Hypoxia promotes the proliferation of cervical carcinoma cells through stimulating the secretion of IL-8.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 3925901)

Published in Int J Clin Exp Pathol on January 15, 2014

Authors

Li-Bing Liu1, Feng Xie2, Kai-Kai Chang2, Ming-Qing Li2, Yu-Han Meng2, Xiao-Hui Wang2, Hui Li2, Da-Jin Li2, Jin-Jin Yu3

Author Affiliations

1: Department of Obstetrics and Gynecology, The Fourth Affiliated Hospital of Soochow University WuXi 214062, Jiangsu Province, China ; Laboratory for Reproductive Immunology, Hospital & Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College Shanghai 200011, China.
2: Laboratory for Reproductive Immunology, Hospital & Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College Shanghai 200011, China.
3: Department of Obstetrics and Gynecology, The Fourth Affiliated Hospital of Soochow University WuXi 214062, Jiangsu Province, China.

Articles cited by this

Targeting HIF-1 for cancer therapy. Nat Rev Cancer (2003) 28.01

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res (1999) 10.65

Breast and cervical cancer in 187 countries between 1980 and 2010: a systematic analysis. Lancet (2011) 7.71

Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell (2010) 7.20

The interleukin-8 pathway in cancer. Clin Cancer Res (2008) 7.12

Worldwide burden of cervical cancer in 2008. Ann Oncol (2011) 5.66

Neutrophil chemotactic factor produced by lipopolysaccharide (LPS)-stimulated human blood mononuclear leukocytes: partial characterization and separation from interleukin 1 (IL 1). J Immunol (1987) 5.64

Structure and functional expression of a human interleukin-8 receptor. Science (1991) 4.74

Levels of hypoxia-inducible factor-1 alpha during breast carcinogenesis. J Natl Cancer Inst (2001) 4.27

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature (2011) 4.07

Expression of interleukin-8 by human melanoma cells up-regulates MMP-2 activity and increases tumor growth and metastasis. Am J Pathol (1997) 2.15

Role of C-X-C chemokines as regulators of angiogenesis in lung cancer. J Leukoc Biol (1995) 1.64

Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis. Cancer Detect Prev (2004) 1.60

ERβ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells. Cancer Biol Ther (2011) 1.45

Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer. Gynecol Oncol (2006) 1.41

Eosinophilic granulocytes and damage-associated molecular pattern molecules (DAMPs): role in the inflammatory response within tumors. J Immunother (2007) 1.39

Clinical implications of expression of interleukin 8 related to angiogenesis in uterine cervical cancers. Cancer Res (2000) 1.31

Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer. Clin Cancer Res (2003) 1.30

Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. Am J Pathol (2003) 1.29

Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice. Br J Cancer (1999) 1.26

Roles for hypoxia-regulated genes during cervical carcinogenesis: somatic evolution during the hypoxia-glycolysis-acidosis sequence. Gynecol Oncol (2007) 1.13

Structure and functional expression of a human interleukin-8 receptor. Science. 1991. 253: 1278-1280. J Immunol (2009) 1.13

Effects of hypoxia and HIFs on cancer metabolism. Int J Hematol (2012) 1.13

Microenvironmental control of gene expression: implications for tumor angiogenesis, progression, and metastasis. Semin Radiat Oncol (1998) 1.09

Interleukin-8 concentration in peritoneal fluid of patients with endometriosis and modulation of interleukin-8 expression in human mesothelial cells. Mol Hum Reprod (1996) 1.09

Regulation of interleukin-8 gene expression in human endometrial cells in culture. Mol Cell Endocrinol (1993) 1.03

Hypoxia and angiogenesis in endometrioid endometrial carcinogenesis. Cell Oncol (2007) 1.00

CXCL8 enhances proliferation and growth and reduces apoptosis in endometrial stromal cells in an autocrine manner via a CXCR1-triggered PTEN/AKT signal pathway. Hum Reprod (2012) 1.00

Interleukin-8 is associated with adhesion, migration and invasion in human gastric cancer SCG-7901 cells. Med Oncol (2010) 0.98

Targeted blockade of interleukin-8 abrogates its promotion of cervical cancer growth and metastasis. Mol Cell Biochem (2012) 0.91

Cervical carcinoma cells stimulate the angiogenesis through TSLP promoting growth and activation of vascular endothelial cells. Am J Reprod Immunol (2013) 0.88