Published in PLoS One on January 15, 2014
CD5-mediated inhibition of TCR signaling proceeds normally in the absence of SHP-1. Int J Mol Med (2016) 0.75
Inherited functional variants of the lymphocyte receptor CD5 influence melanoma survival. Int J Cancer (2016) 0.75
Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol (1999) 8.98
A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. Immunity (2008) 6.73
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation. Immunity (2002) 4.60
Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3. Nat Med (2001) 4.50
Origins and functions of B-1 cells with notes on the role of CD5. Annu Rev Immunol (2001) 3.65
Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J Exp Med (1996) 3.36
A role for CD5 in TCR-mediated signal transduction and thymocyte selection. Science (1995) 2.84
Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. J Clin Invest (2006) 2.75
Antibodies to Tp67 and Tp44 augment and sustain proliferative responses of activated T cells. J Immunol (1985) 2.46
Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to its human counterpart Leu-1/T1 (CD5). Proc Natl Acad Sci U S A (1987) 2.13
Fine tuning of TCR signaling by CD5. J Immunol (2001) 2.02
Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1. Nature (1986) 1.98
The SRCR superfamily: a family reminiscent of the Ig superfamily. Trends Biochem Sci (1994) 1.93
CD5-mediated negative regulation of antigen receptor-induced growth signals in B-1 B cells. Science (1996) 1.84
Human CD5 promotes B-cell survival through stimulation of autocrine IL-10 production. Blood (2002) 1.69
The Scavenger Receptor Cysteine-Rich (SRCR) domain: an ancient and highly conserved protein module of the innate immune system. Crit Rev Immunol (2004) 1.59
Monoclonal antibodies to the CD5 antigen can provide the necessary second signal for activation of isolated resting T cells by solid-phase-bound OKT3. J Immunol (1986) 1.52
Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo. J Exp Med (1994) 1.31
The CD5 ectodomain interacts with conserved fungal cell wall components and protects from zymosan-induced septic shock-like syndrome. Proc Natl Acad Sci U S A (2009) 1.28
Relevance of CD6-mediated interactions in T cell activation and proliferation. J Immunol (2004) 1.27
The recirculating B cell pool contains two functionally distinct, long-lived, posttransitional, follicular B cell populations. J Immunol (2007) 1.27
Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding. Eur J Immunol (1997) 1.22
Regulation of immunity and autoimmunity by B cells. Curr Opin Immunol (2010) 1.21
CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn. Proc Natl Acad Sci U S A (1992) 1.20
The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis. Pharmacol Rev (2011) 1.19
The accessory molecules CD5 and CD6 associate on the membrane of lymphoid T cells. J Biol Chem (2002) 1.09
Suppression, subversion and escape: the role of regulatory T cells in cancer progression. Clin Exp Immunol (2013) 1.06
The immunomodulatory properties of the CD5 lymphocyte receptor in health and disease. Curr Opin Immunol (2011) 1.05
Cutting edge: critical role for CD5 in experimental autoimmune encephalomyelitis: inhibition of engagement reverses disease in mice. J Immunol (2004) 1.05
Intracellular events involved in CD5-induced human T cell activation and proliferation. J Immunol (1992) 1.03
CD5 plays an inhibitory role in the suppressive function of murine CD4(+) CD25(+) T(reg) cells. Immunol Lett (2008) 0.99
Characterization of a CD6 ligand(s) expressed on human- and murine-derived cell lines and murine lymphoid tissues. Cell Immunol (1994) 0.98
Increased numbers of thymic and peripheral CD4+ CD25+Foxp3+ cells in the absence of CD5 signaling. Eur J Immunol (2009) 0.96
CD5-mediated inhibition of TCR signaling during intrathymic selection and development does not require the CD5 extracellular domain. Eur J Immunol (2002) 0.95
CD5 signal transduction: positive or negative modulation of antigen receptor signaling. Crit Rev Immunol (2000) 0.93
CD5-dependent CK2 activation pathway regulates threshold for T cell anergy. J Immunol (2012) 0.92
Biochemical characterization of recombinant and circulating human Spalpha. Tissue Antigens (2004) 0.91
Defects in the regulation of B cell apoptosis are required for the production of citrullinated peptide autoantibodies in mice. Arthritis Rheum (2003) 0.86
Rescue of tumor-infiltrating lymphocytes from activation-induced cell death enhances the antitumor CTL response in CD5-deficient mice. J Immunol (2011) 0.86
High circulating levels of soluble scavenger receptors (sCD5 and sCD6) in patients with primary Sjögren's syndrome. Rheumatology (Oxford) (2001) 0.84
Identification of a natural soluble form of human CD5. Tissue Antigens (1999) 0.83
CD5 sweetens lymphocyte responses. Proc Natl Acad Sci U S A (2009) 0.81
Cell-free CD5 in patients with rheumatic diseases. Immunol Lett (1992) 0.78
Expression, purification and crystallization of human CD5 domain III, a nano-scale crystallization example. J Struct Biol (2007) 0.77
Intravenous immune globulin effects on serum-soluble CD5 levels in atopic dermatitis. Clin Exp Allergy (2001) 0.77
Exploiting scavenger receptors in cancer immunotherapy: Lessons from CD5 and SR-B1. Eur J Immunol (2017) 0.75