β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma.

PubWeight™: 0.82‹?›

🔗 View Article (PMC 4170118)

Published in Mol Pharmacol on January 22, 2014

Authors

Ian C Clift1, Adebowale O Bamidele, Christie Rodriguez-Ramirez, Kimberly N Kremer, Karen E Hedin

Author Affiliations

1: Neurobiology of Disease (I.C.C.), Molecular Pharmacology and Experimental Therapeutics (A.O.B.), and Department of Immunology (C.R.-R., K.N.K., K.E.H.), Mayo Clinic College of Medicine, Mayo Graduate School, Mayo Clinic, Rochester, Minnesota.

Articles cited by this

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (2010) 10.30

The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature (1998) 7.38

Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J Cell Biol (1989) 6.76

The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci (2002) 5.04

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction. Science (2000) 4.61

Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol (2008) 4.04

The chemokine superfamily revisited. Immunity (2012) 2.83

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research. Neurotoxicology (2008) 2.45

A review on CXCR4/CXCL12 axis in oncology: no place to hide. Eur J Cancer (2012) 2.39

Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification. J Cell Biol (1993) 2.36

A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma. J Immunol (2001) 2.33

Agonist-selective mechanisms of GPCR desensitization. Br J Pharmacol (2007) 2.17

Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J Biol Chem (2010) 2.06

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization. J Biol Chem (1999) 2.05

CXCR4 physically associates with the T cell receptor to signal in T cells. Immunity (2006) 2.01

Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization. J Biol Chem (1997) 1.98

Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. J Biol Chem (2007) 1.98

Chemokines and their receptors in the central nervous system. Front Neuroendocrinol (2001) 1.93

A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture. J Natl Cancer Inst (1976) 1.82

The AMD3100 story: the path to the discovery of a stem cell mobilizer (Mozobil). Biochem Pharmacol (2008) 1.70

beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4. J Biol Chem (2000) 1.67

A role for CXCR4 signaling in survival and migration of neural and oligodendrocyte precursors. Glia (2005) 1.51

Role of the intracellular domains of CXCR4 in SDF-1-mediated signaling. Blood (2002) 1.45

Correlation effect of EGFR and CXCR4 and CCR7 chemokine receptors in predicting breast cancer metastasis and prognosis. J Exp Clin Cancer Res (2010) 1.44

The blood-brain barrier, chemokines and multiple sclerosis. Biochim Biophys Acta (2010) 1.40

TCR trafficking in resting and stimulated T cells. Crit Rev Immunol (2004) 1.34

Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4. Mol Biol Cell (2010) 1.32

CXC chemokine receptor 4 regulates neuronal migration and axonal pathfinding in the developing nervous system: implications for neuronal regeneration in the adult brain. J Mol Endocrinol (2007) 1.30

An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons. J Alzheimers Dis (2010) 1.28

Phospholipase cbeta is critical for T cell chemotaxis. J Immunol (2007) 1.22

CXCR4 expression in neuroblastoma primary tumors is associated with clinical presentation of bone and bone marrow metastases. J Pediatr Surg (2004) 1.12

Gα13 and Rho mediate endosomal trafficking of CXCR4 into Rab11+ vesicles upon stromal cell-derived factor-1 stimulation. J Immunol (2010) 1.10

The chemokine receptor CXCR4 strongly promotes neuroblastoma primary tumour and metastatic growth, but not invasion. PLoS One (2007) 1.09

The role of cytokine receptor signaling in lymphocyte development. Curr Opin Immunol (1999) 1.07

The interaction of phospholipase C-beta3 with Shank2 regulates mGluR-mediated calcium signal. J Biol Chem (2005) 1.05

CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation. Mol Cancer (2009) 1.01

Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma. PLoS One (2012) 0.98

MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas. FASEB J (2011) 0.98

Neuroblastoma. Semin Pediatr Surg (2012) 0.97

CXCR4 signaling regulates remyelination by endogenous oligodendrocyte progenitor cells in a viral model of demyelination. Glia (2011) 0.96

G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4. Biochemistry (2011) 0.96

Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization. J Neurovirol (2006) 0.95

Gene profiling of high risk neuroblastoma. World J Surg (2005) 0.94

G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling. Cardiovasc Res (2010) 0.94

Cutaneous T-cell lymphoma: roles for chemokines and chemokine receptors. J Invest Dermatol (2009) 0.94

Chemokines in neuroectodermal tumour progression and metastasis. Semin Cancer Biol (2008) 0.93

CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak. J Biol Chem (2013) 0.93

Site-specific metastasis formation: chemokines as regulators of tumor cell adhesion, motility and invasion. Cell Adh Migr (2009) 0.92

G protein-coupled receptor kinases 3 and 6 use different pathways to desensitize the endogenous M3 muscarinic acetylcholine receptor in human SH-SY5Y cells. Mol Pharmacol (2001) 0.92

Neuroblastoma therapy: what is in the pipeline? Endocr Relat Cancer (2011) 0.92

C-terminal di-leucine motif of dopamine D₁ receptor plays an important role in its plasma membrane trafficking. PLoS One (2011) 0.92

Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors. Semin Cancer Biol (2008) 0.90

Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses. J Immunol (2011) 0.86

Comprehensive cytogenomic profile of the in vitro neuronal model SH-SY5Y. Neurogenetics (2012) 0.84

Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma. Pediatr Blood Cancer (2011) 0.84

Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway. Cell Signal (2010) 0.84

Establishment and characterization of xenograft models of human neuroblastoma bone metastasis. Childs Nerv Syst (2012) 0.81

Protective effects of 27- and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells. Neurosci Lett (2012) 0.80

Human embryonal carcinoma cells express low levels of functional receptor for epidermal growth factor. Exp Cell Res (1985) 0.77

Articles by these authors

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood (2007) 2.76

CXCR4 physically associates with the T cell receptor to signal in T cells. Immunity (2006) 2.01

Gα13 and Rho mediate endosomal trafficking of CXCR4 into Rab11+ vesicles upon stromal cell-derived factor-1 stimulation. J Immunol (2010) 1.10

Expression of the chemokine receptors CXCR4 and CCR7 and disease progression in B-cell chronic lymphocytic leukemia/ small lymphocytic lymphoma. Mayo Clin Proc (2004) 1.08

Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine. J Immunol (2003) 1.02

CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak. J Biol Chem (2013) 0.93

Haplotype-independent costimulation of IL-10 secretion by SDF-1/CXCL12 proceeds via AP-1 binding to the human IL-10 promoter. J Immunol (2007) 0.90

Stromal cell-derived factor-1 signaling via the CXCR4-TCR heterodimer requires phospholipase C-β3 and phospholipase C-γ1 for distinct cellular responses. J Immunol (2011) 0.86

G alpha i2 and ZAP-70 mediate RasGRP1 membrane localization and activation of SDF-1-induced T cell functions. J Immunol (2011) 0.83

Osteoblasts protect AML cells from SDF-1-induced apoptosis. J Cell Biochem (2014) 0.82

MHC class II epitope nesting modulates dendritic cell function and improves generation of antigen-specific CD4 helper T cells. J Immunol (2011) 0.81

Measuring the proximity of T-lymphocyte CXCR4 and TCR by fluorescence resonance energy transfer (FRET). Methods Enzymol (2009) 0.80