Published in Dev Biol on February 26, 2014
The cochlear sensory epithelium derives from Wnt responsive cells in the dorsomedial otic cup. Dev Biol (2015) 0.80
The role of foxi family transcription factors in the development of the ear and jaw. Curr Top Dev Biol (2015) 0.79
The mouse Foxi3 transcription factor is necessary for the development of posterior placodes. Dev Biol (2015) 0.76
Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse. PLoS One (2014) 0.75
Ephrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae. Dev Neurosci (2016) 0.75
Molecular architecture underlying fluid absorption by the developing inner ear. Elife (2017) 0.75
Beyond epithelial-to-mesenchymal transition: common suppression of differentiation programs underlies epithelial barrier dysfunction in mild, moderate and severe asthma. Allergy (2017) 0.75
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell (1998) 10.61
Notch signaling: the core pathway and its posttranslational regulation. Dev Cell (2009) 4.49
Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci U S A (2005) 4.25
Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron (1996) 4.12
Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafness. Nat Genet (1999) 3.73
Bidirectional modulation of synaptic functions by Eph/ephrin signaling. Nat Neurosci (2008) 2.85
Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development (1999) 2.48
Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development (1993) 2.39
Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome. Hum Mol Genet (2001) 2.34
EphB receptors coordinate migration and proliferation in the intestinal stem cell niche. Cell (2006) 2.22
Dlx5 regulates regional development of the branchial arches and sensory capsules. Development (1999) 2.19
EphB2 guides axons at the midline and is necessary for normal vestibular function. Neuron (2000) 2.13
Bidirectional signaling mediated by ephrin-B2 and EphB2 controls urorectal development. Dev Biol (2004) 2.08
Wnt signals mediate a fate decision between otic placode and epidermis. Development (2006) 1.94
Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh. Genes Dev (2005) 1.89
The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell (2001) 1.88
Cardiovascular ephrinB2 function is essential for embryonic angiogenesis. Development (2002) 1.84
Differential mitotic rates and patterns of growth in compartments in the Drosophila wing. Dev Biol (1981) 1.72
Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression. Cell (2009) 1.68
The large vestibular aqueduct syndrome. Laryngoscope (1978) 1.65
Visual map development: bidirectional signaling, bifunctional guidance molecules, and competition. Cold Spring Harb Perspect Biol (2010) 1.65
FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci (2000) 1.64
Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development (2003) 1.59
Transcriptional control of SLC26A4 is involved in Pendred syndrome and nonsyndromic enlargement of vestibular aqueduct (DFNB4). Am J Hum Genet (2007) 1.59
Functional significance of channels and transporters expressed in the inner ear and kidney. Am J Physiol Cell Physiol (2007) 1.57
Distal renal tubular acidosis in mice that lack the forkhead transcription factor Foxi1. J Clin Invest (2004) 1.53
Ephrins in reverse, park and drive. Trends Cell Biol (2002) 1.49
Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development. Dev Biol (2004) 1.47
Ephrins and Eph receptors in stem cells and cancer. Curr Opin Cell Biol (2010) 1.42
Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels. Am J Physiol Renal Physiol (2007) 1.37
EphB receptors regulate stem/progenitor cell proliferation, migration, and polarity during hippocampal neurogenesis. J Neurosci (2007) 1.36
Eph/ephrin signalling during development. Development (2012) 1.31
Immunolocalization of the Nuk receptor tyrosine kinase suggests roles in segmental patterning of the brain and axonogenesis. Oncogene (1994) 1.28
Localization and functional studies of pendrin in the mouse inner ear provide insight about the etiology of deafness in pendred syndrome. J Assoc Res Otolaryngol (2003) 1.27
Molecular mechanisms of cell segregation and boundary formation in development and tumorigenesis. Cold Spring Harb Perspect Biol (2012) 1.22
The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One (2009) 1.21
Fgf3 is required for dorsal patterning and morphogenesis of the inner ear epithelium. Development (2007) 1.21
Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model. Am J Physiol Renal Physiol (2007) 1.20
The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. Dev Biol (2002) 1.19
Patterning of the mammalian cochlea. Proc Natl Acad Sci U S A (2000) 1.19
Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev (2010) 1.17
Expression of mouse Foxi class genes in early craniofacial development. Dev Dyn (2004) 1.16
Cell proliferation and cell death in the developing chick inner ear: spatial and temporal patterns. J Comp Neurol (2000) 1.15
Development and maintenance of otoconia: biochemical considerations. Ann N Y Acad Sci (2001) 1.14
Mixing model systems: using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development. Brain Res (2006) 1.12
Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling. Development (2005) 1.12
Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. PLoS One (2011) 1.12
Foxi3 transcription factors and Notch signaling control the formation of skin ionocytes from epidermal precursors of the zebrafish embryo. Dev Biol (2007) 1.11
Hearing loss associated with enlargement of the vestibular aqueduct: mechanistic insights from clinical phenotypes, genotypes, and mouse models. Hear Res (2011) 1.11
Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression. PLoS One (2010) 1.09
Development of otoconia. Am J Otolaryngol (1980) 1.09
Rbpj regulates development of prosensory cells in the mammalian inner ear. Dev Biol (2011) 1.08
Calcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation. J Biol Chem (2010) 1.08
Specification of ion transport cells in the Xenopus larval skin. Development (2011) 1.08
Ephrin reverse signaling in axon guidance and synaptogenesis. Semin Cell Dev Biol (2011) 1.07
Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition. J Clin Invest (2011) 1.07
DAN directs endolymphatic sac and duct outgrowth in the avian inner ear. Dev Dyn (2004) 1.00
Molecular mechanisms underlying inner ear patterning defects in kreisler mutants. Dev Biol (2005) 1.00
EphB2 and ephrin-B2 regulate the ionic homeostasis of vestibular endolymph. Hear Res (2006) 0.99
Retinoic acid rescues inner ear defects in Hoxa1 deficient mice. Nat Genet (2001) 0.99
Co-expression of pendrin, vacuolar H+-ATPase alpha4-subunit and carbonic anhydrase II in epithelial cells of the murine endolymphatic sac. J Histochem Cytochem (2004) 0.97
Regulation of endolymphatic fluid volume. Ann N Y Acad Sci (2001) 0.95
Cell rearrangement and cell division during the tissue level morphogenesis of evaginating Drosophila imaginal discs. Dev Biol (2007) 0.93
SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice. PLoS Genet (2013) 0.92
Atp6v0a4 knockout mouse is a model of distal renal tubular acidosis with hearing loss, with additional extrarenal phenotype. Proc Natl Acad Sci U S A (2012) 0.92
Complementary and layered expression of Ephs and ephrins in developing mouse inner ear. J Comp Neurol (2002) 0.89
A fate map of chick otic cup closure reveals lineage boundaries in the dorsal otocyst. Dev Biol (2000) 0.89
Disruption of ephrin B/Eph B interaction results in abnormal cochlear innervation patterns. Laryngoscope (2011) 0.88
Auditory brainstem responses are impaired in EphA4 and ephrin-B2 deficient mice. Hear Res (2007) 0.87
SLC26A4 genotypes and phenotypes associated with enlargement of the vestibular aqueduct. Cell Physiol Biochem (2011) 0.87
Identification of direct downstream targets of Dlx5 during early inner ear development. Hum Mol Genet (2011) 0.83
Acidity in the endolymphatic sac fluid of guinea pigs. ORL J Otorhinolaryngol Relat Spec (1992) 0.82
Differences in endolymphatic sac mitochondria-rich cells indicate specific functions. Laryngoscope (2002) 0.82
An electron microscope study of crystal calcium carbonate formation in the mouse otolith. Anat Rec (1979) 0.81
Morphological changes of the endolymphatic sac induced by microinjection of artificial endolymph into the cochlea. Hear Res (1999) 0.81
Ionic and potential changes of the endolymphatic sac induced by endolymph volume changes. Hear Res (2000) 0.81
Mice deficient in H+-ATPase a4 subunit have severe hearing impairment associated with enlarged endolymphatic compartments within the inner ear. Dis Model Mech (2012) 0.80
Integration of human and mouse genetics reveals pendrin function in hearing and deafness. Cell Physiol Biochem (2011) 0.77
Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac. Ann Otol Rhinol Laryngol (1991) 0.76
Adult hepatocytes are generated by self-duplication rather than stem cell differentiation. Cell Stem Cell (2014) 1.88