Published in Nutrients on March 24, 2014
Nutraceuticals in cognitive impairment and Alzheimer's disease. Front Pharmacol (2014) 0.87
Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer. Mar Drugs (2015) 0.82
Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice. Lipids Health Dis (2015) 0.77
Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration. Geroscience (2017) 0.75
An Extract from Shrimp Processing By-Products Protects SH-SY5Y Cells from Neurotoxicity Induced by Aβ25-35. Mar Drugs (2017) 0.75
Effects of astaxanthin on oxidative stress induced by Cu(2+) in prostate cells. J Zhejiang Univ Sci B (2017) 0.75
Fish intake and the risk of brain tumor: a meta-analysis with systematic review. Nutr J (2017) 0.75
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13
Nuclear factor-kappaB in cancer development and progression. Nature (2006) 18.31
Alzheimer's disease: the amyloid cascade hypothesis. Science (1992) 13.80
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med (2001) 11.92
New regulators of NF-kappaB in inflammation. Nat Rev Immunol (2008) 5.79
Oxidative stress and neurodegeneration: where are we now? J Neurochem (2006) 5.44
Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem (1994) 5.11
Calcium regulation of neuronal gene expression. Proc Natl Acad Sci U S A (2001) 4.31
Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature (1995) 4.18
Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med (1997) 3.74
Metabolism and functions of glutathione in brain. Prog Neurobiol (2000) 3.74
NF-kappa B: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci (1997) 3.72
Inflammation and glial responses in ischemic brain lesions. Prog Neurobiol (1998) 2.84
Inflammation as a causative factor in the aetiology of Parkinson's disease. Br J Pharmacol (2007) 2.71
Roles for NF-kappaB in nerve cell survival, plasticity, and disease. Cell Death Differ (2006) 2.67
Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. Trends Mol Med (2001) 2.63
Oxidative stress and apoptosis. Pathophysiology (2000) 2.58
Haematococcus astaxanthin: applications for human health and nutrition. Trends Biotechnol (2003) 2.56
Neurodegenerative diseases and oxidative stress. Biomed Pharmacother (2004) 2.44
Docosahexaenoic acid: membrane properties of a unique fatty acid. Chem Phys Lipids (2003) 2.43
A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J Neurosci (2005) 2.36
Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med (2002) 2.35
Nrf2: a potential molecular target for cancer chemoprevention by natural compounds. Antioxid Redox Signal (2006) 2.22
Mitochondria, oxidative stress and neurodegeneration. J Neurol Sci (2012) 2.15
Resveratrol, a natural red wine polyphenol, reduces ischemia-reperfusion-induced spinal cord injury. Ann Thorac Surg (2005) 2.15
Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radic Biol Med (1990) 2.13
Dietary patterns and risk of dementia: the Three-City cohort study. Neurology (2007) 2.09
Lipid peroxidation in aging brain and Alzheimer's disease. Free Radic Biol Med (2002) 2.08
Carotenoid action on the immune response. J Nutr (2004) 2.01
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic Res (2002) 1.97
Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res (2002) 1.95
Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging (2002) 1.86
Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.86
Oxidative stress in Alzheimer's disease. Biochim Biophys Acta (2000) 1.84
Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease? Free Radic Biol Med (2008) 1.83
Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radic Biol Med (2009) 1.82
Nutrition in brain development and aging: role of essential fatty acids. Nutr Rev (2006) 1.81
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal (2010) 1.77
Antioxidants: Molecules, medicines, and myths. Biochem Biophys Res Commun (2010) 1.74
Metabolic effects of krill oil are essentially similar to those of fish oil but at lower dose of EPA and DHA, in healthy volunteers. Lipids (2010) 1.70
Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity. J Struct Biol (2000) 1.69
Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses. Trends Neurosci (2006) 1.67
Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy. J Neural Transm (Vienna) (2010) 1.66
Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis. Front Cell Neurosci (2013) 1.65
Color as a factor in food choice. Crit Rev Food Sci Nutr (1993) 1.62
Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr Res (2009) 1.55
Antioxidant therapies in traumatic brain and spinal cord injury. Biochim Biophys Acta (2011) 1.48
IANA task force on nutrition and cognitive decline with aging. J Nutr Health Aging (2007) 1.44
Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms. Redox Biol (2013) 1.42
Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection. Prog Neurobiol (2012) 1.41
Krill for human consumption: nutritional value and potential health benefits. Nutr Rev (2007) 1.40
Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation. Mol Cells (2003) 1.40
Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease. Biochim Biophys Acta (2010) 1.38
Oxidative stress in Alzheimer's disease. Pathophysiology (2006) 1.38
Mitochondrial structural and functional dynamics in Huntington's disease. Brain Res Rev (2009) 1.37
Omega-3 fatty acids improve recovery, whereas omega-6 fatty acids worsen outcome, after spinal cord injury in the adult rat. J Neurosci (2006) 1.37
Prognosis of Parkinson disease: risk of dementia and mortality: the Rotterdam Study. Arch Neurol (2005) 1.34
Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo. Invest Ophthalmol Vis Sci (2003) 1.32
Low glutathione and high iron govern the susceptibility of oligodendroglial precursors to oxidative stress. J Neurochem (1996) 1.32
Antioxidant and prooxidant properties of carotenoids. Arch Biochem Biophys (2001) 1.32
Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease. Eur J Neurosci (2005) 1.30
Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans. Nutr Metab (Lond) (2010) 1.29
Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation. Curr Pharm Des (2006) 1.26
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Targets (2007) 1.24
Oxidative stress-related biomarkers in autism: systematic review and meta-analyses. Free Radic Biol Med (2012) 1.24
Dietary effects on brain fatty acid composition: the reversibility of n-3 fatty acid deficiency and turnover of docosahexaenoic acid in the brain, erythrocytes, and plasma of rhesus monkeys. J Lipid Res (1990) 1.22
Innovative dietary sources of n-3 fatty acids. Annu Rev Nutr (2006) 1.21
Docosahexaenoic acid and the aging brain. J Nutr (2008) 1.20
Beneficial effects of dietary omega-3 polyunsaturated fatty acid on toxin-induced neuronal degeneration in an animal model of Parkinson's disease. FASEB J (2007) 1.20
Role of oxidative stress in epileptic seizures. Neurochem Int (2011) 1.20
Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid beta-infused rats. J Nutr (2005) 1.19
Dysregulated relationship of inflammation and oxidative stress in major depression. Brain Behav Immun (2012) 1.18
Neuroprotective action of omega-3 polyunsaturated fatty acids against neurodegenerative diseases: evidence from animal studies. Prostaglandins Leukot Essent Fatty Acids (2007) 1.17
Mitochondria as a therapeutic target for aging and neurodegenerative diseases. Curr Alzheimer Res (2011) 1.17
An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res Brain Res Rev (1999) 1.17
Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin. Stroke (2005) 1.15
Oxygen toxicity: chemistry and biology of reactive oxygen species. Semin Fetal Neonatal Med (2010) 1.14
Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6). J Neurochem (1991) 1.14
Evaluation of the effect of Neptune Krill Oil on chronic inflammation and arthritic symptoms. J Am Coll Nutr (2007) 1.12
Fish, docosahexaenoic acid and Alzheimer's disease. Prog Lipid Res (2009) 1.11
Immunomodulating actions of carotenoids: enhancement of in vivo and in vitro antibody production to T-dependent antigens. Nutr Cancer (1994) 1.10
Activation of macrophages by Alzheimer beta amyloid peptide. Biochem Biophys Res Commun (1994) 1.10
Essential fatty acids and the brain: from infancy to aging. Neurobiol Aging (2005) 1.09
Inflammatory responses in hypoxic ischemic encephalopathy. Acta Pharmacol Sin (2013) 1.07
Depression in Parkinson's disease: a double-blind, randomized, placebo-controlled pilot study of omega-3 fatty-acid supplementation. J Affect Disord (2008) 1.07
Response of glial cells to ischemia: roles of reactive oxygen species and glutathione. Neurosci Biobehav Rev (1997) 1.07
Astaxanthin protects mitochondrial redox state and functional integrity against oxidative stress. J Nutr Biochem (2009) 1.06
Glial cell type-specific responses to menadione-induced oxidative stress. Free Radic Biol Med (2000) 1.06
The protective effect of fish n-3 fatty acids on cerebral ischemia in rat hippocampus. Neurochem Int (2006) 1.05
Antioxidant nutrients and hypoxia/ischemia brain injury in rodents. Toxicology (2003) 1.05
Astaxanthin protects ARPE-19 cells from oxidative stress via upregulation of Nrf2-regulated phase II enzymes through activation of PI3K/Akt. Mol Vis (2013) 1.04
A diet high in omega-3 fatty acids does not improve or protect cognitive performance in Alzheimer's transgenic mice. Neuroscience (2007) 1.03
Effects of n-3 and n-6 fatty acids on the activities and expression of hepatic antioxidant enzymes in autoimmune-prone NZBxNZW F1 mice. Lipids (1994) 1.03
Omega-3 fatty acids, energy substrates, and brain function during aging. Prostaglandins Leukot Essent Fatty Acids (2006) 1.02
Age-associated changes in central nervous system glycerolipid composition and metabolism. Neurochem Res (2002) 1.02
Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. Eur J Nutr (2012) 1.01
Omega-3 fatty acids: potential role in the management of early Alzheimer's disease. Clin Interv Aging (2010) 1.01
Neuroprotective effect of astaxanthin on H(2)O(2)-induced neurotoxicity in vitro and on focal cerebral ischemia in vivo. Brain Res (2010) 1.01
Astaxanthin induces mitochondria-mediated apoptosis in rat hepatocellular carcinoma CBRH-7919 cells. Biol Pharm Bull (2011) 1.01
Contribution of the antioxidative property of astaxanthin to its protective effect on the promotion of cancer metastasis in mice treated with restraint stress. Life Sci (2002) 1.01