Structural characterization of P1'-diversified urea-based inhibitors of glutamate carboxypeptidase II.

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🔗 View Article (PMC 4077459)

Published in Bioorg Med Chem Lett on March 28, 2014

Authors

Jiri Pavlicek1, Jakub Ptacek1, Jiri Cerny1, Youngjoo Byun2, Lubica Skultetyova1, Martin G Pomper3, Jacek Lubkowski4, Cyril Barinka5

Author Affiliations

1: Institute of Biotechnology, Academy of Sciences of the Czech Republic, v.v.i., Laboratory of Structural Biology, Vídeňská 1083, 14220 Prague 4, Czech Republic.
2: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 1550 Orleans Street, Baltimore, MD 21231, USA; College of Pharmacy, Korea University, 2511 Sejong-ro, Sejong 339-700, South Korea.
3: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, 1550 Orleans Street, Baltimore, MD 21231, USA.
4: Center for Cancer Research, Frederick National Laboratory for Cancer Research, Macromolecular Crystallography Laboratory, Frederick, MD 21702, USA.
5: Institute of Biotechnology, Academy of Sciences of the Czech Republic, v.v.i., Laboratory of Structural Biology, Vídeňská 1083, 14220 Prague 4, Czech Republic. Electronic address: cyril.barinka@img.cas.cz.

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