R Alan North

Author PubWeight™ 56.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 P2X receptors as cell-surface ATP sensors in health and disease. Nature 2006 4.55
2 Signaling at purinergic P2X receptors. Annu Rev Physiol 2009 3.41
3 Subunit arrangement in P2X receptors. J Neurosci 2003 1.93
4 N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors. Am J Physiol Cell Physiol 2005 1.72
5 Neuromodulation by extracellular ATP and P2X receptors in the CNS. Neuron 2012 1.70
6 Vesicular release of ATP at central synapses. Pflugers Arch 2006 1.69
7 NMDA receptors mediate neuron-to-glia signaling in mouse cortical astrocytes. J Neurosci 2006 1.69
8 New structure enlivens interest in P2X receptors. Trends Pharmacol Sci 2010 1.66
9 An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum. Nature 2007 1.66
10 Reanalysis of P2X7 receptor expression in rodent brain. J Neurosci 2004 1.64
11 Pharmacological and biophysical properties of the human P2X5 receptor. Mol Pharmacol 2003 1.44
12 Altered hippocampal synaptic potentiation in P2X4 knock-out mice. J Neurosci 2006 1.44
13 P2X7 receptor channels allow direct permeation of nanometer-sized dyes. J Neurosci 2013 1.37
14 Thr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308. J Neurosci 2007 1.34
15 Identification of a trafficking motif involved in the stabilization and polarization of P2X receptors. J Biol Chem 2004 1.25
16 P2X4, P2Y1 and P2Y2 receptors on rat alveolar macrophages. Br J Pharmacol 2003 1.25
17 Role of ectodomain lysines in the subunits of the heteromeric P2X2/3 receptor. Mol Pharmacol 2006 1.24
18 P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes. J Neurosci 2008 1.23
19 Permeation properties of a P2X receptor in the green algae Ostreococcus tauri. J Biol Chem 2008 1.22
20 A C-terminal lysine that controls human P2X4 receptor desensitization. J Biol Chem 2006 1.21
21 Polar residues in the second transmembrane domain of the rat P2X2 receptor that affect spontaneous gating, unitary conductance, and rectification. J Neurosci 2009 1.21
22 Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus. J Biol Chem 2002 1.17
23 ATP analogues with modified phosphate chains and their selectivity for rat P2X2 and P2X2/3 receptors. Br J Pharmacol 2003 1.12
24 Kv1.3 potassium channels in human alveolar macrophages. Am J Physiol Lung Cell Mol Physiol 2003 1.12
25 Quantal release of ATP in mouse cortex. J Gen Physiol 2007 1.09
26 Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopy. J Biol Chem 2008 1.08
27 Kinetics of antagonist actions at rat P2X2/3 heteromeric receptors. Br J Pharmacol 2002 1.06
28 Ectodomain lysines and suramin block of P2X1 receptors. J Biol Chem 2008 1.04
29 P2X receptor channels show threefold symmetry in ionic charge selectivity and unitary conductance. Nat Neurosci 2010 1.01
30 Pannexin 1 forms an anion-selective channel. Pflugers Arch 2012 1.00
31 Sustained depolarization and ADP-ribose activate a common ionic current in rat peritoneal macrophages. J Immunol 2003 0.93
32 Activation of trimeric P2X2 receptors by fewer than three ATP molecules. Mol Pharmacol 2012 0.92
33 Tissue distribution of P2X4 receptors studied with an ectodomain antibody. Cell Tissue Res 2003 0.91
34 Electrophysiological and morphological properties of neurons in the substantia gelatinosa of the mouse trigeminal subnucleus caudalis. Pain 2009 0.89
35 Optical control of trimeric P2X receptors and acid-sensing ion channels. Proc Natl Acad Sci U S A 2013 0.84
36 Role of P2X4 receptors in synaptic strengthening in mouse CA1 hippocampal neurons. Eur J Neurosci 2011 0.84
37 Interaction between cysteines introduced into each transmembrane domain of the rat P2X2 receptor. Br J Pharmacol 2003 0.84
38 P2X receptor intermediate activation states have altered nucleotide selectivity. J Neurosci 2013 0.83
39 Functional properties of five Dictyostelium discoideum P2X receptors. J Biol Chem 2013 0.82
40 Direct gating of ATP-activated ion channels (P2X2 receptors) by lipophilic attachment at the outer end of the second transmembrane domain. J Biol Chem 2013 0.81
41 Ectodomain movements of an ATP-gated ion channel (P2X2 receptor) probed by disulfide locking. J Biol Chem 2014 0.81
42 Spontaneous autocrine release of protons activates ASIC-mediated currents in HEK293 cells. J Cell Physiol 2007 0.79
43 Methyllycaconitine, alpha-bungarotoxin and (+)-tubocurarine block fast ATP-gated currents in rat dorsal root ganglion cells. Br J Pharmacol 2004 0.75