Adenovirus-mediated transfer of VEGF into marrow stromal cells combined with PLGA/TCP scaffold increases vascularization and promotes bone repair in vivo.

PubWeight™: 0.81‹?›

🔗 View Article (PMC 3953961)

Published in Arch Med Sci on October 08, 2012

Authors

Chunguang Duan1, Jian Liu1, Zhi Yuan1, Guolin Meng1, Xiumei Yang2, Shuaijun Jia1, Jinkang Zhang1, Shi Chen1

Author Affiliations

1: Department of Orthopaedics and Traumatology, Xijing Hospital, Fourth Military Medical University, Xi'an, PR China.
2: Department of Ophthalmology, Xijing Hospital, Fourth Military Medical University, Xi'an, PR China.

Articles cited by this

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem (1998) 8.30

Bone marrow stromal stem cells: nature, biology, and potential applications. Stem Cells (2001) 6.86

Role of collagenous matrices in the adhesion and growth of cells. J Cell Biol (1981) 5.60

The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials (2000) 4.42

Self-regulation of growth in three dimensions. J Exp Med (1973) 2.87

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene (1999) 2.66

Effect of convection on osteoblastic cell growth and function in biodegradable polymer foam scaffolds. Biomaterials (2001) 1.94

Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects. J Bone Miner Res (2005) 1.57

Adult bone marrow stem/progenitor cells (MSCs) are preconditioned by microenvironmental "niches" in culture: a two-stage hypothesis for regulation of MSC fate. Sci STKE (2005) 1.54

The effect of platelet-rich plasma on healing in critical-size long-bone defects. Biomaterials (2008) 1.27

Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer. Circulation (1996) 1.26

Mechanism of bone metastasis: the role of osteoprotegerin and of the host-tissue microenvironment-related survival factors. Cancer Lett (2009) 1.22

Assessment of risks associated with cardiovascular gene therapy in human subjects. Circ Res (2001) 1.10

Impact of pore size on the vascularization and osseointegration of ceramic bone substitutes in vivo. J Biomed Mater Res A (2008) 1.08

In vitro biocompatibility assessment of naturally derived and synthetic biomaterials using normal human urothelial cells. J Biomed Mater Res (2001) 1.04

Biomaterials in orthopaedic surgery: effects of different hydroxyapatites and demineralized bone matrix on proliferation rate and bone matrix synthesis by human osteoblasts. Biomaterials (1995) 0.99

Bone tissue engineering evaluation based on rat calvaria stromal cells cultured on modified PLGA scaffolds. Biomaterials (2005) 0.94

Endothelium-dependent relaxation of collateral microvessels after intramuscular gene transfer of vascular endothelial growth factor in a rat model of hindlimb ischemia. Circulation (1998) 0.92

Skeletal repair in rabbits using a novel biomimetic composite based on adipose-derived stem cells encapsulated in collagen I gel with PLGA-beta-TCP scaffold. J Orthop Res (2010) 0.91

Therapeutic implications of osteoprotegerin. Cancer Cell Int (2009) 0.89

Collagen I gel can facilitate homogenous bone formation of adipose-derived stem cells in PLGA-beta-TCP scaffold. Cells Tissues Organs (2007) 0.88

Bioabsorbable materials for guided bone regeneration prior to implant placement and 7-year follow-up: report of 14 cases. J Periodontol (2001) 0.86

Evaluation of guided bone regeneration in rabbit femur using collagen membranes. Implant Dent (2000) 0.85

Cell-cell interaction promotes rat marrow stromal cell differentiation into endothelial cell via activation of TACE/TNF-alpha signaling. Cell Transplant (2009) 0.84

Effects of clodronate combined with hydroxyapatite on multi-directional differentiation of mesenchymal stromal cells. Arch Med Sci (2010) 0.84

Osteogenetic properties of reimplanted decalcified and undecalcified autologous bone in the rabbit radius. Scand J Plast Reconstr Surg (1982) 0.79

Short and long-term effects of hVEGF-A(165) in Cre-activated transgenic mice. PLoS One (2006) 0.79