Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
B-cell depletion with rituximab in relapsing-remitting multiple sclerosis.
|
N Engl J Med
|
2008
|
12.90
|
2
|
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
|
N Engl J Med
|
2012
|
7.58
|
3
|
Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial.
|
Lancet
|
2011
|
3.76
|
4
|
Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis.
|
J Immunol
|
2007
|
2.68
|
5
|
Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein.
|
Nat Med
|
2007
|
2.64
|
6
|
Chronic cerebrospinal venous insufficiency and multiple sclerosis.
|
Ann Neurol
|
2010
|
2.63
|
7
|
Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis.
|
Arch Neurol
|
2006
|
2.62
|
8
|
The therapeutic potential of mesenchymal stem cell transplantation as a treatment for multiple sclerosis: consensus report of the International MSCT Study Group.
|
Mult Scler
|
2010
|
2.45
|
9
|
B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6-producing B cells.
|
J Exp Med
|
2012
|
2.36
|
10
|
MRI parameters for prediction of multiple sclerosis diagnosis in children with acute CNS demyelination: a prospective national cohort study.
|
Lancet Neurol
|
2011
|
2.12
|
11
|
Natalizumab effects on immune cell responses in multiple sclerosis.
|
Ann Neurol
|
2006
|
2.06
|
12
|
Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study.
|
Lancet Neurol
|
2011
|
1.92
|
13
|
Distinct profiles of human B cell effector cytokines: a role in immune regulation?
|
J Immunol
|
2004
|
1.89
|
14
|
Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study.
|
Lancet Neurol
|
2007
|
1.88
|
15
|
Maraviroc and JC virus-associated immune reconstitution inflammatory syndrome.
|
N Engl J Med
|
2014
|
1.75
|
16
|
Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions.
|
Lancet Neurol
|
2007
|
1.73
|
17
|
Comparison of polarization properties of human adult microglia and blood-derived macrophages.
|
Glia
|
2012
|
1.73
|
18
|
Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease.
|
J Clin Invest
|
2003
|
1.59
|
19
|
NeuriteTracer: a novel ImageJ plugin for automated quantification of neurite outgrowth.
|
J Neurosci Methods
|
2007
|
1.59
|
20
|
Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment.
|
J Immunol
|
2008
|
1.58
|
21
|
Long-term follow-up of a phase 2 study of oral teriflunomide in relapsing multiple sclerosis: safety and efficacy results up to 8.5 years.
|
Mult Scler
|
2012
|
1.55
|
22
|
Distinct properties of circulating CD8+ T cells in FTY720-treated patients with multiple sclerosis.
|
Arch Neurol
|
2010
|
1.51
|
23
|
Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis.
|
J Immunol
|
2009
|
1.50
|
24
|
TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function.
|
J Immunol
|
2011
|
1.47
|
25
|
B cells in multiple sclerosis: connecting the dots.
|
Curr Opin Immunol
|
2011
|
1.45
|
26
|
Risk genes associated with pediatric-onset MS but not with monophasic acquired CNS demyelination.
|
Neurology
|
2013
|
1.44
|
27
|
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS.
|
J Neurosci
|
2005
|
1.43
|
28
|
Initiation of plasminogen activation on the surface of monocytes expressing the type II transmembrane serine protease matriptase.
|
Blood
|
2006
|
1.36
|
29
|
Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.
|
J Immunol
|
2004
|
1.34
|
30
|
Quantitative analysis of human endogenous retrovirus-W env in neuroinflammatory diseases.
|
AIDS Res Hum Retroviruses
|
2006
|
1.34
|
31
|
Microglia and multiple sclerosis.
|
J Neurosci Res
|
2005
|
1.34
|
32
|
Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis.
|
Ann Neurol
|
2012
|
1.32
|
33
|
Distinction and temporal stability of conformational epitopes on myelin oligodendrocyte glycoprotein recognized by patients with different inflammatory central nervous system diseases.
|
J Immunol
|
2013
|
1.27
|
34
|
Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation.
|
Ann Neurol
|
2013
|
1.27
|
35
|
2010 McDonald criteria for diagnosing pediatric multiple sclerosis.
|
Ann Neurol
|
2012
|
1.21
|
36
|
miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization.
|
Ann Neurol
|
2013
|
1.21
|
37
|
Neuromyelitis optica with hypothalamic involvement.
|
Mult Scler
|
2005
|
1.20
|
38
|
Determinants of human B cell migration across brain endothelial cells.
|
J Immunol
|
2003
|
1.19
|
39
|
Lesion distribution in children with clinically isolated syndromes.
|
Ann Neurol
|
2008
|
1.17
|
40
|
Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions.
|
J Neuroimmunol
|
2003
|
1.16
|
41
|
B-cell-derived interleukin-10 in autoimmune disease: regulating the regulators.
|
Nat Rev Immunol
|
2008
|
1.14
|
42
|
Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA.
|
Arch Neurol
|
2009
|
1.10
|
43
|
Treatment of multiple sclerosis with anti-CD20 antibodies.
|
Clin Immunol
|
2011
|
1.10
|
44
|
Do myelin-directed antibodies predict multiple sclerosis?
|
N Engl J Med
|
2003
|
1.10
|
45
|
Additive effect of the combination of glatiramer acetate and minocycline in a model of MS.
|
J Neuroimmunol
|
2005
|
1.09
|
46
|
Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis.
|
Ann Neurol
|
2010
|
1.08
|
47
|
Roles of immunoglobulins and B cells in multiple sclerosis: from pathogenesis to treatment.
|
J Neuroimmunol
|
2006
|
1.06
|
48
|
Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes.
|
Ann Neurol
|
2008
|
1.05
|
49
|
Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia.
|
Glia
|
2007
|
1.03
|
50
|
Elevated serum inflammatory markers in post-poliomyelitis syndrome.
|
J Neurol Sci
|
2008
|
1.03
|
51
|
Cholecalciferol plus calcium suppresses abnormal PBMC reactivity in patients with multiple sclerosis.
|
J Clin Endocrinol Metab
|
2011
|
1.02
|
52
|
Cost-effectiveness of interferon beta-1a, interferon beta-1b, and glatiramer acetate in newly diagnosed non-primary progressive multiple sclerosis.
|
Value Health
|
2004
|
1.02
|
53
|
Transient increases in anti-aquaporin-4 antibody titers following rituximab treatment in neuromyelitis optica, in association with elevated serum BAFF levels.
|
J Clin Neurosci
|
2011
|
1.02
|
54
|
Patient and community preferences for treatments and health states in multiple sclerosis.
|
Mult Scler
|
2003
|
1.01
|
55
|
From bench to MS bedside: challenges translating biomarker discovery to clinical practice.
|
J Neuroimmunol
|
2012
|
0.99
|
56
|
Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity.
|
Brain
|
2005
|
0.98
|
57
|
The relationship between risk attitude and treatment choice in patients with relapsing-remitting multiple sclerosis.
|
Med Decis Making
|
2002
|
0.98
|
58
|
Effects of delayed-release dimethyl fumarate on MRI measures in the Phase 3 DEFINE study.
|
J Neurol
|
2014
|
0.97
|
59
|
Differential responses of human microglia and blood-derived myeloid cells to FTY720.
|
J Neuroimmunol
|
2010
|
0.97
|
60
|
Quality of life outcomes with BG-12 (dimethyl fumarate) in patients with relapsing-remitting multiple sclerosis: the DEFINE study.
|
Mult Scler
|
2013
|
0.96
|
61
|
Myelin regulates immune cell adhesion and motility.
|
Exp Neurol
|
2009
|
0.96
|
62
|
Regulation of miRNA 219 and miRNA Clusters 338 and 17-92 in Oligodendrocytes.
|
Front Genet
|
2012
|
0.94
|
63
|
Reduction of the peripheral blood CD56(bright) NK lymphocyte subset in FTY720-treated multiple sclerosis patients.
|
J Immunol
|
2011
|
0.94
|
64
|
Therapies for multiple sclerosis: considerations in the pediatric patient.
|
Nat Rev Neurol
|
2011
|
0.93
|
65
|
Reconstitution of circulating lymphocyte counts in FTY720-treated MS patients.
|
Clin Immunol
|
2010
|
0.92
|
66
|
MicroRNA dysregulation in multiple sclerosis.
|
Front Genet
|
2013
|
0.92
|
67
|
Secretory products of multiple sclerosis B cells are cytotoxic to oligodendroglia in vitro.
|
J Neuroimmunol
|
2012
|
0.91
|
68
|
Dendritic cell differentiation signals induce anti-inflammatory properties in human adult microglia.
|
J Immunol
|
2008
|
0.90
|
69
|
International Pediatric MS Study Group Clinical Trials Summit: meeting report.
|
Neurology
|
2013
|
0.89
|
70
|
Harnessing the therapeutic potential of mesenchymal stem cells in multiple sclerosis.
|
Expert Rev Neurother
|
2011
|
0.87
|
71
|
Reduced thymic output and peripheral naïve CD4 T-cell alterations in primary progressive multiple sclerosis (PPMS).
|
J Neuroimmunol
|
2011
|
0.87
|
72
|
A condensed performance-validation strategy for multiplex detection kits used in studies of human clinical samples.
|
J Immunol Methods
|
2012
|
0.86
|
73
|
Lipid-specific immunoglobulin M bands in cerebrospinal fluid are associated with a reduced risk of developing progressive multifocal leukoencephalopathy during treatment with natalizumab.
|
Ann Neurol
|
2015
|
0.86
|
74
|
Epstein-Barr virus in oral shedding of children with multiple sclerosis.
|
Neurology
|
2013
|
0.85
|
75
|
Fatigue in post-poliomyelitis syndrome: association with disease-related, behavioral, and psychosocial factors.
|
PM R
|
2009
|
0.85
|
76
|
Dual effects of daily FTY720 on human astrocytes in vitro: relevance for neuroinflammation.
|
J Neuroinflammation
|
2013
|
0.85
|
77
|
Polysomnographic measures of disturbed sleep are associated with reduced quality of life in multiple sclerosis.
|
J Neurol Sci
|
2012
|
0.84
|
78
|
Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis.
|
Ann Neurol
|
2014
|
0.84
|
79
|
A proteome map of axoglial specializations isolated and purified from human central nervous system.
|
Glia
|
2010
|
0.84
|
80
|
Pharmacological treatment of early multiple sclerosis.
|
Drugs
|
2008
|
0.84
|
81
|
CTLA-4 dysregulation in the activation of myelin basic protein reactive T cells may distinguish patients with multiple sclerosis from healthy controls.
|
J Autoimmun
|
2003
|
0.83
|
82
|
What do we know about the mechanism of action of disease-modifying treatments in MS?
|
J Neurol
|
2004
|
0.83
|
83
|
Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS.
|
Neurology
|
2014
|
0.82
|
84
|
Masquerades of acquired demyelination in children: experiences of a national demyelinating disease program.
|
J Child Neurol
|
2012
|
0.82
|
85
|
Differential effects of Th1 and Th2 lymphocyte supernatants on human microglia.
|
Glia
|
2003
|
0.81
|
86
|
EBV and brain matter(s)?
|
Neurology
|
2010
|
0.81
|
87
|
Neurite outgrowth is differentially impacted by distinct immune cell subsets.
|
Mol Cell Neurosci
|
2011
|
0.80
|
88
|
Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosis.
|
Mult Scler
|
2013
|
0.80
|
89
|
Emerging multiple sclerosis disease-modifying therapies.
|
Curr Opin Neurol
|
2009
|
0.80
|
90
|
Magnetization transfer ratio in the delayed-release dimethyl fumarate DEFINE study.
|
J Neurol
|
2014
|
0.80
|
91
|
Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with multiple sclerosis.
|
Neurology
|
2013
|
0.79
|
92
|
A further TWEAK to multiple sclerosis pathophysiology.
|
Mol Neurobiol
|
2013
|
0.79
|
93
|
Dynamics of B-Cell Populations in CSF and Blood in Patients Treated with a Combination of Rituximab and Mitoxantrone.
|
ISRN Neurol
|
2013
|
0.79
|
94
|
Innate immune-mediated neuronal injury consequent to loss of astrocytes.
|
J Neuropathol Exp Neurol
|
2008
|
0.78
|
95
|
Laquinimod in multiple sclerosis.
|
Clin Immunol
|
2011
|
0.78
|
96
|
Inflammatory potential and migratory capacities across human brain endothelial cells of distinct glatiramer acetate-reactive T cells generated in treated multiple sclerosis patients.
|
Clin Immunol
|
2004
|
0.77
|
97
|
Beta interferons in clinically isolated syndromes: a meta-analysis.
|
Arq Neuropsiquiatr
|
2008
|
0.77
|
98
|
Defining multiple sclerosis treatment response with magnetic resonance imaging: how much activity is too much?
|
Arch Neurol
|
2009
|
0.77
|
99
|
Potential for interferon beta-induced serum antibodies in multiple sclerosis to inhibit endogenous interferon-regulated chemokine/cytokine responses within the central nervous system.
|
Arch Neurol
|
2006
|
0.77
|
100
|
Clinical and MRI activity as determinants of sample size for pediatric multiple sclerosis trials.
|
Neurology
|
2013
|
0.77
|
101
|
Myeloid lineage cells inhibit neurite outgrowth through a myosin II-dependent mechanism.
|
J Neuroimmunol
|
2011
|
0.77
|
102
|
MicroRNA Expression Patterns in Human Astrocytes in Relation to Anatomical Location and Age.
|
J Neuropathol Exp Neurol
|
2016
|
0.76
|
103
|
Antigen-specific therapies in multiple sclerosis.
|
Expert Opin Emerg Drugs
|
2009
|
0.76
|
104
|
Epidural blood patch in a patient with multiple sclerosis: is it safe?
|
Can J Anaesth
|
2013
|
0.75
|
105
|
Premature immune senescence in children with MS: Too young to go steady.
|
Neurology
|
2013
|
0.75
|
106
|
High CCR5 expression in natalizumab-associated progressive multifocal leukoencephalopathy immune reconstitution inflammatory syndrome supports treatment with the CCR5 inhibitor maraviroc.
|
Acta Neuropathol
|
2015
|
0.75
|
107
|
Cross-reactivity between epidemiology and immunology in multiple sclerosis.
|
Neurology
|
2008
|
0.75
|
108
|
8th international congress of neuroimmunology.
|
J Neuroimmunol
|
2007
|
0.75
|
109
|
B-cell subsets: cellular interactions and relevance in multiple sclerosis.
|
Expert Rev Clin Immunol
|
2007
|
0.75
|
110
|
Considering a career in neurology research? Heed these words.
|
Ann Neurol
|
2013
|
0.75
|