Proteases and Delayed Wound Healing.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 24688830)

Published in Adv Wound Care (New Rochelle) on October 01, 2013

Authors

Sara M McCarty1, Steven L Percival2

Author Affiliations

1: Institute of Ageing and Chronic Disease, University of Liverpool , Liverpool, United Kingdom .
2: Scapa Healthcare , Ashton under Lyne, United Kingdom .

Associated clinical trials:

Prontosan Quality of Life Study in Patients With Chronic Leg Wound(s) | NCT03369756

Articles citing this

Challenges in the Treatment of Chronic Wounds. Adv Wound Care (New Rochelle) (2015) 0.97

Current strategies and findings in clinically relevant post-translational modification-specific proteomics. Expert Rev Proteomics (2015) 0.83

Porous hyaluronic acid hydrogels for localized nonviral DNA delivery in a diabetic wound healing model. Adv Healthc Mater (2015) 0.82

Topical Collagen-Based Biomaterials for Chronic Wounds: Rationale and Clinical Application. Adv Wound Care (New Rochelle) (2016) 0.81

Matrix metalloproteinase 9 modulates collagen matrices and wound repair. Development (2015) 0.80

Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine. J Transl Med (2016) 0.80

Engineered Biopolymeric Scaffolds for Chronic Wound Healing. Front Physiol (2016) 0.78

An Enzyme from Aristolochia indica Destabilizes Fibrin-β Amyloid Co-Aggregate: Implication in Cerebrovascular Diseases. PLoS One (2015) 0.77

In vivo assessment of protease dynamics in cutaneous wound healing by degradomics analysis of porcine wound exudates. Mol Cell Proteomics (2014) 0.77

Challenges and Opportunities in Drug Delivery for Wound Healing. Adv Wound Care (New Rochelle) (2016) 0.76

Syndesome Therapeutics for Enhancing Diabetic Wound Healing. Adv Healthc Mater (2016) 0.76

A Formidable Foe Is Sabotaging Your Results: What You Should Know about Biofilms and Wound Healing. Plast Reconstr Surg (2017) 0.75

Spot the difference: Solving the puzzle of hidden pictures in the lizard genome for identification of regeneration factors. BMB Rep (2016) 0.75

Modulation of inflammatory response of wounds by antimicrobial photodynamic therapy. Laser Ther (2015) 0.75

Identification and Characterization of Novel Matrix-Derived Bioactive Peptides: A Role for Collagenase from Santyl® Ointment in Post-Debridement Wound Healing? PLoS One (2016) 0.75

The Role of Matrix Metalloproteinases in Diabetic Wound Healing in relation to Photobiomodulation. J Diabetes Res (2016) 0.75

The Influence of Chronic Wound Extracts on Inflammatory Cytokine and Histatin Stability. PLoS One (2016) 0.75

Articles cited by this

Wound healing: an overview of acute, fibrotic and delayed healing. Front Biosci (2004) 5.59

Inflammation in wound repair: molecular and cellular mechanisms. J Invest Dermatol (2007) 5.16

Impaired wound healing in mice with a disrupted plasminogen gene. Nat Med (1996) 4.72

Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol (2004) 4.16

Breaching the basement membrane: who, when and how? Trends Cell Biol (2008) 3.14

Interactions between extracellular matrix and growth factors in wound healing. Wound Repair Regen (2009) 2.83

Expression of matrix-metalloproteinases and their inhibitors in the wounds of diabetic and non-diabetic patients. Diabetologia (2002) 2.32

Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors. Wound Repair Regen (2000) 2.15

Wound repair in the context of extracellular matrix. Curr Opin Cell Biol (1994) 2.14

Regulation of matrix metalloproteinase activity in ischemic tissue by interleukin-10: role in ischemia-induced angiogenesis. Circ Res (2001) 1.78

Angiogenesis: vascular remodeling of the extracellular matrix involves metalloproteinases. Curr Opin Hematol (2003) 1.71

Functional overlap between two classes of matrix-degrading proteases in wound healing. EMBO J (1999) 1.69

Mechanism of action of PROMOGRAN, a protease modulating matrix, for the treatment of diabetic foot ulcers. Wound Repair Regen (2002) 1.68

Interleukin-1alpha and collagenase activity are elevated in chronic wounds. Plast Reconstr Surg (1998) 1.54

Ratios of activated matrix metalloproteinase-9 to tissue inhibitor of matrix metalloproteinase-1 in wound fluids are inversely correlated with healing of pressure ulcers. Wound Repair Regen (2002) 1.51

Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds. J Invest Dermatol (2000) 1.51

Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing. Wound Repair Regen (2002) 1.51

Identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases. Infect Immun (1992) 1.45

Monocyte chemoattractant protein-1 enhances gene expression and synthesis of matrix metalloproteinase-1 in human fibroblasts by an autocrine IL-1 alpha loop. J Immunol (2000) 1.43

The role of matrix metalloproteinases in wound healing. J Am Podiatr Med Assoc (2002) 1.41

Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds. Blood (2001) 1.39

Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healing. Diabet Med (2008) 1.38

Integration of the NF-kappaB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts. Cytokine (2000) 1.37

Interactions of cytokines, growth factors, and proteases in acute and chronic wounds. Wound Repair Regen (1996) 1.37

MMP-8 is the predominant collagenase in healing wounds and nonhealing ulcers. J Surg Res (1999) 1.37

Biochemical analysis of acute and chronic wound environments. Wound Repair Regen (2006) 1.32

Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids. J Invest Dermatol (1996) 1.31

The role of hyaluronic acid in wound healing: assessment of clinical evidence. Am J Clin Dermatol (2005) 1.29

The proteolytic environment of chronic wounds. Wound Repair Regen (2000) 1.29

Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors. Wound Repair Regen (2006) 1.27

A randomized, controlled trial of Promogran (a collagen/oxidized regenerated cellulose dressing) vs standard treatment in the management of diabetic foot ulcers. Arch Surg (2002) 1.21

Increased matrix metalloproteinase-9 (MMP-9) activity observed in chronic wound fluid is related to the clinical severity of the ulcer. Br J Dermatol (2008) 1.18

Bacterial protease inhibitors. Med Res Rev (2002) 1.10

Plasmin modulates vascular endothelial growth factor-A-mediated angiogenesis during wound repair. Am J Pathol (2006) 1.09

Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays. J Invest Dermatol (1992) 1.05

Fibronectin degradation in chronic wounds depends on the relative levels of elastase, alpha1-proteinase inhibitor, and alpha2-macroglobulin. J Invest Dermatol (1996) 1.04

Temporal expression of urokinase plasminogen activator, plasminogen activator inhibitor and gelatinase-B in chronic wound fluid switches from a chronic to acute wound profile with progression to healing. Wound Repair Regen (1999) 1.01

Proteases and the diabetic foot syndrome: mechanisms and therapeutic implications. Diabetes Care (2005) 0.98

Tumor necrosis factor bifunctionally regulates matrix metalloproteinases and tissue inhibitor of metalloproteinases (TIMP) production by human fibroblasts. FEBS Lett (1990) 0.96

Gelatinase activities in wounds of healing-impaired mice versus wounds of non-healing-impaired mice. J Burn Care Rehabil (2001) 0.95

Are bacterial proteases important virulence factors? J Periodontal Res (1997) 0.94

Advances in wound dressings. Clin Dermatol (2007) 0.94

Hyaluronic acid is a major component of the matrix of fetal rabbit skin and wounds: implications for healing by regeneration. Matrix (1991) 0.92

Proteinases, their inhibitors, and cytokine profiles in acute wound fluid. Wound Repair Regen (2000) 0.92

The role of endogenous and exogenous enzymes in chronic wounds: a focus on the implications of aberrant levels of both host and bacterial proteases in wound healing. Wound Repair Regen (2012) 0.90

Regulation of collagenase gene expression by IL-1 beta requires transcriptional and post-transcriptional mechanisms. Nucleic Acids Res (1994) 0.90

Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration. Int Wound J (2008) 0.89

Functionally modified gelatin microspheres impregnated collagen scaffold as novel wound dressing to attenuate the proteases and bacterial growth. Eur J Pharm Sci (2008) 0.85

Protease inhibitors protect growth factor activity in chronic wounds. Br J Dermatol (1997) 0.84

Protease inhibition by oleic acid transfer from chronic wound dressings to albumin. Int J Pharm (2007) 0.81

Wound fluids: a reflection of the state of healing. Ostomy Wound Manage (2000) 0.80

In vitro inhibition of human neutrophil elastase by oleic acid albumin formulations from derivatized cotton wound dressings. Int J Pharm (2004) 0.79

In vitro studies to show sequestration of matrix metalloproteinases by silver-containing wound care products. Ostomy Wound Manage (2007) 0.78

Articles by these authors

Silver and Alginates: Role in Wound Healing and Biofilm Control. Adv Wound Care (New Rochelle) (2015) 0.78

Biofilms and Wounds: An Overview of the Evidence. Adv Wound Care (New Rochelle) (2015) 0.77