miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages.

PubWeight™: 0.83‹?›

🔗 View Article (PMC 3996726)

Published in Biochim Biophys Acta on March 03, 2014

Authors

Manjula Vinod1, Indumathi Chennamsetty2, Sophie Colin3, Loic Belloy3, Federica De Paoli3, Helmut Schaider4, Wolfgang F Graier1, Saša Frank1, Dagmar Kratky1, Bart Staels3, Giulia Chinetti-Gbaguidi3, Gerhard M Kostner5

Author Affiliations

1: Institute of Molecular Biology and Biochemistry, Medical University of Graz, Austria.
2: Stanford Cardiovascular Medicine, Falk CVRC, USA.
3: Université Lille 2, F-59000 Lille, France; Inserm, U1011, F-59000 Lille, France; Institut Pasteur de Lille, F-59019 Lille, France; European Genomic Institute for Diabetes (EGID), FR 3508, F-59000 Lille, France.
4: Translation Research Institute, University of Queensland, Brisbane, Australia.
5: Institute of Molecular Biology and Biochemistry, Medical University of Graz, Austria. Electronic address: Gerhard.kostner@medunigraz.at.

Articles cited by this

MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59

Switching from repression to activation: microRNAs can up-regulate translation. Science (2007) 17.00

Atherosclerosis. Nature (2000) 15.95

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol (2011) 8.21

Role of LXRs in control of lipogenesis. Genes Dev (2000) 6.98

MiR-33 contributes to the regulation of cholesterol homeostasis. Science (2010) 6.93

AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell (2007) 5.87

Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest (2006) 4.92

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J Clin Invest (2011) 4.21

Bone Marrow-Derived Macrophages (BMM): Isolation and Applications. CSH Protoc (2008) 4.06

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol (2000) 3.58

MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo. Proc Natl Acad Sci U S A (2010) 3.00

MicroRNAs in disease and potential therapeutic applications. Mol Ther (2007) 2.73

MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells. Proc Natl Acad Sci U S A (2006) 2.15

Liver x receptor signaling pathways and atherosclerosis. Arterioscler Thromb Vasc Biol (2010) 1.79

Posttranscriptional upregulation by microRNAs. Wiley Interdiscip Rev RNA (2011) 1.73

MicroRNA-205-directed transcriptional activation of tumor suppressor genes in prostate cancer. Cancer (2010) 1.70

Liver X receptor activation stimulates iron export in human alternative macrophages. Circ Res (2013) 1.66

MicroRNA-758 regulates cholesterol efflux through posttranscriptional repression of ATP-binding cassette transporter A1. Arterioscler Thromb Vasc Biol (2011) 1.54

Immunologic detection and measurement of hypochlorite-modified LDL with specific monoclonal antibodies. Arterioscler Thromb Vasc Biol (1995) 1.32

Liver x receptors in atherosclerosis and inflammation. Circ Res (2011) 1.31

MicroRNA-144 regulates hepatic ATP binding cassette transporter A1 and plasma high-density lipoprotein after activation of the nuclear receptor farnesoid X receptor. Circ Res (2013) 1.30

Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144. Circ Res (2013) 1.25

MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7. FEBS Lett (2012) 1.18

MicroRNAs: emerging roles in lipid and lipoprotein metabolism. Curr Opin Lipidol (2012) 1.17

A KLF4-miRNA-206 autoregulatory feedback loop can promote or inhibit protein translation depending upon cell context. Mol Cell Biol (2011) 1.13

Trafficking of mature miRNA-122 into the nucleus of live liver cells. Curr Pharm Biotechnol (2009) 1.10

MicroRNA-mediated mRNA translation activation in quiescent cells and oocytes involves recruitment of a nuclear microRNP. Sci Rep (2012) 1.06

MicroRNA hsa-miR-613 targets the human LXRα gene and mediates a feedback loop of LXRα autoregulation. Mol Endocrinol (2011) 1.05

Serum albumin acts as a shuttle to enhance cholesterol efflux from cells. J Lipid Res (2013) 0.96

MicroRNA-1 and microRNA-206 suppress LXRα-induced lipogenesis in hepatocytes. Cell Signal (2013) 0.96

Lack of acyl-CoA:diacylglycerol acyltransferase 1 reduces intestinal cholesterol absorption and attenuates atherosclerosis in apolipoprotein E knockout mice. Biochim Biophys Acta (2011) 0.96

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation. J Lipid Res (2013) 0.92

Transcriptional and posttranscriptional control of cholesterol homeostasis by liver X receptors. Cold Spring Harb Symp Quant Biol (2011) 0.89

A minimal model for human whole body cholesterol metabolism. Am J Physiol (1993) 0.84

Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice. J Lipid Res (2012) 0.82