Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.

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Published in Cell Metab on April 01, 2014

Authors

Prashant Mishra1, Valerio Carelli2, Giovanni Manfredi3, David C Chan4

Author Affiliations

1: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
2: IRCCS Istituto delle Scienze Neurologiche di Bologna, Department of Biomedical and NeuroMotor Sciences, University of Bologna, Via Ugo Foscolo 7, 40123 Bologna, Italy.
3: Departments of Neurology and Neuroscience, Weill Medical College of Cornell University, 1300 York Avenue, A501, New York, NY 10065, USA.
4: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: dchan@caltech.edu.

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