Published in Adv Synth Catal on January 13, 2014
NiXantphos: a deprotonatable ligand for room-temperature palladium-catalyzed cross-couplings of aryl chlorides. J Am Chem Soc (2014) 1.16
Room-temperature palladium-catalyzed direct 2-arylation of benzoxazoles with aryl and heteroaryl bromides. Chem Commun (Camb) (2014) 0.87
Reversed-Polarity Synthesis of Diaryl Ketones through Palladium-Catalyzed Direct Arylation of 2-Aryl-1,3-dithianes. Adv Synth Catal (2014) 0.83
Chemoselective Palladium-Catalyzed Deprotonative Arylation/[1,2]-Wittig Rearrangement of Pyridylmethyl Ethers. Chem Sci (2015) 0.82
Synthesis of (diarylmethyl)amines using Ni-catalyzed arylation of C(sp(3))-H bonds. Chem Sci (2015) 0.82
Palladium-Catalyzed Benzylic C-H Arylation of Azaarylmethylamines. Org Lett (2015) 0.79
Palladium-catalyzed α-arylation of aryl acetic acid derivatives via dienolate intermediates with aryl chlorides and bromides. Org Lett (2015) 0.79
Palladium-Catalyzed Benzylic Arylation of Pyridylmethyl Silyl Ethers: One-Pot Synthesis of Aryl(pyridyl)methanols. Org Lett (2016) 0.77
Palladium-Catalyzed α-Arylation of Methyl Sulfonamides with Aryl Chlorides. Adv Synth Catal (2016) 0.75
Tandem C(sp(3))-H Arylation/Oxidation and Arylation/Allylic Substitution of Isoindolinones. Adv Synth Catal (2016) 0.75
Palladium-catalyzed ligand-directed C-H functionalization reactions. Chem Rev (2010) 5.92
Palladium(II)-catalyzed C-H activation/C-C cross-coupling reactions: versatility and practicality. Angew Chem Int Ed Engl (2009) 5.09
Palladium-catalyzed coupling reactions of aryl chlorides. Angew Chem Int Ed Engl (2002) 3.51
Palladium- and copper-catalyzed arylation of carbon-hydrogen bonds. Acc Chem Res (2009) 3.17
Analysis of the reactions used for the preparation of drug candidate molecules. Org Biomol Chem (2006) 3.12
Catalytic dehydrogenative cross-coupling: forming carbon-carbon bonds by oxidizing two carbon-hydrogen bonds. Chem Rev (2011) 2.88
A new palladium precatalyst allows for the fast Suzuki-Miyaura coupling reactions of unstable polyfluorophenyl and 2-heteroaryl boronic acids. J Am Chem Soc (2010) 2.73
A new class of easily activated palladium precatalysts for facile C-N cross-coupling reactions and the low temperature oxidative addition of aryl chlorides. J Am Chem Soc (2008) 2.61
Palladium-catalyzed alpha-arylation of carbonyl compounds and nitriles. Acc Chem Res (2003) 2.47
Transition-metal-catalyzed direct arylation of (hetero)arenes by C-H bond cleavage. Angew Chem Int Ed Engl (2009) 2.29
Towards mild metal-catalyzed C-H bond activation. Chem Soc Rev (2011) 2.27
Carboxylate-assisted transition-metal-catalyzed C-H bond functionalizations: mechanism and scope. Chem Rev (2011) 2.17
Selected patented cross-coupling reaction technologies. Chem Rev (2006) 2.15
Palladium-catalyzed cross-coupling: a historical contextual perspective to the 2010 Nobel Prize. Angew Chem Int Ed Engl (2012) 2.07
Organometallic chemistry: C-H activation. Nature (2007) 2.00
Design and Preparation of New Palladium Precatalysts for C-C and C-N Cross-Coupling Reactions. Chem Sci (2013) 1.96
Chemical Synthesis of Natural Product Peptides: Coupling Methods for the Incorporation of Noncoded Amino Acids into Peptides. Chem Rev (1997) 1.93
The development of versatile methods for palladium-catalyzed coupling reactions of aryl electrophiles through the use of P(t-Bu)3 and PCy3 as ligands. Acc Chem Res (2008) 1.75
An experimental and computational approach to defining structure/reactivity relationships for intramolecular addition reactions to bicyclic epoxonium ions. J Am Chem Soc (2007) 1.70
Functionalization of organic molecules by transition-metal-catalyzed C(sp3)-H activation. Chemistry (2010) 1.69
Recent advances in aryl-aryl bond formation by direct arylation. Chem Soc Rev (2009) 1.67
Large-scale applications of transition metal-catalyzed couplings for the synthesis of pharmaceuticals. Chem Rev (2011) 1.65
Sigma-chelation-directed C-H functionalizations using Pd(II) and Cu(II) catalysts: regioselectivity, stereoselectivity and catalytic turnover. Org Biomol Chem (2006) 1.53
Direct C-H transformation via iron catalysis. Chem Rev (2010) 1.52
An improved system for the palladium-catalyzed borylation of aryl halides with pinacol borane. J Org Chem (2008) 1.45
Transition metal-catalyzed direct arylation of substrates with activated sp3-hybridized C-H bonds and some of their synthetic equivalents with aryl halides and pseudohalides. Chem Rev (2010) 1.44
Palladium-catalyzed C(sp3)-H arylation of diarylmethanes at room temperature: synthesis of triarylmethanes via deprotonative-cross-coupling processes. J Am Chem Soc (2012) 1.43
Catalytic enantioselective Meerwein-Eschenmoser Claisen rearrangement: asymmetric synthesis of allyl oxindoles. J Am Chem Soc (2008) 1.42
Palladium-catalyzed enantioselective alpha-arylation and alpha-vinylation of oxindoles facilitated by an axially chiral P-stereogenic ligand. J Am Chem Soc (2009) 1.41
Synthesis and application of palladium precatalysts that accommodate extremely bulky di-tert-butylphosphino biaryl ligands. Org Lett (2013) 1.38
Improved catalysts for the palladium-catalyzed synthesis of oxindoles by amide alpha-arylation. Rate acceleration, use of aryl chloride substrates, and a new carbene ligand for asymmetric transformations. J Org Chem (2001) 1.37
Metal-catalyzed alpha-arylation of carbonyl and related molecules: novel trends in C-C bond formation by C-H bond functionalization. Angew Chem Int Ed Engl (2010) 1.35
Ligand-enabled methylene C(sp3)-H bond activation with a Pd(II) catalyst. J Am Chem Soc (2012) 1.23
Transition metal-catalyzed arylation of unactivated C(sp3)-H bonds. Chem Soc Rev (2011) 1.22
Enantioselective synthesis of 3,3-disubstituted oxindoles through Pd-catalyzed cyanoamidation. Org Lett (2008) 1.22
Asymmetric cross-coupling of aryl triflates to the benzylic position of benzylamines. Angew Chem Int Ed Engl (2012) 1.17
Chemistry and biology of diazonamide A: second total synthesis and biological investigations. J Am Chem Soc (2004) 1.16
N-Acylbenzotriazoles: neutral acylating reagents for the preparation of primary, secondary, and tertiary amides J Org Chem (2000) 1.15
Palladium-catalyzed direct intermolecular α-arylation of amides with aryl chlorides. Org Lett (2013) 1.15
Palladium-catalyzed direct α-arylation of methyl sulfones with aryl bromides. Org Lett (2013) 1.14
Synthesis of polyarylated methanes through cross-coupling of tricarbonylchromium-activated benzyllithiums. Angew Chem Int Ed Engl (2010) 1.13
Palladium-catalyzed alpha-arylation of esters. J Am Chem Soc (2001) 1.13
Palladium-catalyzed direct arylation of methyl sulfoxides with aryl halides. J Am Chem Soc (2013) 1.09
Palladium-catalyzed allylic substitution with (η6-arene-CH2Z)Cr(CO)(3)-based nucleophiles. J Am Chem Soc (2011) 1.07
Mild and general conditions for negishi cross-coupling enabled by the use of palladacycle precatalysts. Angew Chem Int Ed Engl (2012) 1.06
Easily accessible and highly tunable indolyl phosphine ligands for Suzuki-Miyaura coupling of aryl chlorides. Org Lett (2007) 1.05
Bulky chiral carbene ligands and their application in the palladium-catalyzed asymmetric intramolecular alpha-arylation of amides. Angew Chem Int Ed Engl (2007) 1.05
A catalytic approach for the functionalization of C(sp3)-H bonds. Angew Chem Int Ed Engl (2006) 1.04
Enantioselective synthesis of SM-130686 based on the development of asymmetric Cu(I)F catalysis to access 2-oxindoles containing a tetrasubstituted carbon. J Am Chem Soc (2009) 1.04
Palladium-catalyzed intermolecular alpha-arylation of zinc amide enolates under mild conditions. J Am Chem Soc (2006) 1.03
Phosphonium salts as chiral phase-transfer catalysts: asymmetric Michael and Mannich reactions of 3-aryloxindoles. Angew Chem Int Ed Engl (2009) 0.99
Palladium-catalyzed alpha-arylation of esters and amides under more neutral conditions. J Am Chem Soc (2003) 0.99
Orthogonal Pd- and Cu-based catalyst systems for C- and N-arylation of oxindoles. J Am Chem Soc (2008) 0.98
Thiourea-catalyzed highly enantio- and diastereoselective additions of oxindoles to nitroolefins: application to the formal synthesis of (+)-physostigmine. J Am Chem Soc (2009) 0.97
Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Bioorg Med Chem Lett (2012) 0.97
Mild palladium-catalyzed selective monoarylation of nitriles. J Am Chem Soc (2005) 0.96
Catalytic enantioselective construction of beta-quaternary carbons via a conjugate addition of cyanide to beta,beta-disubstituted alpha,beta-unsaturated carbonyl compounds. J Am Chem Soc (2010) 0.95
Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles. Chem Commun (Camb) (2009) 0.95
Metal-catalyzed direct alkylations of (hetero)arenes via C-H bond cleavages with unactivated alkyl halides. Chem Commun (Camb) (2010) 0.93
Highly enantioselective and organocatalytic alpha-amination of 2-oxindoles. Org Lett (2009) 0.93
Palladium-catalyzed alpha-arylation of oxindoles. Org Lett (2008) 0.93
Addition of organocerium reagents to morpholine amides: synthesis of important pheromone components of Achaea janata. J Org Chem (2002) 0.93
Palladium-catalyzed aminocarbonylation of aryl chlorides at atmospheric pressure: the dual role of sodium phenoxide. Angew Chem Int Ed Engl (2007) 0.93
Cross-coupling of C(sp)-H Bonds with Organometallic Reagents via Pd(II)/Pd(0) Catalysis** Isr J Chem (2010) 0.91
Beyond traditional cross couplings: the scope of the cross dehydrogenative coupling reaction. Chem Asian J (2010) 0.91
Atom economy. Palladium-catalyzed formation of coumarins by addition of phenols and alkynoates via a net C-H insertion. J Am Chem Soc (2003) 0.90
Inherently chiral concave molecules--from synthesis to applications. Chem Soc Rev (2010) 0.90
Asymmetric alpha-alkylation of N'-tert-butanesulfinyl amidines. Application to the total synthesis of (6R,7S)-7-amino-7,8-dihydro-alpha-bisabolene. J Am Chem Soc (2004) 0.89
The palladium catalyzed asymmetric addition of oxindoles and allenes: an atom-economical versatile method for the construction of chiral indole alkaloids. J Am Chem Soc (2011) 0.88
Pd-catalyzed alpha-arylation of trimethylsilyl enol ethers with aryl bromides and chlorides: a synergistic effect of two metal fluorides as additives. Angew Chem Int Ed Engl (2006) 0.88
Retracted Highly enantioselective intramolecular cyanoamidation: (+)-horsfiline, (-)-coerulescine, and (-)-esermethole. Org Lett (2010) 0.88
A new generation of air stable, highly active Pd complexes for C--C and C--N coupling reactions with aryl chlorides. Angew Chem Int Ed Engl (2002) 0.87
Highly chemo- and enantioselective synthesis of 3-allyl-3-aryl oxindoles via the direct palladium-catalyzed alpha-arylation of amides. Org Lett (2010) 0.87
Total synthesis of rapamycin. Angew Chem Int Ed Engl (2007) 0.86
Total synthesis of the protein phosphatase 2A inhibitor lactodehydrothyrsiferol. Angew Chem Int Ed Engl (2011) 0.86
A homodinuclear Mn(III)2-Schiff base complex for catalytic asymmetric 1,4-additions of oxindoles to nitroalkenes. J Am Chem Soc (2009) 0.86
Tosylhydrazones: new uses for classic reagents in palladium-catalyzed cross-coupling and metal-free reactions. Angew Chem Int Ed Engl (2011) 0.85
Addressing challenges in palladium-catalyzed cross-coupling reactions through ligand design. Chemistry (2012) 0.84
Synthesis of 3-fluoro-3-aryl oxindoles: direct enantioselective α arylation of amides. Angew Chem Int Ed Engl (2012) 0.84
Organocatalytic asymmetric allylic alkylation of oxindoles with Morita-Baylis-Hillman carbonates. Chem Commun (Camb) (2009) 0.83
Total synthesis of (-)-strychnine. J Am Chem Soc (2004) 0.82
N-tosylhydrazones: versatile reagents for metal-catalyzed and metal-free cross-coupling reactions. Chem Soc Rev (2011) 0.82
Tacrolimus strongly inhibits multiple human UDP-glucuronosyltransferase (UGT) isoforms. Pharmazie (2012) 0.81
Palladium-catalyzed decarboxylative arylation of potassium cyanoacetate: synthesis of α-diaryl nitriles from aryl halides. Org Lett (2011) 0.81
Copper-catalyzed arylation of o-bromoanilides: highly flexible synthesis of hexahydropyrroloindole alkaloids. Org Lett (2012) 0.80
Synthesis, characterization, and reactivity of arylpalladium cyanoalkyl complexes: selection of catalysts for the alpha-arylation of nitriles. J Am Chem Soc (2002) 0.80
Palladium-catalyzed direct arylation of heteroarenes with aryl mesylates. Chemistry (2010) 0.80
Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles. Angew Chem Int Ed Engl (2009) 0.80
Structure-activity studies of echinomycin antibiotics against drug-resistant and biofilm-forming Staphylococcus aureus and Enterococcus faecalis. Bioorg Med Chem Lett (2009) 0.80
A general method for the direct alpha-arylation of nitriles with aryl chlorides. Angew Chem Int Ed Engl (2003) 0.80
Synthesis of chiral N-heterocyclic carbene ligands with rigid backbones and application to the palladium-catalyzed enantioselective intramolecular α-arylation of amides. Org Lett (2011) 0.79
Matching the chirality of monodentate N-heterocyclic carbene ligands: a case study on well-defined palladium complexes for the asymmetric alpha-arylation of amides. Org Lett (2008) 0.79
Synthesis of enantiomerically enriched 3-amino-2-oxindoles through a palladium-mediated asymmetric intramolecular arylation of α-ketimino amides. Org Lett (2012) 0.78
Palladium-catalyzed intermolecular alpha-arylation of N-protected 2-piperidinones. Org Lett (2003) 0.78
Practical synthesis of unsymmetrical tetraarylethylenes and their application for the preparation of [triphenylethylene-spacer-triphenylethylene] triads. J Org Chem (2007) 0.77
Fischer indole synthesis with organozinc reagents. Angew Chem Int Ed Engl (2010) 0.77
Total synthesis and cytotoxicity studies of a cyclic depsipeptide with proposed structure of palau'amide. Org Lett (2005) 0.77
Transition-metal-free synthesis of oxindoles by potassium tert-butoxide-promoted intramolecular α-arylation. Org Lett (2012) 0.76
Cyclosporins from Mycelium sterilae MS 2929. J Nat Prod (2009) 0.76
Palladium-Catalyzed α-Arylation of Methyl Sulfonamides with Aryl Chlorides. Adv Synth Catal (2016) 0.75
Organocatalytic Synthesis of Alkynes. J Am Chem Soc (2015) 0.75