Comprehensive evaluation of the anti-angiogenic and anti-neoplastic effects of Endostar on liver cancer through optical molecular imaging.

PubWeight™: 0.75‹?›

🔗 View Article (PMC 3885728)

Published in PLoS One on January 08, 2014

Authors

Qian Zhang1, Yang Du2, Zhenwen Xue2, Chongwei Chi2, Xiaohua Jia2, Jie Tian1

Author Affiliations

1: School of Life Sciences and Technology, Xidian University, Xi'an, Shaanxi, China ; Institute of Automation, Chinese Academy of Sciences, Beijing, China.
2: Institute of Automation, Chinese Academy of Sciences, Beijing, China.

Articles cited by this

Global cancer statistics. CA Cancer J Clin (2011) 185.92

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell (1997) 13.94

Primary liver cancer: worldwide incidence and trends. Gastroenterology (2004) 11.21

Role of angiogenesis in tumor growth and metastasis. Semin Oncol (2002) 9.77

Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res (2006) 6.66

Tumor angiogenesis: molecular pathways and therapeutic targets. Nat Med (2011) 4.91

Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic. Invest New Drugs (1999) 4.32

Molecular imaging in drug development. Nat Rev Drug Discov (2008) 4.06

Multimodality molecular imaging of tumor angiogenesis. J Nucl Med (2008) 3.99

Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia (2001) 2.97

Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Rev (1999) 2.83

Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action. Exp Cell Res (2005) 2.62

Angiogenesis and hepatocellular carcinoma. J Hepatol (2004) 2.25

Orthotopic models of cancer for preclinical drug evaluation: advantages and disadvantages. Eur J Cancer (2004) 2.20

Optical and multimodality molecular imaging: insights into atherosclerosis. Arterioscler Thromb Vasc Biol (2009) 1.84

A novel software platform for medical image processing and analyzing. IEEE Trans Inf Technol Biomed (2008) 1.72

Whole-animal imaging: The whole picture. Nature (2010) 1.57

Validation of luminescent source reconstruction using single-view spectrally resolved bioluminescence images. Appl Opt (2007) 1.27

Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model. Hepatology (2011) 1.23

Cone beam micro-CT system for small animal imaging and performance evaluation. Int J Biomed Imaging (2009) 1.07

Chapter 7. Molecular imaging of tumor vasculature. Methods Enzymol (2008) 1.04

Endostar induces apoptotic effects in HUVECs through activation of caspase-3 and decrease of Bcl-2. Anticancer Res (2009) 1.00

A fast reconstruction algorithm for fluorescence molecular tomography with sparsity regularization. Opt Express (2010) 0.98

Regression of established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic murine model. Hepatology (2012) 0.93

Tumor suppression by p53 is mediated in part by the antiangiogenic activity of endostatin and tumstatin. Sci STKE (2006) 0.93

Endostar, a recombined humanized endostatin, inhibits lymphangiogenesis and lymphatic metastasis of Lewis lung carcinoma xenograft in mice. Thorac Cardiovasc Surg (2011) 0.89

Dual-modality monitoring of tumor response to cyclophosphamide therapy in mice with bioluminescence imaging and small-animal positron emission tomography. Mol Imaging (2011) 0.87

Adaptive regularized method based on homotopy for sparse fluorescence tomography. Appl Opt (2013) 0.84

Endostar, a recently introduced recombinant human endostatin, inhibits proliferation and migration through regulating growth factors, adhesion factors and inflammatory mediators in choroid-retinal endothelial cells. Mol Biol (Mosk) (2010) 0.81

Evaluation of the therapeutic efficacy of a VEGFR2-blocking antibody using sodium-iodide symporter molecular imaging in a tumor xenograft model. Nucl Med Biol (2010) 0.81

Efficient reconstruction method for L1 regularization in fluorescence molecular tomography. Appl Opt (2010) 0.81

Real-time bioluminescence and tomographic imaging of gastric cancer in a novel orthotopic mouse model. Oncol Rep (2012) 0.77