Published in J Physiol on September 01, 1988
Ca2+ current-driven nonlinear amplification by the mammalian cochlea in vitro. Nat Neurosci (2005) 3.00
The micromachinery of mechanotransduction in hair cells. Annu Rev Neurosci (2007) 2.17
Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels. J Gen Physiol (2000) 2.09
Rapid adaptation of single mechanosensitive channels in Xenopus oocytes. Proc Natl Acad Sci U S A (1992) 1.73
Probing the pore of the auditory hair cell mechanotransducer channel in turtle. J Physiol (2004) 1.71
Cytoplasmic and intra-nuclear binding of gentamicin does not require endocytosis. Hear Res (2005) 1.37
Control of intracellular calcium by ATP in isolated outer hair cells of the guinea-pig cochlea. J Physiol (1990) 1.34
Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing. J Physiol (2004) 1.32
Amiloride block of the mechanosensitive cation channel in Xenopus oocytes. J Physiol (1991) 1.29
The physiology of mechanoelectrical transduction channels in hearing. Physiol Rev (2014) 1.23
Block by amiloride and its derivatives of mechano-electrical transduction in outer hair cells of mouse cochlear cultures. J Physiol (1994) 1.17
Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line. Hear Res (2009) 1.13
What is the hair cell transduction channel? J Physiol (2006) 1.08
Mechano-electrical transduction: new insights into old ideas. J Membr Biol (2006) 1.07
Defining features of the hair cell mechanoelectrical transducer channel. Pflugers Arch (2009) 1.05
Spikes and membrane potential oscillations in hair cells generate periodic afferent activity in the frog sacculus. J Neurosci (2009) 1.05
Muscarinic agonists and ATP increase the intracellular Ca2+ concentration in chick cochlear hair cells. J Physiol (1990) 1.04
Evidence of a Hopf bifurcation in frog hair cells. Biophys J (2001) 1.01
Pharmacology of stretch-activated K channels in Lymnaea neurones. Br J Pharmacol (1995) 0.97
Mechanism of spontaneous activity in afferent neurons of the zebrafish lateral-line organ. J Neurosci (2011) 0.97
Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin. Hear Res (2012) 0.96
Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes. Br J Pharmacol (1992) 0.95
Subconductance block of single mechanosensitive ion channels in skeletal muscle fibers by aminoglycoside antibiotics. J Gen Physiol (1996) 0.91
Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Adv Genet (2011) 0.88
P2X antagonists inhibit styryl dye entry into hair cells. Neuroscience (2009) 0.88
Ionic effects on amiloride block of the mechanosensitive channel in Xenopus oocytes. Br J Pharmacol (1993) 0.88
Permeation properties of the hair cell mechanotransducer channel provide insight into its molecular structure. J Neurophysiol (2012) 0.87
Using injectoporation to deliver genes to mechanosensory hair cells. Nat Protoc (2014) 0.86
Inhibitory effect of amiloride and gadolinium on fine afferent nerves in the rat knee: evidence of mechanogated ion channels in joints. Exp Brain Res (2005) 0.83
A hydrodynamic sensory antenna used by killifish for nocturnal hunting. J Exp Biol (2011) 0.79
The effect of amiloride on the resting potential and the electrical constants of frog skeletal muscle fibres. J Physiol (1991) 0.78
Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity. Front Cell Neurosci (2016) 0.75
The Epithelial Sodium Channel and the Processes of Wound Healing. Biomed Res Int (2016) 0.75
The effects of ototoxic drugs on mechano-electric transduction channels in chick cochlear hair cells. Eur Arch Otorhinolaryngol (1994) 0.75
Ionic blockage of sodium channels in nerve. J Gen Physiol (1973) 20.47
Negative conductance caused by entry of sodium and cesium ions into the potassium channels of squid axons. J Gen Physiol (1972) 10.92
Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli. Proc Natl Acad Sci U S A (1977) 5.14
Studies of calcium channels in rat clonal pituitary cells with patch electrode voltage clamp. J Physiol (1982) 4.81
Ionic basis of the receptor potential in a vertebrate hair cell. Nature (1979) 4.22
Amiloride: a molecular probe of sodium transport in tissues and cells. Am J Physiol (1982) 3.49
Voltage- and ion-dependent conductances in solitary vertebrate hair cells. Nature (1983) 3.44
Mechano-electrical transduction currents in isolated vestibular hair cells of the chick. J Physiol (1985) 3.25
Variation of membrane properties in hair cells isolated from the turtle cochlea. J Physiol (1987) 3.00
Extracellular current flow and the site of transduction by vertebrate hair cells. J Neurosci (1982) 2.82
Studies of ionic currents in the isolated vestibular hair cell of the chick. J Physiol (1984) 2.21
Formation, circulation and chemical properties of the labyrinthine fluids. Br Med Bull (1956) 1.98
Sodium-specific membrane channels of frog skin are pores: current fluctuations reveal high turnover. Science (1977) 1.85
Voltage-dependent block by amiloride and other monovalent cations of apical Na channels in the toad urinary bladder. J Membr Biol (1984) 1.45
Mechanical stimulation and Fura-2 fluorescence in the hair bundle of dissociated hair cells of the chick. J Physiol (1988) 1.43
Single-channel recordings from amiloride-sensitive epithelial sodium channel. Am J Physiol (1985) 1.40
Gating properties of the mechano-electrical transducer channel in the dissociated vestibular hair cell of the chick. J Physiol (1987) 1.14
Ion selectivity of the apical membrane Na channel in the toad urinary bladder. J Membr Biol (1982) 1.13
The amiloride-sensitive sodium channel. Am J Physiol (1986) 1.10
Voltage dependence of Na channel blockage by amiloride: relaxation effects in admittance spectra. J Membr Biol (1985) 1.06
Apical sodium entry in split frog skin: current-voltage relationship. J Membr Biol (1984) 0.90
Detection of 5-methylcytosine in DNA sequences. Nucleic Acids Res (1978) 7.03
The Y-family of DNA polymerases. Mol Cell (2001) 6.49
Origin of replication of colicin E1 plasmid DNA. Proc Natl Acad Sci U S A (1977) 5.38
Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature (1996) 5.25
Identification of additional genes belonging to the LexA regulon in Escherichia coli. Mol Microbiol (2000) 5.08
Studies of calcium channels in rat clonal pituitary cells with patch electrode voltage clamp. J Physiol (1982) 4.81
Inactivation kinetics and steady-state current noise in the anomalous rectifier of tunicate egg cell membranes. J Physiol (1978) 3.62
Multiple pathways for SOS-induced mutagenesis in Escherichia coli: an overexpression of dinB/dinP results in strongly enhancing mutagenesis in the absence of any exogenous treatment to damage DNA. Proc Natl Acad Sci U S A (1997) 3.53
Surface potential reflected in both gating and permeation mechanisms of sodium and calcium channels of the tunicate egg cell membrane. J Physiol (1977) 3.33
Mechano-electrical transduction currents in isolated vestibular hair cells of the chick. J Physiol (1985) 3.25
DNA gyrase and DNA supercoiling. Cold Spring Harb Symp Quant Biol (1979) 3.16
Site-specific interaction of DNA gyrase with DNA. Proc Natl Acad Sci U S A (1981) 2.75
Nucleotide sequence and gene organization of ColE1 DNA. J Biol Chem (1985) 2.45
Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa. Genes Dev (2000) 2.38
Molecular characterization of the hyperpolarization-activated cation channel in rabbit heart sinoatrial node. J Biol Chem (1999) 2.23
Studies of ionic currents in the isolated vestibular hair cell of the chick. J Physiol (1984) 2.21
Studies of single calcium channel currents in rat clonal pituitary cells. J Physiol (1983) 2.16
Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem (2001) 2.15
Potassium rectifications of the starfish oocyte membrane and their changes during oocyte maturation. J Physiol (1975) 2.14
Structural analysis of the dnaA and dnaN genes of Escherichia coli. Gene (1984) 2.11
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene. J Biol Chem (2000) 2.06
Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells. Science (1996) 1.80
Mutation enhancement by DINB1, a mammalian homologue of the Escherichia coli mutagenesis protein dinB. Genes Cells (1999) 1.79
Nucleotide-sequence analysis of Tn3 (ap): implications for insertion and deletion. Cold Spring Harb Symp Quant Biol (1979) 1.78
Nucleotide sequence of the region required for maintenance of colicin E1 plasmid. Mol Gen Genet (1979) 1.69
Molecular cloning of a novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors. J Biol Chem (1997) 1.65
Single K+ channel currents of anomalous rectification in cultured rat myotubes. Proc Natl Acad Sci U S A (1981) 1.64
Resection of the caudate lobe of the liver for primary and recurrent hepatocellular carcinomas. J Am Coll Surg (1997) 1.51
Sed1p is a major cell wall protein of Saccharomyces cerevisiae in the stationary phase and is involved in lytic enzyme resistance. J Bacteriol (1998) 1.50
The role of GABAergic inputs for coincidence detection in the neurones of nucleus laminaris of the chick. J Physiol (1998) 1.42
Action potential and non-linear current-voltage relation in starfish oocytes. J Physiol (1975) 1.40
A sandwich cup method for the penetration assay of antimicrobial agents through Pseudomonas exopolysaccharides. Microbiol Immunol (1994) 1.40
Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen. Cancer Res (1999) 1.38
Xanthine oxidase-induced histamine release from isolated rat peritoneal mast cells: involvement of hydrogen peroxide. Biochem Pharmacol (1979) 1.37
Control of intracellular calcium by ATP in isolated outer hair cells of the guinea-pig cochlea. J Physiol (1990) 1.34
Translesion DNA synthesis catalyzed by human pol eta and pol kappa across 1,N6-ethenodeoxyadenosine. J Biol Chem (2001) 1.34
Inhibition of Escherichia coli RecA coprotease activities by DinI. EMBO J (1998) 1.32
Postnatal development of phase-locked high-fidelity synaptic transmission in the medial nucleus of the trapezoid body of the rat. J Neurosci (1998) 1.25
Unitary current through sodium channel and anomalous rectifier channel estimated from transient current noise in the tunicate egg. J Physiol (1981) 1.24
Delta pH-dependent accumulation of tetracycline in Escherichia coli. Antimicrob Agents Chemother (1991) 1.22
Acetylcholine dose-response relation and the effect of cesium ions in the rat adrenal chromaffin cell under voltage clamp. Pflugers Arch (1987) 1.21
Development of neuromuscular transmission in a larval tunicate. J Physiol (1977) 1.20
Requirement of the Escherichia coli dnaA gene function for ori-2-dependent mini-F plasmid replication. J Bacteriol (1987) 1.17
DNA gyrase: site-specific interactions and transient double-strand breakage of DNA. Cold Spring Harb Symp Quant Biol (1981) 1.16
DNA transfection of mouse lymphoid cells by the combination of DEAE-dextran-mediated DNA uptake and osmotic shock procedure. Biochim Biophys Acta (1990) 1.15
Mechanoelectrical transducer has discrete conductances in the chick vestibular hair cell. Proc Natl Acad Sci U S A (1984) 1.14
Synthesis and structure--activity analysis of novel dihydropyridine derivatives to overcome multidrug resistance. Bioorg Med Chem Lett (2001) 1.12
Multicopy suppressors of the cold-sensitive phenotype of the pcsA68 (dinD68) mutation in Escherichia coli. J Bacteriol (1996) 1.09
DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer. Cancer Res (2001) 1.09
Prognostic factors after hepatic resection for hepatocellular carcinoma associated with Child-Turcotte class B and C cirrhosis. Ann Surg (1999) 1.09
Rearrangement of lambda light chain genes in mature B cells in vitro and in vivo. Function of reexpressed recombination-activating gene (RAG) products. J Exp Med (1998) 1.07
Characterization of B cells expressing recombination activating genes in germinal centers of immunized mouse lymph nodes. J Immunol (1997) 1.06
Expression of human and mouse genes encoding polkappa: testis-specific developmental regulation and AhR-dependent inducible transcription. Genes Cells (2001) 1.05
A novel type of E. coli mutants with increased chromosomal copy number. Mol Gen Genet (1983) 1.05
Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer. Oncol Rep (2000) 1.05
Physical interactions between DinI and RecA nucleoprotein filament for the regulation of SOS mutagenesis. EMBO J (2001) 1.04
Muscarinic agonists and ATP increase the intracellular Ca2+ concentration in chick cochlear hair cells. J Physiol (1990) 1.04
Exercise training improves ageing-induced decrease in eNOS expression of the aorta. Acta Physiol Scand (2003) 1.04
Expression of recombination activating genes in germinal center B cells: involvement of interleukin 7 (IL-7) and the IL-7 receptor. J Exp Med (1998) 1.02
Expression of vascular endothelial growth factor in patients with testicular germ cell tumors as an indicator of metastatic disease. Cancer (1999) 1.02
Intravesical adriamycin chemotherapy in bladder cancer. Cancer Chemother Pharmacol (1983) 1.02
Genomic structures and chromosomal location of p91, a novel murine regulatory receptor family. J Biochem (1998) 1.01
CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver. Gut (2009) 1.01
Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV. Biochemistry (2001) 1.01
Intravesical chemotherapy with 4'-epi-Adriamycin in patients with superficial bladder tumors. Cancer Chemother Pharmacol (1986) 1.00
Glucose uptake by individual skeletal muscles during running using whole-body positron emission tomography. Eur J Appl Physiol (2000) 1.00
Expansion of methylmercury poisoning outside of Minamata: an epidemiological study on chronic methylmercury poisoning outside of Minamata. Environ Res (1995) 0.99
Mechanism of augmentation of the antibody response in vitro by 2-mercaptoethanol in murine lymphocytes. I. 2-Mercaptoethanol-induced stimulation of the uptake of cystine, an essential amino acid. J Exp Med (1982) 0.99
Isolation and properties of beta-lactamase-less mutants from clinically important gram-negative bacteria. J Antibiot (Tokyo) (1977) 0.98
Reg IV enhances peritoneal metastasis in gastric carcinomas. Cell Prolif (2009) 0.98
Muscarinic receptor hyperpolarizes cochlear hair cells of chick by activating Ca(2+)-activated K+ channels. J Physiol (1991) 0.98
Synchronisation of neurotransmitter release during postnatal development in a calyceal presynaptic terminal of rat. J Physiol (2001) 0.98
The effect of caged calcium release on the adaptation of the transduction current in chick hair cells. J Physiol (1992) 0.98
Determinants of activation kinetics in mammalian hyperpolarization-activated cation channels. J Physiol (2001) 0.96
Voltage-gated ionic currents and their roles in timing coding in auditory neurons of the nucleus magnocellularis of the chick. Neurosci Res (1996) 0.95
Mutagenic and nonmutagenic bypass of DNA lesions by Drosophila DNA polymerases dpoleta and dpoliota. J Biol Chem (2001) 0.94
Comparison of the effects of glucagon-like peptide-1-(1-37) and -(7-37) and glucagon on islet hormone release from isolated perfused canine and rat pancreases. Endocrinology (1989) 0.93
Acetylcholine increases intracellular Ca2+ concentration and hyperpolarizes the guinea-pig outer hair cell. Hear Res (1993) 0.93
Nucleotide sequence of the Escherichia coli solA gene encoding a sarcosine oxidase-like protein and characterization of its product. Gene (1996) 0.93
Voltage-gated and synaptic currents in rat Purkinje cells in dissociated cell cultures. Proc Natl Acad Sci U S A (1986) 0.92
Release of Ca2+ is the crucial step for the potentiation of IPSCs in the cultured cerebellar Purkinje cells of the rat. J Physiol (1996) 0.92
Prostaglandin I2 as a potentiator of acute inflammation in rats. Prostaglandins (1978) 0.92
Synaptic responses to mechanical stimulation in calyceal and bouton type vestibular afferents studied in an isolated preparation of semicircular canal ampullae of chicken. Exp Brain Res (1990) 0.92
Activation of glutamate receptors in response to membrane depolarization of hair cells isolated from chick cochlea. J Physiol (1994) 0.91
Nuclear accumulation of p53 in normal human fibroblasts is induced by various cellular stresses which evoke the heat shock response, independently of the cell cycle. Jpn J Cancer Res (1995) 0.91
The Escherichia coli ldcC gene encodes another lysine decarboxylase, probably a constitutive enzyme. Genes Genet Syst (1997) 0.89
Scavenging effect of N-acetyl-L-cysteine against reactive oxygen species in human semen: a possible therapeutic modality for male factor infertility? Andrologia (1997) 0.89
Receptor for advanced glycation end products (RAGE) is important in the prediction of recurrence in human oral squamous cell carcinoma. Histopathology (2007) 0.89
X-linked Alport syndrome with normal distribution of collagen IV alpha chains in epidermal basement membrane. Contrib Nephrol (1997) 0.89
Lateral and medial olivocochlear neurons have distinct electrophysiological properties in the rat brain slice. J Neurophysiol (1997) 0.89
[Intravesical chemotherapy of adriamycin and verapamil in patients with recurrent superficial bladder cancer: preliminary report]. Gan To Kagaku Ryoho (1987) 0.89
Voltage-gated and chemically gated ionic channels in the cultured cochlear ganglion neurone of the chick. J Physiol (1990) 0.88
Primary adenocarcinoma of the renal pelvis. Report of two cases and brief review of literature. Acta Pathol Jpn (1983) 0.88
Sp1 protein contributes to airway-specific rat MUC 2 mucin gene transcription. Gene (1997) 0.88
[Comparative studies of DL-8280 and pipemidic acid in complicated urinary tract infections by double-blind method]. Hinyokika Kiyo (1984) 0.87
Reversal of expression of 15-lipoxygenase-1 to cyclooxygenase-2 is associated with development of colonic cancer. Histopathology (2007) 0.87
[The pathogenesis of chronic subdural hematoma--sequential study with computerized tomography (author's transl)]. Neurol Med Chir (Tokyo) (1980) 0.87
Factors involved in beta-lactam antibiotic resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother (1977) 0.86
The role of inositol trisphosphate on ACh-induced outward currents in bullfrog saccular hair cells. Brain Res (1994) 0.85
Dihydrostreptomycin modifies adaptation and blocks the mechano-electric transducer in chick cochlear hair cells. Brain Res (1993) 0.85