| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
para-Functionalized aryl-di-tert-butylfluorosilanes as potential labeling synthons for (18)F radiopharmaceuticals.
|
Chemistry
|
2009
|
1.18
|
|
2
|
Parametric mapping of binding in human brain of D2 receptor ligands of different affinities.
|
J Nucl Med
|
2005
|
1.15
|
|
3
|
The temporal dynamics of poststroke neuroinflammation: a longitudinal diffusion tensor imaging-guided PET study with 11C-PK11195 in acute subcortical stroke.
|
J Nucl Med
|
2010
|
1.11
|
|
4
|
A universally applicable 68Ga-labeling technique for proteins.
|
J Nucl Med
|
2011
|
1.10
|
|
5
|
Synthesis of p-(di-tert-butyl[(18)F]fluorosilyl)benzaldehyde ([(18)F]SiFA-A) with high specific activity by isotopic exchange: a convenient labeling synthon for the (18)F-labeling of N-amino-oxy derivatized peptides.
|
Bioconjug Chem
|
2007
|
1.03
|
|
6
|
(89)Zr, a radiometal nuclide with high potential for molecular imaging with PET: chemistry, applications and remaining challenges.
|
Molecules
|
2013
|
1.01
|
|
7
|
Kit-like 18F-labeling of proteins: synthesis of 4-(di-tert-butyl[18F]fluorosilyl)benzenethiol (Si[18F]FA-SH) labeled rat serum albumin for blood pool imaging with PET.
|
Bioconjug Chem
|
2009
|
1.01
|
|
8
|
One-step (18)F-labeling of peptides for positron emission tomography imaging using the SiFA methodology.
|
Nat Protoc
|
2012
|
1.00
|
|
9
|
Generation of novel single-chain antibodies by phage-display technology to direct imaging agents highly selective to pancreatic beta- or alpha-cells in vivo.
|
Diabetes
|
2009
|
0.97
|
|
10
|
Where in-vivo imaging meets cytoarchitectonics: the relationship between cortical thickness and neuronal density measured with high-resolution [18F]flumazenil-PET.
|
Neuroimage
|
2010
|
0.94
|
|
11
|
Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death.
|
J Pharmacol Exp Ther
|
2004
|
0.93
|
|
12
|
Synthesis of [(18)F]SiFB: a prosthetic group for direct protein radiolabeling for application in positron emission tomography.
|
Nat Protoc
|
2012
|
0.92
|
|
13
|
External awareness and GABA--a multimodal imaging study combining fMRI and [18F]flumazenil-PET.
|
Hum Brain Mapp
|
2012
|
0.91
|
|
14
|
Preparation of water-soluble maleimide-functionalized 3 nm gold nanoparticles: a new bioconjugation template.
|
Langmuir
|
2012
|
0.90
|
|
15
|
[18F]azadibenzocyclooctyne ([18F]ADIBO): a biocompatible radioactive labeling synthon for peptides using catalyst free [3+2] cycloaddition.
|
Bioorg Med Chem Lett
|
2011
|
0.90
|
|
16
|
Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent.
|
Bioorg Med Chem Lett
|
2004
|
0.90
|
|
17
|
Protein labeling with the labeling precursor [(18)F]SiFA-SH for positron emission tomography.
|
Nat Protoc
|
2012
|
0.90
|
|
18
|
Multimodal microglia imaging of fiber tracts in acute subcortical stroke.
|
Ann Neurol
|
2009
|
0.89
|
|
19
|
Oxalic acid supported Si-18F-radiofluorination: one-step radiosynthesis of N-succinimidyl 3-(di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for protein labeling.
|
Bioconjug Chem
|
2012
|
0.89
|
|
20
|
Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases.
|
Bioconjug Chem
|
2006
|
0.88
|
|
21
|
One-step ¹⁸F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET).
|
Bioconjug Chem
|
2010
|
0.87
|
|
22
|
Basal opioid receptor binding is associated with differences in sensory perception in healthy human subjects: a [18F]diprenorphine PET study.
|
Neuroimage
|
2009
|
0.86
|
|
23
|
Synthesis of 3-chloro-6-((4-(di-tert-butyl[(18)F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([(18)F]SiFA-OTz) for rapid tetrazine-based (18)F-radiolabeling.
|
Chem Commun (Camb)
|
2015
|
0.85
|
|
24
|
[68Ga]-albumin-PET in the monitoring of left ventricular function in murine models of ischemic and dilated cardiomyopathy: comparison with cardiac MRI.
|
Mol Imaging Biol
|
2013
|
0.85
|
|
25
|
Evaluation of an automated double-synthesis module: efficiency and reliability of subsequent radiosyntheses of FHBG and FLT.
|
Nucl Med Biol
|
2011
|
0.83
|
|
26
|
Synthesis and preliminary evaluation of (R,R)(S,S) 5-(2-(2-[4-(2-[(18)F]fluoroethoxy)phenyl]-1-methylethylamino)-1-hydroxyethyl)-benzene-1,3-diol ([(18)F]FEFE) for the in vivo visualisation and quantification of the beta2-adrenergic receptor status in lung.
|
Bioorg Med Chem Lett
|
2003
|
0.82
|
|
27
|
Multimerization of cRGD peptides by click chemistry: synthetic strategies, chemical limitations, and influence on biological properties.
|
Chembiochem
|
2010
|
0.82
|
|
28
|
Improved work-up procedure for the production of [(18)F]flumazenil and first results of its use with a high-resolution research tomograph in human stroke.
|
Nucl Med Biol
|
2009
|
0.82
|
|
29
|
Opioid receptor PET reveals the psychobiologic correlates of reward processing.
|
J Nucl Med
|
2008
|
0.81
|
|
30
|
GABA(A) receptors in visual and auditory cortex and neural activity changes during basic visual stimulation.
|
Front Hum Neurosci
|
2012
|
0.81
|
|
31
|
Synthesis and in vitro and in vivo evaluation of SiFA-tagged bombesin and RGD peptides as tumor imaging probes for positron emission tomography.
|
Bioconjug Chem
|
2014
|
0.81
|
|
32
|
Synthesis of 131I-labeled glucose-conjugated inhibitors of O6-methylguanine-DNA methyltransferase (MGMT) and comparison with nonconjugated inhibitors as potential tools for in vivo MGMT imaging.
|
J Med Chem
|
2006
|
0.81
|
|
33
|
GABAA receptors predict aversion-related brain responses: an fMRI-PET investigation in healthy humans.
|
Neuropsychopharmacology
|
2013
|
0.80
|
|
34
|
Radiolabeled heterobivalent peptidic ligands: an approach with high future potential for in vivo imaging and therapy of malignant diseases.
|
ChemMedChem
|
2013
|
0.80
|
|
35
|
Rapid (18)F-labeling and loading of PEGylated gold nanoparticles for in vivo applications.
|
Bioconjug Chem
|
2014
|
0.79
|
|
36
|
t-Bu2SiF-derivatized D2-receptor ligands: the first SiFA-containing small molecule radiotracers for target-specific PET-imaging.
|
Molecules
|
2011
|
0.78
|
|
37
|
Chemical modification of single walled carbon nanotubes with tetrazine-tethered gold nanoparticles via a Diels-Alder reaction.
|
Chem Commun (Camb)
|
2013
|
0.78
|
|
38
|
DOTA derivatives for site-specific biomolecule-modification via click chemistry: synthesis and comparison of reaction characteristics.
|
Bioorg Med Chem
|
2010
|
0.78
|
|
39
|
Towards tropomyosin-related kinase B (TrkB) receptor ligands for brain imaging with PET: radiosynthesis and evaluation of 2-(4-[(18)F]fluorophenyl)-7,8-dihydroxy-4H-chromen-4-one and 2-(4-([N-methyl-(11)C]-dimethylamino)phenyl)-7,8-dihydroxy-4H-chromen-4-one.
|
Bioorg Med Chem
|
2013
|
0.78
|
|
40
|
Establishment and functional validation of a structural homology model for human DNA methyltransferase 1.
|
Biochem Biophys Res Commun
|
2003
|
0.77
|
|
41
|
Simple and convenient radiolabeling of proteins using a prelabeling-approach with thiol-DOTA.
|
Bioorg Med Chem Lett
|
2009
|
0.77
|
|
42
|
Positron emission tomography in the assessment of left ventricular function in healthy rats: a comparison of four imaging methods.
|
J Nucl Cardiol
|
2012
|
0.77
|
|
43
|
A Nutritional Perspective of Ketogenic Diet in Cancer: A Narrative Review.
|
J Acad Nutr Diet
|
2017
|
0.76
|
|
44
|
Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?
|
J Med Chem
|
2014
|
0.75
|
|
45
|
Radiosynthesis and Preclinical Evaluation of (18)F-Fluoroglycosylated Octreotate for Somatostatin Receptor Imaging.
|
Bioconjug Chem
|
2016
|
0.75
|
|
46
|
PESIN multimerization improves receptor avidities and in vivo tumor targeting properties to GRPR-overexpressing tumors.
|
Bioconjug Chem
|
2014
|
0.75
|
|
47
|
Temporal changes in phosphatidylserine expression and glucose metabolism after myocardial infarction: an in vivo imaging study in mice.
|
Mol Imaging
|
2012
|
0.75
|
|
48
|
Fully automated SPE-based synthesis and purification of 2-[18F]fluoroethyl-choline for human use.
|
Nucl Med Biol
|
2010
|
0.75
|
|
49
|
Direct one-step labeling of cysteine residues on peptides with [(11)C]methyl triflate for the synthesis of PET radiopharmaceuticals.
|
Amino Acids
|
2013
|
0.75
|
|
50
|
In vitro and initial in vivo evaluation of (68)Ga-labeled transferrin receptor (TfR) binding peptides as potential carriers for enhanced drug transport into TfR expressing cells.
|
Mol Imaging Biol
|
2011
|
0.75
|
|
51
|
Syntheses and evaluation of carbon-11- and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET imaging agents.
|
ACS Chem Neurosci
|
2014
|
0.75
|
|
52
|
18F-Radiolabeling and In Vivo Analysis of SiFA-derivatized Polymeric Core-Shell Nanoparticles.
|
Bioconjug Chem
|
2017
|
0.75
|