Published in Scientifica (Cairo) on December 26, 2013
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science (2006) 18.74
1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest (2002) 9.50
Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol (2004) 6.35
Mechanotransduction in vascular physiology and atherogenesis. Nat Rev Mol Cell Biol (2009) 4.58
1,25-dihydroxyvitamin D3 receptors in human leukocytes. Science (1983) 4.34
Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. J Chem Neuroanat (2005) 4.14
Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin. Cell Host Microbe (2009) 3.95
Nonclassic actions of vitamin D. J Clin Endocrinol Metab (2008) 3.71
Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation (2008) 3.69
Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation (2003) 3.55
Integration of the extranuclear and nuclear actions of estrogen. Mol Endocrinol (2005) 3.44
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A (2006) 3.38
Immunomodulatory effects of Vitamin D in multiple sclerosis. Brain (2009) 3.27
The ADVANCE study: a randomized study to evaluate the effects of cinacalcet plus low-dose vitamin D on vascular calcification in patients on hemodialysis. Nephrol Dial Transplant (2010) 3.10
Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J (2006) 2.99
25-hydroxyvitamin D levels inversely associate with risk for developing coronary artery calcification. J Am Soc Nephrol (2009) 2.87
Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels. Diabet Med (2008) 2.85
1,25-dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. J Biol Chem (2007) 2.61
Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. J Immunol (2009) 2.45
Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: a meta-analysis of prospective studies. Circ Cardiovasc Qual Outcomes (2012) 2.43
Immune effector mechanisms implicated in atherosclerosis: from mice to humans. Immunity (2013) 2.37
1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus. Circulation (2009) 2.36
25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension (2010) 2.33
Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction. Proc Natl Acad Sci U S A (2001) 2.30
Effect of vitamin D deficiency and replacement on endothelial function in asymptomatic subjects. J Clin Endocrinol Metab (2009) 2.28
The effect of different doses of vitamin D(3) on markers of vascular health in patients with type 2 diabetes: a randomised controlled trial. Diabetologia (2010) 2.26
Inflammation and atherosclerosis: novel insights into plaque formation and destabilization. Stroke (2006) 2.24
Fibroblast growth factor-23 and death, heart failure, and cardiovascular events in community-living individuals: CHS (Cardiovascular Health Study). J Am Coll Cardiol (2012) 2.22
The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells. J Cell Biochem (2003) 2.22
Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies. Am J Clin Nutr (2011) 2.16
Vitamin D: health panacea or false prophet? Nutrition (2012) 2.15
Effect of a single, oral, high-dose vitamin D supplementation on endothelial function in patients with peripheral arterial disease: a randomised controlled pilot study. Eur J Vasc Endovasc Surg (2012) 2.12
On the Vitamin D. Biochem J (1922) 2.12
Unusual CD4+CD28null T lymphocytes and recurrence of acute coronary events. J Am Coll Cardiol (2007) 2.09
Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus. Ann Rheum Dis (2011) 2.06
Molecular mechanisms of vitamin D action. Calcif Tissue Int (2012) 2.06
Serum 25-hydroxyvitamin D3 concentrations and carotid artery intima-media thickness among type 2 diabetic patients. Clin Endocrinol (Oxf) (2006) 2.05
25-hydroxyvitamin D, biomarkers of endothelial dysfunction and subclinical organ damage in adults with hypertension. Am J Hypertens (2013) 2.05
Hypercalcemia in an anephric patient with sarcoidosis: evidence for extrarenal generation of 1,25-dihydroxyvitamin D. N Engl J Med (1981) 2.00
Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health Initiative. Menopause (2010) 2.00
Dendritic cells: immune regulators in health and disease. Physiol Rev (2002) 1.99
Serum 25-hydroxyvitamin d levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish. Calcif Tissue Int (2009) 1.96
Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis. Int J Cardiovasc Imaging (2010) 1.91
Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets. J Steroid Biochem Mol Biol (2004) 1.89
Oral administration of an active form of vitamin D3 (calcitriol) decreases atherosclerosis in mice by inducing regulatory T cells and immature dendritic cells with tolerogenic functions. Arterioscler Thromb Vasc Biol (2010) 1.87
Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract (2006) 1.84
The vitamin D receptor is present in caveolae-enriched plasma membranes and binds 1 alpha,25(OH)2-vitamin D3 in vivo and in vitro. Mol Endocrinol (2004) 1.80
IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway. J Immunol (2008) 1.79
Vitamin D status is associated with arterial stiffness and vascular dysfunction in healthy humans. J Am Coll Cardiol (2011) 1.72
Levels of vitamin D and cardiometabolic disorders: systematic review and meta-analysis. Maturitas (2009) 1.71
Arterial and cardiac disease in young adults with childhood-onset end-stage renal disease-impact of calcium and vitamin D therapy. Nephrol Dial Transplant (2006) 1.67
Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)₂vitamin D₃: genomic and non-genomic mechanisms. Best Pract Res Clin Endocrinol Metab (2011) 1.66
Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology (2012) 1.66
CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden. Arterioscler Thromb Vasc Biol (2007) 1.59
Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells. Biol Reprod (2006) 1.57
Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan study. Stroke (2011) 1.57
1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation. Blood (2005) 1.53
Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. Circulation (1996) 1.51
Hypovitaminosis D in chronic kidney disease. Clin J Am Soc Nephrol (2008) 1.50
Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells. Blood (2003) 1.47
25-Hydroxyvitamin D is lower in deprived groups, but is not associated with carotid intima media thickness or plaques: results from pSoBid. Atherosclerosis (2012) 1.46
Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J Steroid Biochem Mol Biol (2005) 1.45
Cytochromes P450 are essential players in the vitamin D signaling system. Biochim Biophys Acta (2010) 1.43
T-cell cytokines differentially control human monocyte antimicrobial responses by regulating vitamin D metabolism. Proc Natl Acad Sci U S A (2010) 1.42
Extrarenal expression of the 25-hydroxyvitamin D-1-hydroxylase. Arch Biochem Biophys (2012) 1.41
Randomized controlled trial of vitamin D supplement on endothelial function in patients with type 2 diabetes. Atherosclerosis (2012) 1.39
Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes. J Bone Miner Res (2005) 1.37
The role of vitamin D in cancer prevention and treatment. Endocrinol Metab Clin North Am (2010) 1.37
Low 25(OH)D3 levels are associated with total adiposity, metabolic syndrome, and hypertension in Caucasian children and adolescents. Eur J Endocrinol (2011) 1.35
Distinct infiltration of neutrophils in lesion shoulders in ApoE-/- mice. Am J Pathol (2010) 1.35
Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses. J Immunol (2012) 1.35
Evidence for extra-renal 1 alpha-hydroxylation of 25-hydroxyvitamin D3 in pregnancy. Science (1979) 1.34
Expression of the vitamin d receptor is increased in the hypertrophic heart. Hypertension (2008) 1.33
25-Hydroxyvitamin D and parathyroid hormone are not associated with carotid intima-media thickness or plaque in the multi-ethnic study of atherosclerosis. Arterioscler Thromb Vasc Biol (2013) 1.33
Cardiovascular disease risk factors: epidemiology and risk assessment. Am J Cardiol (2010) 1.33
Vitamin D and vascular calcification. Curr Opin Lipidol (2007) 1.32
Assessment of atherosclerosis: the role of flow-mediated dilatation. Eur Heart J (2010) 1.32
Vitamin D is linked to carotid intima-media thickness and immune reconstitution in HIV-positive individuals. Antivir Ther (2011) 1.28
Identification of a specific binding protein for 1 alpha,25-dihydroxyvitamin D3 in basal-lateral membranes of chick intestinal epithelium and relationship to transcaltachia. J Biol Chem (1994) 1.26
Vitamin D deficiency is associated with depletion of circulating endothelial progenitor cells and endothelial dysfunction in patients with type 2 diabetes. J Clin Endocrinol Metab (2011) 1.25
Conventional dendritic cells at the crossroads between immunity and cholesterol homeostasis in atherosclerosis. Circulation (2009) 1.23
Caveolin-1: role in cell signaling. Adv Exp Med Biol (2012) 1.21
Serum vitamin D, parathyroid hormone levels, and carotid atherosclerosis. Atherosclerosis (2009) 1.21
The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling. Sci Signal (2009) 1.21
1Alpha,25-dihydroxyvitamin D3 inhibits CD40L-induced pro-inflammatory and immunomodulatory activity in human monocytes. Cytokine (2009) 1.20
1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes. J Steroid Biochem Mol Biol (2008) 1.19
Serum 25-hydroxyvitamin D concentration in subclinical carotid atherosclerosis. Arterioscler Thromb Vasc Biol (2013) 1.18
Increased expression of 25-hydroxyvitamin D-1alpha-hydroxylase in dysgerminomas: a novel form of humoral hypercalcemia of malignancy. Am J Pathol (2004) 1.17
Factors involved in vascular calcification and atherosclerosis in maintenance haemodialysis patients. Nephrol Dial Transplant (2006) 1.17
Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4. J Cell Biochem (2005) 1.17
Dendritic cells in atherosclerotic disease. Clin Immunol (2009) 1.17
Prostatic 25-hydroxyvitamin D-1alpha-hydroxylase and its implication in prostate cancer. J Cell Biochem (2003) 1.12
Vitamin D levels and markers of arterial dysfunction in HIV. AIDS Res Hum Retroviruses (2011) 1.12
Vitamin D status and risk of cardiovascular events: lessons learned via systematic review and meta-analysis. Cardiol Rev (2011) 1.11
Suppressive effect of 1alpha,25-dihydroxyvitamin D3 on type I IFN-mediated monocyte differentiation into dendritic cells: impairment of functional activities and chemotaxis. J Immunol (2005) 1.11
Vitamin D deficiency and coronary artery calcification in subjects with type 1 diabetes. Diabetes Care (2010) 1.11
Positive and negative regulations of the renal 25-hydroxyvitamin D3 1alpha-hydroxylase gene by parathyroid hormone, calcitonin, and 1alpha,25(OH)2D3 in intact animals. Endocrinology (1999) 1.10
Vitamin D inadequacy is associated with significant coronary artery stenosis in a community-based elderly cohort: the Korean Longitudinal Study on Health and Aging. J Clin Endocrinol Metab (2011) 1.09
The effect of vitamin D replacement on markers of vascular health in stroke patients - a randomised controlled trial. Nutr Metab Cardiovasc Dis (2010) 1.07
CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo. Proc Natl Acad Sci U S A (2013) 1.07