| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
2
|
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
|
Nat Genet
|
2008
|
22.35
|
|
3
|
Common variants near MC4R are associated with fat mass, weight and risk of obesity.
|
Nat Genet
|
2008
|
15.94
|
|
4
|
Genome-wide association study identifies eight loci associated with blood pressure.
|
Nat Genet
|
2009
|
12.44
|
|
5
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
6
|
Combined effect of health behaviours and risk of first ever stroke in 20,040 men and women over 11 years' follow-up in Norfolk cohort of European Prospective Investigation of Cancer (EPIC Norfolk): prospective population study.
|
BMJ
|
2009
|
3.89
|
|
7
|
Polymorphisms associated with circulating sex hormone levels in postmenopausal women.
|
J Natl Cancer Inst
|
2004
|
3.53
|
|
8
|
Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.
|
Am J Clin Nutr
|
2009
|
2.74
|
|
9
|
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
|
Nat Genet
|
2011
|
2.73
|
|
10
|
Telomere length in prospective and retrospective cancer case-control studies.
|
Cancer Res
|
2010
|
2.30
|
|
11
|
Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
|
PLoS Med
|
2010
|
2.25
|
|
12
|
Subclinical hyperthyroidism and the risk of coronary heart disease and mortality.
|
Arch Intern Med
|
2012
|
2.24
|
|
13
|
A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.
|
Cancer Res
|
2003
|
2.21
|
|
14
|
Depression and ischemic heart disease mortality: evidence from the EPIC-Norfolk United Kingdom prospective cohort study.
|
Am J Psychiatry
|
2008
|
2.14
|
|
15
|
Plasma vitamin C concentrations predict risk of incident stroke over 10 y in 20 649 participants of the European Prospective Investigation into Cancer Norfolk prospective population study.
|
Am J Clin Nutr
|
2008
|
2.01
|
|
16
|
Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort.
|
Am J Clin Nutr
|
2010
|
1.79
|
|
17
|
Subclinical thyroid dysfunction and the risk of heart failure events: an individual participant data analysis from 6 prospective cohorts.
|
Circulation
|
2012
|
1.79
|
|
18
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
|
19
|
IGF1 and IGFBP3 tagging polymorphisms are associated with circulating levels of IGF1, IGFBP3 and risk of breast cancer.
|
Hum Mol Genet
|
2005
|
1.62
|
|
20
|
Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: the European prospective investigation of cancer (EPIC)-Norfolk cohort study.
|
Diabetes Care
|
2009
|
1.53
|
|
21
|
Lifestyle factors and p53 mutation patterns in colorectal cancer patients in the EPIC-Norfolk study.
|
Mutagenesis
|
2010
|
1.46
|
|
22
|
Physical functional health predicts the incidence of coronary heart disease in the European Prospective Investigation into Cancer-Norfolk prospective population-based study.
|
Int J Epidemiol
|
2010
|
1.44
|
|
23
|
Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective investigation of cancer and nutrition-norfolk.
|
Cancer Epidemiol Biomarkers Prev
|
2004
|
1.41
|
|
24
|
Smoking status and differential white cell count in men and women in the EPIC-Norfolk population.
|
Atherosclerosis
|
2003
|
1.35
|
|
25
|
A prospective study of the association between quantity and variety of fruit and vegetable intake and incident type 2 diabetes.
|
Diabetes Care
|
2012
|
1.35
|
|
26
|
Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.
|
Cancer Epidemiol Biomarkers Prev
|
2012
|
1.26
|
|
27
|
Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary.
|
Diabetologia
|
2014
|
1.26
|
|
28
|
Life stress, emotional health, and mean telomere length in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.
|
J Gerontol A Biol Sci Med Sci
|
2011
|
1.24
|
|
29
|
Relation between self-reported physical functional health and chronic disease mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.
|
Ann Epidemiol
|
2005
|
1.24
|
|
30
|
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.
|
Breast Cancer Res
|
2007
|
1.22
|
|
31
|
Prevalence of refractive error in Europe: the European Eye Epidemiology (E(3)) Consortium.
|
Eur J Epidemiol
|
2015
|
1.18
|
|
32
|
Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women.
|
Cancer Epidemiol Biomarkers Prev
|
2006
|
1.18
|
|
33
|
STK15 polymorphisms and association with risk of invasive ovarian cancer.
|
Cancer Epidemiol Biomarkers Prev
|
2004
|
1.18
|
|
34
|
Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors.
|
BMC Cancer
|
2011
|
1.15
|
|
35
|
Energy intake at breakfast and weight change: prospective study of 6,764 middle-aged men and women.
|
Am J Epidemiol
|
2007
|
1.13
|
|
36
|
Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database.
|
Am J Clin Nutr
|
2009
|
1.11
|
|
37
|
Accuracy of death certification and hospital record linkage for identification of incident stroke.
|
BMC Med Res Methodol
|
2008
|
1.11
|
|
38
|
Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship?
|
Stroke
|
2007
|
1.09
|
|
39
|
Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): a population-based cross-sectional study.
|
Public Health Nutr
|
2007
|
1.09
|
|
40
|
Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study.
|
BMC Cancer
|
2010
|
1.09
|
|
41
|
Combined work and leisure physical activity and risk of stroke in men and women in the European prospective investigation into Cancer-Norfolk Prospective Population Study.
|
Neuroepidemiology
|
2006
|
1.08
|
|
42
|
Measured height loss predicts fractures in middle-aged and older men and women: the EPIC-Norfolk prospective population study.
|
J Bone Miner Res
|
2008
|
1.06
|
|
43
|
Seventeen year risk of all-cause and cause-specific mortality associated with C-reactive protein, fibrinogen and leukocyte count in men and women: the EPIC-Norfolk study.
|
Eur J Epidemiol
|
2013
|
1.06
|
|
44
|
Socioeconomic position and risk of short-term weight gain: prospective study of 14,619 middle-aged men and women.
|
BMC Public Health
|
2008
|
1.05
|
|
45
|
Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: the EPIC-Norfolk prospective population study.
|
Arterioscler Thromb Vasc Biol
|
2012
|
1.04
|
|
46
|
Mammographic breast density and breast cancer: evidence of a shared genetic basis.
|
Cancer Res
|
2012
|
1.03
|
|
47
|
N-Nitroso compounds and cancer incidence: the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study.
|
Am J Clin Nutr
|
2011
|
1.02
|
|
48
|
Healthy lifestyle choices: could sense of coherence aid health promotion?
|
J Epidemiol Community Health
|
2007
|
1.02
|
|
49
|
A new tool for converting food frequency questionnaire data into nutrient and food group values: FETA research methods and availability.
|
BMJ Open
|
2014
|
1.01
|
|
50
|
Implications of gene-environment interaction in studies of gene variants in breast cancer: an example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene.
|
Cancer Res
|
2006
|
1.01
|
|
51
|
Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.
|
Cancer Epidemiol Biomarkers Prev
|
2008
|
1.01
|
|
52
|
Bone mineral density and incidence of stroke: European prospective investigation into cancer-norfolk population-based study, systematic review, and meta-analysis.
|
Stroke
|
2014
|
1.00
|
|
53
|
Mendelian Randomisation Study of Childhood BMI and Early Menarche.
|
J Obes
|
2011
|
0.99
|
|
54
|
Modifiable lifestyle behaviors and functional health in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.
|
Prev Med
|
2006
|
0.98
|
|
55
|
Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.
|
Public Health Nutr
|
2006
|
0.98
|
|
56
|
Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk.
|
Nutr Cancer
|
2006
|
0.98
|
|
57
|
Associations of endogenous testosterone and SHBG with glycated haemoglobin in middle-aged and older men.
|
Clin Endocrinol (Oxf)
|
2011
|
0.97
|
|
58
|
Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions.
|
Cancer Epidemiol Biomarkers Prev
|
2005
|
0.96
|
|
59
|
Body fat percentage, body mass index and waist-to-hip ratio as predictors of mortality and cardiovascular disease.
|
Heart
|
2014
|
0.96
|
|
60
|
Incidence of type 2 diabetes using proposed HbA1c diagnostic criteria in the european prospective investigation of cancer-norfolk cohort: implications for preventive strategies.
|
Diabetes Care
|
2010
|
0.96
|
|
61
|
Cigarette smoking and endogenous sex hormones in postmenopausal women.
|
J Clin Endocrinol Metab
|
2011
|
0.95
|
|
62
|
Is QUS or DXA better for predicting the 10-year absolute risk of fracture?
|
J Bone Miner Res
|
2009
|
0.94
|
|
63
|
Lifestyle behaviours and quality-adjusted life years in middle and older age.
|
Age Ageing
|
2011
|
0.93
|
|
64
|
Using lifestyle factors to identify individuals at higher risk of inflammatory polyarthritis (results from the European Prospective Investigation of Cancer-Norfolk and the Norfolk Arthritis Register--the EPIC-2-NOAR Study).
|
Ann Rheum Dis
|
2013
|
0.92
|
|
65
|
Self-reported mental health-related quality of life and mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.
|
Psychosom Med
|
2007
|
0.91
|
|
66
|
Educational attainment and mean leukocyte telomere length in women in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.
|
Brain Behav Immun
|
2011
|
0.91
|
|
67
|
Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study.
|
Eur Heart J
|
2007
|
0.91
|
|
68
|
Longitudinal association of C-reactive protein and lung function over 13 years: The EPIC-Norfolk study.
|
Am J Epidemiol
|
2013
|
0.90
|
|
69
|
SMAD7 and MGMT genotype variants and cancer incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk Study.
|
Cancer Epidemiol
|
2010
|
0.89
|
|
70
|
MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.
|
DNA Repair (Amst)
|
2010
|
0.89
|
|
71
|
Identification of a novel percent mammographic density locus at 12q24.
|
Hum Mol Genet
|
2012
|
0.88
|
|
72
|
Distribution and determinants of C-reactive protein in the older adult population: European Prospective Investigation into Cancer-Norfolk study.
|
Eur J Clin Invest
|
2013
|
0.87
|
|
73
|
Physical activity reduces the risk of symptomatic gallstones: a prospective cohort study.
|
Eur J Gastroenterol Hepatol
|
2010
|
0.87
|
|
74
|
Baseline alcohol consumption, type of alcoholic beverage and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition-Norfolk study.
|
Cancer Epidemiol
|
2009
|
0.86
|
|
75
|
The association between physical activity in different domains of life and risk of osteoporotic fractures.
|
Bone
|
2010
|
0.85
|
|
76
|
A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.
|
PLoS One
|
2012
|
0.85
|
|
77
|
No evidence that social stress is associated with breast cancer incidence.
|
Breast Cancer Res Treat
|
2009
|
0.85
|
|
78
|
Smoking predicts long-term mortality in stroke: The European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.
|
Prev Med
|
2006
|
0.84
|
|
79
|
Effect of age on the relationship of occupational social class with prevalence of modifiable cardiovascular risk factors and cardiovascular diseases. A population-based cross-sectional study from European Prospective Investigation into Cancer - Norfolk (EPIC-Norfolk).
|
Gerontology
|
2006
|
0.83
|
|
80
|
Association between plasma vitamin C concentrations and blood pressure in the European prospective investigation into cancer-Norfolk population-based study.
|
Hypertension
|
2011
|
0.83
|
|
81
|
Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men.
|
J Nutr
|
2005
|
0.83
|
|
82
|
Major depression, C-reactive protein, and incident ischemic heart disease in healthy men and women.
|
Psychosom Med
|
2008
|
0.83
|
|
83
|
The aetiology of symptomatic gallstones quantification of the effects of obesity, alcohol and serum lipids on risk. Epidemiological and biomarker data from a UK prospective cohort study (EPIC-Norfolk).
|
Eur J Gastroenterol Hepatol
|
2011
|
0.83
|
|
84
|
C-reactive protein and fracture risk: European prospective investigation into Cancer Norfolk Study.
|
Bone
|
2013
|
0.82
|
|
85
|
Association between dietary phyto-oestrogens and bone density in men and postmenopausal women.
|
Br J Nutr
|
2011
|
0.81
|
|
86
|
Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.
|
BMC Cancer
|
2005
|
0.81
|
|
87
|
Fibrinogen and cigarette smoking in men and women in the European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) population.
|
Eur J Cardiovasc Prev Rehabil
|
2005
|
0.81
|
|
88
|
Differences in dietary supplement use and secular and seasonal trends assessed using three different instruments in the EPIC-Norfolk population study.
|
J Diet Suppl
|
2013
|
0.81
|
|
89
|
Testosterone, SHBG and differential white blood cell count in middle-aged and older men.
|
Maturitas
|
2012
|
0.81
|
|
90
|
Estimation of absolute fracture risk among middle-aged and older men and women: the EPIC-Norfolk population cohort study.
|
Eur J Epidemiol
|
2009
|
0.80
|
|
91
|
Respiratory function as a marker of bone health and fracture risk in an older population.
|
J Bone Miner Res
|
2009
|
0.80
|
|
92
|
Risk factors for first-ever stroke in the EPIC-Norfolk prospective population-based study.
|
Eur J Cardiovasc Prev Rehabil
|
2008
|
0.80
|
|
93
|
Obesity indices and self-reported functional health in men and women in the EPIC-Norfolk.
|
Obesity (Silver Spring)
|
2006
|
0.79
|
|
94
|
Physical activity and fibrinogen concentrations in 23,201 men and women in the EPIC-Norfolk population-based study.
|
Atherosclerosis
|
2007
|
0.79
|
|
95
|
Effect of age and sex on the relationship between different socioeconomic indices and self-reported functional health in the EPIC-Norfolk population-based study.
|
Ann Epidemiol
|
2009
|
0.78
|
|
96
|
The effect of including quantitative heel ultrasound in models for estimation of 10-year absolute risk of fracture.
|
Bone
|
2009
|
0.78
|
|
97
|
Investigating Physical Activity in the Etiology of Pancreatic Cancer: The Age at Which This Is Measured Is Important and Is Independent of Body Mass Index.
|
Pancreas
|
2016
|
0.77
|
|
98
|
No association between APOE and major depressive disorder in a community sample of 17,507 adults.
|
J Psychiatr Res
|
2009
|
0.77
|
|
99
|
CHD risk in relation to alcohol intake from categorical and open-ended dietary instruments.
|
Public Health Nutr
|
2010
|
0.76
|
|
100
|
Demographic and disease-related predictors of abnormal lung function in patients with established inflammatory polyarthritis and a comparison with the general population.
|
Ann Rheum Dis
|
2012
|
0.75
|
|
101
|
Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study.
|
Eur J Heart Fail
|
2013
|
0.75
|
|
102
|
Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.
|
Thromb Haemost
|
2016
|
0.75
|
|
103
|
Social adversity experience and blood pressure control following antihypertensive medication use in a community sample of older adults.
|
Int J Behav Med
|
2014
|
0.75
|
|
104
|
Estimated dietary intakes and sources of flavanols in the German population (German National Nutrition Survey II).
|
Eur J Nutr
|
2013
|
0.75
|
|
105
|
The Short-Form Six-Dimension utility index predicted mortality in the European Prospective Investigation into Cancer-Norfolk prospective population-based study.
|
J Clin Epidemiol
|
2009
|
0.75
|