Is irritable bowel syndrome an organic disorder?

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Published in World J Gastroenterol on January 14, 2014

Authors

Magdy El-Salhy1, Doris Gundersen1, Odd Helge Gilja1, Jan Gunnar Hatlebakk1, Trygve Hausken1

Author Affiliations

1: Magdy El-Salhy, Section for Gastroenterology, Department of Medicine, Stord Helse-Fonna Hospital, 5409 Stord, Norway.

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Functional bowel disorders in apparently healthy people. Gastroenterology (1980) 8.52

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types. Am J Anat (1974) 8.05

U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci (1993) 7.98

Liver regeneration. Hepatology (2006) 7.52

Burden of gastrointestinal disease in the United States: 2012 update. Gastroenterology (2012) 7.15

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Ghrelin enhances appetite and increases food intake in humans. J Clin Endocrinol Metab (2001) 6.41

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Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther (1999) 2.28

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