Mortality and its predictors among antiretroviral therapy naïve HIV-infected individuals with CD4 cell count ≥350 cells/mm(3) compared to the general population: data from a population-based prospective HIV cohort in Uganda.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 3895200)

Published in Glob Health Action on January 15, 2014

Authors

Ben Masiira1, Kathy Baisley2, Billy N Mayanja3, Patrick Kazooba3, Dermot Maher3, Pontiano Kaleebu4

Author Affiliations

1: MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda; ben.masiira@mrcuganda.org.
2: Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
3: MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.
4: MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda; Tropical Epidemiology Group, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.

Associated clinical trials:

Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) (ADEPTT) | NCT03302299

Articles cited by this

Effect of early versus deferred antiretroviral therapy for HIV on survival. N Engl J Med (2009) 19.90

Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection. Ann Intern Med (1997) 16.44

Decline in the AIDS and death rates in the EuroSIDA study: an observational study. Lancet (2003) 7.94

Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in Malawi. Lancet (2008) 5.93

HIV-infected adults with a CD4 cell count greater than 500 cells/mm3 on long-term combination antiretroviral therapy reach same mortality rates as the general population. J Acquir Immune Defic Syndr (2007) 3.38

Effective therapy has altered the spectrum of cause-specific mortality following HIV seroconversion. AIDS (2006) 3.23

Can highly active antiretroviral therapy reduce the spread of HIV?: A study in a township of South Africa. J Acquir Immune Defic Syndr (2004) 3.19

All-cause mortality in treated HIV-infected adults with CD4 ≥500/mm3 compared with the general population: evidence from a large European observational cohort collaboration. Int J Epidemiol (2011) 2.80

Community engagement in health research: two decades of experience from a research project on HIV in rural Uganda. Trop Med Int Health (2009) 2.33

Mortality associated with HIV infection in rural Rakai District, Uganda. AIDS (2000) 2.15

Death rates in HIV-positive antiretroviral-naive patients with CD4 count greater than 350 cells per microL in Europe and North America: a pooled cohort observational study. Lancet (2010) 1.69

Successes, challenges, and limitations of current antiretroviral therapy in low-income and middle-income countries. Lancet Infect Dis (2009) 1.64

AIDS and non-AIDS morbidity and mortality across the spectrum of CD4 cell counts in HIV-infected adults before starting antiretroviral therapy in Cote d'Ivoire. Clin Infect Dis (2012) 1.64

An HIV-1 natural history cohort and survival times in rural Uganda. AIDS (1997) 1.56

HIV-1 incidence and HIV-1-associated mortality in a rural Ugandan population cohort. AIDS (1994) 1.53

Predictors of mortality among HIV infected patients taking antiretroviral treatment in Ethiopia: a retrospective cohort study. AIDS Res Ther (2012) 1.50

The general population cohort in rural south-western Uganda: a platform for communicable and non-communicable disease studies. Int J Epidemiol (2013) 1.48

HIV-1 disease progression and mortality before the introduction of highly active antiretroviral therapy in rural Uganda. AIDS (2007) 1.41

Predictors of 5-year mortality in HIV-infected adults starting highly active antiretroviral therapy in Thailand. J Acquir Immune Defic Syndr (2012) 1.18

Immunodeficiency and the risk of death in HIV infection. JAMA (1992) 1.17

Predictors of mortality in a cohort of HIV-1-infected adults in rural Africa. J Acquir Immune Defic Syndr (2007) 1.17

Rationing antiretroviral therapy in Africa--treating too few, too late. N Engl J Med (2009) 1.02

Generalizability of population-based studies on AIDS: a comparison of newly and continuously surveyed villages in rural southwest Uganda. Int J Epidemiol (2002) 0.96

HIV morbidity and mortality in Jamaica: analysis of national surveillance data, 1993--2005. Int J Infect Dis (2007) 0.94

CD4-specific mortality rates among HIV-infected adults with high CD4 counts and no antiretroviral treatment in West Africa. J Acquir Immune Defic Syndr (2012) 0.89

Pre-AIDS mortality and its association with HIV disease progression in haemophilic men, injecting drug users and homosexual men. AIDS (2000) 0.87