Published in Eur J Immunol on August 01, 1989
Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci U S A (1992) 6.37
Activation of human dendritic cells through CD40 cross-linking. J Exp Med (1994) 6.16
CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha. J Exp Med (1996) 3.82
Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med (1992) 3.40
CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40. J Exp Med (1993) 3.11
Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J Exp Med (1991) 3.04
Identification of functional human splenic memory B cells by expression of CD148 and CD27. J Exp Med (1998) 3.01
Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion. J Exp Med (1992) 2.86
In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. J Exp Med (1993) 2.72
Measles virus infects human dendritic cells and blocks their allostimulatory properties for CD4+ T cells. J Exp Med (1997) 2.21
Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10. J Exp Med (1993) 2.00
Clonal dissection of the human memory B-cell repertoire following infection and vaccination. Eur J Immunol (2009) 1.74
Human thymus contains IFN-alpha-producing CD11c(-), myeloid CD11c(+), and mature interdigitating dendritic cells. J Clin Invest (2001) 1.61
Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction. J Exp Med (1994) 1.61
The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future. J Autoimmun (2007) 1.55
Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes. J Exp Med (1993) 1.42
The 26-kD transmembrane form of tumor necrosis factor alpha on activated CD4+ T cell clones provides a costimulatory signal for human B cell activation. J Exp Med (1993) 1.41
CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype. J Exp Med (1996) 1.35
Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J Exp Med (1996) 1.35
Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes. J Exp Med (1996) 1.32
Human B cell precursors proliferate and express CD23 after CD40 ligation. J Exp Med (1993) 1.18
Interleukin 10 induces B lymphocytes from IgA-deficient patients to secrete IgA. J Clin Invest (1994) 1.16
The ability of synoviocytes to support terminal differentiation of activated B cells may explain plasma cell accumulation in rheumatoid synovium. J Clin Invest (1995) 1.14
Localization in situ of costimulatory molecules and cytokines in B-cell non-Hodgkin's lymphoma. Immunology (1998) 1.06
CD40 antigen is expressed by endothelial cells and tumor cells in Kaposi's sarcoma. Am J Pathol (1996) 1.03
Functional activity of CD40 antibodies correlates to the position of binding relative to CD154. Immunology (2001) 1.00
IL-4 induces neutrophilic maturation of HL-60 cells and activation of human peripheral blood neutrophils. Clin Exp Immunol (1995) 0.97
Mononuclear cell subpopulations in preterm and full-term neonates: independent effects of gestational age, neonatal infection, maternal pre-eclampsia, maternal betamethason therapy, and mode of delivery. Clin Exp Immunol (1999) 0.95
Negative selection of human germinal center B cells by prolonged BCR cross-linking. J Exp Med (1996) 0.95
CD40 plays an essential role in the activation of human B cells by murine EL4B5 cells. Immunology (1993) 0.94
CD40 expression in Hodgkin's disease. Am J Pathol (1994) 0.94
Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB. Invest Ophthalmol Vis Sci (2012) 0.94
Potential role of soluble CD40 in the humoral immune response impairment of uraemic patients. Immunology (2003) 0.92
Exploiting human memory B cell heterogeneity for improved vaccine efficacy. Front Immunol (2011) 0.85
Antibodies to distinct epitopes on the CD40 molecule co-operate in stimulation and can be used for the detection of soluble CD40. Immunology (1994) 0.84
Costimulatory molecules as immunotherapeutic targets in systemic lupus erythematosus. Springer Semin Immunopathol (2006) 0.82
Differential requirements for induction of total immunoglobulin and physiological rheumatoid factor production by human peripheral blood B cells. Clin Exp Immunol (2001) 0.79
CD40 antibodies defining distinct epitopes display qualitative differences in their induction of B-cell differentiation. Immunology (1996) 0.79
Surface expression and release of soluble forms of CD8 and CD23 in CD40- and IL-4-activated mononuclear cells from patients with Graves' disease (GD). Clin Exp Immunol (1998) 0.79
Inhibition of IL-4 receptor up-regulation on B cells by antisense oligodeoxynucleotide suppresses IL-4-induced human IgE production. Clin Exp Immunol (1995) 0.78
Locomotor properties of human germinal centre B cells: activation by anti-CD40 and IL-4 allows chemoattraction by anti-immunoglobulin. Immunology (1997) 0.77
IL-13 has only a subset of IL-4-like activities on B chronic lymphocytic leukaemia cells. Immunology (1994) 0.77
Co-culture of the 55-6 B cell hybridoma with the EL-4 thymoma cell. Effect on cell growth and monoclonal antibody production. Cytotechnology (2013) 0.76
Immune activation during the implantation phase causes preeclampsia-like symptoms via the CD40-CD40 ligand pathway in pregnant mice. Hypertens Res (2016) 0.75
Generation of Human B-Cell Lines Dependent on CD40-Ligation and Interleukin-4. Front Immunol (2015) 0.75
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med (1996) 8.59
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science (2001) 8.14
GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells. Nature (1992) 7.41
Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci U S A (1992) 6.37
CD40-CD40 ligand. J Leukoc Biol (2000) 6.28
Activation of human dendritic cells through CD40 cross-linking. J Exp Med (1994) 6.16
The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. J Exp Med (1997) 5.23
IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. Proc Natl Acad Sci U S A (1988) 5.03
Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities. Proc Natl Acad Sci U S A (1986) 4.59
Analysis of somatic mutation in five B cell subsets of human tonsil. J Exp Med (1994) 4.52
Epstein-Barr virus (EBV) induces expression of B-cell activation markers on in vitro infection of EBV-negative B-lymphoma cells. Proc Natl Acad Sci U S A (1987) 3.98
CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha. J Exp Med (1996) 3.82
IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol (1988) 3.47
Generation of memory B cells and plasma cells in vitro. Science (1995) 3.45
Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A. J Exp Med (1992) 3.40
IL-6 switches the differentiation of monocytes from dendritic cells to macrophages. Nat Immunol (2000) 3.39
Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes. J Exp Med (1987) 3.22
Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J Exp Med (1991) 3.04
Sensing pathogens and tuning immune responses. Science (2001) 2.73
Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J Immunol (2001) 2.64
Functions of CD40 on B cells, dendritic cells and other cells. Curr Opin Immunol (1997) 2.62
Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23. J Virol (1990) 2.58
Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2. Immunity (1995) 2.57
A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment. Immunity (1998) 2.56
In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med (1999) 2.54
Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3. J Exp Med (1994) 2.50
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes. J Exp Med (1998) 2.39
B cell growth-promoting activity of recombinant human interleukin 4. J Immunol (1987) 2.31
Interleukin-17. Int Rev Immunol (1998) 2.31
The cytokine profile expressed by human dendritic cells is dependent on cell subtype and mode of activation. J Immunol (1998) 2.27
Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice. Cancer Res (1999) 2.23
Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation. Immunity (1996) 2.22
Measles virus infects human dendritic cells and blocks their allostimulatory properties for CD4+ T cells. J Exp Med (1997) 2.21
Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J Exp Med (1995) 2.19
IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. J Immunol (1988) 2.16
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J Exp Med (1994) 2.14
Dendritic cells enhance growth and differentiation of CD40-activated B lymphocytes. J Exp Med (1997) 2.14
Recombinant interleukin 4 promotes the growth of human T cells. J Immunol (1987) 2.13
Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J Immunol (2001) 2.10
Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10. J Exp Med (1993) 2.00
Production and characterization of a monoclonal antibody specific for the human lymphocyte low affinity receptor for IgE: CD 23 is a low affinity receptor for IgE. J Immunol (1987) 1.99
Interferon gamma inhibits interleukin 10 production by monocytes. J Exp Med (1993) 1.96
The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface. Eur J Immunol (1999) 1.93
Flt3-ligand and granulocyte colony-stimulating factor mobilize distinct human dendritic cell subsets in vivo. J Immunol (2000) 1.93
Dendritic cells capable of stimulating T cells in germinal centres. Nature (1996) 1.90
Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells. J Exp Med (2001) 1.85
Molecular biology of interleukin 4 and interleukin 5 genes and biology of their products that stimulate B cells, T cells and hemopoietic cells. Immunol Rev (1988) 1.84
Granulocyte-macrophage colony-stimulating factor synergizes with interleukin-6 in supporting the proliferation of human myeloma cells. Blood (1990) 1.75
CD40-CD40 ligand: a multifunctional receptor-ligand pair. Adv Immunol (1996) 1.70
Human dendritic cells skew isotype switching of CD40-activated naive B cells towards IgA1 and IgA2. J Exp Med (1997) 1.69
Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol (1995) 1.69
Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma. J Immunol (1988) 1.67
Modulating the immune response with dendritic cells and their growth factors. Trends Immunol (2001) 1.66
Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10. J Immunol (1995) 1.63
Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells. J Exp Med (2000) 1.62
Interleukin-4 and interleukin-13: their similarities and discrepancies. Int Rev Immunol (1998) 1.60
Memory B cells are biased towards terminal differentiation: a strategy that may prevent repertoire freezing. J Exp Med (1997) 1.59
Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes. J Exp Med (2000) 1.59
B-chronic lymphocytic leukemias can undergo isotype switching in vivo and can be induced to differentiate and switch in vitro. Blood (1996) 1.57
Normal human IgD+IgM- germinal center B cells can express up to 80 mutations in the variable region of their IgD transcripts. Immunity (1996) 1.56
Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2. J Exp Med (1996) 1.55
Epstein-Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival. EMBO J (1996) 1.53
Dendritic cells: On the move from bench to bedside. Nat Med (2001) 1.52
Serum interleukin-10 in non-Hodgkin's lymphoma: a prognostic factor. Blood (1993) 1.52
Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes. J Immunol (1998) 1.52
Dendritic cells. Adv Immunol (1999) 1.51
Low levels of interleukin-4 and high levels of transforming growth factor beta in rheumatoid synovitis. Arthritis Rheum (1990) 1.51
Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studies. J Immunol (2001) 1.49
Interleukin-17 activates human renal epithelial cells in vitro and is expressed during renal allograft rejection. J Am Soc Nephrol (1998) 1.47
The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor. J Immunol (1997) 1.46
Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM. J Immunol (1988) 1.44
CD40 ligation counteracts Fas-induced apoptosis of human dendritic cells. Int Immunol (1997) 1.44
Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid synovitis. Arthritis Rheum (1992) 1.43
Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes. J Exp Med (1993) 1.42
B cells regulate expression of CD40 ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40. Eur J Immunol (1994) 1.41
High levels of circulating IL-10 in human malaria. Clin Exp Immunol (1994) 1.41
CD40 ligation on human cord blood CD34+ hematopoietic progenitors induces their proliferation and differentiation into functional dendritic cells. J Exp Med (1997) 1.38
Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells. J Exp Med (1998) 1.36
Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2. J Exp Med (1988) 1.36
The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor. J Biol Chem (1995) 1.35
CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype. J Exp Med (1996) 1.35
Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J Exp Med (1996) 1.35
Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses. J Immunol (2000) 1.33
Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells. Int Immunol (1994) 1.32
Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes. J Exp Med (1996) 1.32
Dendritic cells and immunity against cancer. J Intern Med (2011) 1.32
Dendritic cells: a link between innate and adaptive immunity. J Clin Immunol (1999) 1.31
Human interferon-gamma acts as a B cell growth factor in the anti-IgM antibody co-stimulatory assay but has no direct B cell differentiation activity. J Immunol (1986) 1.30
The normal counterpart of IgD myeloma cells in germinal center displays extensively mutated IgVH gene, Cmu-Cdelta switch, and lambda light chain expression. J Exp Med (1998) 1.30
The low-affinity receptor for IgE (CD23) on B lymphocytes is spatially associated with HLA-DR antigens. J Exp Med (1988) 1.29
Epitope mapping of recombinant human gamma interferon using monoclonal antibodies. Mol Immunol (1989) 1.27
Dendritic cells directly modulate B cell growth and differentiation. J Leukoc Biol (1999) 1.26