Oxidative imbalance and anxiety disorders.

PubWeight™: 0.82‹?›

🔗 View Article (PMC 3964749)

Published in Curr Neuropharmacol on March 01, 2014

Authors

Krolow R1, Arcego D M1, Noschang C1, Weis S N1, Dalmaz C1

Author Affiliations

1: Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, UFRGS, Porto Alegre, Rio Grande do Sul, Brazil.

Articles cited by this

(truncated to the top 100)

Oxidants, oxidative stress and the biology of ageing. Nature (2000) 23.21

Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol (2006) 21.58

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med (1991) 16.01

Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49

Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev (2007) 11.15

Oxidative stress and neurodegeneration: where are we now? J Neurochem (2006) 5.44

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet (2000) 5.42

Metabolism and functions of glutathione in brain. Prog Neurobiol (2000) 3.74

Neurotrophin regulation of neural circuit development and function. Nat Rev Neurosci (2013) 3.53

Glucocorticoid receptors in major depression: relevance to pathophysiology and treatment. Biol Psychiatry (2001) 3.39

The cellular neurobiology of depression. Nat Med (2001) 3.19

Posttraumatic stress disorder and physical illness: results from clinical and epidemiologic studies. Ann N Y Acad Sci (2004) 3.02

NF-kappaB in neuronal plasticity and neurodegenerative disorders. J Clin Invest (2001) 2.78

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders. Nat Rev Drug Discov (2010) 2.68

A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis. Oncogene (2002) 2.55

The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death. Biol Psychiatry (2000) 2.53

Free radicals and antioxidants in the year 2000. A historical look to the future. Ann N Y Acad Sci (2000) 2.47

Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior. Proc Natl Acad Sci U S A (2008) 2.35

Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice. Nature (2005) 2.29

Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation. Antioxid Redox Signal (2010) 2.26

Stress and health: psychological, behavioral, and biological determinants. Annu Rev Clin Psychol (2005) 2.19

The developmental origins of anxiety. Nat Rev Neurosci (2004) 2.17

Mitochondria and calcium signaling. Cell Calcium (2005) 2.08

Mitochondrial diseases. Lancet (2012) 2.08

Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments. J Affect Disord (2001) 1.99

Phospholipase A2 in the central nervous system: implications for neurodegenerative diseases. J Lipid Res (2003) 1.92

Enigma of the peripheral benzodiazepine receptor. Pharmacol Rev (1999) 1.92

Voluntary exercise produces antidepressant and anxiolytic behavioral effects in mice. Brain Res (2008) 1.84

Peripheral benzodiazepine receptors and mitochondrial function. Neurochem Int (2002) 1.82

Mitochondria and degenerative disorders. Am J Med Genet (2001) 1.81

Oxygen free radicals and brain dysfunction. Int J Neurosci (1991) 1.79

Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer. J Neuroimmune Pharmacol (2006) 1.74

Interferon-alpha effects on diurnal hypothalamic-pituitary-adrenal axis activity: relationship with proinflammatory cytokines and behavior. Mol Psychiatry (2008) 1.73

Mitochondrial dysfunction and psychiatric disorders. Neurochem Res (2008) 1.73

Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Curr Opin Clin Nutr Metab Care (2007) 1.62

A short review on the psychoneuroimmunology of posttraumatic stress disorder: from risk factors to medical comorbidities. Brain Behav Immun (2010) 1.61

Brain-derived neurotrophic factor: a dynamic gatekeeper of neural plasticity. Curr Mol Pharmacol (2010) 1.57

GABA(A) receptor-modulating neuroactive steroid composition in patients with panic disorder before and during paroxetine treatment. Am J Psychiatry (2002) 1.56

Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis. J Pharmacol Exp Ther (2007) 1.55

Cerebral blood flow in subjects with social phobia during stressful speaking tasks: a PET study. Am J Psychiatry (2001) 1.52

Oxidative damage and major depression: the potential antioxidant action of selective serotonin re-uptake inhibitors. Redox Rep (2003) 1.51

Roles of mitophagy and the mitochondrial permeability transition in remodeling of cultured rat hepatocytes. Autophagy (2009) 1.49

Depression, stress and immunological activation: the role of cytokines in depressive disorders. Life Sci (1998) 1.44

A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. PLoS One (2009) 1.44

Hypocortisolism and increased glucocorticoid sensitivity of pro-Inflammatory cytokine production in Bosnian war refugees with posttraumatic stress disorder. Biol Psychiatry (2004) 1.43

High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal cortex. J Clin Invest (2002) 1.41

Dicarbonyl intermediates in the maillard reaction. Ann N Y Acad Sci (2005) 1.41

Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety. J Neurosci (2005) 1.40

Mitochondrial involvement in psychiatric disorders. Ann Med (2008) 1.38

Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice. J Pharmacol Exp Ther (2008) 1.38

Dynamic regulation of mitochondrial function by glucocorticoids. Proc Natl Acad Sci U S A (2009) 1.38

Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat. Brain Res (1992) 1.37

Voluntary exercise induces anxiety-like behavior in adult C57BL/6J mice correlating with hippocampal neurogenesis. Hippocampus (2010) 1.37

Chronic NF-{kappa}B blockade reduces cytosolic and mitochondrial oxidative stress and attenuates renal injury and hypertension in SHR. Am J Physiol Renal Physiol (2008) 1.37

Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response. Curr Pharm Des (2007) 1.36

Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid. J Neurochem (2008) 1.35

PTSD is associated with an excess of inflammatory immune activities. Perspect Psychiatr Care (2009) 1.34

Clinical anxiety, cortisol and interleukin-6: evidence for specificity in emotion-biology relationships. Brain Behav Immun (2010) 1.31

Oxidative stress and anxiety: relationship and cellular pathways. Oxid Med Cell Longev (2010) 1.30

Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in rats. Behav Brain Res (2010) 1.30

Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors. J Neurosci (2010) 1.30

Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments. Brain Res (2008) 1.28

The psychoneuroimmunology of depression. Hum Psychopharmacol (2009) 1.28

Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma. Exp Neurol (2009) 1.26

Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD. J Trauma Stress (2008) 1.25

Oxidative stress in anxiety and comorbid disorders. Neurosci Res (2010) 1.24

Differential gene expression in peripheral blood of patients suffering from post-traumatic stress disorder. Mol Psychiatry (2007) 1.23

Mitochondrial respiratory chain and free radical generation in stroke. Free Radic Biol Med (2005) 1.23

Highly palatable diet consumption increases protein oxidation in rat frontal cortex and anxiety-like behavior. Life Sci (2007) 1.19

Short-term glucocorticoid manipulations affect neuronal morphology and survival in the adult dentate gyrus. Neuroscience (1990) 1.15

Proteomics and metabolomics analysis of a trait anxiety mouse model reveals divergent mitochondrial pathways. Biol Psychiatry (2011) 1.14

Effects of beta-adrenoreceptor blockade during chronic exercise on contextual fear conditioning and mRNA for galanin and brain-derived neurotrophic factor. Behav Neurosci (2004) 1.14

Evidence that oxidative stress is linked to anxiety-related behaviour in mice. Brain Behav Immun (2008) 1.12

A comparative study of superoxide dismutase, catalase, and glutathione peroxidase activities and nitrate levels in vitiligo patients. Int J Dermatol (2005) 1.12

Oxidative stress: a potential recipe for anxiety, hypertension and insulin resistance. Brain Res (2010) 1.11

Dynamic plasticity: the role of glucocorticoids, brain-derived neurotrophic factor and other trophic factors. Neuroscience (2012) 1.10

Neuronal nitric oxide synthase knock-out mice show impaired cognitive performance. Nitric Oxide (2004) 1.09

Neural regulation of the stress response: glucocorticoid feedback mechanisms. Braz J Med Biol Res (2012) 1.07

Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment. Pharmacol Rep (2009) 1.07

Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex. Can J Biochem Cell Biol (1983) 1.07

Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors. J Neurosci (2010) 1.07

Cell culture models of oxidative stress and injury in the central nervous system. Curr Neurovasc Res (2005) 1.06

Glutathione and free sulphydryl content of seminal plasma in healthy medical students during and after exam stress. Hum Reprod (2005) 1.06

Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. J Clin Invest (2012) 1.06

Impairment of several immune functions in anxious women. J Psychosom Res (2007) 1.05

Potential contribution of oxidative stress and inflammation to anxiety and hypertension. Brain Res (2011) 1.05

Positive correlation between peripheral blood granulocyte oxidative status and level of anxiety in mice. Eur J Pharmacol (2007) 1.05

Inflammatory biomarkers in patients with posttraumatic stress disorder caused by myocardial infarction and the role of depressive symptoms. Neuroimmunomodulation (2009) 1.04

Plasma levels of tumor necrosis factor-alpha and interleukin-6 in obsessive compulsive disorder. Mediators Inflamm (2007) 1.04

Activation of peripheral mitochondrial benzodiazepine receptors in the hippocampus stimulates allopregnanolone synthesis and produces anxiolytic-like effects in the rat. Psychopharmacology (Berl) (2000) 1.04

Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity. J Neurosci Res (2005) 1.03

Distribution of the uncoupling protein 2 mRNA in the mouse brain. J Comp Neurol (1998) 1.03

Phospholipid transfer protein (PLTP) deficiency reduces brain vitamin E content and increases anxiety in mice. FASEB J (2004) 1.03

The anxiolytic etifoxine activates the peripheral benzodiazepine receptor and increases the neurosteroid levels in rat brain. Pharmacol Biochem Behav (2006) 1.03

Antioxidative enzymes and increased oxidative stress in depressive women. Clin Biochem (2009) 1.02

Protective effect of alprazolam in acute immobilization stress-induced certain behavioral and biochemical alterations in mice. Pharmacol Rep (2007) 1.02

Glucocorticoids exacerbate kainic acid-induced extracellular accumulation of excitatory amino acids in the rat hippocampus. J Neurochem (1992) 1.01

Glucocorticoid regulation of brain-derived neurotrophic factor: relevance to hippocampal structural and functional plasticity. Neuroscience (2012) 1.01

Disturbed emotionality in autoimmune MRL-lpr mice. Physiol Behav (1994) 1.00

Decreased TNF-alpha and NK activity in obsessive-compulsive disorder. Psychoneuroendocrinology (2004) 1.00