S H Speck

Author PubWeight™ 127.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Complete sequence and genomic analysis of murine gammaherpesvirus 68. J Virol 1997 7.71
2 Macrophages are the major reservoir of latent murine gammaherpesvirus 68 in peritoneal cells. J Virol 1999 4.12
3 Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1. J Virol 1990 4.09
4 Mature B cells are required for acute splenic infection, but not for establishment of latency, by murine gammaherpesvirus 68. J Virol 1996 4.02
5 Murine gamma-herpesvirus 68 causes severe large-vessel arteritis in mice lacking interferon-gamma responsiveness: a new model for virus-induced vascular disease. Nat Med 1997 3.40
6 Analysis of the transcript encoding the latent Epstein-Barr virus nuclear antigen I: a potentially polycistronic message generated by long-range splicing of several exons. Proc Natl Acad Sci U S A 1985 3.35
7 Promoter switching in Epstein-Barr virus during the initial stages of infection of B lymphocytes. Proc Natl Acad Sci U S A 1990 3.29
8 Identification of phorbol ester response elements in the promoter of Epstein-Barr virus putative lytic switch gene BZLF1. J Virol 1990 3.09
9 Mutually exclusive use of viral promoters in Epstein-Barr virus latently infected lymphocytes. Proc Natl Acad Sci U S A 1989 2.88
10 Influence of Burkitt's lymphoma and primary B cells on latent gene expression by the nonimmortalizing P3J-HR-1 strain of Epstein-Barr virus. J Virol 1989 2.86
11 B cells regulate murine gammaherpesvirus 68 latency. J Virol 1999 2.79
12 An Epstein-Barr virus transcript from a latently infected, growth-transformed B-cell line encodes a highly repetitive polypeptide. Proc Natl Acad Sci U S A 1986 2.66
13 E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product. Proc Natl Acad Sci U S A 1993 2.61
14 Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice. J Virol 1999 2.56
15 Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection. Proc Natl Acad Sci U S A 1991 2.54
16 Exclusive expression of Epstein-Barr virus nuclear antigen 1 in Burkitt lymphoma arises from a third promoter, distinct from the promoters used in latently infected lymphocytes. Proc Natl Acad Sci U S A 1991 2.40
17 Disruption of the murine gammaherpesvirus 68 M1 open reading frame leads to enhanced reactivation from latency. J Virol 2000 2.33
18 Unraveling immunity to gamma-herpesviruses: a new model for understanding the role of immunity in chronic virus infection. Curr Opin Immunol 1999 2.19
19 Identification of critical cis elements involved in mediating Epstein-Barr virus nuclear antigen 2-dependent activity of an enhancer located upstream of the viral BamHI C promoter. J Virol 1992 2.09
20 The murine gammaherpesvirus 68 v-cyclin is a critical regulator of reactivation from latency. J Virol 2000 2.01
21 Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines. Proc Natl Acad Sci U S A 1995 1.89
22 Identification of a gammaherpesvirus selective chemokine binding protein that inhibits chemokine action. J Virol 2000 1.86
23 Characterization of gammaherpesvirus 68 gene 50 transcription. J Virol 2000 1.84
24 Cyclosporin A-sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member. EMBO J 1997 1.82
25 Evidence for coiled-coil dimer formation by an Epstein-Barr virus transactivator that lacks a heptad repeat of leucine residues. Proc Natl Acad Sci U S A 1990 1.79
26 Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis. J Virol 1991 1.79
27 Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease. Nat Med 2000 1.76
28 oriP is essential for EBNA gene promoter activity in Epstein-Barr virus-immortalized lymphoblastoid cell lines. J Virol 1996 1.67
29 ZEBRA and a Fos-GCN4 chimeric protein differ in their DNA-binding specificities for sites in the Epstein-Barr virus BZLF1 promoter. J Virol 1991 1.56
30 Characterization of the Epstein-Barr virus BZLF1 protein transactivation domain. J Virol 1992 1.54
31 Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein. J Virol 1999 1.52
32 Murine gammaherpesvirus 68 encodes a functional regulator of complement activation. J Virol 1999 1.51
33 Complex transcription of the Epstein-Barr virus BamHI fragment H rightward open reading frame 1 (BHRF1) in latently and lytically infected B lymphocytes. Proc Natl Acad Sci U S A 1988 1.47
34 Definition of cytochrome c binding domains by chemical modification: kinetics of reaction with beef mitochondrial reductase and functional organization of the respiratory chain. Proc Natl Acad Sci U S A 1979 1.44
35 The murine gammaherpesvirus 68 v-cyclin gene is an oncogene that promotes cell cycle progression in primary lymphocytes. J Virol 1999 1.42
36 Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos. J Virol 1990 1.41
37 IFN-gamma action in the media of the great elastic arteries, a novel immunoprivileged site. J Clin Invest 2001 1.39
38 Alternative splicing dictates translational start in Epstein-Barr virus transcripts. EMBO J 1990 1.38
39 Isolation and characterization of cDNA clones corresponding to transcripts from the BamHI H and F regions of the Epstein-Barr virus genome. J Virol 1987 1.34
40 Identification and mapping of polypeptides encoded by the P3HR-1 strain of Epstein-Barr virus. Proc Natl Acad Sci U S A 1984 1.31
41 Host-cell-determined methylation of specific Epstein-Barr virus promoters regulates the choice between distinct viral latency programs. Mol Cell Biol 1997 1.28
42 Identification of a negative cis element within the ZII domain of the Epstein-Barr virus lytic switch BZLF1 gene promoter. J Virol 1998 1.28
43 Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals. J Virol 1999 1.28
44 Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage. J Virol 2000 1.26
45 DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities. Mol Cell Biol 1994 1.25
46 The Epstein-Barr virus BamHI F promoter is an early lytic promoter: lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell lines. J Virol 1995 1.24
47 Regulation of the BZLF1 promoter of Epstein-Barr virus by second messengers in anti-immunoglobulin-treated B cells. Virology 1994 1.24
48 Characterization of the ZI domains in the Epstein-Barr virus BZLF1 gene promoter: role in phorbol ester induction. J Virol 1996 1.22
49 Characterization of a cDNA clone corresponding to a transcript from the Epstein-Barr virus BamHI M fragment: evidence for overlapping mRNAs. J Virol 1987 1.18
50 The reaction of primate cytochromes c with cytochrome c oxidase. Analysis of the polarographic assay. J Biol Chem 1983 1.18
51 Binding of the ubiquitous cellular transcription factors Sp1 and Sp3 to the ZI domains in the Epstein-Barr virus lytic switch BZLF1 gene promoter. Virology 1997 1.18
52 Regulation of EBNA gene transcription in lymphoblastoid cell lines: characterization of sequences downstream of BCR2 (Cp). J Virol 1997 1.16
53 Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency. Mol Cell Biol 1997 1.16
54 B-cell lines immortalized with an Epstein-Barr virus mutant lacking the Cp EBNA2 enhancer are biased toward utilization of the oriP-proximal EBNA gene promoter Wp1. J Virol 1997 1.12
55 Determining the role of the Epstein-Barr virus Cp EBNA2-dependent enhancer during the establishment of latency by using mutant and wild-type viruses recovered from cottontop marmoset lymphoblastoid cell lines. J Virol 2000 1.04
56 Cyclosporin A and FK506 block induction of the Epstein-Barr virus lytic cycle by anti-immunoglobulin. Virology 1995 1.04
57 A simple reverse transcriptase PCR assay to distinguish EBNA1 gene transcripts associated with type I and II latency from those arising during induction of the viral lytic cycle. J Virol 1996 1.03
58 Transcription of the Epstein-Barr virus nuclear antigen 1 (EBNA1) gene occurs before induction of the BCR2 (Cp) EBNA gene promoter during the initial stages of infection in B cells. J Virol 1996 1.03
59 Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells. Proc Natl Acad Sci U S A 1992 1.03
60 The Epstein-Barr virus-induced Ca2+/calmodulin-dependent kinase type IV/Gr promotes a Ca(2+)-dependent switch from latency to viral replication. J Virol 1997 1.01
61 Characterization of the deletion and rearrangement in the BamHI C region of the X50-7 Epstein-Barr virus genome, a mutant viral strain which exhibits constitutive BamHI W promoter activity. J Virol 1992 0.99
62 Epstein-Barr virus transformation. Prog Nucleic Acid Res Mol Biol 1987 0.98
63 Single catalytic site model for the oxidation of ferrocytochrome c by mitochondrial cytochrome c oxidase. Proc Natl Acad Sci U S A 1984 0.94
64 Characterization of the interaction of cytochrome c and mitochondrial ubiquinol-cytochrome c reductase. J Biol Chem 1984 0.92
65 Epstein-Barr virus in B lymphocytes: viral gene expression and function in latency. Adv Cancer Res 1992 0.89
66 Copper electron-nuclear double resonance of cytochrome c oxidase. Proc Natl Acad Sci U S A 1980 0.88
67 Bidirectional transcription of the Epstein-Barr virus major internal repeat. J Virol 1990 0.85
68 Interaction of cytochrome c with the blue copper proteins, plastocyanin and azurin. J Biol Chem 1983 0.84
69 Role of phospholipid in the low affinity reactions between cytochrome c and cytochrome oxidase. FEBS Lett 1983 0.83
70 The presteady state reaction of chemically modified cytochromes c with cytochrome oxidase. J Biol Chem 1983 0.82
71 Preferred sites for electron transfer between cytochrome c and iron and cobalt complexes. J Biol Chem 1983 0.80
72 Definition of cytochrome c binding domains by chemical modification. Interaction of horse cytochrome c with beef sulfite oxidase and analysis of steady state kinetics. J Biol Chem 1981 0.77
73 Site-specific anti-cytochrome c antibodies. Inhibition of the reactions between cytochrome c and its respiratory chain electron exchange partners. J Biol Chem 1979 0.75