Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR4.

PubWeight™: 0.91‹?›

🔗 View Article (PMID 24549946)

Published in Mol Nutr Food Res on December 23, 2013

Authors

Fermín Capitán-Cañadas1, Mercedes Ortega-González, Emilia Guadix, Antonio Zarzuelo, María Dolores Suárez, Fermín Sánchez de Medina, Olga Martínez-Augustin

Author Affiliations

1: Department of Biochemistry and Molecular Biology II, CIBERehd, School of Pharmacy, University of Granada, Granada, Spain.

Articles citing this

Sex differences in gut fermentation and immune parameters in rats fed an oligofructose-supplemented diet. Biol Sex Differ (2015) 0.85

Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells. Microorganisms (2016) 0.81

In Vitro Evidence for Immune-Modulatory Properties of Non-Digestible Oligosaccharides: Direct Effect on Human Monocyte Derived Dendritic Cells. PLoS One (2015) 0.81

Post-sensitization administration of non-digestible oligosaccharides and Bifidobacterium breve M-16V reduces allergic symptoms in mice. Immun Inflamm Dis (2016) 0.79

Intrinsic immunomodulatory effects of low-digestible carbohydrates selectively extend their anti-inflammatory prebiotic potentials. Biomed Res Int (2015) 0.77

Pectin- Derived Acidic Oligosaccharides Improve the Outcome of Pseudomonas aeruginosa Lung Infection in C57BL/6 Mice. PLoS One (2015) 0.77

An In Vitro Approach to Study Effects of Prebiotics and Probiotics on the Faecal Microbiota and Selected Immune Parameters Relevant to the Elderly. PLoS One (2016) 0.75

Effects of orally administered galacto-oligosaccharides on immunological parameters in foals: a pilot study. BMC Vet Res (2014) 0.75

Fructans As DAMPs or MAMPs: Evolutionary Prospects, Cross-Tolerance, and Multistress Resistance Potential. Front Plant Sci (2017) 0.75

Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function. Sci Rep (2017) 0.75

An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. PLoS One (2016) 0.75

Pathogen-induced secretory diarrhea and its prevention. Eur J Clin Microbiol Infect Dis (2016) 0.75

Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota. Microbiome (2017) 0.75

Fructooligosaccharides exert intestinal anti-inflammatory activity in the CD4+ CD62L+ T cell transfer model of colitis in C57BL/6J mice. Eur J Nutr (2015) 0.75

Articles by these authors

Reversible Ponceau staining as a loading control alternative to actin in Western blots. Anal Biochem (2010) 2.63

Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Biochem Pharmacol (2008) 2.04

In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway. Eur J Immunol (2005) 1.97

Effects of dietary fibers on disturbances clustered in the metabolic syndrome. J Nutr Biochem (2007) 1.89

Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats. Obesity (Silver Spring) (2008) 1.80

Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. J Hypertens (2006) 1.79

Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats. J Hypertens (2002) 1.57

Effects of dietary fiber on inflammatory bowel disease. Mol Nutr Food Res (2005) 1.51

Evaluation of the preventative effects exerted by Lactobacillus fermentum in an experimental model of septic shock induced in mice. Br J Nutr (2008) 1.42

The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype. J Cancer Res Clin Oncol (2006) 1.36

Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship. Biochem Pharmacol (2006) 1.34

Molecular bases of impaired water and ion movements in inflammatory bowel diseases. Inflamm Bowel Dis (2009) 1.20

Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis. J Nutr (2005) 1.18

Short-chain fructooligosaccharides, in spite of being fermented in the upper part of the large intestine, have anti-inflammatory activity in the TNBS model of colitis. Eur J Nutr (2006) 1.14

Anti-inflammatory effect of diosmectite in hapten-induced colitis in the rat. Br J Pharmacol (2004) 1.13

Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis. World J Gastroenterol (2005) 1.12

Quercetin inhibits vascular superoxide production induced by endothelin-1: Role of NADPH oxidase, uncoupled eNOS and PKC. Atherosclerosis (2008) 1.08

The intestinal anti-inflammatory effect of quercitrin is associated with an inhibition in iNOS expression. Br J Pharmacol (2004) 1.07

Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats. J Nutr (2002) 1.01

Lactobacillus fermentum, a probiotic capable to release glutathione, prevents colonic inflammation in the TNBS model of rat colitis. Int J Colorectal Dis (2005) 0.99

Medicine-related problems resulting in emergency department visits. Eur J Clin Pharmacol (2006) 0.98

A comparative study of the preventative effects exerted by two probiotics, Lactobacillus reuteri and Lactobacillus fermentum, in the trinitrobenzenesulfonic acid model of rat colitis. Br J Nutr (2007) 0.98

Goat milk oligosaccharides are anti-inflammatory in rats with hapten-induced colitis. J Nutr (2006) 0.98

Wine polyphenols improve endothelial function in large vessels of female spontaneously hypertensive rats. Hypertension (2008) 0.96

Intestinal inflammation and mucosal barrier function. Inflamm Bowel Dis (2014) 0.94

Preventative effects of lactulose in the trinitrobenzenesulphonic acid model of rat colitis. Inflamm Bowel Dis (2005) 0.94

Active hexose correlated compound acts as a prebiotic and is antiinflammatory in rats with hapten-induced colitis. J Nutr (2007) 0.94

Induction of alkaline phosphatase in the inflamed intestine: a novel pharmacological target for inflammatory bowel disease. Biochem Pharmacol (2004) 0.93

The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice. Biochem Pharmacol (2011) 0.93

Chronic administration of genistein improves endothelial dysfunction in spontaneously hypertensive rats: involvement of eNOS, caveolin and calmodulin expression and NADPH oxidase activity. Clin Sci (Lond) (2007) 0.92

Polyphenols restore endothelial function in DOCA-salt hypertension: role of endothelin-1 and NADPH oxidase. Free Radic Biol Med (2007) 0.92

Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis. Immunobiology (2010) 0.92

Intestinal anti-inflammatory activity of paepalantine, an isocoumarin isolated from the capitula of Paepalanthus bromelioides, in the trinitrobenzenesulphonic acid model of rat colitis. Planta Med (2004) 0.92

Antihypertensive effects of peroxisome proliferator-activated receptor-β activation in spontaneously hypertensive rats. Hypertension (2011) 0.91

A diet supplemented with husks of Plantago ovata reduces the development of endothelial dysfunction, hypertension, and obesity by affecting adiponectin and TNF-alpha in obese Zucker rats. J Nutr (2005) 0.90

Endothelium-dependent vasodilator effects of peroxisome proliferator-activated receptor beta agonists via the phosphatidyl-inositol-3 kinase-Akt pathway. J Pharmacol Exp Ther (2009) 0.90

Effects of chronic quercetin treatment in experimental renovascular hypertension. Mol Cell Biochem (2005) 0.90

The intestinal antiinflammatory agent glycomacropeptide has immunomodulatory actions on rat splenocytes. Biochem Pharmacol (2010) 0.90

Nondigestible oligosaccharides exert nonprebiotic effects on intestinal epithelial cells enhancing the immune response via activation of TLR4-NFκB. Mol Nutr Food Res (2013) 0.89

Tissue-nonspecific alkaline phosphatase is activated in enterocytes by oxidative stress via changes in glycosylation. Inflamm Bowel Dis (2011) 0.89

Bovine glycomacropeptide has intestinal antiinflammatory effects in rats with dextran sulfate-induced colitis. J Nutr (2010) 0.89

Bovine glycomacropeptide is anti-inflammatory in rats with hapten-induced colitis. J Nutr (2005) 0.88

The intestinal anti-inflammatory activity of UR-12746S on reactivated experimental colitis is mediated through downregulation of cytokine production. Inflamm Bowel Dis (2003) 0.88

Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis. BMC Genomics (2008) 0.88

Effects of chronic quercetin treatment on antioxidant defence system and oxidative status of deoxycorticosterone acetate-salt-hypertensive rats. Mol Cell Biochem (2004) 0.88

Disturbances in epithelial ionic secretion in different experimental models of colitis. Life Sci (2004) 0.86

The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties. Pharmacol Res (2010) 0.85

The combination of fructooligosaccharides and resistant starch shows prebiotic additive effects in rats. Clin Nutr (2010) 0.85

Intestinal anti-inflammatory activity of hydroalcoholic extracts of Phlomis purpurea L. and Phlomis lychnitis L. in the trinitrobenzenesulphonic acid model of rat colitis. J Ethnopharmacol (2013) 0.84

A shorter and more specific oral sensitization-based experimental model of food allergy in mice. J Immunol Methods (2012) 0.84

Plantago ovata husks-supplemented diet ameliorates metabolic alterations in obese Zucker rats through activation of AMP-activated protein kinase. Comparative study with other dietary fibers. Clin Nutr (2009) 0.83

Lack of beneficial metabolic effects of quercetin in adult spontaneously hypertensive rats. Eur J Pharmacol (2009) 0.83

Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis. Int Immunopharmacol (2012) 0.83

Effects of chronic chrysin treatment in spontaneously hypertensive rats. Planta Med (2002) 0.83

Soy isoflavones improve endothelial function in spontaneously hypertensive rats in an estrogen-independent manner: role of nitric-oxide synthase, superoxide, and cyclooxygenase metabolites. J Pharmacol Exp Ther (2005) 0.83

UR-1505, a new salicylate, blocks T cell activation through nuclear factor of activated T cells. Mol Pharmacol (2007) 0.82

Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways. Br J Pharmacol (2009) 0.82

Effect of flavonoids on rat splenocytes, a structure-activity relationship study. Biochem Pharmacol (2008) 0.82

Intestinal anti-inflammatory effects of oligosaccharides derived from lactulose in the trinitrobenzenesulfonic acid model of rat colitis. J Agric Food Chem (2014) 0.81

Effects of quercetin treatment on vascular function in deoxycorticosterone acetate-salt hypertensive rats. Comparative study with verapamil. Planta Med (2004) 0.81

Endothelial nitric oxide production stimulated by the bioflavonoid chrysin in rat isolated aorta. Planta Med (2005) 0.81

New insights into the immunological effects of food bioactive peptides in animal models of intestinal inflammation. Proc Nutr Soc (2010) 0.81

A Porphyra columbina hydrolysate upregulates IL-10 production in rat macrophages and lymphocytes through an NF-κB, and p38 and JNK dependent mechanism. Food Chem (2012) 0.80