Possible molecular mechanisms linking air pollution and asthma in children.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMC 3941253)

Published in BMC Pulm Med on March 01, 2014

Authors

Susanna Esposito1, Rossana Tenconi, Mara Lelii, Valentina Preti, Erica Nazzari, Silvia Consolo, Maria Francesca Patria

Author Affiliations

1: Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Commenda 9, 20122 Milano, Italy. susanna.esposito@unimi.it.

Articles citing this

The effects of outdoor air pollution on the respiratory health of Canadian children: A systematic review of epidemiological studies. Can Respir J (2015) 0.86

Impact of air pollution on respiratory diseases in children with recurrent wheezing or asthma. BMC Pulm Med (2014) 0.84

Epigenetic regulation of the neural transcriptome and alcohol interference during development. Front Genet (2014) 0.82

Acute exposure to silica nanoparticles aggravate airway inflammation: different effects according to surface characteristics. Exp Mol Med (2015) 0.79

Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure. Environ Health Perspect (2016) 0.78

The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions. Environ Health Perspect (2016) 0.77

Factors Affecting Parent's Perception on Air Quality-From the Individual to the Community Level. Int J Environ Res Public Health (2016) 0.75

Effect of outdoor air pollution on asthma exacerbations in children and adults: Systematic review and multilevel meta-analysis. PLoS One (2017) 0.75

Bisphenol A exposure and asthma development in school-age children: a longitudinal study. PLoS One (2014) 0.75

Whole Blood Cytokine Response to Local Traffic-Related Particulate Matter in Peruvian Children With and Without Asthma. Front Pharmacol (2017) 0.75

Polycyclic aromatic hydrocarbons exposure, oxidative stress, and asthma in children. Int Arch Occup Environ Health (2017) 0.75

On the road to recovery: Gasoline content regulations and child health. J Health Econ (2017) 0.75

Abdominal adiposity intensifies the negative effects of ambient air pollution on lung function in Korean men. Int J Obes (Lond) (2017) 0.75

Articles cited by this

Health effects of fine particulate air pollution: lines that connect. J Air Waste Manag Assoc (2006) 17.73

The effect of air pollution on lung development from 10 to 18 years of age. N Engl J Med (2004) 8.58

Effect of exposure to traffic on lung development from 10 to 18 years of age: a cohort study. Lancet (2007) 5.34

Air pollution and development of asthma, allergy and infections in a birth cohort. Eur Respir J (2007) 3.42

Indoor air pollution from biomass combustion and acute respiratory infections in Kenya: an exposure-response study. Lancet (2001) 3.05

Endogenous ligands of TLR2 and TLR4: agonists or assistants? J Leukoc Biol (2010) 2.85

Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life. Am J Respir Crit Care Med (2009) 2.77

Genetic polymorphism of GSTM1 and antioxidant supplementation influence lung function in relation to ozone exposure in asthmatic children in Mexico City. Thorax (2004) 2.55

Relation of DNA methylation of 5'-CpG island of ACSL3 to transplacental exposure to airborne polycyclic aromatic hydrocarbons and childhood asthma. PLoS One (2009) 2.38

Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern. J Immunol (1997) 2.33

Traffic-related air pollution and childhood respiratory symptoms, function and allergies. Epidemiology (2008) 2.20

Recommendations for the design and analysis of epigenome-wide association studies. Nat Methods (2013) 2.19

Ambient air pollution impairs regulatory T-cell function in asthma. J Allergy Clin Immunol (2010) 2.12

Burden of disease attributable to selected environmental factors and injury among children and adolescents in Europe. Lancet (2004) 2.06

The role of air pollution in asthma and other pediatric morbidities. J Allergy Clin Immunol (2005) 2.02

Disruption of microRNA expression in human airway cells by diesel exhaust particles is linked to tumorigenesis-associated pathways. Environ Health Perspect (2009) 1.98

Children's response to air pollutants. J Toxicol Environ Health A (2008) 1.86

Acute effects of air pollution on pulmonary function, airway inflammation, and oxidative stress in asthmatic children. Environ Health Perspect (2008) 1.83

The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway disease. Allergy (1997) 1.83

Air pollution and child respiratory health: a case-crossover study in Australia and New Zealand. Am J Respir Crit Care Med (2005) 1.70

The glutathione-S-transferase Mu 1 null genotype modulates ozone-induced airway inflammation in human subjects. J Allergy Clin Immunol (2009) 1.57

Traffic related pollutants in Europe and their effect on allergic disease. Curr Opin Allergy Clin Immunol (2004) 1.55

Glutathione-S-transferase (GST) P1, GSTM1, exercise, ozone and asthma incidence in school children. Thorax (2008) 1.48

Histone acetylation regulates epithelial IL-8 release mediated by oxidative stress from environmental particles. Am J Physiol Lung Cell Mol Physiol (2002) 1.41

Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles. Am J Respir Cell Mol Biol (2002) 1.39

Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes. Environ Health Perspect (2010) 1.38

COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1. Am J Respir Cell Mol Biol (2007) 1.32

Influence of air pollution on respiratory health during perinatal development. Clin Exp Pharmacol Physiol (2006) 1.30

Diesel exhaust particles directly induce activated mast cells to degranulate and increase histamine levels and symptom severity. J Allergy Clin Immunol (2000) 1.26

Traffic-related air pollution and lung function in children at 8 years of age: a birth cohort study. Am J Respir Crit Care Med (2012) 1.25

Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma. Thorax (2010) 1.24

Synergism between rhinovirus infection and oxidant pollutant exposure enhances airway epithelial cell cytokine production. Environ Health Perspect (2002) 1.23

Ambient ozone primes pulmonary innate immunity in mice. J Immunol (2007) 1.21

Asthma and pregnancy: emerging evidence of epigenetic interactions in utero. Curr Opin Allergy Clin Immunol (2009) 1.21

Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children. J Allergy Clin Immunol (2011) 1.21

Role of hyaluronan and hyaluronan-binding proteins in human asthma. J Allergy Clin Immunol (2011) 1.19

Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc (2009) 1.19

Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia. J Appl Physiol (1985) (2007) 1.18

Exposure to air pollution from traffic and childhood asthma until 12 years of age. Epidemiology (2013) 1.15

The effect of ambient air pollution on exhaled nitric oxide in the Children's Health Study. Eur Respir J (2010) 1.14

Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis. Environ Health Perspect (2008) 1.13

Outdoor air pollution, genetic susceptibility, and asthma management: opportunities for intervention to reduce the burden of asthma. Pediatrics (2009) 1.11

Traffic-related air pollutants and exhaled markers of airway inflammation and oxidative stress in New York City adolescents. Environ Res (2012) 1.09

Air pollution particles diminish bacterial clearance in the primed lungs of mice. Toxicol Appl Pharmacol (2007) 1.08

Fine particles, a major threat to children. Int J Hyg Environ Health (2007) 1.08

Epigenetics, asthma, and allergic diseases: a review of the latest advancements. Curr Allergy Asthma Rep (2012) 1.07

The effect of environmental oxidative stress on airway inflammation. Curr Opin Allergy Clin Immunol (2012) 1.06

Long-term exposure to PM10 and NO2 in association with lung volume and airway resistance in the MAAS birth cohort. Environ Health Perspect (2013) 1.04

Early-life cockroach allergen and polycyclic aromatic hydrocarbon exposures predict cockroach sensitization among inner-city children. J Allergy Clin Immunol (2013) 1.04

Chronic effects of ambient air pollution on lung function among Chinese children. Arch Dis Child (2012) 1.03

PM10, and children's respiratory symptoms and lung function in the PATY study. Eur Respir J (2012) 1.03

Genomics and the respiratory effects of air pollution exposure. Respirology (2012) 1.03

TLR-2 is involved in airway epithelial cell response to air pollution particles. Toxicol Appl Pharmacol (2005) 1.03

Interactive effects of antioxidant genes and air pollution on respiratory function and airway disease: a HuGE review. Am J Epidemiol (2011) 1.00

Genetic variation in the glutathione synthesis pathway, air pollution, and children's lung function growth. Am J Respir Crit Care Med (2010) 0.97

Respiratory symptoms in children living near busy roads and their relationship to vehicular traffic: results of an Italian multicenter study (SIDRIA 2). Environ Health (2009) 0.93

Intrauterine exposure to fine particulate matter as a risk factor for increased susceptibility to acute broncho-pulmonary infections in early childhood. Int J Hyg Environ Health (2013) 0.91

Air pollution, genetics, and allergy: an update. Curr Opin Allergy Clin Immunol (2012) 0.91

Ten years of progress in the Hokkaido birth cohort study on environment and children's health: cohort profile--updated 2013. Environ Health Prev Med (2013) 0.90

Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Am J Epidemiol (2009) 0.90

T regulatory cells and allergy. Microbes Infect (2005) 0.89

Factors affecting the 27K DNA methylation pattern in asthmatic and healthy children from locations with various environments. Mutat Res (2013) 0.88

Adjuvant activity of particulate pollutants in different mouse models. Toxicology (2000) 0.88

Recent advances in the epigenetics and genomics of asthma. Curr Opin Allergy Clin Immunol (2011) 0.88

Advances in environmental and occupational disorders in 2012. J Allergy Clin Immunol (2013) 0.87

Interaction between respiratory syncytial virus and particulate matter in guinea pig alveolar macrophages. Am J Respir Cell Mol Biol (2003) 0.86

Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice. Toxicol Sci (2003) 0.86

An environmental epigenetic study of ADRB2 5'-UTR methylation and childhood asthma severity. Clin Exp Allergy (2012) 0.86

Residential proximity to a major roadway is associated with features of asthma control in children. PLoS One (2012) 0.85

Air pollution and children's respiratory health - gaps in the global evidence. Clin Exp Allergy (2011) 0.83

IL-22 mRNA expression in blood samples as a useful biomarker for assessing the adverse health effects of PCBs on allergic children. Int J Environ Res Public Health (2012) 0.81

The developmental origins of asthma: does epigenetics hold the key? Am J Respir Crit Care Med (2009) 0.78

Articles by these authors

Interdialytic weight gain in oligoanuric children and adolescents on chronic hemodialysis. Pediatr Nephrol (2014) 1.56

Live attenuated intranasal influenza vaccine. Hum Vaccin Immunother (2012) 1.51

Prevalence and Clinical Relevance of IgE Sensitization to Profilin in Childhood: A Multicenter Study. Int Arch Allergy Immunol (2015) 1.42

Clinical assessment of adenoidal obstruction based on the nasal obstruction index is no longer useful in children. Otolaryngol Head Neck Surg (2010) 1.42

Knowledge of human papillomavirus infection and its prevention among adolescents and parents in the greater Milan area, Northern Italy. BMC Public Health (2010) 1.03

Procalcitonin measurements for guiding antibiotic treatment in pediatric pneumonia. Respir Med (2011) 1.00

Pediatrician knowledge and attitudes regarding human papillomavirus disease and its prevention. Vaccine (2007) 0.98

Nasopharyngeal biofilm-producing otopathogens in children with nonsevere recurrent acute otitis media. Otolaryngol Head Neck Surg (2012) 0.97

Clinical profile of recurrent community-acquired pneumonia in children. BMC Pulm Med (2013) 0.91

Pollen-induced allergic rhinitis in 1360 Italian children: comorbidities and determinants of severity. Pediatr Allergy Immunol (2013) 0.87

Recurrences in chronic tonsillitis substained by tonsillar biofilm-producing bacteria in children. Relationship with the grade of tonsillar hyperplasy. Int J Pediatr Otorhinolaryngol (2012) 0.85

Impact of rhinoviruses on pediatric community-acquired pneumonia. Eur J Clin Microbiol Infect Dis (2011) 0.85

Efficacy of injectable trivalent virosomal-adjuvanted inactivated influenza vaccine in preventing acute otitis media in children with recurrent complicated or noncomplicated acute otitis media. Pediatr Infect Dis J (2009) 0.84

Impact of air pollution on respiratory diseases in children with recurrent wheezing or asthma. BMC Pulm Med (2014) 0.84

Medical prevention of recurrent acute otitis media: an updated overview. Expert Rev Anti Infect Ther (2014) 0.83

Association between radiological findings and severity of community-acquired pneumonia in children. Ital J Pediatr (2013) 0.83

Atopy in preschool Italian children with recurrent respiratory infections. Pediatr Med Chir (2009) 0.80

Nasal saline irrigation in preschool children: a survey of attitudes and prescribing habits of primary care pediatricians working in northern Italy. Ital J Pediatr (2014) 0.79

Peritoneal tuberculosis due to multidrug-resistant Mycobacterium tuberculosis. Pediatr Int (2013) 0.79

Pathophysiology, favoring factors, and associated disorders in otorhinosinusology. Pediatr Allergy Immunol (2012) 0.78

Genetic Polymorphisms of Functional Candidate Genes and Recurrent Acute Otitis Media With or Without Tympanic Membrane Perforation. Medicine (Baltimore) (2015) 0.77

Adenovirus 36 infection and obesity. J Clin Virol (2012) 0.77

Efficacy and safety of influenza vaccination in children with asthma. Expert Rev Vaccines (2012) 0.77

Correlates of exercise capacity in pediatric patients on chronic hemodialysis. J Ren Nutr (2013) 0.77

Reduction in catheter-related infections after switching from povidone-iodine to chlorhexidine for the exit-site care of tunneled central venous catheters in children on hemodialysis. Hemodial Int (2014) 0.76

Medical education and attitudes about acute otitis media guidelines: a survey of Italian pediatricians and otolaryngologists. Pediatr Infect Dis J (2009) 0.76

Knowledge of oxygen administration, aerosol medicine, and chest physiotherapy among pediatric healthcare workers in Italy. J Aerosol Med Pulm Drug Deliv (2011) 0.76

Immunogenicity, safety and tolerability of monovalent 2009 pandemic influenza A/H1N1 MF59-adjuvanted vaccine in children and adolescents with Williams or Cornelia De Lange syndrome. Hum Vaccin (2011) 0.76

Antibiotic treatment of acute otitis media in pediatrics. Future Microbiol (2011) 0.75

Health risks for children raised on vegan or vegetarian diets. Pediatr Crit Care Med (2006) 0.75

Chemotherapy against cancer during pregnancy: A systematic review on neonatal outcomes. Medicine (Baltimore) (2016) 0.75

Diagnosis of acute rhinosinusitis. Pediatr Allergy Immunol (2012) 0.75

Intestinal tuberculosis in a child living in a country with a low incidence of tuberculosis: a case report. BMC Res Notes (2014) 0.75

Treatment of Severe Hypervolemic Hyponatremia in a Child With Pneumonia. Pediatr Emerg Care (2016) 0.75

Intradialytic cycling in children and young adults on chronic hemodialysis. Pediatr Nephrol (2013) 0.75

Is there a link between infection due to adenovirus 36 and childhood obesity? Pediatr Infect Dis J (2012) 0.75