PubRank

Enrico O Purisima

Author PubWeight™ 40.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Principles of microRNA regulation of a human cellular signaling network. Mol Syst Biol 2006 3.27
2 Identification of high-quality cancer prognostic markers and metastasis network modules. Nat Commun 2010 2.54
3 A map of human cancer signaling. Mol Syst Biol 2007 2.50
4 MicroRNAs preferentially target the genes with high transcriptional regulation complexity. Biochem Biophys Res Commun 2006 1.88
5 Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 1. Exploring the parameter space. J Chem Inf Model 2007 1.68
6 MicroRNA regulation and interspecific variation of gene expression. Trends Genet 2007 1.39
7 Deubiquitination, a new function of the severe acute respiratory syndrome coronavirus papain-like protease? J Virol 2005 1.37
8 Protein evolution on a human signaling network. BMC Syst Biol 2009 1.25
9 Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex. J Mol Biol 2008 1.13
10 Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides. J Med Chem 2002 0.98
11 Exhaustive docking and solvated interaction energy scoring: lessons learned from the SAMPL4 challenge. J Comput Aided Mol Des 2014 0.93
12 Binding site-based classification of coronaviral papain-like proteases. Proteins 2006 0.91
13 Solvated interaction energy (SIE) for scoring protein-ligand binding affinities. 2. Benchmark in the CSAR-2010 scoring exercise. J Chem Inf Model 2011 0.90
14 On the transferability of hydration-parametrized continuum electrostatics models to solvated binding calculations. J Comput Chem 2003 0.90
15 Molecular dynamics study of small molecule inhibitors of the Bcl-2 family. Proteins 2011 0.89
16 Impaired helix 12 dynamics due to proline 892 substitutions in the androgen receptor are associated with complete androgen insensitivity. Hum Mol Genet 2006 0.86
17 Prediction of SAMPL-1 hydration free energies using a continuum electrostatics-dispersion model. J Phys Chem B 2009 0.85
18 Viral cystatin evolution and three-dimensional structure modelling: a case of directional selection acting on a viral protein involved in a host-parasitoid interaction. BMC Biol 2008 0.84
19 Trapping open and closed forms of FitE: a group III periplasmic binding protein. Proteins 2009 0.84
20 Molecular surface generation using a variable-radius solvent probe. Proteins 2006 0.84
21 Predicting hydration free energies of polychlorinated aromatic compounds from the SAMPL-3 data set with FiSH and LIE models. J Comput Aided Mol Des 2011 0.83
22 Profiling charge complementarity and selectivity for binding at the protein surface. Biophys J 2003 0.83
23 A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist. Biochim Biophys Acta 2010 0.82
24 Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway. J Biol Chem 2009 0.82
25 Carboxy-monopeptidase substrate specificity of human cathepsin X. Biochem Biophys Res Commun 2005 0.81
26 Contribution of active site residues to substrate hydrolysis by USP2: insights into catalysis by ubiquitin specific proteases. Biochemistry 2011 0.81
27 The solvated interaction energy method for scoring binding affinities. Methods Mol Biol 2012 0.80
28 Exhaustive search and solvated interaction energy (SIE) for virtual screening and affinity prediction. J Comput Aided Mol Des 2011 0.80
29 Exploring inhibitor binding at the S' subsites of cathepsin L. J Med Chem 2008 0.79
30 Implications of the reactive thiol and the proximal non-proline cis-peptide bond in the Structure and function of Vibrio harveyi luciferase. Biochemistry 2002 0.79
31 Coupled atomic charge selectivity for optimal ligand-charge distributions at protein binding sites. J Comput Chem 2006 0.79
32 Bridging structural biology and genetics by computational methods: an investigation into how the R774C mutation in the AR gene can result in complete androgen insensitivity syndrome. Hum Mutat 2003 0.78
33 An investigation into CAG repeat length variation and N/C terminal interactions in the T877A mutant androgen receptor found in prostate cancer. J Steroid Biochem Mol Biol 2008 0.77
34 A fast pairwise evaluation of molecular surface area. J Comput Chem 2002 0.77
35 Small-molecule ligands of GD2 ganglioside, designed from NMR studies, exhibit induced-fit binding and bioactivity. Chem Biol 2010 0.77
36 A combined crystallographic and molecular dynamics study of cathepsin L retrobinding inhibitors. J Med Chem 2009 0.77
37 Effect of limited solid-state glycation on the conformation of lysozyme by ESI-MSMS peptide mapping and molecular modeling. Bioconjug Chem 2004 0.76
38 Inhibition of a cathepsin L-like cysteine protease by a chimeric propeptide-derived inhibitor. Biochemistry 2005 0.75
39 Solvation models: theory and validation. Curr Pharm Des 2014 0.75
40 Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding? J Med Chem 2014 0.75