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Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings.

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🔗 View Article (PMID 24398881)

Published in Gut on January 07, 2014

Authors

Charlotte R Hedin1, Neil E McCarthy2, Petra Louis3, Freda M Farquharson3, Sara McCartney4, Kirstin Taylor5, Natalie J Prescott5, Trevor Murrells6, Andrew J Stagg7, Kevin Whelan8, James O Lindsay9

Author Affiliations

1: Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, UK Centre for Digestive Diseases, Blizard Institute, Queen Mary University of London, London, UK.
2: Centre for Digestive Diseases, Blizard Institute, Queen Mary University of London, London, UK.
3: Microbiology Group, Gut Health Theme, Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen, UK.
4: Department for Gastroenterology and Clinical Nutrition, University College Hospitals NHS Foundation Trust, London, UK.
5: Department of Medical and Molecular Genetics, King's College London, London, UK.
6: National Nursing Research Unit, Florence Nightingale School of Nursing and Midwifery, King's College London, London, UK.
7: Centre for Immunology and Infectious Disease, Blizard Institute, Queen Mary University of London, London, UK.
8: Diabetes and Nutritional Sciences Division, School of Medicine, King's College London, London, UK.
9: Centre for Digestive Diseases, Blizard Institute, Queen Mary University of London, London, UK Gastroenterology Division, Barts Health NHS Trust, London, UK.

Associated clinical trials:

The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives | NCT03291743

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