocaine esterase. Neuropsychopharmacology 2011 0.98
67 Regulation of cockroach antigen-induced allergic airway hyperreactivity by the CXCR3 ligand CXCL9. J Immunol 2004 0.97
68 STAT4 signal pathways regulate inflammation and airway physiology changes in allergic airway inflammation locally via alteration of chemokines. J Immunol 2003 0.97
69 IL-17A inhibits airway reactivity induced by respiratory syncytial virus infection during allergic airway inflammation. Thorax 2013 0.97
70 The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infection. PLoS Pathog 2011 0.97
71 Effects of cocaine esterase following its repeated administration with cocaine in mice. Drug Alcohol Depend 2009 0.97
72 A key role for CC chemokine receptor 1 in T-cell-mediated respiratory inflammation. Am J Pathol 2008 0.97
73 Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen. Am J Pathol 2004 0.96
74 Deletion of CCR1 attenuates pathophysiologic responses during respiratory syncytial virus infection. J Immunol 2006 0.96
75 Autophagy-inducing protein beclin-1 in dendritic cells regulates CD4 T cell responses and disease severity during respiratory syncytial virus infection. J Immunol 2013 0.96
76 Respiratory syncytial virus-induced exaggeration of allergic airway disease is dependent upon CCR1-associated immune responses. Eur J Immunol 2005 0.95
77 Eosinophil recruitment in type-2 hypersensitivity pulmonary granulomas: source and contribution of monocyte chemotactic protein-3 (CCL7). Am J Pathol 2002 0.94
78 Respiratory virus-induced regulation of asthma-like responses in mice depends upon CD8 T cells and interferon-gamma production. Am J Pathol 2007 0.92
79 Increased responsiveness of murine eosinophils to MIP-1beta (CCL4) and TCA-3 (CCL1) is mediated by their specific receptors, CCR5 and CCR8. J Leukoc Biol 2002 0.91
80 Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation. PLoS One 2009 0.91
81 Immortalized mouse inner ear cell lines demonstrate a role for chemokines in promoting the growth of developing statoacoustic ganglion neurons. J Assoc Res Otolaryngol 2005 0.91
82 Stem cell factor attenuates liver damage in a murine model of acetaminophen-induced hepatic injury. Lab Invest 2003 0.91
83 Chronic schistosome infection leads to modulation of granuloma formation and systemic immune suppression. Front Immunol 2013 0.91
84 AMD3465, a novel CXCR4 receptor antagonist, abrogates schistosomal antigen-elicited (type-2) pulmonary granuloma formation. Am J Pathol 2006 0.90
85 Interleukin-12-independent down-modulation of cockroach antigen-induced asthma in mice by intranasal exposure to bacterial lipopolysaccharide. Am J Pathol 2003 0.90
86 Discovery of a potent nanoparticle P-selectin antagonist with anti-inflammatory effects in allergic airway disease. FASEB J 2003 0.90
87 Triggering receptor expressed on myeloid cells-1 (TREM-1) modulates immune responses to Aspergillus fumigatus during fungal asthma in mice. Immunol Invest 2011 0.90
88 Absence of CC chemokine receptor 8 enhances innate immunity during septic peritonitis. FASEB J 2005 0.89
89 Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity. J Immunol 2010 0.89
90 Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma. Respir Res 2007 0.88
91 Inefficient lymph node sensitization during respiratory viral infection promotes IL-17-mediated lung pathology. J Immunol 2010 0.88
92 TSLP promotes induction of Th2 differentiation but is not necessary during established allergen-induced pulmonary disease. PLoS One 2013 0.87
93 Role of CC chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis. Mediators Inflamm 2004 0.87
94 Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma. J Immunol 2014 0.87
95 CD8+ T cell contributions to allergen induced pulmonary inflammation and airway hyperreactivity. Eur J Immunol 2005 0.87
96 TLR3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung. Eur J Immunol 2008 0.86
97 Toll like receptor 3 plays a critical role in the progression and severity of acetaminophen-induced hepatotoxicity. PLoS One 2013 0.86
98 IPS-1 signaling has a nonredundant role in mediating antiviral responses and the clearance of respiratory syncytial virus. J Immunol 2012 0.86
99 The role of chemokines in virus-associated asthma exacerbations. Curr Allergy Asthma Rep 2008 0.86
100 Remission of chronic fungal asthma in the absence of CCR8. J Allergy Clin Immunol 2007 0.86
101 Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation. Am J Respir Crit Care Med 2009 0.86
102 Stem cell factor-mediated activation pathways promote murine eosinophil CCL6 production and survival. J Leukoc Biol 2007 0.85
103 Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating disease. J Neurovirol 2006 0.85
104 Quercetin blocks airway epithelial cell chemokine expression. Am J Respir Cell Mol Biol 2006 0.84
105 Eotaxin/CCL11 suppresses IL-8/CXCL8 secretion from human dermal microvascular endothelial cells. J Immunol 2002 0.84
106 Differential expression of retinal pigment epithelium (RPE) IP-10 and interleukin-8. Exp Eye Res 2006 0.84
107 Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration. J Leukoc Biol 2013 0.84
108 Essential role of stem cell factor-c-Kit signalling pathway in bleomycin-induced pulmonary fibrosis. J Pathol 2013 0.84
109 Differential role of IFN-gamma-inducible protein 10 kDa in a cockroach antigen-induced model of allergic airway hyperreactivity: systemic versus local effects. J Immunol 2002 0.83
110 Delta-like 4 differentially regulates murine CD4 T cell expansion via BMI1. PLoS One 2010 0.83
111 Eotaxin/CCL11 is a negative regulator of neutrophil recruitment in a murine model of endotoxemia. Exp Mol Pathol 2002 0.83
112 The chemokine receptor CCR6 is an important component of the innate immune response. Eur J Immunol 2007 0.83
113 Repeated administration of a mutant cocaine esterase: effects on plasma cocaine levels, cocaine-induced cardiovascular activity, and immune responses in rhesus monkeys. J Pharmacol Exp Ther 2012 0.83
114 STAT3-mediated IL-17 production by postseptic T cells exacerbates viral immunopathology of the lung. Shock 2012 0.82
115 IL-17A and IL-25: therapeutic targets for allergic and exacerbated asthmatic disease. Future Med Chem 2012 0.82
116 Gender Disparities in Academic Practice. Plast Reconstr Surg 2015 0.81
117 Innate immune responses to respiratory syncytial virus infection. Curr Top Microbiol Immunol 2013 0.81
118 The missing link: chemokine receptors and tissue matrix breakdown in COPD. Trends Pharmacol Sci 2006 0.79
119 The role of CCL22 (MDC) for the recruitment of eosinophils during allergic pleurisy in mice. J Leukoc Biol 2003 0.79
120 Chemokines and asthma. Sarcoidosis Vasc Diffuse Lung Dis 2003 0.79
121 Chemokine receptors: understanding their role in asthmatic disease. Immunol Allergy Clin North Am 2004 0.78
122 STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease. J Immunol 2013 0.77
123 Association of IL-13 in respiratory syncytial virus-induced pulmonary disease: still a promising target. Expert Rev Anti Infect Ther 2010 0.77
124 Eosinophil activation of fibroblasts from chronic allergen-induced disease utilizes stem cell factor for phenotypic changes. Am J Pathol 2007 0.76
125 Mice genetically lacking endothelial selectins are resistant to the lethality in septic peritonitis. Exp Mol Pathol 2002 0.76
126 Role of growth arrest-specific gene 6 in the development of fungal allergic airway disease in mice. Am J Respir Cell Mol Biol 2014 0.75