The metabolically healthy but obese phenotype is associated with lower plasma levels of persistent organic pollutants as compared to the metabolically abnormal obese phenotype.

PubWeight™: 1.48‹?› | Rank: Top 4%

🔗 View Article (PMID 24606089)

Published in J Clin Endocrinol Metab on February 25, 2014

Authors

Marie-Soleil Gauthier1, Rémi Rabasa-Lhoret, Denis Prud'homme, Antony D Karelis, Dawei Geng, Bert van Bavel, Jérôme Ruzzin

Author Affiliations

1: Institut de Recherches Cliniques de Montréal (M.-S.G., R.R.-L.), Montréal, Québec, H2W 1R7, Canada; Montreal Diabetes Research Centre at the Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM) (M.-S.G., R.R.-L.) Montréal, Québec, H1W 4A4, Canada; The Nutrition Department (R.R.-L.), Université de Montréal; the Endocrinology Division (R.R.-L.), Montreal University Hospital, Montréal, Québec, Canada H2W 1T8; School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, K1N 6N5, Canada; Institut de Recherche de l'Hôpital Montfort (D.P.), Ottawa, Ontario, K1K 0T2, Canada; Department of Kinanthropology (A.K.), Université du Québec à Montréal, Montréal, Québec, Canada H3C 3P8; MTM Research Center (D.G., B.v.B.), School of Science and Technology, Örebro University, SE-701 82 Örebro, Sweden; and Department of Biology (J.R.), University of Bergen, N-5006 Bergen, Norway.

Articles by these authors

Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial. Ann Intern Med (2007) 7.99

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem (2003) 3.45

The metabolically healthy but obese individual presents a favorable inflammation profile. J Clin Endocrinol Metab (2005) 3.21

Evaluation of a portable device to measure daily energy expenditure in free-living adults. Am J Clin Nutr (2007) 3.18

Managing obesity in adults in primary care. CMAJ (2012) 2.25

Barriers to physical activity among patients with type 1 diabetes. Diabetes Care (2008) 2.04

Glucose-responsive insulin and glucagon delivery (dual-hormone artificial pancreas) in adults with type 1 diabetes: a randomized crossover controlled trial. CMAJ (2013) 1.96

Increased concentrations of polychlorinated biphenyls, hexachlorobenzene, and chlordanes in mothers of men with testicular cancer. Environ Health Perspect (2003) 1.89

The effect of the menopausal transition on body composition and cardiometabolic risk factors: a Montreal-Ottawa New Emerging Team group study. Menopause (2012) 1.83

Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden. Environ Health Perspect (2006) 1.70

Circulating levels of persistent organic pollutants (POPs) and carotid atherosclerosis in the elderly. Environ Health Perspect (2012) 1.67

Polychlorinated biphenyls and organochlorine pesticides in plasma predict development of type 2 diabetes in the elderly: the prospective investigation of the vasculature in Uppsala Seniors (PIVUS) study. Diabetes Care (2011) 1.66

Characteristics of metabolically obese normal-weight (MONW) subjects. Appl Physiol Nutr Metab (2007) 1.65

The effect of topiramate on energy balance in obese men: a 6-month double-blind randomized placebo-controlled study with a 6-month open-label extension. Eur J Clin Pharmacol (2007) 1.54

Evidence for impaired lipolysis in abdominally obese men: postprandial study of apolipoprotein B-48- and B-100-containing lipoproteins. Am J Clin Nutr (2002) 1.49

Metabolic and behavioral characteristics of metabolically obese but normal-weight women. J Clin Endocrinol Metab (2004) 1.49

Personal air sampling and analysis of polybrominated diphenyl ethers and other bromine containing compounds at an electronic recycling facility in Sweden. J Environ Monit (2004) 1.46

European "REACH" (Registration, Evaluation, Authorisation and Restriction of Chemicals) program. J Chromatogr A (2008) 1.43

Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp. J Biol Chem (2003) 1.43

Effect of an Acute High Carbohydrate Diet on Body Composition Using DXA in Young Men. Ann Nutr Metab (2015) 1.38

Characterizing coronary heart disease risk in chronic schizophrenia: high prevalence of the metabolic syndrome. Can J Psychiatry (2004) 1.37

Metabolically healthy but obese individuals: relationship with hepatic enzymes. Metabolism (2009) 1.32

Identifying metabolically healthy but obese individuals in sedentary postmenopausal women. Obesity (Silver Spring) (2009) 1.30

Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction. Am J Clin Nutr (2009) 1.30

Adiponutrin gene is regulated by insulin and glucose in human adipose tissue. Eur J Endocrinol (2006) 1.28

The use of antiplatelet therapy in the outpatient setting: Canadian Cardiovascular Society guidelines. Can J Cardiol (2011) 1.25

The microRNA signature in response to insulin reveals its implication in the transcriptional action of insulin in human skeletal muscle and the role of a sterol regulatory element-binding protein-1c/myocyte enhancer factor 2C pathway. Diabetes (2009) 1.25

Evaluation of the Portable HealthWear Armband: a device to measure total daily energy expenditure in free-living type 2 diabetic individuals. Diabetes Care (2005) 1.24

Cardiometabolic risk in Canada: a detailed analysis and position paper by the cardiometabolic risk working group. Can J Cardiol (2011) 1.24

Prevention of type 2 diabetes: insulin resistance and beta-cell function. Diabetes (2004) 1.15

Physical activity is a confounding factor of the relation between eating frequency and body composition. Am J Clin Nutr (2008) 1.15

FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction. Diabetes (2010) 1.13

A multilevel analysis of neighbourhood built and social environments and adult self-reported physical activity and body mass index in Ottawa, Canada. Int J Environ Res Public Health (2011) 1.13

Struggle for quality in determination of perfluorinated contaminants in environmental and human samples. Environ Sci Technol (2006) 1.12

Menopause and sarcopenia: A potential role for sex hormones. Maturitas (2011) 1.10

Targets for glycemic control. Can J Diabetes (2013) 1.09

Adrenaline potentiates insulin-stimulated PKB activation via cAMP and Epac: implications for cross talk between insulin and adrenaline. Cell Signal (2005) 1.09

Effects of open-loop feedback on physical activity and television viewing in overweight and obese children: a randomized, controlled trial. Pediatrics (2006) 1.08

Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice. PLoS One (2011) 1.07

Analysis of continuous glucose monitoring data to assess outpatient closed-loop studies: considerations for different sensors. Diabetes Technol Ther (2014) 1.07

Video game playing is independently associated with blood pressure and lipids in overweight and obese adolescents. PLoS One (2011) 1.07

Surrogate measures of insulin sensitivity vs the hyperinsulinaemic-euglycaemic clamp: a meta-analysis. Are there not some surrogate indexes lost in this story? Diabetologia (2014) 1.06

Associations of persistent organic pollutants with abdominal obesity in the elderly: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Environ Int (2011) 1.06

Association of diabetes with anxiety: a systematic review and meta-analysis. J Psychosom Res (2012) 1.06

Levels of 12 perfluorinated chemicals in pooled australian serum, collected 2002-2003, in relation to age, gender, and region. Environ Sci Technol (2006) 1.05

Perfluorinated chemicals in relation to other persistent organic pollutants in human blood. Chemosphere (2006) 1.05

Effects of modifying physical activity and sedentary behavior on psychosocial adjustment in overweight/obese children. J Pediatr Psychol (2007) 1.05

Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation. J Clin Endocrinol Metab (2010) 1.04

Muscle glycogen inharmoniously regulates glycogen synthase activity, glucose uptake, and proximal insulin signaling. Am J Physiol Endocrinol Metab (2005) 1.04

Contribution of age and declining androgen levels to features of the metabolic syndrome in men. Metabolism (2005) 1.04

Exercise training decreases plasma leptin levels and the expression of hepatic leptin receptor-a, -b, and, -e in rats. Mol Cell Biochem (2008) 1.02

Association of cardiorespiratory fitness with insulin sensitivity in overweight and obese postmenopausal women: a Montreal Ottawa New Emerging Team study. Metabolism (2008) 1.01

Relationships between neighborhoods, physical activity, and obesity: a multilevel analysis of a large Canadian city. Obesity (Silver Spring) (2012) 1.00

Resistance training does not contribute to improving the metabolic profile after a 6-month weight loss program in overweight and obese postmenopausal women. J Clin Endocrinol Metab (2009) 1.00

Effect of exercise training on physical fitness in type II diabetes mellitus. Med Sci Sports Exerc (2010) 1.00

Relationship between sex hormone-binding globulin levels and features of the metabolic syndrome. Metabolism (2003) 0.98

Background exposure to persistent organic pollutants predicts stroke in the elderly. Environ Int (2012) 0.98

Circulating levels of persistent organic pollutants associate in divergent ways to fat mass measured by DXA in humans. Chemosphere (2011) 0.98

Anthropometric, metabolic, psychosocial, and dietary characteristics of overweight/obese postmenopausal women with a history of weight cycling: a MONET (Montreal Ottawa New Emerging Team) study. J Am Diet Assoc (2009) 0.97

Cystic fibrosis-related diabetes: from CFTR dysfunction to oxidative stress. Clin Biochem Rev (2009) 0.96

Evaluation of total lipids using enzymatic methods for the normalization of persistent organic pollutant levels in serum. Sci Total Environ (2006) 0.96

Identification and management of cardiometabolic risk in Canada: a position paper by the cardiometabolic risk working group (executive summary). Can J Cardiol (2011) 0.96

HDL particle size: a marker of the gender difference in the metabolic risk profile. Atherosclerosis (2002) 0.94

The interleukin 6-174G/C polymorphism is associated with indices of obesity in men. J Hum Genet (2003) 0.94

Relationship between the body adiposity index and cardiometabolic risk factors in obese postmenopausal women. Eur J Nutr (2012) 0.94

To be obese--does it matter if you are metabolically healthy? Nat Rev Endocrinol (2011) 0.93

Insulin regulation of gene expression and concentrations of white adipose tissue-derived proteins in vivo in healthy men: relation to adiponutrin. J Endocrinol (2006) 0.93

Acute hyperglycemia induces a global downregulation of gene expression in adipose tissue and skeletal muscle of healthy subjects. Diabetes (2007) 0.93

Adipose tissue concentrations of persistent organic pollutants and the risk of prostate cancer. J Occup Environ Med (2006) 0.92

Pharmacokinetic analysis of absorption, distribution and disappearance of ingested water labeled with D₂O in humans. Eur J Appl Physiol (2011) 0.92

Circulating levels of persistent organic pollutants in relation to visceral and subcutaneous adipose tissue by abdominal MRI. Obesity (Silver Spring) (2013) 0.92

The metabolically healthy but obese postmenopausal woman presents a favourable heart rate variability profile. Scand Cardiovasc J (2011) 0.91

Contribution of the lean body mass to insulin resistance in postmenopausal women with visceral obesity: a Monet study. Obesity (Silver Spring) (2008) 0.91

Postprandial hyperlipidemia: another correlate of the "hypertriglyceridemic waist" phenotype in men. Atherosclerosis (2003) 0.90

Time trends of persistent organic pollutants in Sweden during 1993-2007 and relation to age, gender, body mass index, breast-feeding and parity. Sci Total Environ (2010) 0.90

Association of acylated and nonacylated ghrelin with insulin sensitivity in overweight and obese postmenopausal women. J Clin Endocrinol Metab (2006) 0.90

A rapid method for screening of the Stockholm Convention POPs in small amounts of human plasma using SPE and HRGC/HRMS. Chemosphere (2011) 0.90

Analytical challenges hamper perfluoroalkyl research. Environ Sci Technol (2004) 0.89

Relationship between ghrelin and energy expenditure in healthy young women. J Clin Endocrinol Metab (2004) 0.89

A time trend study of significantly elevated perfluorocarboxylate levels in humans after using fluorinated ski wax. Environ Sci Technol (2010) 0.89

Top 10 practical lessons learned from physical activity interventions in overweight and obese children and adolescents. Appl Physiol Nutr Metab (2013) 0.89

Tumor necrosis factor alpha -238G>A genotype alters postprandial plasma levels of free fatty acids in obese individuals with type 2 diabetes mellitus. Metabolism (2007) 0.89

CFTR depletion results in changes in fatty acid composition and promotes lipogenesis in intestinal Caco 2/15 cells. PLoS One (2010) 0.89

The use of antiplatelet therapy in the outpatient setting: Canadian Cardiovascular Society Guidelines Executive Summary. Can J Cardiol (2011) 0.88

The Visceral Adiposity Index: Relationship with cardiometabolic risk factors in obese and overweight postmenopausal women--a MONET group study. Appl Physiol Nutr Metab (2013) 0.88

Biomonitoring perfluorinated compounds in Catalonia, Spain: concentrations and trends in human liver and milk samples. Environ Sci Pollut Res Int (2009) 0.88