Published in Hum Mol Genet on February 20, 2014
The retinoblastoma protein and cell cycle control. Cell (1995) 20.21
Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science (1995) 7.25
Polymyositis and dermatomyositis. Lancet (2003) 7.24
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature (1999) 5.53
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev (1997) 5.22
Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell (1993) 4.90
Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis. J Cell Biol (1996) 3.71
Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle (2008) 3.37
MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation. Mol Cell Biol (1995) 3.32
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc Natl Acad Sci U S A (1994) 3.03
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci (2005) 2.94
119th ENMC international workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10-12 October 2003, Naarden, The Netherlands. Neuromuscul Disord (2004) 2.85
p21(WAF1/Cip1): more than a break to the cell cycle? Biochim Biophys Acta (2000) 2.81
Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? Nat Rev Neurosci (2007) 2.75
Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment. Trends Cell Biol (2005) 2.74
Inclusion body myositis and myopathies. Ann Neurol (1995) 2.68
Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev (1997) 2.65
DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci (2001) 2.60
Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr Opin Cell Biol (1994) 2.44
Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. Brain (2008) 2.18
Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. J Neurosci (2003) 2.14
P21 and p27: roles in carcinogenesis and drug resistance. Expert Rev Mol Med (2008) 2.10
Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science (1996) 2.03
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J Neurosci (1997) 2.00
Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron (2004) 1.99
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell (2002) 1.90
Chaperones in cell cycle regulation and mitogenic signal transduction: a review. Cell Prolif (2000) 1.90
Inclusion-body myositis: a myodegenerative conformational disorder associated with Abeta, protein misfolding, and proteasome inhibition. Neurology (2006) 1.87
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocr Rev (1999) 1.78
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.78
Divide and die: cell cycle events as triggers of nerve cell death. J Neurosci (2004) 1.74
Inflammation induces tau pathology in inclusion body myositis model via glycogen synthase kinase-3beta. Ann Neurol (2008) 1.71
Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models. J Neurosci (2006) 1.60
Cell-cycle targeted therapies. Lancet Oncol (2004) 1.55
Aneuploidy and DNA replication in the normal human brain and Alzheimer's disease. J Neurosci (2007) 1.52
The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid. Mol Biol Cell (2009) 1.45
Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies. Arthritis Rheum (1997) 1.45
Cyclin-dependent kinases as a therapeutic target for stroke. Proc Natl Acad Sci U S A (2000) 1.45
p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells. J Cell Biol (2000) 1.44
Cell division in the CNS: protective response or lethal event in post-mitotic neurons? Biochim Biophys Acta (2006) 1.41
Cyclins: roles in mitogenic signaling and oncogenic transformation. Growth Factors (2006) 1.40
Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism. J Neurosci (2005) 1.40
Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation (2008) 1.34
The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax. J Biol Chem (2001) 1.33
Assessment of satellite cell number and activity status in human skeletal muscle biopsies. Muscle Nerve (2009) 1.31
The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons. J Neurosci (2003) 1.30
Inflammatory muscle diseases: a critical review on pathogenesis and therapies. Curr Opin Pharmacol (2010) 1.30
Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty. J Clin Invest (1995) 1.29
CDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progression. Cell (2012) 1.29
Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest. Cancer Res (2000) 1.26
Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multi-protein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation. Brain Pathol (2009) 1.25
Comparison of the muscle fiber diameter and satellite cell frequency in human muscle biopsies. Muscle Nerve (1999) 1.24
Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathol (2003) 1.24
Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease. J Neurosci (2008) 1.23
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease. J Clin Invest (2009) 1.23
Induction of adiponectin in skeletal muscle by inflammatory cytokines: in vivo and in vitro studies. Endocrinology (2004) 1.22
Neuronal cell cycle re-entry mediates Alzheimer disease-type changes. Biochim Biophys Acta (2006) 1.19
Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species. Antioxid Redox Signal (2005) 1.19
Pax7 distribution in human skeletal muscle biopsies and myogenic tissue cultures. Cell Tissue Res (2003) 1.19
Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats. Neuroscience (2004) 1.18
Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat. J Cereb Blood Flow Metab (2002) 1.17
Bim is elevated in Alzheimer's disease neurons and is required for beta-amyloid-induced neuronal apoptosis. J Neurosci (2007) 1.14
Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. J Neurosci (2007) 1.14
Role of cytokines and chemokines in idiopathic inflammatory myopathies. Curr Opin Rheumatol (2009) 1.14
Targeting CDC37: an alternative, kinase-directed strategy for disruption of oncogenic chaperoning. Cell Cycle (2009) 1.13
Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents. Curr Pharm Des (2005) 1.11
Critical requirement for cell cycle inhibitors in sustaining nonproliferative states. J Cell Biol (2007) 1.11
New multiple labelling method for improved satellite cell identification in human muscle: application to a cohort of power-lifters and sedentary men. Histochem Cell Biol (2009) 1.08
Characterization of hereditary inclusion body myopathy myoblasts: possible primary impairment of apoptotic events. Cell Death Differ (2007) 1.05
Role of cell cycle re-entry in neurons: a common apoptotic mechanism of neuronal cell death. Neurotox Res (2011) 1.01
Why do neurons enter the cell cycle? Cell Cycle (2004) 0.99
MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling. Aging Cell (2012) 0.99
Ubiquitin-mediated proteolysis of vertebrate G1- and S-phase regulators. J Cell Physiol (2001) 0.98
A new murine model to define the critical pathologic and therapeutic mediators of polymyositis. Arthritis Rheum (2007) 0.96
Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase. Mol Cell Biol (2003) 0.96
Tumor necrosis factor-alpha expression in muscles of polymyositis and dermatomyositis. Acta Neuropathol (2000) 0.95
Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle. Neurobiol Aging (2008) 0.94
Beta-amyloid peptide expression is sufficient for myotube death: implications for human inclusion body myopathy. Mol Cell Neurosci (2001) 0.93
FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells. Int J Oncol (2004) 0.88
Inhibition of retinoblastoma protein phosphorylation by myogenesis-induced changes in the subunit composition of the cyclin-dependent kinase 4 complex. Cell Growth Differ (1996) 0.88
Definitive engagement of cytotoxic CD8 T cells in C protein-induced myositis, a murine model of polymyositis. Arthritis Rheum (2010) 0.85
Increased aging in primary muscle cultures of sporadic inclusion-body myositis. Neurobiol Aging (2008) 0.84
Endothelial and myogenic differentiation of hematopoietic progenitor cells in inflammatory myopathies. J Neuropathol Exp Neurol (2008) 0.84
Flavopiridol inhibits smooth muscle cell proliferation in vitro and neointimal formation In vivo after carotid injury in the rat. Circulation (1999) 0.84
Mitochondrial dysfunction in skeletal muscle of amyloid precursor protein-overexpressing mice. J Biol Chem (2012) 0.84
Triptolide inhibits rat vascular smooth muscle cell proliferation and cell cycle progression via attenuation of ERK1/2 and Rb phosphorylation. Exp Mol Pathol (2010) 0.84
Role of inducible heat shock protein 70 in radiation-induced cell death. Cell Stress Chaperones (2001) 0.83
Abeta treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. Eur J Neurosci (2007) 0.83
Myofibrillar myopathy. III. Abnormal expression of cyclin-dependent kinases and nuclear proteins. J Neuropathol Exp Neurol (1997) 0.82
Calpain inhibition attenuates intracellular changes in muscle cells in response to extracellular inflammatory stimulation. Exp Neurol (2010) 0.81
A novel approach to induce cell cycle reentry in terminally differentiated muscle cells. FASEB J (2001) 0.81
Intracellular β-amyloid accumulation leads to age-dependent progression of Ca2+ dysregulation in skeletal muscle. Muscle Nerve (2010) 0.81
Expression of myogenic regulatory factors and myo-endothelial remodeling in sporadic inclusion body myositis. Neuromuscul Disord (2012) 0.80
Advanced glycation end-product-induced mitogenesis is dependent on Janus kinase 2-induced heat shock protein 70 in normal rat kidney interstitial fibroblast cells. Transl Res (2007) 0.79
Foxo/atrogin induction in human and experimental myositis. Neurobiol Dis (2012) 0.79
The molecular chaperones in cell cycle control. Ann N Y Acad Sci (1998) 0.78
T-cell anti-apoptotic mechanisms in inflammatory myopathies. J Neuroimmunol (2000) 0.77
A novel WISp39 protein links Hsp90 and p21 stability to the G2/M checkpoint. Cancer Biol Ther (2005) 0.75
Oleate prevents palmitate-induced mitochondrial dysfunction, insulin resistance and inflammatory signaling in neuronal cells. Biochim Biophys Acta (2014) 0.86
Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin. Biochimie (2015) 0.77
Raf-kinase inhibitor GW5074 shows antibacterial activity against methicillin-resistant Staphylococcus aureus and potentiates the activity of gentamicin. Future Med Chem (2016) 0.77
Synergistic effects of β-amyloid and ceramide-induced insulin resistance on mitochondrial metabolism in neuronal cells. Biochim Biophys Acta (2015) 0.76