G I Byrne

Author PubWeight™ 103.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis. Microbiol Rev 1994 4.94
2 Induction of tryptophan catabolism is the mechanism for gamma-interferon-mediated inhibition of intracellular Chlamydia psittaci replication in T24 cells. Infect Immun 1986 4.34
3 Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro. Proc Natl Acad Sci U S A 1993 4.28
4 Parasite-specified phagocytosis of Chlamydia psittaci and Chlamydia trachomatis by L and HeLa cells. Infect Immun 1978 4.26
5 Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice. Infect Immun 1997 3.12
6 Requirements for ingestion of Chlamydia psittaci by mouse fibroblasts (L cells). Infect Immun 1976 3.11
7 Lymphokine-mediated inhibition of Chlamydia replication in mouse fibroblasts is neutralized by anti-gamma interferon immunoglobulin. Infect Immun 1983 2.77
8 Immediate toxicity of high multiplicities of Chlamydia psittaci for mouse fibroblasts (L cells). Infect Immun 1976 2.76
9 Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence. Infect Immun 1994 2.58
10 A role in vivo for tumor necrosis factor alpha in host defense against Chlamydia trachomatis. Infect Immun 1990 2.55
11 Repeated and persistent infection with Chlamydia and the development of chronic inflammation and disease. Trends Microbiol 1994 2.54
12 Lymphokine-mediated microbistatic mechanisms restrict Chlamydia psittaci growth in macrophages. J Immunol 1982 2.40
13 Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice. Infect Immun 1988 2.30
14 Effect of interferon on the growth of Chlamydia trachomatis in mouse fibroblasts (L cells). Infect Immun 1983 2.17
15 Kinetics of phagocytosis of Chlamydia psittaci by mouse fibroblasts (L cells): separation of the attachment and ingestion stages. Infect Immun 1978 1.94
16 Lymphokine enhances oxygen-independent activity against intracellular pathogens. J Exp Med 1983 1.93
17 Cellular oxidation of low-density lipoprotein by Chlamydia pneumoniae. J Infect Dis 1999 1.79
18 Interferon-induced indoleamine 2,3-dioxygenase activity inhibits Chlamydia psittaci replication in human macrophages. J Interferon Res 1989 1.74
19 Induction of tryptophan degradation in vitro and in vivo: a gamma-interferon-stimulated activity. J Interferon Res 1986 1.70
20 Biologic-response-modifier-induced indoleamine 2,3-dioxygenase activity in human peripheral blood mononuclear cell cultures. J Immunol 1987 1.65
21 Reactivation of persistent Chlamydia trachomatis infection in cell culture. Infect Immun 1995 1.54
22 Tumor necrosis factor alpha is a cytotoxin induced by murine Chlamydia trachomatis infection. Infect Immun 1989 1.54
23 IFN-gamma-mediated antimicrobial response. Indoleamine 2,3-dioxygenase-deficient mutant host cells no longer inhibit intracellular Chlamydia spp. or Toxoplasma growth. J Immunol 1993 1.53
24 Inhibition of Chlamydia psittaci in oxidatively active thioglycolate-elicited macrophages: distinction between lymphokine-mediated oxygen-dependent and oxygen-independent macrophage activation. Infect Immun 1983 1.53
25 Characterization of low-density lipoprotein uptake by murine macrophages exposed to Chlamydia pneumoniae. Microbes Infect 1999 1.52
26 Cytochalasin B does not inhibit ingestion of Chlamydia psittaci by mouse fibroblasts (L cells) and mouse peritoneal macrophages. Infect Immun 1979 1.48
27 T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring. Clin Exp Immunol 1996 1.48
28 Induction of macrophage foam cell formation by Chlamydia pneumoniae. J Infect Dis 1998 1.46
29 Interferon-induced indoleamine 2,3-dioxygenase activity in human mononuclear phagocytes. J Leukoc Biol 1989 1.41
30 Immunoelectron-microscopic quantitation of differential levels of chlamydial proteins in a cell culture model of persistent Chlamydia trachomatis infection. Infect Immun 1994 1.41
31 Interferons and indoleamine 2,3-dioxygenase: role in antimicrobial and antitumor effects. Experientia 1989 1.33
32 Chlamydia trachomatis persistence in the female mouse genital tract: inducible nitric oxide synthase and infection outcome. Infect Immun 2001 1.28
33 Arrays of hemispheric surface projections on Chlamydia psittaci and Chlamydia trachomatis observed by scanning electron microscopy. J Bacteriol 1979 1.26
34 Prior genital tract infection with a murine or human biovar of Chlamydia trachomatis protects mice against heterotypic challenge infection. Infect Immun 1999 1.25
35 A Chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharide. Infect Immun 1998 1.25
36 Beta interferon inhibits Toxoplasma gondii growth in human monocyte-derived macrophages. Infect Immun 1989 1.20
37 Reactivation of chlamydial genital tract infection in mice. Infect Immun 1997 1.17
38 Role for inducible nitric oxide synthase in protection from chronic Chlamydia trachomatis urogenital disease in mice and its regulation by oxygen free radicals. Infect Immun 2001 1.15
39 Inducible nitric oxide synthase does not affect resolution of murine chlamydial genital tract infections or eradication of chlamydiae in primary murine cell culture. Infect Immun 1998 1.14
40 Effect of interferon on a primary conjunctival epithelial cell model of trachoma. Invest Ophthalmol Vis Sci 1991 1.11
41 Cytokine-mediated indoleamine 2,3-dioxygenase induction in response to Chlamydia infection in human macrophage cultures. Infect Immun 1994 1.10
42 In vitro expression of factor-mediated cytotoxic activity generated during the immune response to Chlamydia in the mouse. J Immunol 1985 1.07
43 Differential susceptibility of chlamydiae to exogenous fibroblast interferon. Infect Immun 1983 1.07
44 Chlamydial heat shock proteins and disease pathology: new paradigms for old problems? Infect Dis Obstet Gynecol 1999 1.04
45 Seroreactivity to Chlamydia trachomatis Hsp10 correlates with severity of human genital tract disease. Infect Immun 2000 1.04
46 Interactions between macrophages and chlamydiae. Immunol Ser 1994 0.99
47 Intracellular tryptophan pool sizes may account for differences in gamma interferon-mediated inhibition and persistence of chlamydial growth in polarized and nonpolarized cells. Infect Immun 1999 0.99
48 Use of monoclonal antibodies to facilitate identification, cloning, and purification of Chlamydia trachomatis hsp10. J Clin Microbiol 1997 0.97
49 Upregulation of interferon-induced indoleamine 2,3-dioxygenase in human macrophage cultures by lipopolysaccharide, muramyl tripeptide, and interleukin-1. Cell Immunol 1995 0.95
50 Chlamydial virulence determinants in atherogenesis: the role of chlamydial lipopolysaccharide and heat shock protein 60 in macrophage-lipoprotein interactions. J Infect Dis 2000 0.92
51 Immunity to Chlamydia: comparison of human infections and murine models. Res Immunol 1997 0.92
52 Interferon gamma induced production of indoleamine 2,3 dioxygenase in cultured human synovial cells. J Rheumatol 1994 0.90
53 Effects of interferons beta or gamma on neopterin biosynthesis and tryptophan degradation by human alveolar macrophages in vitro: synergy with lipopolysaccharide. Am J Respir Cell Mol Biol 1992 0.90
54 Chlamydia pneumoniae-infected monocytes exhibit increased adherence to human aortic endothelial cells. Microbes Infect 2001 0.89
55 Role of tryptophan in gamma interferon-mediated chlamydial persistence. Ann N Y Acad Sci 1994 0.84
56 Differential effects of gamma interferon on Chlamydia trachomatis growth in polarized and nonpolarized human epithelial cells in culture. Infect Immun 1998 0.83
57 Chlamydial treatment failures: a persistent problem? J Eur Acad Dermatol Venereol 2001 0.80
58 In vivo-activated mononuclear phagocytes and protective immunity to chlamydiae in mice. Infect Immun 1988 0.80
59 Interferons: from virus inhibitor to modulator of amino acid and lipid metabolism. J Interferon Res 1987 0.79
60 Inducible nitric oxide synthase regulates production of isoprostanes in vivo during chlamydial genital infection in mice. Infect Immun 2003 0.79
61 Differential modulation of lymphocyte proliferative responses and lymphokine secretion in mice during development of immunity to Chlamydia psittaci. Infect Immun 1989 0.79
62 Tryptophan metabolism in chronic inflammatory lung disease. J Lab Clin Med 1995 0.78
63 Lymphokine stimulated macrophages inhibit intracellular Chlamydia psittaci replication by mechanisms distinct from intracellular inhibition of Toxoplasma gondii replication. Adv Exp Med Biol 1983 0.77
64 The effect of intracellular Chlamydia psittaci on lysosomal enzyme activities in mouse peritoneal macrophages. Acta Pathol Microbiol Immunol Scand C 1987 0.76
65 Effects of combinations of interferon-beta ser and interferon-gamma on interferon-inducible proteins and on the cell cycle. J Biol Response Mod 1990 0.75
66 The challenge of defining disease. Science 2001 0.75
67 Enhancement of indoleamine 2,3-dioxygenase activity in cancer patients receiving interferon-beta Ser. J Interferon Res 1989 0.75