Extensive recombination-induced disruption of genetic interactions is highly deleterious but can be partially reversed by small numbers of secondary recombination events.

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Published in J Virol on April 30, 2014

Authors

Adérito L Monjane1, Darren P Martin2, Francisco Lakay3, Brejnev M Muhire4, Daniel Pande5, Arvind Varsani6, Gordon Harkins7, Dionne N Shepherd3, Edward P Rybicki1

Author Affiliations

1: Molecular and Cell Biology Department, University of Cape Town, Cape Town, South Africa Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
2: Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa darrenpatrickmartin@gmail.com.
3: Molecular and Cell Biology Department, University of Cape Town, Cape Town, South Africa.
4: Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
5: Department of Botany and Horticulture, Maseno University, Maseno, Kenya.
6: School of Biological Sciences and Biomolecular Interaction Centre, University of Canterbury, Christchurch, New Zealand Department of Plant Pathology and Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA Electron Microscope Unit, Division of Medical Biochemistry, Department of Clinical Laboratory Sciences, University of Cape Town, Cape Town, South Africa.
7: South African National Bioinformatics Institute, MRC Unit for Bioinformatics Capacity Development, University of the Western Cape, Bellville, South Africa.

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