Helicobacter pylori gamma-glutamyl transpeptidase and its pathogenic role.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMC 3921472)

Published in World J Gastroenterol on January 21, 2014

Authors

Vittorio Ricci1, Maria Giannouli1, Marco Romano1, Raffaele Zarrilli1

Author Affiliations

1: Vittorio Ricci, Department of Molecular Medicine, Human Physiology Section, University of Pavia Medical School, 27100 Pavia, Italy.

Articles citing this

Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis. World J Gastroenterol (2015) 0.87

What a Dinner Party! Mechanisms and Functions of Interkingdom Signaling in Host-Pathogen Associations. MBio (2016) 0.85

Genetic Adaptation of Achromobacter sp. during Persistence in the Lungs of Cystic Fibrosis Patients. PLoS One (2015) 0.84

Oral glutathione supplementation drastically reduces Helicobacter-induced gastric pathologies. Sci Rep (2016) 0.81

Use of larvae of the wax moth Galleria mellonella as an in vivo model to study the virulence of Helicobacter pylori. BMC Microbiol (2014) 0.78

Helicobacter, gamma-glutamyltransferase and cancer: further intriguing connections. World J Gastroenterol (2014) 0.78

Glutathione levels modulation as a strategy in host-parasite interactions-insights for biology of cancer. Front Pharmacol (2014) 0.78

Comparative Immune Response in Children and Adults with H. pylori Infection. J Immunol Res (2015) 0.78

Draft genome sequences of eight enterohepatic helicobacter species isolated from both laboratory and wild rodents. Genome Announc (2014) 0.78

Multiple Functions of Glutamate Uptake via Meningococcal GltT-GltM L-Glutamate ABC Transporter in Neisseria meningitidis Internalization into Human Brain Microvascular Endothelial Cells. Infect Immun (2015) 0.76

Immunization with Heat Shock Protein A and γ-Glutamyl Transpeptidase Induces Reduction on the Helicobacter pylori Colonization in Mice. PLoS One (2015) 0.75

γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis. Sci Rep (2016) 0.75

Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori. Gut Pathog (2017) 0.75

Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections. Front Cell Infect Microbiol (2017) 0.75

Articles cited by this

Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science (2003) 5.23

Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation. Science (2003) 3.00

Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol (2013) 2.16

Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin. Cell Host Microbe (2008) 1.96

Essential role of Helicobacter pylori gamma-glutamyltranspeptidase for the colonization of the gastric mucosa of mice. Mol Microbiol (1999) 1.91

Apoptosis in gastric epithelium induced by Helicobacter pylori infection: implications in gastric carcinogenesis. Am J Gastroenterol (2001) 1.85

Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells. Proc Natl Acad Sci U S A (2011) 1.81

Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion. Proc Natl Acad Sci U S A (2004) 1.77

gamma-Glutamyltranspeptidase from Escherichia coli K-12: purification and properties. J Bacteriol (1986) 1.71

Proteome analysis of secreted proteins of the gastric pathogen Helicobacter pylori. Infect Immun (2002) 1.70

Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase. Gastroenterology (2007) 1.49

Helicobacter pylori virulence factors: facts and fantasies. Curr Opin Gastroenterol (2005) 1.44

gamma-Glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonization. Infect Immun (2001) 1.44

Helicobacter pylori invades the gastric mucosa and translocates to the gastric lymph nodes. Lab Invest (2008) 1.41

Helicobacter pylori induces miR-155 in T cells in a cAMP-Foxp3-dependent manner. PLoS One (2010) 1.35

Helicobacter pylori gamma-glutamyl transpeptidase is a pathogenic factor in the development of peptic ulcer disease. Gastroenterology (2010) 1.31

Helicobacter pylori γ-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance. Proc Natl Acad Sci U S A (2013) 1.23

A novel apoptosis-inducing protein from Helicobacter pylori. Mol Microbiol (2003) 1.14

Metabolism of glutamine and glutathione via gamma-glutamyltranspeptidase and glutamate transport in Helicobacter pylori: possible significance in the pathophysiology of the organism. Mol Microbiol (2007) 1.13

Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets. J Immunol (2007) 1.09

Intoxication strategy of Helicobacter pylori VacA toxin. Trends Microbiol (2012) 1.08

Modulation of the CD4+ T-cell response by Helicobacter pylori depends on known virulence factors and bacterial cholesterol and cholesterol α-glucoside content. J Infect Dis (2011) 1.07

Helicobacter pylori gamma-glutamyltranspeptidase upregulates COX-2 and EGF-related peptide expression in human gastric cells. Cell Microbiol (2004) 1.06

Helicobacter pylori VacA induces programmed necrosis in gastric epithelial cells. Infect Immun (2011) 1.05

Uncoupling the enzymatic and autoprocessing activities of Helicobacter pylori gamma-glutamyltranspeptidase. J Biol Chem (2006) 1.04

Coupled amino acid deamidase-transport systems essential for Helicobacter pylori colonization. Infect Immun (2010) 1.02

Helicobacter pylori induces apoptosis of human monocytes but not monocyte-derived dendritic cells: role of the cag pathogenicity island. Infect Immun (2004) 0.97

Cutting edge: cyclooxygenase-2 activation suppresses Th1 polarization in response to Helicobacter pylori. J Immunol (2003) 0.96

Gamma-glutamyltranspeptidase of Helicobacter pylori induces mitochondria-mediated apoptosis in AGS cells. Biochem Biophys Res Commun (2007) 0.96

Characterization of Helicobacter pylori gamma-glutamyltranspeptidase reveals the molecular basis for substrate specificity and a critical role for the tyrosine 433-containing loop in catalysis. Biochemistry (2007) 0.96

Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori γ-glutamyl transpeptidase is mainly glutathione degradation-dependent. Cell Microbiol (2011) 0.95

Evidence for transepithelial dendritic cells in human H. pylori active gastritis. Helicobacter (2009) 0.94

A secreted low-molecular-weight protein from Helicobacter pylori induces cell-cycle arrest of T cells. Gastroenterology (2005) 0.92

Molecular cross-talk between Helicobacter pylori and human gastric mucosa. World J Gastroenterol (2011) 0.90

Relationship between Vac A toxin and ammonia in Helicobacter pylori-induced apoptosis in human gastric epithelial cells. J Physiol Pharmacol (2009) 0.88

Crystal structure of acivicin-inhibited gamma-glutamyltranspeptidase reveals critical roles for its C-terminus in autoprocessing and catalysis. Biochemistry (2009) 0.88

Mechanisms of disease: Helicobacter pylori-related gastric carcinogenesis--implications for chemoprevention. Nat Clin Pract Gastroenterol Hepatol (2006) 0.87

Helicobacter pylori-induced loss of survivin and gastric cell viability is attributable to secreted bacterial gamma-glutamyl transpeptidase activity. J Infect Dis (2013) 0.87

Evidence for conserved function of γ-glutamyltranspeptidase in Helicobacter genus. PLoS One (2012) 0.87

Helicobacter pylori gamma-glutamyltranspeptidase induces cell cycle arrest at the G1-S phase transition. J Microbiol (2010) 0.86

Effects of Helicobacter pylori γ-glutamyltranspeptidase on apoptosis and inflammation in human biliary cells. Dig Dis Sci (2012) 0.84

Significance of ammonia in the genesis of gastric epithelial lesions induced by Helicobacter pylori: an in vitro study with different bacterial strains and urea concentrations. Digestion (1996) 0.80