Published in Endocr Rev on May 01, 1987
Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol (1989) 3.48
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol Cell Biol (1992) 3.41
Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells. Proc Natl Acad Sci U S A (1989) 3.24
Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation. J Cell Biol (1988) 2.84
Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity. J Cell Biol (1990) 2.33
Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes. J Clin Invest (1990) 2.25
Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. J Clin Invest (1992) 2.19
Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J (1989) 2.14
Retinal light damage: mechanisms and protection. Prog Retin Eye Res (2009) 2.11
Distribution of basic fibroblast growth factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues. J Cell Biol (1990) 2.07
Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wounds. J Clin Invest (1989) 2.04
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell (1993) 1.97
De novo adipogenesis in mice at the site of injection of basement membrane and basic fibroblast growth factor. Proc Natl Acad Sci U S A (1998) 1.87
Expression of transforming growth factor-beta 1 is increased in human vascular restenosis lesions. J Clin Invest (1992) 1.82
Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice. J Exp Med (1990) 1.80
Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation. Proc Natl Acad Sci U S A (1988) 1.71
Duodenal ulcer. Discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann Surg (1991) 1.61
Heparanase activity expressed by platelets, neutrophils, and lymphoma cells releases active fibroblast growth factor from extracellular matrix. Cell Regul (1990) 1.55
Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites. Proc Natl Acad Sci U S A (1991) 1.55
Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner. Proc Natl Acad Sci U S A (1991) 1.52
Mathematical modeling of tumor-induced angiogenesis. J Math Biol (2004) 1.51
Growth factor expression in aorta of normotensive and hypertensive rats. J Clin Invest (1989) 1.46
Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor. J Cell Biol (1990) 1.42
Gene expression of fibroblast growth factors in human gliomas and meningiomas: demonstration of cellular source of basic fibroblast growth factor mRNA and peptide in tumor tissues. Proc Natl Acad Sci U S A (1990) 1.41
Molecules, cancer, and the surgeon. A review of molecular biology and its implications for surgical oncology. Ann Surg (1990) 1.39
Platelet-derived growth factors and fibroblast growth factors are mitogens for rat Schwann cells. J Cell Biol (1990) 1.38
Correlation of cell migration, cell invasion, receptor number, proteinase production, and basic fibroblast growth factor levels in endothelial cells. J Cell Biol (1990) 1.37
Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line. Proc Natl Acad Sci U S A (1990) 1.37
Basic fibroblast growth factor in atria and ventricles of the vertebrate heart. J Cell Biol (1989) 1.36
Acidic fibroblast growth factor mRNA is expressed by cardiac myocytes in culture and the protein is localized to the extracellular matrix. Proc Natl Acad Sci U S A (1989) 1.32
In vitro and in vivo activation of endothelial cells by colony-stimulating factors. J Clin Invest (1991) 1.31
In situ detection of basic fibroblast growth factor by highly specific antibodies. Am J Pathol (1990) 1.31
Expression of human basic fibroblast growth factor cDNA in baby hamster kidney-derived cells results in autonomous cell growth. J Cell Biol (1988) 1.25
A 20-year history of childhood HIV-associated nephropathy. Pediatr Nephrol (2004) 1.25
Retracted Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis. J Clin Invest (2002) 1.24
Detection and characterization of the fibroblast growth factor-related oncoprotein INT-2. Mol Cell Biol (1989) 1.21
Biodegradable elastomeric scaffolds with basic fibroblast growth factor release. J Control Release (2007) 1.21
Synovium-derived stem cell-based chondrogenesis. Differentiation (2008) 1.18
"Humanized" stem cell culture techniques: the animal serum controversy. Stem Cells Int (2011) 1.18
The safety and effect of topically applied recombinant basic fibroblast growth factor on the healing of chronic pressure sores. Ann Surg (1992) 1.18
Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen. J Cell Biol (1990) 1.16
Regulation of the fibroblast growth factor receptor in early Xenopus embryos. Proc Natl Acad Sci U S A (1990) 1.12
The mitogenic signaling pathway but not the plasminogen activator-inducing pathway of basic fibroblast growth factor is mediated through protein kinase C in fetal bovine aortic endothelial cells. J Cell Biol (1989) 1.10
Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications. Hum Reprod Update (2011) 1.10
Secreted or nonsecreted forms of acidic fibroblast growth factor produced by transfected epithelial cells influence cell morphology, motility, and invasive potential. Proc Natl Acad Sci U S A (1991) 1.08
Increased expression of acidic and basic fibroblast growth factors in chronic pancreatitis. Am J Pathol (1994) 1.07
Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor. J Clin Invest (1995) 1.03
Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: identification as leukemia inhibitory factor. Proc Natl Acad Sci U S A (1992) 1.00
Increased expression of fibroblast growth factors in a rabbit skeletal muscle model of exercise conditioning. J Clin Invest (1990) 0.99
Isolation, characterization, and localization of heparin-binding growth factors in the heart. J Clin Invest (1990) 0.98
Transcriptional regulation of basic fibroblast growth factor gene by p53 in human glioblastoma and hepatocellular carcinoma cells. Proc Natl Acad Sci U S A (1994) 0.98
Human mast cell basic fibroblast growth factor in pulmonary fibrotic disorders. Am J Pathol (1996) 0.97
Sequestration of basic fibroblast growth factor in the primate retinal interphotoreceptor matrix. Proc Natl Acad Sci U S A (1991) 0.94
Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs. Sci Rep (2014) 0.94
Basic fibroblast growth factor is a substrate for protein phosphorylation and is phosphorylated by capillary endothelial cells in culture. Proc Natl Acad Sci U S A (1989) 0.93
Optimising parameters for the differentiation of SH-SY5Y cells to study cell adhesion and cell migration. BMC Res Notes (2013) 0.91
Basic fibroblast growth factor regulates type I collagen and collagenase gene expression in human smooth muscle cells. Am J Pathol (1995) 0.90
Fibroblast growth factor enhances type beta 1 transforming growth factor gene expression in osteoblast-like cells. J Cell Biol (1989) 0.89
Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro. Am J Pathol (1992) 0.88
Heparin microparticle effects on presentation and bioactivity of bone morphogenetic protein-2. Biomaterials (2014) 0.88
Acidic fibroblast growth factor modulates Staphylococcus aureus adherence to human endothelial cells. Infect Immun (1988) 0.87
Cell transformation by kFGF requires secretion but not glycosylation. J Cell Biol (1991) 0.87
Anti-angiogenic action of hyperthermia by suppressing gene expression and production of tumour-derived vascular endothelial growth factor in vivo and in vitro. Br J Cancer (2002) 0.86
Safety and efficacy of sustained release of basic fibroblast growth factor using gelatin hydrogel in patients with critical limb ischemia. Heart Vessels (2015) 0.85
Possible effects of glimepiride beyond glycemic control in patients with type 2 diabetes: a preliminary report. Cardiovasc Diabetol (2014) 0.85
Differential expression of basic fibroblast growth factor (bFGF) in melanocytic lesions demonstrated by in situ hybridization. Implications for tumor progression. Am J Pathol (1994) 0.85
Fibroblast growth factor 2 induced proliferation in osteoblasts and bone marrow stromal cells: a whole cell model. Biophys J (2006) 0.84
Mediation of basic fibroblast growth factor-induced lactotropic cell proliferation by Src-Ras-mitogen-activated protein kinase p44/42 signaling. Endocrinology (2005) 0.84
Characterization of PC12 cell proliferation and differentiation-stimulated by ECM adhesion proteins and neurotrophic factors. J Mater Sci Mater Med (2003) 0.84
Characterization of release of basic fibroblast growth factor from bovine retinal endothelial cells in monolayer cultures. Biochem J (1991) 0.82
Improved airway healing using basic fibroblast growth factor in a canine tracheal autotransplantation model. Ann Surg (1998) 0.82
Basic fibroblast growth factor mRNA, bFGF peptide and FGF receptor in epiretinal membranes of intraocular proliferative disorders (PVR and PDR). Int Ophthalmol (1997) 0.82
Production of a recombinant human basic fibroblast growth factor with a collagen binding domain. Protoplasma (2001) 0.79
CD133: enhancement of bone healing by local transplantation of peripheral blood cells in a biologically delayed rat osteotomy model. PLoS One (2013) 0.79
Optimal amount of basic fibroblast growth factor in gelatin sponges incorporating β-tricalcium phosphate with chondrocytes. Tissue Eng Part A (2015) 0.79
FGF-2 promotes initial osseointegration and enhances stability of implants with low primary stability. Clin Oral Implants Res (2016) 0.78
Expression and Regulation of Transforming Growth Factor B1 in Cultured Normal and Neoplastic Rat Pituitary Cells. Endocr Pathol (1996) 0.78
Fibroblast growth factor-2 increases the renal recruitment and attachment of HIV-infected mononuclear cells to renal tubular epithelial cells. Pediatr Nephrol (2005) 0.78
Basic Fibroblast Growth Factor Expression by Two Prolactin and Thyrotropin-Producing Pituitary Adenomas. Endocr Pathol (1995) 0.78
Susceptibility towards intramolecular disulphide-bond formation affects conformational stability and folding of human basic fibroblast growth factor. Biochem J (1998) 0.78
Novel therapeutic approach for pulmonary emphysema using gelatin microspheres releasing basic fibroblast growth factor in a canine model. Surg Today (2014) 0.77
Polyomavirus middle tumor antigen increases responsiveness to growth factors. J Virol (1991) 0.77
Basic fibroblast growth factor as a selective inducer of matrix Gla protein gene expression in proliferative chondrocytes. Biochem J (2003) 0.77
Release of cell surface proteoglycans from differentiating colon cells proceeds by cleavage of lipophilic anchor peptides. Biochem J (1992) 0.77
Angiogenesis in pituitary adenomas: human studies and new mutant mouse models. Int J Endocrinol (2014) 0.77
Biochemical characterization of the molecular interaction between recombinant basic fibroblast growth factor and a recombinant soluble fibroblast growth factor receptor. Biochem J (1993) 0.77
Mast cell granule heparin proteoglycan induces lacunae in confluent endothelial cell monolayers. Am J Pathol (1999) 0.77
Exploration of the wound healing effect of topical administration of nicotine in combination with collagen scaffold in a rabbit model. J Artif Organs (2015) 0.76
Angiopoietin-1 prevents severe bleeding complications induced by heparin-like drugs and fibroblast growth factor-2 in mice. Am J Physiol Heart Circ Physiol (2015) 0.76
The expression and localization of urokinase-type plasminogen activator and its type 1 inhibitor are regulated by retinoic acid and fibroblast growth factor in human teratocarcinoma cells. Cell Regul (1991) 0.76
Expression of Growth Factors in Normal and Neoplastic Pituitary Tissues. Endocr Pathol (2000) 0.76
Purification and characterization of heparin-binding growth factors from porcine uterus. Biochem J (1990) 0.76
Accelerators of osteogenesis by recombinant human bone morphogenetic protein-2. Drug Target Insights (2007) 0.75
Amniotic fluid stem cells provide considerable advantages in epidermal regeneration: B7H4 creates a moderate inflammation microenvironment to promote wound repair. Sci Rep (2015) 0.75
Cells retrovirally transfected with fibroblast growth factor-2 isoforms exhibit altered adenylate cyclase activity and G-protein functionality. Biochem J (1996) 0.75
Involvement of basic fibroblast growth factor in suramin-induced inhibition of V79/AP4 fibroblast cell proliferation. Br J Cancer (1993) 0.75
Basic fibroblastic growth factor as a potential meningeal angiogenic factor. Skull Base Surg (1993) 0.75
De novo adipogenesis for reconstructive surgery. Cytotechnology (1999) 0.75
Vascular endothelial growth factor is a secreted angiogenic mitogen. Science (1989) 16.71
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature (1993) 15.70
Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell (1998) 10.32
Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry. Nature (1996) 9.36
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation. Nat Med (1999) 9.18
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem (1998) 8.30
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res (1997) 7.95
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science (1992) 7.49
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J Biol Chem (1991) 7.22
VEGF is required for growth and survival in neonatal mice. Development (1999) 6.16
Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins. Proc Natl Acad Sci U S A (1995) 5.92
The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol (1991) 5.61
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun (1992) 5.31
Nucleotide sequence of a bovine clone encoding the angiogenic protein, basic fibroblast growth factor. Science (1986) 5.12
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody. Proc Natl Acad Sci U S A (1996) 5.04
Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J Biol Chem (1992) 4.92
Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF. Proc Natl Acad Sci U S A (1985) 4.60
Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Nature (1974) 4.58
Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem (1994) 4.41
Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Proc Natl Acad Sci U S A (1984) 4.41
The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF. Mol Biol Cell (1993) 4.33
Purification of a fibroblast growth factor from bovine pituitary. J Biol Chem (1975) 4.25
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem (1998) 3.78
Clonal growth of bovine vascular endothelial cells: fibroblast growth factor as a survival agent. Proc Natl Acad Sci U S A (1976) 3.74
Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem (1996) 3.57
Factors involved in the modulation of cell proliferation in vivo and in vitro: the role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells. In Vitro (1978) 3.57
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis. J Clin Invest (1995) 3.52
Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature (2001) 3.42
Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions. Cancer Res (2000) 3.39
Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J (1986) 3.35
Purification of the fibroblast growth factor activity from bovine brain. J Biol Chem (1978) 3.27
Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. Nature (1987) 3.27
Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J Clin Invest (1994) 3.11
Heparin protects basic and acidic FGF from inactivation. J Cell Physiol (1986) 3.09
Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc Natl Acad Sci U S A (1993) 3.01
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J Biol Chem (1997) 2.95
Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate. Arch Ophthalmol (1996) 2.95
Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem (2000) 2.87
Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. J Biol Chem (1994) 2.87
Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth. Cancer Res (1978) 2.86
The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules. J Biol Chem (1992) 2.85
Growth factors in mammalian cell culture. Annu Rev Biochem (1976) 2.83
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci U S A (2001) 2.77
The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency. J Biol Chem (1996) 2.75
Permissive effect of the extracellular matrix on cell proliferation in vitro. Proc Natl Acad Sci U S A (1980) 2.71
Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis. J Immunol (1994) 2.66
The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature (1994) 2.49
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem Biophys Res Commun (1992) 2.47
Isolation and partial molecular characterization of pituitary fibroblast growth factor. Proc Natl Acad Sci U S A (1984) 2.46
Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state. Development (2000) 2.43
Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate. Ophthalmology (1996) 2.41
Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells. J Natl Cancer Inst (2001) 2.27
The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells. J Biol Chem (1985) 2.27
Stimulation of corneal endothelial cell proliferations in vitro by fibroblast and epidermal growth factors. Exp Eye Res (1977) 2.27
Fibroblast growth factor. Mol Cell Endocrinol (1986) 2.26
Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165 [corrected]. J Biol Chem (2000) 2.25
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun (1991) 2.25
Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. J Clin Invest (1992) 2.19
Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol (1992) 2.14
Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells. EMBO J (1989) 2.14
Characterization of novel vascular endothelial growth factor (VEGF) receptors on tumor cells that bind VEGF165 via its exon 7-encoded domain. J Biol Chem (1996) 2.12
VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix. J Biol Chem (1997) 2.12
Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc Natl Acad Sci U S A (1993) 2.09
VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain. J Clin Invest (1999) 2.08
A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF. Oncogene (1995) 2.07
Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J Clin Invest (1993) 2.07
Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimal hyperplasia in balloon-injured rat carotid artery. Circulation (1995) 2.07
Characterization of the receptors for vascular endothelial growth factor. J Biol Chem (1990) 2.06
The angiogenic activity of the fibroblast and epidermal growth factor. Exp Eye Res (1979) 2.06
Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin. J Cell Biol (1978) 2.06
Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo. Prostate (1998) 2.02
Complete inhibition of rhabdomyosarcoma xenograft growth and neovascularization requires blockade of both tumor and host vascular endothelial growth factor. Cancer Res (2000) 2.02
Basic and acidic fibroblast growth factors interact with the same cell surface receptors. J Biol Chem (1986) 2.01
Angiogenesis and bone growth. Trends Cardiovasc Med (2000) 1.98
Morphological appearance, growth behavior and migratory activity of human tumor cells maintained on extracellular matrix versus plastic. Cell (1980) 1.94
Extracellular matrix and control of proliferation of vascular endothelial cells. J Clin Invest (1980) 1.93
Growth control in cultured mouse fibroblasts: induction of the pleiotypic and mitogenic responses by a purified growth factor. Proc Natl Acad Sci U S A (1974) 1.93
Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation (1995) 1.92
Vascular endothelial growth factor: a new member of the platelet-derived growth factor gene family. Biochem Biophys Res Commun (1989) 1.91
Comparisons of the intraocular tissue distribution, pharmacokinetics, and safety of 125I-labeled full-length and Fab antibodies in rhesus monkeys following intravitreal administration. Toxicol Pathol (1999) 1.90
Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization. Am J Pathol (1998) 1.90
Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro. J Biol Chem (1998) 1.89
Identification, localization, and role of fibronectin in cultured bovine endothelial cells. Proc Natl Acad Sci U S A (1978) 1.89
Characterization of a factor that promotes neurite outgrowth: evidence linking activity to a heparan sulfate proteoglycan. J Cell Biol (1982) 1.88
Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy. Cancer Res (1996) 1.86
The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors (1992) 1.84
Hypoxic induction of endothelial cell growth factors in retinal cells: identification and characterization of vascular endothelial growth factor (VEGF) as the mitogen. Mol Med (1995) 1.78
Molecular and biological characterization of fibroblast growth factor, an angiogenic factor which also controls the proliferation and differentiation of mesoderm and neuroectoderm derived cells. Cell Differ (1986) 1.75
High level of physical activity preserves the cardioprotective effect of preinfarction angina in elderly patients. J Am Coll Cardiol (2001) 1.75
Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis. J Biol Chem (1996) 1.73
Frailty predicts long-term mortality in elderly subjects with chronic heart failure. Eur J Clin Invest (2005) 1.68