Published in Biochem Pharmacol on June 15, 1988
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A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats. Kidney Int (1992) 1.19
A point mutation in an invariant splice donor site leads to exon skipping in two unrelated Dutch patients with dihydropyrimidine dehydrogenase deficiency. J Inherit Metab Dis (1996) 1.16
Presence of N-unsubstituted glucosamine units in native heparan sulfate revealed by a monoclonal antibody. J Biol Chem (1995) 1.15
Expression of agrin, dystroglycan, and utrophin in normal renal tissue and in experimental glomerulopathies. Am J Pathol (2000) 1.12
Increased expression of heparanase in overt diabetic nephropathy. Kidney Int (2006) 1.11
Distribution of GBM heparan sulfate proteoglycan core protein and side chains in human glomerular diseases. Kidney Int (1993) 1.07
6-Mercaptopurine: cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts. Biochem Pharmacol (1993) 1.03
Elevated urine, blood and cerebrospinal fluid levels of uracil and thymine in a child with dihydrothymine dehydrogenase deficiency. Clin Chim Acta (1984) 1.03
Differential expression of agrin in renal basement membranes as revealed by domain-specific antibodies. J Biol Chem (1998) 1.02
Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity. Eur J Cancer (1997) 1.01
Purine enzymes in patients with rheumatoid arthritis treated with methotrexate. Ann Rheum Dis (2002) 0.94
Localization of the ICF syndrome to chromosome 20 by homozygosity mapping. Am J Hum Genet (1998) 0.94
Purine de novo synthesis as the basis of synergism of methotrexate and 6-mercaptopurine in human malignant lymphoblasts of different lineages. Biochem Pharmacol (1988) 0.92
Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection. J Clin Invest (1995) 0.92
Reduction in glomerular heparan sulfate correlates with complement deposition and albuminuria in active Heymann nephritis. J Am Soc Nephrol (1999) 0.89
Reversal of 6-mercaptopurine and 6-methylmercaptopurine ribonucleoside cytotoxicity by amidoimidazole carboxamide ribonucleoside in Molt F4 human malignant T-lymphoblasts. Biochem Pharmacol (1993) 0.89
Argininosuccinic aciduria: clinical and biochemical findings in three children with the late onset form, with special emphasis on cerebrospinal fluid findings of amino acids and pyrimidines. Neuropediatrics (1993) 0.88
Sequence-, time- and dose-dependent synergism of methotrexate and 6-mercaptopurine in malignant human T-lymphoblasts. Biochem Pharmacol (1986) 0.88
Reduction of heparan sulphate-associated anionic sites in the glomerular basement membrane of rats with streptozotocin-induced diabetic nephropathy. Diabetologia (1995) 0.88
Decrease in S-adenosylmethionine synthesis by 6-mercaptopurine and methylmercaptopurine ribonucleoside in Molt F4 human malignant lymphoblasts. Biochem J (1994) 0.87
Reversal of methylmercaptopurine ribonucleoside cytotoxicity by purine ribonucleosides and adenine. Biochem Pharmacol (1995) 0.87
Reference values for amino acids in cerebrospinal fluid of children determined using ion-exchange chromatography with fluorimetric detection. Clin Chim Acta (1989) 0.86
Polyamines and DNA methylation in childhood leukaemia. Biochem Soc Trans (2007) 0.86
Phytohaemagglutinin stimulation of peripheral lymphocytes in children with acute lymphoblastic leukaemia during remission. Scand J Haematol (1972) 0.86
2,8-Dihydroxyadenine stone formation in a renal transplant recipient due to adenine phosphoribosyltransferase deficiency. J Urol (1996) 0.86
2,8-Dihydroxyadenine urolithiasis in a patient with considerable residual adenine phosphoribosyltransferase activity in cell extracts but with mutations in both copies of APRT. Mol Genet Metab (2001) 0.85
Selective proteinuria in diabetic nephropathy in the rat is associated with a relative decrease in glomerular basement membrane heparan sulphate. Diabetologia (1995) 0.85
Megaloblastic anaemia in the Lesch-Nyhan syndrome. Lancet (1968) 0.85
Dihydropyrimidinase deficiency, a progressive neurological disorder? Neuropediatrics (1997) 0.84
Dose-related effects of methotrexate on purine and pyrimidine nucleotides and on cell-kinetic parameters in MOLT-4 malignant human T-lymphoblasts. Biochem Pharmacol (1986) 0.84
Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA)-resistant cells. Cancer Lett (1998) 0.83
Azathioprine-related bone marrow toxicity and low activities of purine enzymes in patients with rheumatoid arthritis. Arthritis Rheum (1995) 0.83
5-nucleotidase and azathioprine-related bone-marrow toxicity. Lancet (1993) 0.83
Genetic polymorphism of thiopurine S-methyltransferase in Argentina. Ann Clin Biochem (2003) 0.83
Sideroblastic anaemia. A review of seven paediatric cases. Eur J Pediatr (1982) 0.83
Dihydropyrimidine dehydrogenase deficiency. Neurological aspects. J Neurol Sci (1987) 0.82
Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene. Leukemia (2001) 0.82
The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts. Biochim Biophys Acta (1993) 0.82
Antiproteinuric effect of ciclosporin A in adriamycin nephropathy in rats. Nephron (1997) 0.81
The influence of adenine on the clinical features and purine metabolism in the Lesch-Nyhan syndrome. Acta Paediatr Scand (1970) 0.81
Purine enzymes in rheumatoid arthritis: possible association with response to azathioprine. A pilot study. Ann Rheum Dis (1994) 0.81
Disturbances of cerebral purine and pyrimidine metabolism in young children with chronic renal failure. Nephron (1991) 0.81
Citrullinaemia with rapidly fatal neonatal course. Arch Dis Child (1971) 0.81
Increase of HLA-"DRw6" in patients with juvenile chronic arthritis. Tissue Antigens (1983) 0.80
Production and characterization of a monoclonal antibody against human glomerular heparan sulfate. Lab Invest (1991) 0.80
Increased availability of phosphoribosyl pyrophosphate as the basis for enhanced 6-mercaptopurine incorporation by methotrexate, in cultured human lymphoblasts. Adv Exp Med Biol (1986) 0.79
Purine enzymes in rheumatoid arthritis. A clue to the prediction of the response to azathioprine? Review and hypothesis. Clin Exp Rheumatol (1995) 0.79
Elastase, but not proteinase 3 (PR3), induces proteinuria associated with loss of glomerular basement membrane heparan sulphate after in vivo renal perfusion in rats. Clin Exp Immunol (1996) 0.79
Determination of extracellular and intracellular thiopurines and methylthiopurines by high-performance liquid chromatography. J Chromatogr B Biomed Appl (1995) 0.79
Monoclonal antibodies against the protein core and glycosaminoglycan side chain of glomerular basement membrane heparan sulfate proteoglycan: characterization and immunohistological application in human tissues. J Histochem Cytochem (1994) 0.79
Identification of a four-base deletion (delTCAT296-299) in the dihydropyrimidine dehydrogenase gene with variable clinical expression. Hum Genet (1997) 0.79
Purine enzyme activities in peripheral blood mononuclear cells: comparison of a new non-radiochemical high-performance liquid chromatography procedure and a radiochemical thin-layer chromatography procedure. J Chromatogr B Biomed Appl (1995) 0.79
Concentration of purine nucleotides in erythrocytes of patients with the Lesch-Nyhan syndrome before and during oral administration of adenine. Acta Paediatr Scand (1971) 0.78
Biochemical evidence for synergistic combination treatment with methotrexate and 6-mercaptopurine in acute lymphoblastic leukemia. Haematol Blood Transfus (1990) 0.78
A patient with a deficiency of serum-carnosinase activity. Acta Paediatr Scand (1969) 0.78
Detection and identification of 6-methylmercapto-8-hydoxypurine, a major metabolite of 6-mercaptopurine, in plasma during intravenous administration. Clin Chem (1996) 0.78
Severe 5-fluorouracil toxicity caused by reduced dihydropyrimidine dehydrogenase activity due to heterozygosity for a G-->A point mutation. J Inherit Metab Dis (1998) 0.78
Purine enzyme activities in recent onset rheumatoid arthritis: are there differences between patients and healthy controls? Ann Rheum Dis (1996) 0.78
DNA methylation patterns in the calcitonin gene region at first diagnosis and at relapse of acute lymphoblastic leukemia (ALL). Leukemia (1997) 0.78
A biochemical basis for synergism of 6-mercaptopurine and mycophenolic acid in Molt F4, a human malignant T-lymphoblastic cell line. Biochim Biophys Acta (1993) 0.78
Reduced purine 5'-nucleotidase activity in lymphocytes of patients with systemic lupus erythematosus: results of a pilot study. Ann Rheum Dis (1999) 0.78
Pyrimidine metabolism in erythrocytes of the newborn. Biol Neonate (1979) 0.78
Inhibition of DNA methylation in malignant MOLT F4 lymphoblasts by 6-mercaptopurine. Clin Chem (1998) 0.78
Decrease of heparan sulfate staining in the glomerular basement membrane in murine lupus nephritis. Am J Pathol (1995) 0.78
The IMP dehydrogenase inhibitor mycophenolic acid antagonizes the CTP synthetase inhibitor 3-deazauridine in MOLT-3 human leukemia cells: a central role for phosphoribosyl pyrophosphate. Biochem Pharmacol (1995) 0.77
Cell surface adenosine deaminase (ADA) and its complexing protein (ADCP) in human T-lymphoid cells. Adv Exp Med Biol (1986) 0.77
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay. Clin Chim Acta (1978) 0.77
Concentration of nucleotides and deoxynucleotides in peripheral and phytohemagglutinin-stimulated mammalian lymphocytes. Effects of adenosine and deoxyadenosine. Biochim Biophys Acta (1983) 0.77
High-performance liquid chromatographic assay for identification and quantitation of nucleotides in lymphocytes and malignant lymphoblasts. J Chromatogr (1982) 0.77
Inhibition of IMP dehydrogenase by mycophenolic acid in Molt F4 human malignant lymphoblasts. Ann Clin Biochem (1994) 0.76
Morphology and incidence of the "posttherapeutic lymphoid cell" in the bone marrow of children with acute lymphoblastic leukemia. Am J Pathol (1986) 0.76
High-performance liquid chromatographic determination of purine and pyrimidine bases, ribonucleosides, deoxyribonucleosides and cyclic ribonucleotides in biological fluids. J Chromatogr (1982) 0.76
Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity. Adv Exp Med Biol (1998) 0.76
Mechanism of allopurinol-mediated inhibition and stabilization of human orotate phosphoribosyltransferase and orotidine phosphate decarboxylase. Biochem Pharmacol (1976) 0.76
Vessel wall heparan sulfate and transcapillary passage of albumin in experimental diabetes in the rat. Nephrol Dial Transplant (1997) 0.76