Published in J Ind Microbiol Biotechnol on March 30, 2014
Development of a fed-batch process for a recombinant Pichia pastoris Δoch1 strain expressing a plant peroxidase. Microb Cell Fact (2015) 0.91
Heterologous protein production using the Pichia pastoris expression system. Yeast (2005) 3.85
Strategies and challenges for the next generation of therapeutic antibodies. Nat Rev Immunol (2010) 3.70
Expression of heterologous proteins in Pichia pastoris: a useful experimental tool in protein engineering and production. J Mol Recognit (2005) 2.83
Engineered protein scaffolds as next-generation antibody therapeutics. Curr Opin Chem Biol (2009) 2.41
Alternative non-antibody scaffolds for molecular recognition. Curr Opin Biotechnol (2007) 1.93
Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview. Microb Cell Fact (2008) 1.89
Protein secretion in Pichia pastoris and advances in protein production. Appl Microbiol Biotechnol (2011) 1.61
Production of monoclonal antibodies by glycoengineered Pichia pastoris. J Biotechnol (2008) 1.36
Low-temperature increases the yield of biologically active herring antifreeze protein in Pichia pastoris. Protein Expr Purif (2001) 1.24
Enhancement of protein secretion in Pichia pastoris by overexpression of protein disulfide isomerase. Biotechnol Bioeng (2006) 1.16
Engineered protein scaffolds for molecular recognition. J Mol Recognit (2000) 1.15
Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae. Pharm Res (2006) 1.01
An optimized fermentation process for high-level production of a single-chain Fv antibody fragment in Pichia pastoris. Protein Expr Purif (2004) 1.00
Recombinant antibodies: engineering and production in yeast and bacterial hosts. Biotechnol J (2011) 0.96
Homomeric and heteromeric interactions of the extracellular domains of death receptors and death decoy receptors. Biochem Biophys Res Commun (2005) 0.94
Optimal conditions for the expression of a single-chain antibody (scFv) gene in Pichia pastoris. Protein Expr Purif (2003) 0.93
Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen. Microb Cell Fact (2009) 0.91
Enhancing the production of Fc fusion protein in fed-batch fermentation of Pichia pastoris by design of experiments. Biotechnol Prog (2007) 0.90
Optimization of a glycoengineered Pichia pastoris cultivation process for commercial antibody production. Biotechnol Prog (2011) 0.88
Strategies for production of active eukaryotic proteins in bacterial expression system. Asian Pac J Trop Biomed (2012) 0.86
Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. J Biol Chem (2011) 0.84
Replacing antibodies: engineering new binding proteins. Annu Rev Biomed Eng (2013) 0.83
High-level expression of Staphylococcal Protein A in Pichia pastoris and purification and characterization of the recombinant protein. Protein Expr Purif (2013) 0.80
Engineering of a human kringle domain into agonistic and antagonistic binding proteins functioning in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 0.78
Comparative analysis of chimpanzee and human Y chromosomes unveils complex evolutionary pathway. Nat Genet (2006) 3.76
Identification of serum microRNAs as novel non-invasive biomarkers for early detection of gastric cancer. PLoS One (2012) 1.66
Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells. Clin Cancer Res (2005) 1.63
Differences in gastric mucosal microbiota profiling in patients with chronic gastritis, intestinal metaplasia, and gastric cancer using pyrosequencing methods. Helicobacter (2014) 1.59
Superior mesenteric artery syndrome: where do we stand today? J Gastrointest Surg (2012) 1.59
Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli-expressed libraries. Proc Natl Acad Sci U S A (2004) 1.54
Epigenomic analysis of aberrantly methylated genes in colorectal cancer identifies genes commonly affected by epigenetic alterations. Ann Surg Oncol (2011) 1.50
Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma. Clin Cancer Res (2009) 1.31
Organizational and mutational analysis of a complete FR-008/candicidin gene cluster encoding a structurally related polyene complex. Chem Biol (2003) 1.27
Gene expression profiling of human HBV- and/or HCV-associated hepatocellular carcinoma cells using expressed sequence tags. Int J Oncol (2006) 1.26
Combined transcriptome and proteome analysis of Escherichia coli during high cell density culture. Biotechnol Bioeng (2003) 1.24
Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion. Carcinogenesis (2008) 1.24
Realization of a near-perfect antireflection coating for silicon solar energy utilization. Opt Lett (2008) 1.22
Collagen triple helix repeat containing 1 (CTHRC1) acts via ERK-dependent induction of MMP9 to promote invasion of colorectal cancer cells. Oncotarget (2014) 1.20
Epigenetic regulation of microRNA-10b and targeting of oncogenic MAPRE1 in gastric cancer. Epigenetics (2011) 1.19
Genome-wide association of serum bilirubin levels in Korean population. Hum Mol Genet (2010) 1.10
A genome-wide scan for the Sasang constitution in a Korean family suggests significant linkage at chromosomes 8q11.22-23 and 11q22.1-3. J Altern Complement Med (2009) 1.08
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage. Hum Mol Genet (2013) 1.08
Association of serum alanine aminotransferase and γ-glutamyltransferase levels within the reference range with metabolic syndrome and nonalcoholic fatty liver disease. Korean J Hepatol (2011) 1.07
Quality of life of patients with irritable bowel syndrome in Korea. Qual Life Res (2009) 1.05
Cytotoxic dammarane glycosides from processed ginseng. Chem Pharm Bull (Tokyo) (2002) 1.05
H2B monoubiquitylation is a 5'-enriched active transcription mark and correlates with exon-intron structure in human cells. Genome Res (2012) 1.02
Gene expression analysis of cultured amniotic fluid cell with Down syndrome by DNA microarray. J Korean Med Sci (2005) 1.02
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination. Proc Natl Acad Sci U S A (2009) 1.01
MENT: methylation and expression database of normal and tumor tissues. Gene (2012) 1.01
Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. Biochem Biophys Res Commun (2006) 1.01
Beyond toothpicks: new methods for isolating mutant bacteria. Nat Rev Microbiol (2007) 1.00
Elevated red cell distribution width is associated with advanced fibrosis in NAFLD. Clin Mol Hepatol (2013) 1.00
Quantitative analysis of cell-free DNA in the plasma of gastric cancer patients. Oncol Lett (2012) 0.98
Esophageal bezoar in a patient with achalasia: case report and literature review. Gut Liver (2010) 0.98
Role of FLASH in caspase-8-mediated activation of NF-kappaB: dominant-negative function of FLASH mutant in NF-kappaB signaling pathway. Oncogene (2005) 0.97
Meta- and gene set analysis of stomach cancer gene expression data. Mol Cells (2007) 0.96
Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis. Apoptosis (2013) 0.96
Combined hypermethylation and chromosome loss associated with inactivation of SSI-1/SOCS-1/JAB gene in human hepatocellular carcinomas. Cancer Lett (2002) 0.94
Diagnostic value of the anterior chamber depth of a globe on CT for detecting open-globe injury. Eur Radiol (2009) 0.94
Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression. Cancer Lett (2006) 0.93
A gene sets approach for identifying prognostic gene signatures for outcome prediction. BMC Genomics (2008) 0.93
Integrative genomics analysis reveals the multilevel dysregulation and oncogenic characteristics of TEAD4 in gastric cancer. Carcinogenesis (2013) 0.93
Aberrant up-regulation of LAMB3 and LAMC2 by promoter demethylation in gastric cancer. Biochem Biophys Res Commun (2011) 0.92
Membrane topology of helix 0 of the Epsin N-terminal homology domain. Mol Cells (2006) 0.92
Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion. Mol Cancer Res (2008) 0.92
nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer. Oncotarget (2014) 0.92
The epigenetic silencing of LIMS2 in gastric cancer and its inhibitory effect on cell migration. Biochem Biophys Res Commun (2006) 0.92
Active doping of B in silicon nanostructures and development of a Si quantum dot solar cell. Nanotechnology (2011) 0.92
Frequent silencing of popeye domain-containing genes, BVES and POPDC3, is associated with promoter hypermethylation in gastric cancer. Carcinogenesis (2010) 0.92
Identification of novel genes associated with the response to 5-FU treatment in gastric cancer cell lines using a cDNA microarray. Cancer Lett (2004) 0.92
Pyruvate kinase M2 promotes the growth of gastric cancer cells via regulation of Bcl-xL expression at transcriptional level. Biochem Biophys Res Commun (2012) 0.91
SERPINE1 intron polymorphisms affecting gene expression are associated with diffuse-type gastric cancer susceptibility. Cancer (2010) 0.91
Evaluation of intracellular lipid bodies in Chlamydomonas reinhardtii strains by flow cytometry. Bioresour Technol (2013) 0.91
Effects of mechanical stimuli and microfiber-based substrate on neurite outgrowth and guidance. J Biosci Bioeng (2006) 0.91
Human histone H3K79 methyltransferase DOT1L protein [corrected] binds actively transcribing RNA polymerase II to regulate gene expression. J Biol Chem (2012) 0.91
Vitamin C down-regulates VEGF production in B16F10 murine melanoma cells via the suppression of p42/44 MAPK activation. J Cell Biochem (2011) 0.90
Lacrimal silicone intubation for anatomically successful but functionally failed external dacryocystorhinostomy. Korean J Ophthalmol (2007) 0.90
Isolation of fully synthetic promoters for high-level gene expression in Corynebacterium glutamicum. Biotechnol Bioeng (2013) 0.90
Elevated fibroblast growth factor-inducible 14 expression promotes gastric cancer growth via nuclear factor-κB and is associated with poor patient outcome. Cancer Lett (2011) 0.89
Upregulation of SPRR3 promotes colorectal tumorigenesis. Mol Med (2010) 0.89
Engineering Escherichia coli for increased productivity of serine-rich proteins based on proteome profiling. Appl Environ Microbiol (2003) 0.89
An improved method for constructing a full-length enriched cDNA library using small amounts of total RNA as a starting material. Exp Mol Med (2003) 0.89
LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer. Cancer Res (2008) 0.88
Biological responses of ligament fibroblasts and gene expression profiling on micropatterned silicone substrates subjected to mechanical stimuli. J Biosci Bioeng (2006) 0.88
Binding and enrichment of Escherichia coli spheroplasts expressing inner membrane tethered scFv antibodies on surface immobilized antigens. Biotechnol Bioeng (2007) 0.88
Engineering of protease variants exhibiting altered substrate specificity. Biochem Biophys Res Commun (2008) 0.88
Thyrotoxic vomiting: a case report and possible mechanisms. J Neurogastroenterol Motil (2010) 0.87
Epigenetic modification of retinoic acid-treated human embryonic stem cells. BMB Rep (2010) 0.87
Optic neuritis in Asian children. J Pediatr Ophthalmol Strabismus (2002) 0.87
CpG methylation in exon 1 of transcription factor 4 increases with age in normal gastric mucosa and is associated with gene silencing in intestinal-type gastric cancers. Carcinogenesis (2008) 0.86
Copy number variations (CNVs) identified in Korean individuals. BMC Genomics (2008) 0.86
Oncogenic effect of Polo-like kinase 1 expression in human gastric carcinomas. Int J Oncol (2006) 0.86
Growth and invasion of sporadic colorectal adenocarcinomas in terms of genetic change. J Korean Med Sci (2010) 0.85
Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells. Cancer Sci (2013) 0.85
Gene cataloging and expression profiling in human gastric cancer cells by expressed sequence tags. Genomics (2004) 0.85
Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity. Exp Mol Med (2008) 0.85
Expression of SPRR3 is associated with tumor cell proliferation in less advanced stages of breast cancer. Breast Cancer Res Treat (2011) 0.84
High-level secretory production of recombinant single-chain variable fragment (scFv) in Corynebacterium glutamicum. Appl Microbiol Biotechnol (2013) 0.84
The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β. PLoS One (2010) 0.84
Genetic variants A1826H and D2937Y in GAG-beta domain of versican influence susceptibility to intestinal-type gastric cancer. J Cancer Res Clin Oncol (2009) 0.84
Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. J Biol Chem (2011) 0.84
Transcriptome analysis of human gastric cancer. Mamm Genome (2005) 0.84
Inhibitory activity of ginsenosides isolated from processed ginseng on platelet aggregation. Pharmazie (2010) 0.84
Epigenetic alteration of CCDC67 and its tumor suppressor function in gastric cancer. Carcinogenesis (2012) 0.84
Rifabutin-based high-dose proton-pump inhibitor and amoxicillin triple regimen as the rescue treatment for Helicobacter pylori. Helicobacter (2014) 0.83
A regulatory polymorphism at position -309 in PTPRCAP is associated with susceptibility to diffuse-type gastric cancer and gene expression. Neoplasia (2009) 0.83
[The prevalence of atrophic gastritis and intestinal metaplasia according to gender, age and Helicobacter pylori infection in a rural population]. J Prev Med Public Health (2008) 0.83
Development of potent inhibitors of the coxsackievirus 3C protease. Biochem Biophys Res Commun (2007) 0.83
Cofactor-free light-driven whole-cell cytochrome P450 catalysis. Angew Chem Int Ed Engl (2014) 0.83
Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer. Int J Cancer (2011) 0.82
In vitro chemosensitivity of gastric adenocarcinomas to histone deacetylase inhibitors, compared to established drugs. Hepatogastroenterology (2010) 0.82
Medical history and lifestyle factors contributing to Epstein-Barr virus-associated gastric carcinoma and conventional gastric carcinoma in Korea. Anticancer Res (2010) 0.82
Microarray screening and qRT-PCR evaluation of microRNA markers for forensic body fluid identification. Electrophoresis (2014) 0.82
Development of a secretion system for the production of heterologous proteins in Corynebacterium glutamicum using the Porin B signal peptide. Protein Expr Purif (2013) 0.81
TNFR1 promoter -329G/T polymorphism results in allele-specific repression of TNFR1 expression. Biochem Biophys Res Commun (2008) 0.81
Quantified high-throughput screening of Escherichia coli producing poly(3-hydroxybutyrate) based on FACS. Appl Biochem Biotechnol (2013) 0.81
A patient with tuberculous peritonitis with very high serum CA 125. BMJ Case Rep (2012) 0.81
Optimized stability retention of a monoclonal antibody in the PLGA nanoparticles. Int J Pharm (2008) 0.81
Genetic susceptibility on CagA-interacting molecules and gene-environment interaction with phytoestrogens: a putative risk factor for gastric cancer. PLoS One (2012) 0.81
An engineered viral protease exhibiting substrate specificity for a polyglutamine stretch prevents polyglutamine-induced neuronal cell death. PLoS One (2011) 0.81
[Association between diverticulosis and colonic Neoplasm in Koreans]. Korean J Gastroenterol (2007) 0.81
CaGe: A Web-Based Cancer Gene Annotation System for Cancer Genomics. Genomics Inform (2012) 0.81
Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study. PLoS One (2011) 0.80
Engineering antibody fragments to fold in the absence of disulfide bonds. Protein Sci (2009) 0.80