Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis.

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🔗 View Article (PMC 4016197)

Published in Cancer Cell on April 14, 2014

Authors

Weiying Zhou1, Miranda Y Fong2, Yongfen Min3, George Somlo4, Liang Liu5, Melanie R Palomares6, Yang Yu5, Amy Chow2, Sean Timothy Francis O'Connor2, Andrew R Chin7, Yun Yen8, Yafan Wang9, Eric G Marcusson10, Peiguo Chu11, Jun Wu12, Xiwei Wu13, Arthur Xuejun Li14, Zhuo Li15, Hanlin Gao16, Xiubao Ren17, Mark P Boldin18, Pengnian Charles Lin3, Shizhen Emily Wang19

Author Affiliations

1: Department of Cancer Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA; Department of Pharmacology, College of Pharmacy, The Third Military Medical University, Chongqing, 400038, China.
2: Department of Cancer Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
3: Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.
4: Department of Medical Oncology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
5: Department of Cancer Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA; Department of Biotherapy and Key Laboratory of Cancer Immunology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China.
6: Department of Medical Oncology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA; Department of Population Sciences, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
7: Department of Cancer Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA; City of Hope Irell & Manella Graduate School of Biological Sciences, Duarte, CA 91010, USA.
8: Department of Molecular Pharmacology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA; Core of Translational Research Laboratory, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
9: Core of Translational Research Laboratory, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
10: Oncology and Basic Mechanisms, Regulus Therapeutics, San Diego, CA 92121, USA.
11: Department of Pathology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
12: Department of Comparative Medicine, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
13: Core of Integrative Genomics, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
14: Department of Information Science, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
15: Core of Electron Microscopy, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
16: Department of Cancer Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA; Core of Integrative Genomics, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
17: Department of Biotherapy and Key Laboratory of Cancer Immunology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China.
18: Department of Molecular and Cellular Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA.
19: Department of Cancer Biology, City of Hope Beckman Research Institute and Medical Center, Duarte, CA 91010, USA. Electronic address: ewang@coh.org.

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